Click here to switch to the map view.

The map label for this gene is nadD

Identifier: 45658603

GI number: 45658603

Start: 3376748

End: 3377347

Strand: Reverse

Name: nadD

Synonym: LIC12770

Alternate gene names: 45658603

Gene position: 3377347-3376748 (Counterclockwise)

Preceding gene: 45658604

Following gene: 45658602

Centisome position: 78.96

GC content: 30.17

Gene sequence:

>600_bases
TTGAATTCTTCCATCCTTACTGGAATTTTTGGAGGAAGTTTTGATCCTCCTCACGAAGGACATTCAGAAATTTTAAAGTC
TTTTTTTTTGGAAGTTCCGGATTGTAAAGAGGTTTTTGTGATTCCAAACCGTCAGAATCCTCTTAAAGAAGAAAAAATTT
CTTTATCCGAAAATATATTAGAAATGTTGAATCTATTTGTTTCCGAGTTTTCGCAATCCATTCGAATTTTGGATTTGGAA
TTGAAACGTAGTGGTCCTAGTTATACAATTCAAACGATTCAAGAGTTAAAGACCATATATCCAAATCGAAAGTTTGTACT
TTTGATTGGAGAAGATAATTATTCCAACTTTCATAAATGGAAAGATTGGGAAAAAATTCTTACCGAAGTAGAAACGATTT
TTGTGTTTCGAAGATTCTCAAAAGAAGTCCCGCTAAATTCTCATCTTAATTCTTTATTTGAATTTAAGTTTTTGGAAAAC
CCTTTAATTCCAGTGACTTCTACGGATTTGAGAAAGTCTTTTTTCCAGTCTAAAGTTCCAAATCTGATTTCAAAAAAAGT
TTTGGATTATATATTAAAAAATAAACTTTATTCTAAATGA

Upstream 100 bases:

>100_bases
ATCCACTGGAAAATTACACGTTCGTGGTCCGATGGGTTTAGTTCATCTTACTACCACAACAACGTATGTCACCGGGAATG
GACAGATCCGGGGTTGATTT

Downstream 100 bases:

>100_bases
GTCGATAAGACTTCATTGTTTGAAATAGTATATTAACTTTCATTGATAATTTTTAGTTTGAATTTAGGAAATTTTCAATA
CACGTCATGCCTCTATAAAA

Product: putative nicotinate-nucleotide adenylyltransferase

Products: NA

Alternate protein names: Deamido-NAD(+) diphosphorylase; Deamido-NAD(+) pyrophosphorylase; Nicotinate mononucleotide adenylyltransferase; NaMN adenylyltransferase

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MNSSILTGIFGGSFDPPHEGHSEILKSFFLEVPDCKEVFVIPNRQNPLKEEKISLSENILEMLNLFVSEFSQSIRILDLE
LKRSGPSYTIQTIQELKTIYPNRKFVLLIGEDNYSNFHKWKDWEKILTEVETIFVFRRFSKEVPLNSHLNSLFEFKFLEN
PLIPVTSTDLRKSFFQSKVPNLISKKVLDYILKNKLYSK

Sequences:

>Translated_199_residues
MNSSILTGIFGGSFDPPHEGHSEILKSFFLEVPDCKEVFVIPNRQNPLKEEKISLSENILEMLNLFVSEFSQSIRILDLE
LKRSGPSYTIQTIQELKTIYPNRKFVLLIGEDNYSNFHKWKDWEKILTEVETIFVFRRFSKEVPLNSHLNSLFEFKFLEN
PLIPVTSTDLRKSFFQSKVPNLISKKVLDYILKNKLYSK
>Mature_199_residues
MNSSILTGIFGGSFDPPHEGHSEILKSFFLEVPDCKEVFVIPNRQNPLKEEKISLSENILEMLNLFVSEFSQSIRILDLE
LKRSGPSYTIQTIQELKTIYPNRKFVLLIGEDNYSNFHKWKDWEKILTEVETIFVFRRFSKEVPLNSHLNSLFEFKFLEN
PLIPVTSTDLRKSFFQSKVPNLISKKVLDYILKNKLYSK

Specific function: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)

COG id: COG1057

COG function: function code H; Nicotinic acid mononucleotide adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadD family

Homologues:

Organism=Escherichia coli, GI1786858, Length=213, Percent_Identity=27.6995305164319, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADD_LEPIC (Q72NR0)

Other databases:

- EMBL:   AE016823
- RefSeq:   YP_002689.1
- ProteinModelPortal:   Q72NR0
- GeneID:   2769981
- GenomeReviews:   AE016823_GR
- KEGG:   lic:LIC12770
- NMPDR:   fig|267671.1.peg.2689
- HOGENOM:   HBG739448
- OMA:   HEGHSEI
- ProtClustDB:   CLSK573675
- BioCyc:   LINT267671:LIC_12770-MONOMER
- HAMAP:   MF_00244
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR005248
- InterPro:   IPR019450
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR12039
- TIGRFAMs:   TIGR00125
- TIGRFAMs:   TIGR00482

Pfam domain/function: PF01467 CTP_transf_2; PF10362 DUF2432

EC number: =2.7.7.18

Molecular weight: Translated: 23296; Mature: 23296

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSSILTGIFGGSFDPPHEGHSEILKSFFLEVPDCKEVFVIPNRQNPLKEEKISLSENIL
CCCCEEEHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHH
EMLNLFVSEFSQSIRILDLELKRSGPSYTIQTIQELKTIYPNRKFVLLIGEDNYSNFHKW
HHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHH
KDWEKILTEVETIFVFRRFSKEVPLNSHLNSLFEFKFLENPLIPVTSTDLRKSFFQSKVP
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
NLISKKVLDYILKNKLYSK
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNSSILTGIFGGSFDPPHEGHSEILKSFFLEVPDCKEVFVIPNRQNPLKEEKISLSENIL
CCCCEEEHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHH
EMLNLFVSEFSQSIRILDLELKRSGPSYTIQTIQELKTIYPNRKFVLLIGEDNYSNFHKW
HHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHH
KDWEKILTEVETIFVFRRFSKEVPLNSHLNSLFEFKFLENPLIPVTSTDLRKSFFQSKVP
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
NLISKKVLDYILKNKLYSK
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA