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The map label for this gene is nuoC

Identifier: 45658577

GI number: 45658577

Start: 3339475

End: 3340011

Strand: Direct

Name: nuoC

Synonym: LIC12743

Alternate gene names: 45658577

Gene position: 3339475-3340011 (Clockwise)

Preceding gene: 45658576

Following gene: 45658578

Centisome position: 78.08

GC content: 36.13

Gene sequence:

>537_bases
ATGAAAGAAAAAGTAGAAAGTTTTCTCAAAGAAAAATTCCCTCATTTTTTAGATTTTCAGGAAGAAGTAATATCCAACGT
TCCCGTTTTTTTTCTCAAAGTGGAAGGTATAGTTCCCGTACTAACCGCTCTTAAAAACGATCCAACACTTCATTATAATT
TTCTAAATGATTTAACCGCAGTAGACTGGCTGGGTAAAAAAGAGCCTCGTTTCGAAGTCAATTATCTACTTCGTTCTGAA
AATAAAGCTTCCAGTAAAATTCGTATCAAGGTTAGACTGGAAGACGGAGAATCGGTTCCAAGTATTACTTCTGTATTTAA
AGGAGCGAACTGGCCGGAAAGAGAAGTATATGATCTTTTTGGAATCTCTTTTATCGGTCATCCTAATTTAGATCGGATTT
TAATGCCCGATAATTTTCAAGGACATCCTTTGCGGAAGGACTTTCCTTTGGAAGGTTTTGGTCAAGATTATCTGATCGAA
GACCTTTTACACATTCACGTAAACGAAGACATTACAAAAGAAGGAGGGAAGAAATAG

Upstream 100 bases:

>100_bases
TACAAACTAAATTAAAAACCCAGGGCTTGGAAGCAAGACGTCAAGAAGTAATGCAAAAGATCCAGGAACTCAACGAAAGA
AATAAGCCCCTGGTTGTGCG

Downstream 100 bases:

>100_bases
TATGATGTACGAAAAAACCGCAGAACACTTCGAACAAAAATATAAAAATCTTCCCGAAGGTCATCTACTCGTAAACTTGG
GACCGTCCCATCCGGCCACA

Product: NADH dehydrogenase subunit I C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MKEKVESFLKEKFPHFLDFQEEVISNVPVFFLKVEGIVPVLTALKNDPTLHYNFLNDLTAVDWLGKKEPRFEVNYLLRSE
NKASSKIRIKVRLEDGESVPSITSVFKGANWPEREVYDLFGISFIGHPNLDRILMPDNFQGHPLRKDFPLEGFGQDYLIE
DLLHIHVNEDITKEGGKK

Sequences:

>Translated_178_residues
MKEKVESFLKEKFPHFLDFQEEVISNVPVFFLKVEGIVPVLTALKNDPTLHYNFLNDLTAVDWLGKKEPRFEVNYLLRSE
NKASSKIRIKVRLEDGESVPSITSVFKGANWPEREVYDLFGISFIGHPNLDRILMPDNFQGHPLRKDFPLEGFGQDYLIE
DLLHIHVNEDITKEGGKK
>Mature_178_residues
MKEKVESFLKEKFPHFLDFQEEVISNVPVFFLKVEGIVPVLTALKNDPTLHYNFLNDLTAVDWLGKKEPRFEVNYLLRSE
NKASSKIRIKVRLEDGESVPSITSVFKGANWPEREVYDLFGISFIGHPNLDRILMPDNFQGHPLRKDFPLEGFGQDYLIE
DLLHIHVNEDITKEGGKK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=119, Percent_Identity=46.218487394958, Blast_Score=107, Evalue=5e-24,
Organism=Escherichia coli, GI145693162, Length=132, Percent_Identity=43.9393939393939, Blast_Score=91, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71990788, Length=166, Percent_Identity=34.9397590361446, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI32563621, Length=166, Percent_Identity=34.9397590361446, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24656494, Length=153, Percent_Identity=38.562091503268, Blast_Score=98, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 20600; Mature: 20600

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKVESFLKEKFPHFLDFQEEVISNVPVFFLKVEGIVPVLTALKNDPTLHYNFLNDLTA
CHHHHHHHHHHHCCHHCCHHHHHHCCCCEEEEEECCHHHHHHHHCCCCEEEEHHHHHHHH
VDWLGKKEPRFEVNYLLRSENKASSKIRIKVRLEDGESVPSITSVFKGANWPEREVYDLF
HHHCCCCCCCEEEEEEEECCCCCCCEEEEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHH
GISFIGHPNLDRILMPDNFQGHPLRKDFPLEGFGQDYLIEDLLHIHVNEDITKEGGKK
CEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKEKVESFLKEKFPHFLDFQEEVISNVPVFFLKVEGIVPVLTALKNDPTLHYNFLNDLTA
CHHHHHHHHHHHCCHHCCHHHHHHCCCCEEEEEECCHHHHHHHHCCCCEEEEHHHHHHHH
VDWLGKKEPRFEVNYLLRSENKASSKIRIKVRLEDGESVPSITSVFKGANWPEREVYDLF
HHHCCCCCCCEEEEEEEECCCCCCCEEEEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHH
GISFIGHPNLDRILMPDNFQGHPLRKDFPLEGFGQDYLIEDLLHIHVNEDITKEGGKK
CEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA