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The map label for this gene is coaX [H]

Identifier: 45658623

GI number: 45658623

Start: 3399054

End: 3399827

Strand: Reverse

Name: coaX [H]

Synonym: LIC12792

Alternate gene names: 45658623

Gene position: 3399827-3399054 (Counterclockwise)

Preceding gene: 45658624

Following gene: 45658618

Centisome position: 79.49

GC content: 37.98

Gene sequence:

>774_bases
ATGCTTTTAGTAGTAGATGTCGGTAATACGAACACCGTTTTCGGAATTTTTGAAAATGGAAACAAGATTCCTCTCTTTCA
CAAACGAACCGTAACTAGAAAGGATCGAACGTCCGATGAACTAGGTTTGTTCTTCAGAGGATTTTTAAGAGAATTTAAAA
TCGAAAACGAAATGATCACTGGCGGGATCTATTCCAGCGTCGTACCTACTTTAAATCCTATCTTAGATAGAATGTTTCAA
GATTGGTTTAAGATAGAGGCGATTCGAGTTCATTATCAAATGAAACTGCCTTTTTCCATTTCTTATCCAAGACCTTATGA
AATCGGAGCAGATCGACTTGTAAACGCCGCCACTTGTGCGATCGATTTTCCGGGTAAGTCTATCATTATCGATTTAGGAA
CCGCGACTACATTTTGTGTGGTGAACGAAAAACCAGAGTATTTAGGAGGAGTAATCGCTCCTGGTTTAAAAGTTTCTATG
GACGCGTTAACAAGAAATACTTCTCAACTTCCTCCAATTGTATTTCAGTCTCCTGGAAAAATTTTAGGAGATTCTACGAT
CGAGTCGATTCAAGCAGGATTCTTTTTTGGATGGATCGGTCTTTTGGAAGGGATTATTCGTGAAATCAAAAAAGATAAAG
GACAGGATTATCAAGTTATTGGAACCGGTGGTTTGGTAACCGTAATCGATGCTGCTCATCCAGGAATTTTTGATAAAATC
GATCCGCTTCTGACTTTGCGAGGATTACAAATTTTACACTTAATGAATTCTTAA

Upstream 100 bases:

>100_bases
GAAGGACTGAGTGAAAACGGTTCTTTAATTTTAAAAACTCCTTCTGGAACCAGGTTGGATTTTATTGACAGTCCGGAGGA
TTTCCATTCTCTAAACTAAA

Downstream 100 bases:

>100_bases
TTTAAGATAAATTTAATATAGAGCTGTCCTATAAATTCTAAATTCCGACCTGCAGAGCGACCGTAGAAGCGATACATTGA
GTTTAGAGAGGTGTTTGCTG

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MLLVVDVGNTNTVFGIFENGNKIPLFHKRTVTRKDRTSDELGLFFRGFLREFKIENEMITGGIYSSVVPTLNPILDRMFQ
DWFKIEAIRVHYQMKLPFSISYPRPYEIGADRLVNAATCAIDFPGKSIIIDLGTATTFCVVNEKPEYLGGVIAPGLKVSM
DALTRNTSQLPPIVFQSPGKILGDSTIESIQAGFFFGWIGLLEGIIREIKKDKGQDYQVIGTGGLVTVIDAAHPGIFDKI
DPLLTLRGLQILHLMNS

Sequences:

>Translated_257_residues
MLLVVDVGNTNTVFGIFENGNKIPLFHKRTVTRKDRTSDELGLFFRGFLREFKIENEMITGGIYSSVVPTLNPILDRMFQ
DWFKIEAIRVHYQMKLPFSISYPRPYEIGADRLVNAATCAIDFPGKSIIIDLGTATTFCVVNEKPEYLGGVIAPGLKVSM
DALTRNTSQLPPIVFQSPGKILGDSTIESIQAGFFFGWIGLLEGIIREIKKDKGQDYQVIGTGGLVTVIDAAHPGIFDKI
DPLLTLRGLQILHLMNS
>Mature_257_residues
MLLVVDVGNTNTVFGIFENGNKIPLFHKRTVTRKDRTSDELGLFFRGFLREFKIENEMITGGIYSSVVPTLNPILDRMFQ
DWFKIEAIRVHYQMKLPFSISYPRPYEIGADRLVNAATCAIDFPGKSIIIDLGTATTFCVVNEKPEYLGGVIAPGLKVSM
DALTRNTSQLPPIVFQSPGKILGDSTIESIQAGFFFGWIGLLEGIIREIKKDKGQDYQVIGTGGLVTVIDAAHPGIFDKI
DPLLTLRGLQILHLMNS

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis [H]

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004619 [H]

Pfam domain/function: PF03309 Bvg_acc_factor [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 28539; Mature: 28539

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLVVDVGNTNTVFGIFENGNKIPLFHKRTVTRKDRTSDELGLFFRGFLREFKIENEMIT
CEEEEEECCCCEEEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEE
GGIYSSVVPTLNPILDRMFQDWFKIEAIRVHYQMKLPFSISYPRPYEIGADRLVNAATCA
CCHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEECCEEECCCCCCCCCHHHHCCEEEEE
IDFPGKSIIIDLGTATTFCVVNEKPEYLGGVIAPGLKVSMDALTRNTSQLPPIVFQSPGK
EECCCCEEEEEECCCEEEEEECCCHHHHCCEECCCCEEEHHHHHCCCCCCCCEEEECCCC
ILGDSTIESIQAGFFFGWIGLLEGIIREIKKDKGQDYQVIGTGGLVTVIDAAHPGIFDKI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEECCCCCCHHHH
DPLLTLRGLQILHLMNS
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLLVVDVGNTNTVFGIFENGNKIPLFHKRTVTRKDRTSDELGLFFRGFLREFKIENEMIT
CEEEEEECCCCEEEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEE
GGIYSSVVPTLNPILDRMFQDWFKIEAIRVHYQMKLPFSISYPRPYEIGADRLVNAATCA
CCHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEECCEEECCCCCCCCCHHHHCCEEEEE
IDFPGKSIIIDLGTATTFCVVNEKPEYLGGVIAPGLKVSMDALTRNTSQLPPIVFQSPGK
EECCCCEEEEEECCCEEEEEECCCHHHHCCEECCCCEEEHHHHHCCCCCCCCEEEECCCC
ILGDSTIESIQAGFFFGWIGLLEGIIREIKKDKGQDYQVIGTGGLVTVIDAAHPGIFDKI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEECCCCCCHHHH
DPLLTLRGLQILHLMNS
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA