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The map label for this gene is prmA

Identifier: 45658193

GI number: 45658193

Start: 2841280

End: 2842182

Strand: Reverse

Name: prmA

Synonym: LIC12347

Alternate gene names: 45658193

Gene position: 2842182-2841280 (Counterclockwise)

Preceding gene: 45658194

Following gene: 45658192

Centisome position: 66.45

GC content: 37.98

Gene sequence:

>903_bases
TTGAGATATAGAGAAATCATATTAAGTATTCCTAAAGAGATTGCAGAAAATTTTACCTCTTTTTTGGATGAAGTAGGAGT
TGTAGGATATTATGAAATCCTATTTGATAGGGAAGTTCCACGCGCTCCTGATGAAGAAATTATTTCAGACGATACTAAAT
TCCGAGTTTATCTCGCGGAAGAAGATAAAGAGAACGAGACCAAAATTCTAATTTTTTTAAAAGCGACCGCCGGAGAGTCT
TTCTTTTTAGAATCCAGATGGATTGAAACGAAAGAATACGAAGAAGCTTATAAAGAATTTTATAAACCCTTTATCATAGG
TTCTTATAGGGTGATTCCTACTTGGGAAAAAGATACTGCGTTAGGCACAACTCCGGAAGGAATTTTTCCGTTGCTTGTCA
ATCCTGGACTTGCATTTGGAACTGGACATCACGAGACCACACGTCTTGTTTTAGGTAGAATGGGGGATTTAAATCTTTCC
GCTAAAAGGATCGCTGACGTGGGAACTGGTTCCGGGATTTTAAGCCTTGCCGCCGCAAAATCTGGAGCTTCCCTAATTTT
AGCGATAGACGTGGATCCAAACAGTGTAAGGTCTGCTTCTTTCAATCGGGACGAAAACGAAATTTCTTCGGAAGTTTTGG
TCGTGGAAGAGGGTGGTTTTGATCATAAAAAAATTCAAGAACAAACTTGGGATTTATTGATAGCCAATATCACGTTTGCA
GTATTAAAAGCGAATATTCAGAAAATTGCATCTATTAAAACAGATCATTTTCTATTCAGCGGAGTGATCACCGAACGTAA
GGAAGAATTTTTAGAACTTCTAAAAAACACCGTTGGTGGAGAAGGTGTTTTTTTTCGGGAAGATACCGGTTGGGAATTGA
TCGAATGGAAAAGAAAAGGATAA

Upstream 100 bases:

>100_bases
TTGGAATCTGGGTTTGGATCGTAAAAGATTTTCGTACTTTCATACTTGAAAATGAAAACTTAAATGACGCGCCGGTGGAT
GCGGAAATTCTGGACGAGTC

Downstream 100 bases:

>100_bases
ATCAATGAAACACTATGACGTATTTGGAGTTGGGAACGCGCTCGTGGATATTTTAGTCCCGACTGAAAACGTATTTATCA
AACGTTTGGGATTTGAAAAA

Product: ribosomal protein l11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MRYREIILSIPKEIAENFTSFLDEVGVVGYYEILFDREVPRAPDEEIISDDTKFRVYLAEEDKENETKILIFLKATAGES
FFLESRWIETKEYEEAYKEFYKPFIIGSYRVIPTWEKDTALGTTPEGIFPLLVNPGLAFGTGHHETTRLVLGRMGDLNLS
AKRIADVGTGSGILSLAAAKSGASLILAIDVDPNSVRSASFNRDENEISSEVLVVEEGGFDHKKIQEQTWDLLIANITFA
VLKANIQKIASIKTDHFLFSGVITERKEEFLELLKNTVGGEGVFFREDTGWELIEWKRKG

Sequences:

>Translated_300_residues
MRYREIILSIPKEIAENFTSFLDEVGVVGYYEILFDREVPRAPDEEIISDDTKFRVYLAEEDKENETKILIFLKATAGES
FFLESRWIETKEYEEAYKEFYKPFIIGSYRVIPTWEKDTALGTTPEGIFPLLVNPGLAFGTGHHETTRLVLGRMGDLNLS
AKRIADVGTGSGILSLAAAKSGASLILAIDVDPNSVRSASFNRDENEISSEVLVVEEGGFDHKKIQEQTWDLLIANITFA
VLKANIQKIASIKTDHFLFSGVITERKEEFLELLKNTVGGEGVFFREDTGWELIEWKRKG
>Mature_300_residues
MRYREIILSIPKEIAENFTSFLDEVGVVGYYEILFDREVPRAPDEEIISDDTKFRVYLAEEDKENETKILIFLKATAGES
FFLESRWIETKEYEEAYKEFYKPFIIGSYRVIPTWEKDTALGTTPEGIFPLLVNPGLAFGTGHHETTRLVLGRMGDLNLS
AKRIADVGTGSGILSLAAAKSGASLILAIDVDPNSVRSASFNRDENEISSEVLVVEEGGFDHKKIQEQTWDLLIANITFA
VLKANIQKIASIKTDHFLFSGVITERKEEFLELLKNTVGGEGVFFREDTGWELIEWKRKG

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=247, Percent_Identity=27.5303643724696, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_LEPIC (Q72PX0)

Other databases:

- EMBL:   AE016823
- RefSeq:   YP_002279.1
- ProteinModelPortal:   Q72PX0
- SMR:   Q72PX0
- GeneID:   2769652
- GenomeReviews:   AE016823_GR
- KEGG:   lic:LIC12347
- HOGENOM:   HBG527716
- OMA:   MEVAKEN
- ProtClustDB:   CLSK573891
- BioCyc:   LINT267671:LIC_12347-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 33888; Mature: 33888

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYREIILSIPKEIAENFTSFLDEVGVVGYYEILFDREVPRAPDEEIISDDTKFRVYLAE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHCCCCEEEEEEEC
EDKENETKILIFLKATAGESFFLESRWIETKEYEEAYKEFYKPFIIGSYRVIPTWEKDTA
CCCCCCEEEEEEEEECCCCEEEEHHHCCCHHHHHHHHHHHCCCEEEECEEEEECCCCCCC
LGTTPEGIFPLLVNPGLAFGTGHHETTRLVLGRMGDLNLSAKRIADVGTGSGILSLAAAK
CCCCCCCCEEEEECCCCEECCCCCHHHHHHHHCCCCCCCCHHHHHCCCCCCCCEEEEECC
SGASLILAIDVDPNSVRSASFNRDENEISSEVLVVEEGGFDHKKIQEQTWDLLIANITFA
CCCEEEEEEECCCCCCCCCCCCCCHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
VLKANIQKIASIKTDHFLFSGVITERKEEFLELLKNTVGGEGVFFREDTGWELIEWKRKG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCC
>Mature Secondary Structure
MRYREIILSIPKEIAENFTSFLDEVGVVGYYEILFDREVPRAPDEEIISDDTKFRVYLAE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHCCCCEEEEEEEC
EDKENETKILIFLKATAGESFFLESRWIETKEYEEAYKEFYKPFIIGSYRVIPTWEKDTA
CCCCCCEEEEEEEEECCCCEEEEHHHCCCHHHHHHHHHHHCCCEEEECEEEEECCCCCCC
LGTTPEGIFPLLVNPGLAFGTGHHETTRLVLGRMGDLNLSAKRIADVGTGSGILSLAAAK
CCCCCCCCEEEEECCCCEECCCCCHHHHHHHHCCCCCCCCHHHHHCCCCCCCCEEEEECC
SGASLILAIDVDPNSVRSASFNRDENEISSEVLVVEEGGFDHKKIQEQTWDLLIANITFA
CCCEEEEEEECCCCCCCCCCCCCCHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
VLKANIQKIASIKTDHFLFSGVITERKEEFLELLKNTVGGEGVFFREDTGWELIEWKRKG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA