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The map label for this gene is pdtaR [H]

Identifier: 45658464

GI number: 45658464

Start: 3177509

End: 3178888

Strand: Direct

Name: pdtaR [H]

Synonym: LIC12627

Alternate gene names: 45658464

Gene position: 3177509-3178888 (Clockwise)

Preceding gene: 45658462

Following gene: 304570502

Centisome position: 74.29

GC content: 37.39

Gene sequence:

>1380_bases
ATGGATATGCTTCAAAAACCCAAAATATTGGTGGTCGAAGACGAGATCATCGTTGCCGTAAACCTAGGACAAAAACTAAA
AAAGCTAGGTTATGAGCTTGTAGGAATCACATCATCTGGGGAAGAAGCAATCCAGAAAGCGGAAGAAAATCATCCGGATT
TAGTTCTCATGGATATAAACATAGAAGGAAATTTGGACGGAATTGAAACCGCCGAAGTACTTCGAAATCGGTTTCATACA
CCCGTTATTTATTTAACCGCATACGCAGATGAAAGCACTTTAGATAGGGCCAAAAAAACGGAACCTTTAGGGTATATCGT
AAAACCTTTTGAATCGGATCAACTCCGCTCATCCATCGAAGTCGCCCTTTATAAAAATGAAATTGAACAAAGATCAAAAC
AAACGGAAGAAAAATTAAAAGGTGCTCTCGACCAACTTGGAGCAGGAATCGTAACTACCGACGAAAACGGGCTTCTTCTT
TTTATGAATCCGGCGGCTGAAAAATTGATCGGTTGTAAATATGAAGATTATTTAGGAAAACCGATTCGACAAATTTTGTT
TTTCAGAAATGGGTCTGGCAATACGGTCGAAAACTTAGTAGAAGAAGTACTCAAATCTGGACTTCCCAAAGATAATGGAA
ATCTATTTTTAATTTCCAAAAACGGAAGTAGCCATGAAATTCAATTTCAAAGTTCTCCTATCTTTGGAGGAGAAGAAAAA
CTAACCGGAACTTTTAACATTCTTAGAACCAAAGAACAACATACAAATAACGCCGAAAAAGATACTTATCTCAAAGAAAT
TCATCATAGAATCAAAAACAATCTTACGATCATCTCCTCTATCTTTAGTCTTAGATCGGGTCAAACAACTGGAGAATCTA
ACGACGTTCTTCGAGAAAGTCAAAATCGTCTAAGAGCGGTGGCTCTTCTTCACGAAATTCTCTATGAAAGTAAAGATCTT
TCTTTGATCAGTTTTGAACTCTACGTAAAAAAACTTACAGATGCACTTTTTCAAATCTATCAAGTAAATAGAGAAAAAGT
TCGTCTGGAACTCAATATCCAAGAAGGCAAGGTAAAAGCCGAGATTGGTATGAACCTCGCTTTGATTATCAACGAACTTA
TTACAAATTCGTTAAAACACGGACTGGCGAATTCTGAATCTGGTTCGATTCGAGTTCATTTTACAAAGGAGAACGACATT
TTAGTCCTTGAAGTTTCTGACAGCGGAAACGGTCTTCCCGAAGAATCAATTCGAAAAAGAAACCCAAGTTCTCTTGGACT
ATCTCTTGTGGAATCTCTTGCAAAACAAATCGGCGGTAAAATCGATTTTATCAATCAAGAAGGCGCTTGCGTTCAGCTTC
GTTTTCCAGTTTCAGCTTAA

Upstream 100 bases:

>100_bases
TACTAAAAAGGTGAAAAAAATCCGAAATGAAAATTATACCATGACTTTTTGTACATTCCGACAAATAACTTGTTGAATTC
GGGAATATTTTTAGTAACTA

Downstream 100 bases:

>100_bases
AATAAGAATTTTCCCGTTTCAAATTTGTCCTAGTCCAAAAAGGAATATCTGTAGGTGATATATACACTTATTCCTACAAA
TGTCGTGATGATGTGTCGGT

Product: histidine kinase response regulator hybrid protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MDMLQKPKILVVEDEIIVAVNLGQKLKKLGYELVGITSSGEEAIQKAEENHPDLVLMDINIEGNLDGIETAEVLRNRFHT
PVIYLTAYADESTLDRAKKTEPLGYIVKPFESDQLRSSIEVALYKNEIEQRSKQTEEKLKGALDQLGAGIVTTDENGLLL
FMNPAAEKLIGCKYEDYLGKPIRQILFFRNGSGNTVENLVEEVLKSGLPKDNGNLFLISKNGSSHEIQFQSSPIFGGEEK
LTGTFNILRTKEQHTNNAEKDTYLKEIHHRIKNNLTIISSIFSLRSGQTTGESNDVLRESQNRLRAVALLHEILYESKDL
SLISFELYVKKLTDALFQIYQVNREKVRLELNIQEGKVKAEIGMNLALIINELITNSLKHGLANSESGSIRVHFTKENDI
LVLEVSDSGNGLPEESIRKRNPSSLGLSLVESLAKQIGGKIDFINQEGACVQLRFPVSA

Sequences:

>Translated_459_residues
MDMLQKPKILVVEDEIIVAVNLGQKLKKLGYELVGITSSGEEAIQKAEENHPDLVLMDINIEGNLDGIETAEVLRNRFHT
PVIYLTAYADESTLDRAKKTEPLGYIVKPFESDQLRSSIEVALYKNEIEQRSKQTEEKLKGALDQLGAGIVTTDENGLLL
FMNPAAEKLIGCKYEDYLGKPIRQILFFRNGSGNTVENLVEEVLKSGLPKDNGNLFLISKNGSSHEIQFQSSPIFGGEEK
LTGTFNILRTKEQHTNNAEKDTYLKEIHHRIKNNLTIISSIFSLRSGQTTGESNDVLRESQNRLRAVALLHEILYESKDL
SLISFELYVKKLTDALFQIYQVNREKVRLELNIQEGKVKAEIGMNLALIINELITNSLKHGLANSESGSIRVHFTKENDI
LVLEVSDSGNGLPEESIRKRNPSSLGLSLVESLAKQIGGKIDFINQEGACVQLRFPVSA
>Mature_459_residues
MDMLQKPKILVVEDEIIVAVNLGQKLKKLGYELVGITSSGEEAIQKAEENHPDLVLMDINIEGNLDGIETAEVLRNRFHT
PVIYLTAYADESTLDRAKKTEPLGYIVKPFESDQLRSSIEVALYKNEIEQRSKQTEEKLKGALDQLGAGIVTTDENGLLL
FMNPAAEKLIGCKYEDYLGKPIRQILFFRNGSGNTVENLVEEVLKSGLPKDNGNLFLISKNGSSHEIQFQSSPIFGGEEK
LTGTFNILRTKEQHTNNAEKDTYLKEIHHRIKNNLTIISSIFSLRSGQTTGESNDVLRESQNRLRAVALLHEILYESKDL
SLISFELYVKKLTDALFQIYQVNREKVRLELNIQEGKVKAEIGMNLALIINELITNSLKHGLANSESGSIRVHFTKENDI
LVLEVSDSGNGLPEESIRKRNPSSLGLSLVESLAKQIGGKIDFINQEGACVQLRFPVSA

Specific function: Member of the two-component regulatory system pdtaR/pdtaS [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=247, Percent_Identity=27.9352226720648, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790437, Length=116, Percent_Identity=37.0689655172414, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005561
- InterPro:   IPR011006
- InterPro:   IPR008327
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03861 ANTAR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 51248; Mature: 51248

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMLQKPKILVVEDEIIVAVNLGQKLKKLGYELVGITSSGEEAIQKAEENHPDLVLMDIN
CCCCCCCCEEEEECCEEEEECCCHHHHHCCCEEEEECCCCHHHHHHHHCCCCCEEEEEEE
IEGNLDGIETAEVLRNRFHTPVIYLTAYADESTLDRAKKTEPLGYIVKPFESDQLRSSIE
ECCCCCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHCCCCCCEEECCCCCHHHHHHHH
VALYKNEIEQRSKQTEEKLKGALDQLGAGIVTTDENGLLLFMNPAAEKLIGCKYEDYLGK
HEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCHHHHHHCCCCHHHHCC
PIRQILFFRNGSGNTVENLVEEVLKSGLPKDNGNLFLISKNGSSHEIQFQSSPIFGGEEK
HHHHHHEEECCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCC
LTGTFNILRTKEQHTNNAEKDTYLKEIHHRIKNNLTIISSIFSLRSGQTTGESNDVLRES
CCEEEEEEECCHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHH
QNRLRAVALLHEILYESKDLSLISFELYVKKLTDALFQIYQVNREKVRLELNIQEGKVKA
HHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCEEEH
EIGMNLALIINELITNSLKHGLANSESGSIRVHFTKENDILVLEVSDSGNGLPEESIRKR
HHCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHC
NPSSLGLSLVESLAKQIGGKIDFINQEGACVQLRFPVSA
CCHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEEECCCC
>Mature Secondary Structure
MDMLQKPKILVVEDEIIVAVNLGQKLKKLGYELVGITSSGEEAIQKAEENHPDLVLMDIN
CCCCCCCCEEEEECCEEEEECCCHHHHHCCCEEEEECCCCHHHHHHHHCCCCCEEEEEEE
IEGNLDGIETAEVLRNRFHTPVIYLTAYADESTLDRAKKTEPLGYIVKPFESDQLRSSIE
ECCCCCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHCCCCCCEEECCCCCHHHHHHHH
VALYKNEIEQRSKQTEEKLKGALDQLGAGIVTTDENGLLLFMNPAAEKLIGCKYEDYLGK
HEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCHHHHHHCCCCHHHHCC
PIRQILFFRNGSGNTVENLVEEVLKSGLPKDNGNLFLISKNGSSHEIQFQSSPIFGGEEK
HHHHHHEEECCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCC
LTGTFNILRTKEQHTNNAEKDTYLKEIHHRIKNNLTIISSIFSLRSGQTTGESNDVLRES
CCEEEEEEECCHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHH
QNRLRAVALLHEILYESKDLSLISFELYVKKLTDALFQIYQVNREKVRLELNIQEGKVKA
HHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCEEEH
EIGMNLALIINELITNSLKHGLANSESGSIRVHFTKENDILVLEVSDSGNGLPEESIRKR
HHCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHC
NPSSLGLSLVESLAKQIGGKIDFINQEGACVQLRFPVSA
CCHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]