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The map label for this gene is trpD

Identifier: 45658383

GI number: 45658383

Start: 3079773

End: 3080783

Strand: Reverse

Name: trpD

Synonym: LIC12541

Alternate gene names: 45658383

Gene position: 3080783-3079773 (Counterclockwise)

Preceding gene: 45658384

Following gene: 45658382

Centisome position: 72.03

GC content: 39.27

Gene sequence:

>1011_bases
ATGGAACCAAGAGCAGCCGTTCTTAAACTCATCGAACATAAACATTTAACCGCTTTAGAAGCGGAATCTTTTATGAACCA
TGTAATGAAAGGAGAGGTTTCTGAAATTTTACTTTCTTCTTTTTTGACCGCAATGCGTTTCAATGGGGAATCCGTAGAAG
AAGTGTTAGGTTGTACATTGGCGCTTCGTAAAAACGCTCTTCGACCTAAAACCGTTTTTCCATTTGATTTATTGGATACC
TGTGGAACAGGAGGAGATGGACAAGGAACGATCAATATCAGCACTCTCTCTGCGATCGTTTTAGCTTCTTTAGGGATTAA
GGTGGCTAAACATGGAAACCGATCCGTTTCTTCTCATACAGGTTCTAGCGATATATTAACTCGGTTAGGTTATCAAACCG
AGACAACTCAAGAAGAAGTGGAAGCTCATCTTGTAAATAGAGGATTTACATTTTTATTTGCTCCTATGTGGCATCCATCT
ATGAAACACGCTGGTCCGGTTCGGAAAGAACTGGGATTTAGAACCGTCTTCAATATGATTGGCCCACTTTCCAATCCGTT
TTCTCCTCAGTTTCAAATTATAGGTGTGTATCAACCAGAATTGATGGAACTGTTTATCAAAGTATTACAATCTTTAGGTT
TGAAGAGGGCTTTGGTATGTCATTCGAGGGATGGTTTGGACGAATTTTCAATCTTTCAGATTACGGATTATACTTTTTTA
GAAAATGGTGTAATTAGCCGCCATTCGTTTGATCCTAAAATTTTAGGACTTTCTTCTTTAAACAAAGAAGAAGTATATGC
TTCTTCCAGCGACCATGCAGAGGTTTTGGCGAGAAAGGTTTTGAATTCGGAATCGATTGCGGGGACACACGCGGTGGCAT
TGAATGCGGGAGCTGGACTTTTTGTAATGGGGAAGATAGATACAATTGAACAAGGGTATCAAATCGCCAAAGAGGCCATT
CTTTCCGGAAAAACAAAAAAGTATTTCGAAGATTTAATTTCCAAAGAGTAA

Upstream 100 bases:

>100_bases
TTGGTCACTACCACAATTACTGTGATTTCCGGAATCCGTTATTTAGTTTCCAATAGTAAAGTTCTTTATCCTTCTAATCT
CAAAGGGATGTTTCAAAAAA

Downstream 100 bases:

>100_bases
ACGAGAAAAATACTGGTAAGAATTTGACGAAAAGAACCGAACAGGAAAGTAAACGATGACATTTGATATTTTACTACAAT
TGGCTCAGGCCGCCGGAGAA

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MEPRAAVLKLIEHKHLTALEAESFMNHVMKGEVSEILLSSFLTAMRFNGESVEEVLGCTLALRKNALRPKTVFPFDLLDT
CGTGGDGQGTINISTLSAIVLASLGIKVAKHGNRSVSSHTGSSDILTRLGYQTETTQEEVEAHLVNRGFTFLFAPMWHPS
MKHAGPVRKELGFRTVFNMIGPLSNPFSPQFQIIGVYQPELMELFIKVLQSLGLKRALVCHSRDGLDEFSIFQITDYTFL
ENGVISRHSFDPKILGLSSLNKEEVYASSSDHAEVLARKVLNSESIAGTHAVALNAGAGLFVMGKIDTIEQGYQIAKEAI
LSGKTKKYFEDLISKE

Sequences:

>Translated_336_residues
MEPRAAVLKLIEHKHLTALEAESFMNHVMKGEVSEILLSSFLTAMRFNGESVEEVLGCTLALRKNALRPKTVFPFDLLDT
CGTGGDGQGTINISTLSAIVLASLGIKVAKHGNRSVSSHTGSSDILTRLGYQTETTQEEVEAHLVNRGFTFLFAPMWHPS
MKHAGPVRKELGFRTVFNMIGPLSNPFSPQFQIIGVYQPELMELFIKVLQSLGLKRALVCHSRDGLDEFSIFQITDYTFL
ENGVISRHSFDPKILGLSSLNKEEVYASSSDHAEVLARKVLNSESIAGTHAVALNAGAGLFVMGKIDTIEQGYQIAKEAI
LSGKTKKYFEDLISKE
>Mature_336_residues
MEPRAAVLKLIEHKHLTALEAESFMNHVMKGEVSEILLSSFLTAMRFNGESVEEVLGCTLALRKNALRPKTVFPFDLLDT
CGTGGDGQGTINISTLSAIVLASLGIKVAKHGNRSVSSHTGSSDILTRLGYQTETTQEEVEAHLVNRGFTFLFAPMWHPS
MKHAGPVRKELGFRTVFNMIGPLSNPFSPQFQIIGVYQPELMELFIKVLQSLGLKRALVCHSRDGLDEFSIFQITDYTFL
ENGVISRHSFDPKILGLSSLNKEEVYASSSDHAEVLARKVLNSESIAGTHAVALNAGAGLFVMGKIDTIEQGYQIAKEAI
LSGKTKKYFEDLISKE

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=274, Percent_Identity=39.4160583941606, Blast_Score=173, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6320561, Length=311, Percent_Identity=28.6173633440514, Blast_Score=106, Evalue=6e-24,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_LEPIC (Q72PD0)

Other databases:

- EMBL:   AE016823
- RefSeq:   YP_002469.1
- ProteinModelPortal:   Q72PD0
- GeneID:   2771367
- GenomeReviews:   AE016823_GR
- KEGG:   lic:LIC12541
- NMPDR:   fig|267671.1.peg.2469
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- ProtClustDB:   PRK00188
- BioCyc:   LINT267671:LIC_12541-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 36903; Mature: 36903

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPRAAVLKLIEHKHLTALEAESFMNHVMKGEVSEILLSSFLTAMRFNGESVEEVLGCTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ALRKNALRPKTVFPFDLLDTCGTGGDGQGTINISTLSAIVLASLGIKVAKHGNRSVSSHT
HHHHCCCCCCCCCCHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GSSDILTRLGYQTETTQEEVEAHLVNRGFTFLFAPMWHPSMKHAGPVRKELGFRTVFNMI
CCHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHCCCHHHHHHHHHHHHHH
GPLSNPFSPQFQIIGVYQPELMELFIKVLQSLGLKRALVCHSRDGLDEFSIFQITDYTFL
CCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCHHEEHHCCCCCCCCCEEEEEECHHHH
ENGVISRHSFDPKILGLSSLNKEEVYASSSDHAEVLARKVLNSESIAGTHAVALNAGAGL
HCCCCCCCCCCCCEEECCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCE
FVMGKIDTIEQGYQIAKEAILSGKTKKYFEDLISKE
EEEECHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure
MEPRAAVLKLIEHKHLTALEAESFMNHVMKGEVSEILLSSFLTAMRFNGESVEEVLGCTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ALRKNALRPKTVFPFDLLDTCGTGGDGQGTINISTLSAIVLASLGIKVAKHGNRSVSSHT
HHHHCCCCCCCCCCHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GSSDILTRLGYQTETTQEEVEAHLVNRGFTFLFAPMWHPSMKHAGPVRKELGFRTVFNMI
CCHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHCCCHHHHHHHHHHHHHH
GPLSNPFSPQFQIIGVYQPELMELFIKVLQSLGLKRALVCHSRDGLDEFSIFQITDYTFL
CCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCHHEEHHCCCCCCCCCEEEEEECHHHH
ENGVISRHSFDPKILGLSSLNKEEVYASSSDHAEVLARKVLNSESIAGTHAVALNAGAGL
HCCCCCCCCCCCCEEECCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCE
FVMGKIDTIEQGYQIAKEAILSGKTKKYFEDLISKE
EEEECHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA