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The map label for this gene is nuoA

Identifier: 45658575

GI number: 45658575

Start: 3338493

End: 3338927

Strand: Direct

Name: nuoA

Synonym: LIC12741

Alternate gene names: 45658575

Gene position: 3338493-3338927 (Clockwise)

Preceding gene: 45658569

Following gene: 45658576

Centisome position: 78.05

GC content: 40.0

Gene sequence:

>435_bases
ATGAATCCGGTTCTAATAATAGCATGTGGTAAACAAAATGCCGGTCTATACGATTCAATGAATAACGCTCCTGAACATCT
TGGCCCTTTATTAATTCAATTCTTACTTGGAGTAGGTTTCTCCGCTCTGATTCTTACCCTTGCCATACTCATAGGTCCTA
AGAAGAAATCCAAACCTCAAGATACCTTCGAATGCGGGGTACAGTATTACGGAGACGCGAGAGGACTTTTTAACATCAAG
TTTTACTTAGTTGCCGTCCTTTTTATACTGTTCGACATCGAAGCGGTTTTTTTATTTCCCTACGCGGTCAATTTGATCGG
GTTTAAGAACGCTGGTCTTGGTTTTTTTCTATTCTTCGAGATGTTTGTGTTTGTTCTAACCTTAGTGGTAGGTTTATACT
ATATCTGGAAGAAAGGAGCGCTGGAATGGGACTAA

Upstream 100 bases:

>100_bases
GTTCCATTTTTAAAAAAATGAAAGGACCTGAAAGCCGAAATAAGATCTGTTTGAATTTCAGGTTGACAGGCTATATACAA
ACGAGAGTCTAATCGGTGCT

Downstream 100 bases:

>100_bases
GTGATTTGAGTAAAACCCCGGGCCAGGCACTGGGGGATATGGTTCAACTTGGAAACGTGGAATCCGTAATCCAATGGGGA
AGAAGCTATTCCCTTTGGCC

Product: NADH dehydrogenase subunit I A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1 [H]

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MNPVLIIACGKQNAGLYDSMNNAPEHLGPLLIQFLLGVGFSALILTLAILIGPKKKSKPQDTFECGVQYYGDARGLFNIK
FYLVAVLFILFDIEAVFLFPYAVNLIGFKNAGLGFFLFFEMFVFVLTLVVGLYYIWKKGALEWD

Sequences:

>Translated_144_residues
MNPVLIIACGKQNAGLYDSMNNAPEHLGPLLIQFLLGVGFSALILTLAILIGPKKKSKPQDTFECGVQYYGDARGLFNIK
FYLVAVLFILFDIEAVFLFPYAVNLIGFKNAGLGFFLFFEMFVFVLTLVVGLYYIWKKGALEWD
>Mature_144_residues
MNPVLIIACGKQNAGLYDSMNNAPEHLGPLLIQFLLGVGFSALILTLAILIGPKKKSKPQDTFECGVQYYGDARGLFNIK
FYLVAVLFILFDIEAVFLFPYAVNLIGFKNAGLGFFLFFEMFVFVLTLVVGLYYIWKKGALEWD

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788625, Length=130, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023043
- InterPro:   IPR000440 [H]

Pfam domain/function: PF00507 Oxidored_q4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 16132; Mature: 16132

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPVLIIACGKQNAGLYDSMNNAPEHLGPLLIQFLLGVGFSALILTLAILIGPKKKSKPQ
CCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCC
DTFECGVQYYGDARGLFNIKFYLVAVLFILFDIEAVFLFPYAVNLIGFKNAGLGFFLFFE
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
MFVFVLTLVVGLYYIWKKGALEWD
HHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNPVLIIACGKQNAGLYDSMNNAPEHLGPLLIQFLLGVGFSALILTLAILIGPKKKSKPQ
CCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCC
DTFECGVQYYGDARGLFNIKFYLVAVLFILFDIEAVFLFPYAVNLIGFKNAGLGFFLFFE
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
MFVFVLTLVVGLYYIWKKGALEWD
HHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA