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The map label for this gene is msrB [H]

Identifier: 45658631

GI number: 45658631

Start: 3406421

End: 3406921

Strand: Direct

Name: msrB [H]

Synonym: LIC12800

Alternate gene names: 45658631

Gene position: 3406421-3406921 (Clockwise)

Preceding gene: 45658629

Following gene: 45658632

Centisome position: 79.64

GC content: 37.72

Gene sequence:

>501_bases
ATGAAAAACAAGATTTTACTCTCAATTATCGTGATATGTTTTGGATTTATTAGTTGTTTAAAGACAAATGGAGATTCAAA
TCAAACAAACTCTAAAGGAGGAATGATGAATTACGAAGTCAACAAATCTGATGAGGATTGGAAAAAAGAACTCACTCCAG
AACAATATAGAATTTTAAGACAAAAGGGAACCGAGATGGCTTTTACCGGAGCTCTGTATAAAAATCAAGATAAAGGCACC
TATGTTTGTGCGGCCTGCGGCGCCGTTTTATTTTCTTCTGACACTAAGTATGAATCCGGTTCCGGCTGGCCTTCTTTTTA
TCAGCCTGTTAAAGACGGGGTAGTCGACAAACAAAAAGATAGTAGCCATGGAATGGAGAGAACGGAAATTCTTTGTTCTA
AATGCGGAGGACATCTAGGTCACGTTTTCAATGATGGACCAAGACCTACTGGATTGCGTTATTGTATCAATTCCGCTTCC
TTAAAGTTTCAGAAAGAATAA

Upstream 100 bases:

>100_bases
AAAACTTTCCTTTTAAAGCTTTATAAATAGAAAAATTCTTATCTATACTGATAATTCATTTTTCAGGTAACCAATTCAAA
ATAAAAACGAATTTTTCATT

Downstream 100 bases:

>100_bases
AATCAATATAACTTCCTTAGATTCTCGGAAAAGTTTCTACTTTCTTTTTTTGATTTTCAAGTTGTGGTGATAAGGAAAAT
CATACCTAAATCCGGATTCA

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MKNKILLSIIVICFGFISCLKTNGDSNQTNSKGGMMNYEVNKSDEDWKKELTPEQYRILRQKGTEMAFTGALYKNQDKGT
YVCAACGAVLFSSDTKYESGSGWPSFYQPVKDGVVDKQKDSSHGMERTEILCSKCGGHLGHVFNDGPRPTGLRYCINSAS
LKFQKE

Sequences:

>Translated_166_residues
MKNKILLSIIVICFGFISCLKTNGDSNQTNSKGGMMNYEVNKSDEDWKKELTPEQYRILRQKGTEMAFTGALYKNQDKGT
YVCAACGAVLFSSDTKYESGSGWPSFYQPVKDGVVDKQKDSSHGMERTEILCSKCGGHLGHVFNDGPRPTGLRYCINSAS
LKFQKE
>Mature_166_residues
MKNKILLSIIVICFGFISCLKTNGDSNQTNSKGGMMNYEVNKSDEDWKKELTPEQYRILRQKGTEMAFTGALYKNQDKGT
YVCAACGAVLFSSDTKYESGSGWPSFYQPVKDGVVDKQKDSSHGMERTEILCSKCGGHLGHVFNDGPRPTGLRYCINSAS
LKFQKE

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=127, Percent_Identity=51.9685039370079, Blast_Score=147, Evalue=4e-36,
Organism=Homo sapiens, GI301336162, Length=127, Percent_Identity=51.9685039370079, Blast_Score=147, Evalue=4e-36,
Organism=Homo sapiens, GI73089054, Length=127, Percent_Identity=51.9685039370079, Blast_Score=147, Evalue=4e-36,
Organism=Homo sapiens, GI37620216, Length=138, Percent_Identity=50, Blast_Score=147, Evalue=4e-36,
Organism=Homo sapiens, GI117606353, Length=139, Percent_Identity=44.6043165467626, Blast_Score=131, Evalue=3e-31,
Organism=Homo sapiens, GI7706511, Length=98, Percent_Identity=43.8775510204082, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI1788077, Length=121, Percent_Identity=55.3719008264463, Blast_Score=144, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17553450, Length=140, Percent_Identity=46.4285714285714, Blast_Score=129, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI115532676, Length=140, Percent_Identity=46.4285714285714, Blast_Score=129, Evalue=7e-31,
Organism=Saccharomyces cerevisiae, GI6319816, Length=130, Percent_Identity=42.3076923076923, Blast_Score=111, Evalue=4e-26,
Organism=Drosophila melanogaster, GI221378664, Length=127, Percent_Identity=51.1811023622047, Blast_Score=133, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24645799, Length=144, Percent_Identity=45.1388888888889, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI45553335, Length=125, Percent_Identity=50.4, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21356369, Length=125, Percent_Identity=50.4, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI221378662, Length=134, Percent_Identity=48.5074626865672, Blast_Score=130, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24645801, Length=155, Percent_Identity=42.5806451612903, Blast_Score=127, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24645804, Length=137, Percent_Identity=45.2554744525547, Blast_Score=127, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 18475; Mature: 18475

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKILLSIIVICFGFISCLKTNGDSNQTNSKGGMMNYEVNKSDEDWKKELTPEQYRILR
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHCCHHHHHHHH
QKGTEMAFTGALYKNQDKGTYVCAACGAVLFSSDTKYESGSGWPSFYQPVKDGVVDKQKD
HCCCCEEEEHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCC
SSHGMERTEILCSKCGGHLGHVFNDGPRPTGLRYCINSASLKFQKE
CCCCHHHHHHHHHHHCCHHCHHCCCCCCCCHHHHHHCCCCEEEECC
>Mature Secondary Structure
MKNKILLSIIVICFGFISCLKTNGDSNQTNSKGGMMNYEVNKSDEDWKKELTPEQYRILR
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHCCHHHHHHHH
QKGTEMAFTGALYKNQDKGTYVCAACGAVLFSSDTKYESGSGWPSFYQPVKDGVVDKQKD
HCCCCEEEEHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCC
SSHGMERTEILCSKCGGHLGHVFNDGPRPTGLRYCINSASLKFQKE
CCCCHHHHHHHHHHHCCHHCHHCCCCCCCCHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA