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The map label for this gene is cysW

Identifier: 45658369

GI number: 45658369

Start: 3063987

End: 3064826

Strand: Reverse

Name: cysW

Synonym: LIC12527

Alternate gene names: 45658369

Gene position: 3064826-3063987 (Counterclockwise)

Preceding gene: 45658370

Following gene: 45658368

Centisome position: 71.66

GC content: 39.52

Gene sequence:

>840_bases
ATGAAACAAGAATCGTTAATCGTTAGAAGTTTTCTTATCGGTGTCGTTTTTTTTCTCACCGTTTTGATTTTGATTCTTCC
TATTTATACCGTCTTTCAAGAAGCATTCTCCAAAGGTTTTGGTGCTTACTGGGAAGGGATTCGGGAACCCGATACCGTTT
CCGCTTTCAAATTGACTCTTTTAGTAATCGGAATCGCCGTTCCTTTGAATACTATTTTCGGAATTTTTGCTGCTTTCTCA
TTGACTCGTTTTGAATTTCCGGGCAAAAGCTGGATACTCACGATCATAGATTCTCCATTTTCGGTTTCACCTGTGATCTC
CGGTTTGATTTTTATTCTTCTTTTTGGAAGACAGGGGTGGTTTGGTCCTTGGTTAGAAAAATTAGACTTCAAAATTGTAT
TCAACACTCCAGGGCTTGTGATCGCTACGGTTTTTATTACTCTTCCTTTTGTGGCAAGAGAACTGATTCCTGTATTGGAC
GCTACCGGGATGGAAGAGGAAGAAGCGGGACTTCTTTTAGGCGCTTCTCCGATCAAAGTGTTTTTGAAAATTGTTGCACC
AGGTATCAAATACGGACTGTTATACGGAATTATACTTTGTAACGCGAGAGCTATGGGAGAATTTGGTGCAGTCTCTGTTC
TTTCCGGACATATCCGAGGCCAAACGAATACGTTGCCGTTACAAATTGAAGTACTTTATAATGAATATAATTCTGTGGCA
GCTTTCTCGGCGGCTTCTCTTCTTGTATTTTTATCCTTAATCACTCTCGTCGCAAAACAGATCTTGGAAAGAAAAATCAA
AATCGTAAAAAAAGAGGAATTTCTCCAAGAGGAGGTATAA

Upstream 100 bases:

>100_bases
ACGAAGAAGCGACCGGAATTGCGTTTATTATGCTTGTAATTTCATTTAGTATATTATTATGTATTAATGTTATTCAGAAC
ATCGCTGCTAGGAAAAGCGA

Downstream 100 bases:

>100_bases
CGTGGGAATTGAAGTTAAGAATCTTGTAAAACGTTTTGGAAATTTTACTGCCATCGACGATCTTTCTTTAGATGTTCCTT
CTGGAGAGTTAGTCGCTCTT

Product: sulfate ABC transport system permease protein

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MKQESLIVRSFLIGVVFFLTVLILILPIYTVFQEAFSKGFGAYWEGIREPDTVSAFKLTLLVIGIAVPLNTIFGIFAAFS
LTRFEFPGKSWILTIIDSPFSVSPVISGLIFILLFGRQGWFGPWLEKLDFKIVFNTPGLVIATVFITLPFVARELIPVLD
ATGMEEEEAGLLLGASPIKVFLKIVAPGIKYGLLYGIILCNARAMGEFGAVSVLSGHIRGQTNTLPLQIEVLYNEYNSVA
AFSAASLLVFLSLITLVAKQILERKIKIVKKEEFLQEEV

Sequences:

>Translated_279_residues
MKQESLIVRSFLIGVVFFLTVLILILPIYTVFQEAFSKGFGAYWEGIREPDTVSAFKLTLLVIGIAVPLNTIFGIFAAFS
LTRFEFPGKSWILTIIDSPFSVSPVISGLIFILLFGRQGWFGPWLEKLDFKIVFNTPGLVIATVFITLPFVARELIPVLD
ATGMEEEEAGLLLGASPIKVFLKIVAPGIKYGLLYGIILCNARAMGEFGAVSVLSGHIRGQTNTLPLQIEVLYNEYNSVA
AFSAASLLVFLSLITLVAKQILERKIKIVKKEEFLQEEV
>Mature_279_residues
MKQESLIVRSFLIGVVFFLTVLILILPIYTVFQEAFSKGFGAYWEGIREPDTVSAFKLTLLVIGIAVPLNTIFGIFAAFS
LTRFEFPGKSWILTIIDSPFSVSPVISGLIFILLFGRQGWFGPWLEKLDFKIVFNTPGLVIATVFITLPFVARELIPVLD
ATGMEEEEAGLLLGASPIKVFLKIVAPGIKYGLLYGIILCNARAMGEFGAVSVLSGHIRGQTNTLPLQIEVLYNEYNSVA
AFSAASLLVFLSLITLVAKQILERKIKIVKKEEFLQEEV

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=270, Percent_Identity=45.9259259259259, Blast_Score=263, Evalue=9e-72,
Organism=Escherichia coli, GI1788764, Length=209, Percent_Identity=37.799043062201, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1786980, Length=212, Percent_Identity=30.6603773584906, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30829; Mature: 30829

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQESLIVRSFLIGVVFFLTVLILILPIYTVFQEAFSKGFGAYWEGIREPDTVSAFKLTL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHH
LVIGIAVPLNTIFGIFAAFSLTRFEFPGKSWILTIIDSPFSVSPVISGLIFILLFGRQGW
HHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCC
FGPWLEKLDFKIVFNTPGLVIATVFITLPFVARELIPVLDATGMEEEEAGLLLGASPIKV
CCHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCEEECCHHHHH
FLKIVAPGIKYGLLYGIILCNARAMGEFGAVSVLSGHIRGQTNTLPLQIEVLYNEYNSVA
HHHHHCCHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHH
AFSAASLLVFLSLITLVAKQILERKIKIVKKEEFLQEEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKQESLIVRSFLIGVVFFLTVLILILPIYTVFQEAFSKGFGAYWEGIREPDTVSAFKLTL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHH
LVIGIAVPLNTIFGIFAAFSLTRFEFPGKSWILTIIDSPFSVSPVISGLIFILLFGRQGW
HHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCC
FGPWLEKLDFKIVFNTPGLVIATVFITLPFVARELIPVLDATGMEEEEAGLLLGASPIKV
CCHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCEEECCHHHHH
FLKIVAPGIKYGLLYGIILCNARAMGEFGAVSVLSGHIRGQTNTLPLQIEVLYNEYNSVA
HHHHHCCHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHH
AFSAASLLVFLSLITLVAKQILERKIKIVKKEEFLQEEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]