| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
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The map label for this gene is nuoL
Identifier: 45658584
GI number: 45658584
Start: 3345130
End: 3347079
Strand: Direct
Name: nuoL
Synonym: LIC12750
Alternate gene names: 45658584
Gene position: 3345130-3347079 (Clockwise)
Preceding gene: 45658583
Following gene: 45658585
Centisome position: 78.21
GC content: 42.87
Gene sequence:
>1950_bases ATGGAAATATCTGTACTCATACCCACGTTAGTCGCCCTTCCTTTGATCGGCTTTTTAGTTTCCGGAATTTTCGGCAAATG GTTGAAAGGATTTACGGGAATATTTTCGACAGCGACCGTGTTCGTATCCTTTGCGTTGGCGCTTTTGTCTTTTGTTGACC GGTTTCATCCGATGAGAAACGGAATTCCGAAAATCGTCACCTTATTTCCTTGGATTACTACGGGAGGTTTAAACGTATCC CTCGCCTATCAAGTGGATCAACTTTCCCTTTATATGGTTCTGATCATCACCGGAATCGGATCTCTCATCCATTTATACAG CATCGGTTATATGAAAGGCGATCCCGGTTTTGCGCGTTACTTCGCCTATTTAAATCTGTTCATATTTTCGATGCTCAATC TGGTACTTGCAGAAAACCTAATACTTCTATTTTTAGGATGGGAAGGAGTAGGACTTTGTTCGTATTTATTGATAGGGTTT GACTATCATAAAGAAACGGCCGCCAACGCCGGGATGAAGGCGTTTATCGTAAACCGAATCGGAGATTTAGGGATGTTGCT CGGAATTGCGTTCGTGTTTTGGTACACGGGTTCCGTATCCTTTACCGTAATCGAAGAAGCAATTTTAGAAATACCATCTT TTCGTTATATACTACCGTTAGCCGCGGCTTGTTTTTTTATCGGAGCGATCGGAAAATCCGCACAACTTCCATTACACGTA TGGCTTCCGGACGCGATGGCTGGCCCAACTCCCGTTTCCGCGCTCATTCACGCGGCGACGATGGTAACGGCGGGAATCTT TTTAATCGCAAGATTAAATCCTATTTTTTTATCCGCTCCACAAGTCGGACATTGGATCGTAGTTATAGGATCGATCACCG CTTTTTTTGCAGCGACCGTAGGCTTATTTCAAAACGACATCAAAAAAGTCCTGGCCTATTCTACCGTTTCACAACTCGGA TATATGTTTGTGGCGATGGGAGCCGGAGCGTATGTCGCAGGGCTCTTTCATTTAATGACTCACGCTTTTTTTAAGGCTCT TCTATTTTTGGGGTCCGGATCGGTAATCCACGCGTTACATCACGAACAGGATCTACGTAACATGGGCGGACTTAAGAAAC AGATGAAAATAACATGGATTACTTTTTTGATTGGGTCGCTTGCAATTTCAGGAATACCACCGTTTAGCGGATTTTTTTCC AAAGATCTAATATTAGAAAAAGCTTATGCTTATGGAACCTTGTTTTACGGACTCGGAATTATAACCGCGCTTTTGACGGC GTTTTATATGTTTCGAATGACGTATCTAACGTTTTACGGAGAATCCAGAGTATCTTCCGAAAAGGCTTCGCATCTGCACG AATCCCCACTTGTGATGACGATTCCCCTTATCATTTTATCCATCGGAGCGACGGTCACCGGATTTTTGGAAGTTCCTCAT CTTTTTTACGGAGGAGTCAGAATACTTACAAGTTACTTCGGTCCGGTTTTTATCCGAGGAATTGAAATTTCGGAAAGGAT CGTAAAACAACCATTAGACGCTCGCGAGGTCGGAACAACAACCACTGTCGAGTTGAGTTTGATAGCGGTATCGATTGCAG TTGCAATTTCCGGAATATTCATCGCAAGGATGATCTTTTTAAACGGGAAAAAAGTTCCAGACTCGGAAGAATCCCATACC GGAATCAAAAGAATACTTACTAAAAAATACTACGTGGATGAGTTTTATCATAACTTCATCGTGGAACCGATCCTACTGCT CGGAAAATTTTTAGCAGATCACGTGGAAAGAAATTTCCTAGATCTAATGTTACGCGGCACGGGAAGAGTGGCGGTTGCGA TTTCTTTGGTTTTAAGAAGGGCTCAAACCGGAATCGTAGTGGACTACGCAATTTTGATTGTATTAGGAACCGTGGTCATT CTTTCCTTTTTTCTATTGAGGGGGCTATAA
Upstream 100 bases:
>100_bases GCGGCAGAGGCGGCGATCGGACTGGCCATTGTCATCGCAATCCATAGGATCAAAAAGACTAGTTATGTAGACGAAATGAA TCTGATGAAATGGTAGAAGA
Downstream 100 bases:
>100_bases CTTGGATTTCCCACCGTATATACTGAGTGTTTTTTTATTTTTACCGTTCATTGGGGTTCCACTTTTATTTTTATCCAACA AAGTAAATTGGTTAAGATTC
Product: NADH dehydrogenase I subunit L
Products: NA
Alternate protein names: NADH dehydrogenase I subunit L; NDH-1 subunit L [H]
Number of amino acids: Translated: 649; Mature: 649
Protein sequence:
>649_residues MEISVLIPTLVALPLIGFLVSGIFGKWLKGFTGIFSTATVFVSFALALLSFVDRFHPMRNGIPKIVTLFPWITTGGLNVS LAYQVDQLSLYMVLIITGIGSLIHLYSIGYMKGDPGFARYFAYLNLFIFSMLNLVLAENLILLFLGWEGVGLCSYLLIGF DYHKETAANAGMKAFIVNRIGDLGMLLGIAFVFWYTGSVSFTVIEEAILEIPSFRYILPLAAACFFIGAIGKSAQLPLHV WLPDAMAGPTPVSALIHAATMVTAGIFLIARLNPIFLSAPQVGHWIVVIGSITAFFAATVGLFQNDIKKVLAYSTVSQLG YMFVAMGAGAYVAGLFHLMTHAFFKALLFLGSGSVIHALHHEQDLRNMGGLKKQMKITWITFLIGSLAISGIPPFSGFFS KDLILEKAYAYGTLFYGLGIITALLTAFYMFRMTYLTFYGESRVSSEKASHLHESPLVMTIPLIILSIGATVTGFLEVPH LFYGGVRILTSYFGPVFIRGIEISERIVKQPLDAREVGTTTTVELSLIAVSIAVAISGIFIARMIFLNGKKVPDSEESHT GIKRILTKKYYVDEFYHNFIVEPILLLGKFLADHVERNFLDLMLRGTGRVAVAISLVLRRAQTGIVVDYAILIVLGTVVI LSFFLLRGL
Sequences:
>Translated_649_residues MEISVLIPTLVALPLIGFLVSGIFGKWLKGFTGIFSTATVFVSFALALLSFVDRFHPMRNGIPKIVTLFPWITTGGLNVS LAYQVDQLSLYMVLIITGIGSLIHLYSIGYMKGDPGFARYFAYLNLFIFSMLNLVLAENLILLFLGWEGVGLCSYLLIGF DYHKETAANAGMKAFIVNRIGDLGMLLGIAFVFWYTGSVSFTVIEEAILEIPSFRYILPLAAACFFIGAIGKSAQLPLHV WLPDAMAGPTPVSALIHAATMVTAGIFLIARLNPIFLSAPQVGHWIVVIGSITAFFAATVGLFQNDIKKVLAYSTVSQLG YMFVAMGAGAYVAGLFHLMTHAFFKALLFLGSGSVIHALHHEQDLRNMGGLKKQMKITWITFLIGSLAISGIPPFSGFFS KDLILEKAYAYGTLFYGLGIITALLTAFYMFRMTYLTFYGESRVSSEKASHLHESPLVMTIPLIILSIGATVTGFLEVPH LFYGGVRILTSYFGPVFIRGIEISERIVKQPLDAREVGTTTTVELSLIAVSIAVAISGIFIARMIFLNGKKVPDSEESHT GIKRILTKKYYVDEFYHNFIVEPILLLGKFLADHVERNFLDLMLRGTGRVAVAISLVLRRAQTGIVVDYAILIVLGTVVI LSFFLLRGL >Mature_649_residues MEISVLIPTLVALPLIGFLVSGIFGKWLKGFTGIFSTATVFVSFALALLSFVDRFHPMRNGIPKIVTLFPWITTGGLNVS LAYQVDQLSLYMVLIITGIGSLIHLYSIGYMKGDPGFARYFAYLNLFIFSMLNLVLAENLILLFLGWEGVGLCSYLLIGF DYHKETAANAGMKAFIVNRIGDLGMLLGIAFVFWYTGSVSFTVIEEAILEIPSFRYILPLAAACFFIGAIGKSAQLPLHV WLPDAMAGPTPVSALIHAATMVTAGIFLIARLNPIFLSAPQVGHWIVVIGSITAFFAATVGLFQNDIKKVLAYSTVSQLG YMFVAMGAGAYVAGLFHLMTHAFFKALLFLGSGSVIHALHHEQDLRNMGGLKKQMKITWITFLIGSLAISGIPPFSGFFS KDLILEKAYAYGTLFYGLGIITALLTAFYMFRMTYLTFYGESRVSSEKASHLHESPLVMTIPLIILSIGATVTGFLEVPH LFYGGVRILTSYFGPVFIRGIEISERIVKQPLDAREVGTTTTVELSLIAVSIAVAISGIFIARMIFLNGKKVPDSEESHT GIKRILTKKYYVDEFYHNFIVEPILLLGKFLADHVERNFLDLMLRGTGRVAVAISLVLRRAQTGIVVDYAILIVLGTVVI LSFFLLRGL
Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto
COG id: COG1009
COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the complex I subunit 5 family [H]
Homologues:
Organism=Homo sapiens, GI251831117, Length=415, Percent_Identity=41.6867469879518, Blast_Score=297, Evalue=3e-80, Organism=Escherichia coli, GI1788614, Length=601, Percent_Identity=40.432612312812, Blast_Score=392, Evalue=1e-110, Organism=Escherichia coli, GI1788829, Length=333, Percent_Identity=34.2342342342342, Blast_Score=173, Evalue=3e-44, Organism=Escherichia coli, GI1788827, Length=426, Percent_Identity=32.3943661971831, Blast_Score=152, Evalue=4e-38, Organism=Escherichia coli, GI1788831, Length=344, Percent_Identity=31.3953488372093, Blast_Score=131, Evalue=1e-31, Organism=Escherichia coli, GI1788613, Length=473, Percent_Identity=28.5412262156448, Blast_Score=111, Evalue=1e-25, Organism=Escherichia coli, GI2367154, Length=428, Percent_Identity=26.1682242990654, Blast_Score=111, Evalue=1e-25, Organism=Escherichia coli, GI145693160, Length=292, Percent_Identity=30.1369863013699, Blast_Score=72, Evalue=1e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001750 - InterPro: IPR001516 - InterPro: IPR003945 - InterPro: IPR018393 [H]
Pfam domain/function: PF00361 Oxidored_q1; PF00662 Oxidored_q1_N [H]
EC number: =1.6.99.5 [H]
Molecular weight: Translated: 71219; Mature: 71219
Theoretical pI: Translated: 9.33; Mature: 9.33
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 2.9 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 2.9 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MEISVLIPTLVALPLIGFLVSGIFGKWLKGFTGIFSTATVFVSFALALLSFVDRFHPMRN CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC GIPKIVTLFPWITTGGLNVSLAYQVDQLSLYMVLIITGIGSLIHLYSIGYMKGDPGFARY CCCHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH FAYLNLFIFSMLNLVLAENLILLFLGWEGVGLCSYLLIGFDYHKETAANAGMKAFIVNRI HHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHH GDLGMLLGIAFVFWYTGSVSFTVIEEAILEIPSFRYILPLAAACFFIGAIGKSAQLPLHV HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEE WLPDAMAGPTPVSALIHAATMVTAGIFLIARLNPIFLSAPQVGHWIVVIGSITAFFAATV ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCEEEEHHHHHHHHHHHH GLFQNDIKKVLAYSTVSQLGYMFVAMGAGAYVAGLFHLMTHAFFKALLFLGSGSVIHALH HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH HEQDLRNMGGLKKQMKITWITFLIGSLAISGIPPFSGFFSKDLILEKAYAYGTLFYGLGI HHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH ITALLTAFYMFRMTYLTFYGESRVSSEKASHLHESPLVMTIPLIILSIGATVTGFLEVPH HHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH LFYGGVRILTSYFGPVFIRGIEISERIVKQPLDAREVGTTTTVELSLIAVSIAVAISGIF HHHHHHHHHHHHHCHHEEECCHHHHHHHHCCCCHHHCCCCEEEEHHHHHHHHHHHHHHHH IARMIFLNGKKVPDSEESHTGIKRILTKKYYVDEFYHNFIVEPILLLGKFLADHVERNFL HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH DLMLRGTGRVAVAISLVLRRAQTGIVVDYAILIVLGTVVILSFFLLRGL HHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC >Mature Secondary Structure MEISVLIPTLVALPLIGFLVSGIFGKWLKGFTGIFSTATVFVSFALALLSFVDRFHPMRN CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC GIPKIVTLFPWITTGGLNVSLAYQVDQLSLYMVLIITGIGSLIHLYSIGYMKGDPGFARY CCCHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH FAYLNLFIFSMLNLVLAENLILLFLGWEGVGLCSYLLIGFDYHKETAANAGMKAFIVNRI HHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHH GDLGMLLGIAFVFWYTGSVSFTVIEEAILEIPSFRYILPLAAACFFIGAIGKSAQLPLHV HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEE WLPDAMAGPTPVSALIHAATMVTAGIFLIARLNPIFLSAPQVGHWIVVIGSITAFFAATV ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCEEEEHHHHHHHHHHHH GLFQNDIKKVLAYSTVSQLGYMFVAMGAGAYVAGLFHLMTHAFFKALLFLGSGSVIHALH HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH HEQDLRNMGGLKKQMKITWITFLIGSLAISGIPPFSGFFSKDLILEKAYAYGTLFYGLGI HHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH ITALLTAFYMFRMTYLTFYGESRVSSEKASHLHESPLVMTIPLIILSIGATVTGFLEVPH HHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH LFYGGVRILTSYFGPVFIRGIEISERIVKQPLDAREVGTTTTVELSLIAVSIAVAISGIF HHHHHHHHHHHHHCHHEEECCHHHHHHHHCCCCHHHCCCCEEEEHHHHHHHHHHHHHHHH IARMIFLNGKKVPDSEESHTGIKRILTKKYYVDEFYHNFIVEPILLLGKFLADHVERNFL HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH DLMLRGTGRVAVAISLVLRRAQTGIVVDYAILIVLGTVVILSFFLLRGL HHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA