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The map label for this gene is infC

Identifier: 45658305

GI number: 45658305

Start: 2979483

End: 2980022

Strand: Reverse

Name: infC

Synonym: LIC12463

Alternate gene names: 45658305

Gene position: 2980022-2979483 (Counterclockwise)

Preceding gene: 45658307

Following gene: 45658304

Centisome position: 69.67

GC content: 38.52

Gene sequence:

>540_bases
ATGCAGAGGAAACCGAGTCAAAAATCAGCAACCGATAAGCTTTTTAATCATAGAGTCAATGAGAAAATAACAGGCGTTTC
CAGGGTTCGCTTAGTGTCGGATGACGGCGTAGCGATCGTATCTTTTGAAGAAGCACTCAGAAAAGCAAAAGAGGAAAATT
TAGATCTAGTAGAAGTATCAGCGGATCAGGAACTTCACGTTTGTAAGATTATAGACTACGGAAAGTATAAATTCGAGTTA
CTTAAAAAGAGTAAAGAAGCAAAGAAAAAACAACACGTAATCAATGTAAAAGAAATTAAGATTCGCCCTCGAATTGAAAG
CCATGATTACGAAATTAAAAAGAAACACGCGCAGGAGTTTCTGGGAAAAGGAGACAAAGTAAAAGTCAGTCTCCGGTTTC
GAGGTAGAGAAATGATGCATTCTGACCTCGGAATGAAAGTAGTTTATAGAATGATAGAAGACCTGAAAGAACACGGAACC
GCCGAAAGGGATCCGATTCAGGACGGAAAACAGATCGTAGTAATCATTAATCCGAAATAA

Upstream 100 bases:

>100_bases
AAATCGACTTGCAATAAAGCTTCCTTTCACCGAAATGGAGTCAAAAATCGCTTGAAAACGCGCTTAAGGATAAAACCTTG
GAAATCTAGCCGGAGAATGA

Downstream 100 bases:

>100_bases
TTTCCGAAAAAAGGAATTCAAAGGTAGATAAGATGCCAAAGTTGAAAACGAACAGAGCCGCTGCAAAACGTTTCAAGTTC
ACAAAAAACAACAAAATCAA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MQRKPSQKSATDKLFNHRVNEKITGVSRVRLVSDDGVAIVSFEEALRKAKEENLDLVEVSADQELHVCKIIDYGKYKFEL
LKKSKEAKKKQHVINVKEIKIRPRIESHDYEIKKKHAQEFLGKGDKVKVSLRFRGREMMHSDLGMKVVYRMIEDLKEHGT
AERDPIQDGKQIVVIINPK

Sequences:

>Translated_179_residues
MQRKPSQKSATDKLFNHRVNEKITGVSRVRLVSDDGVAIVSFEEALRKAKEENLDLVEVSADQELHVCKIIDYGKYKFEL
LKKSKEAKKKQHVINVKEIKIRPRIESHDYEIKKKHAQEFLGKGDKVKVSLRFRGREMMHSDLGMKVVYRMIEDLKEHGT
AERDPIQDGKQIVVIINPK
>Mature_179_residues
MQRKPSQKSATDKLFNHRVNEKITGVSRVRLVSDDGVAIVSFEEALRKAKEENLDLVEVSADQELHVCKIIDYGKYKFEL
LKKSKEAKKKQHVINVKEIKIRPRIESHDYEIKKKHAQEFLGKGDKVKVSLRFRGREMMHSDLGMKVVYRMIEDLKEHGT
AERDPIQDGKQIVVIINPK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=166, Percent_Identity=46.9879518072289, Blast_Score=129, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 20776; Mature: 20776

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRKPSQKSATDKLFNHRVNEKITGVSRVRLVSDDGVAIVSFEEALRKAKEENLDLVEVS
CCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEHHHHHHHHHHCCCCEEEEC
ADQELHVCKIIDYGKYKFELLKKSKEAKKKQHVINVKEIKIRPRIESHDYEIKKKHAQEF
CCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHH
LGKGDKVKVSLRFRGREMMHSDLGMKVVYRMIEDLKEHGTAERDPIQDGKQIVVIINPK
HCCCCEEEEEEEECCHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCC
>Mature Secondary Structure
MQRKPSQKSATDKLFNHRVNEKITGVSRVRLVSDDGVAIVSFEEALRKAKEENLDLVEVS
CCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEHHHHHHHHHHCCCCEEEEC
ADQELHVCKIIDYGKYKFELLKKSKEAKKKQHVINVKEIKIRPRIESHDYEIKKKHAQEF
CCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHH
LGKGDKVKVSLRFRGREMMHSDLGMKVVYRMIEDLKEHGTAERDPIQDGKQIVVIINPK
HCCCCEEEEEEEECCHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA