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The map label for this gene is ydjH [C]

Identifier: 45658192

GI number: 45658192

Start: 2840289

End: 2841275

Strand: Reverse

Name: ydjH [C]

Synonym: LIC12346

Alternate gene names: 45658192

Gene position: 2841275-2840289 (Counterclockwise)

Preceding gene: 45658193

Following gene: 45658186

Centisome position: 66.43

GC content: 40.53

Gene sequence:

>987_bases
ATGAAACACTATGACGTATTTGGAGTTGGGAACGCGCTCGTGGATATTTTAGTCCCGACTGAAAACGTATTTATCAAACG
TTTGGGATTTGAAAAAGGAATTATGACTTTGGTAGATTCCGAAAAACAAGCCGAAGTTTTAACCGCCCTGGAAGGAAGTA
AAAAGGAACTTCGTTCCGGAGGAAGCGCGGCAAACACTATGATCGCTCTTGCAAATTCGGGAGGAACCGGAACTTATACT
GGGAAGGTTTCTAAGGATACTTACGGAGAGTTTTATAAAAAGGACATGGAGAATGCTGGAATTCTTTTTGAAGTGGCCCC
CGAAGATAAGGGGCATACCGGGACTTGTGTTGTATTGACTACACCGGACGCAGAAAGAACGATGCTTACTCATTTAGGAA
TTTCAATTACATTACAAAAATCAGATGTAGATTTGGAAAAACTAAAATCTTCTAGTATTTCTTATATCGAAGGTTATCTT
TGGGATGGTCAAGGAACGAAAGAGGCTTCACTTTTAACCATGGAGGAATCCAAGAAAAATGGTGTAAAAGTAGCTTATAC
ATATAGTGATCCGTTTTGTGTAAATCGTTCCAGAGAGGACTTTATTCGTTTAACAAAAGAATATTTTGATATCGTTTTTT
GTAATACGGAAGAGGCGAAGGCTCTTTCTCAAAGAGAAGATAAGTTGGAAGCTCTTAAGTTTATTTCTGGCCTTTCTGCT
CTTGTGTTTATGACTGATTCCGCAAACGGAGCTTACTTTGCAGAGAATGGAAAAATTTCTCACGTAGATGGGTTTCCAGT
GAAACCGATCGATACAACGGGCGCGGGGGATTGTTTTGCGGCGGGTGTTCTTTATGGAATCACTCACGGTTTTAGCTTGG
AGAAATCTACTCGTTGGGGAAACTACGTCGCTTCTAGGATTGTACAAGAAGTTGGTCCTAGACTAGGAATTAAATTGATG
GGGCGCCAGGACGAAATTTTAAAGTAG

Upstream 100 bases:

>100_bases
TTTTTAGAACTTCTAAAAAACACCGTTGGTGGAGAAGGTGTTTTTTTTCGGGAAGATACCGGTTGGGAATTGATCGAATG
GAAAAGAAAAGGATAAATCA

Downstream 100 bases:

>100_bases
TCTTTTAACTTGCCGTTTTTCTAATGTAATATGAGTGAATGGAGCTATGGTGGTTGATCGGGTTTTTAGCTCTAGTCAAG
TTAATAGAGTTGTTGAAAAA

Product: ribokinase

Products: ADP; D-ribose 5-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MKHYDVFGVGNALVDILVPTENVFIKRLGFEKGIMTLVDSEKQAEVLTALEGSKKELRSGGSAANTMIALANSGGTGTYT
GKVSKDTYGEFYKKDMENAGILFEVAPEDKGHTGTCVVLTTPDAERTMLTHLGISITLQKSDVDLEKLKSSSISYIEGYL
WDGQGTKEASLLTMEESKKNGVKVAYTYSDPFCVNRSREDFIRLTKEYFDIVFCNTEEAKALSQREDKLEALKFISGLSA
LVFMTDSANGAYFAENGKISHVDGFPVKPIDTTGAGDCFAAGVLYGITHGFSLEKSTRWGNYVASRIVQEVGPRLGIKLM
GRQDEILK

Sequences:

>Translated_328_residues
MKHYDVFGVGNALVDILVPTENVFIKRLGFEKGIMTLVDSEKQAEVLTALEGSKKELRSGGSAANTMIALANSGGTGTYT
GKVSKDTYGEFYKKDMENAGILFEVAPEDKGHTGTCVVLTTPDAERTMLTHLGISITLQKSDVDLEKLKSSSISYIEGYL
WDGQGTKEASLLTMEESKKNGVKVAYTYSDPFCVNRSREDFIRLTKEYFDIVFCNTEEAKALSQREDKLEALKFISGLSA
LVFMTDSANGAYFAENGKISHVDGFPVKPIDTTGAGDCFAAGVLYGITHGFSLEKSTRWGNYVASRIVQEVGPRLGIKLM
GRQDEILK
>Mature_328_residues
MKHYDVFGVGNALVDILVPTENVFIKRLGFEKGIMTLVDSEKQAEVLTALEGSKKELRSGGSAANTMIALANSGGTGTYT
GKVSKDTYGEFYKKDMENAGILFEVAPEDKGHTGTCVVLTTPDAERTMLTHLGISITLQKSDVDLEKLKSSSISYIEGYL
WDGQGTKEASLLTMEESKKNGVKVAYTYSDPFCVNRSREDFIRLTKEYFDIVFCNTEEAKALSQREDKLEALKFISGLSA
LVFMTDSANGAYFAENGKISHVDGFPVKPIDTTGAGDCFAAGVLYGITHGFSLEKSTRWGNYVASRIVQEVGPRLGIKLM
GRQDEILK

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI32484973, Length=332, Percent_Identity=24.6987951807229, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI32484975, Length=332, Percent_Identity=24.6987951807229, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI5670342, Length=287, Percent_Identity=23.6933797909408, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI87081971, Length=332, Percent_Identity=25.9036144578313, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17541820, Length=332, Percent_Identity=24.6987951807229, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322565, Length=339, Percent_Identity=25.9587020648968, Blast_Score=86, Evalue=8e-18,
Organism=Drosophila melanogaster, GI21355521, Length=340, Percent_Identity=26.1764705882353, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: 2.7.1.15

Molecular weight: Translated: 35864; Mature: 35864

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHYDVFGVGNALVDILVPTENVFIKRLGFEKGIMTLVDSEKQAEVLTALEGSKKELRSG
CCCEEEEECCCEEEEEEECCCHHHHHHCCCCCCCCEEECCCHHHHHHHHHCCCHHHHHCC
GSAANTMIALANSGGTGTYTGKVSKDTYGEFYKKDMENAGILFEVAPEDKGHTGTCVVLT
CCCCEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEE
TPDAERTMLTHLGISITLQKSDVDLEKLKSSSISYIEGYLWDGQGTKEASLLTMEESKKN
CCCCHHHHHHHCCEEEEEECCCCCHHHHHCCCCCEEEEEEECCCCCCCEEEEEEECCCCC
GVKVAYTYSDPFCVNRSREDFIRLTKEYFDIVFCNTEEAKALSQREDKLEALKFISGLSA
CEEEEEEECCCEEECCCHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHCCEE
LVFMTDSANGAYFAENGKISHVDGFPVKPIDTTGAGDCFAAGVLYGITHGFSLEKSTRWG
EEEEEECCCCCEEECCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHH
NYVASRIVQEVGPRLGIKLMGRQDEILK
HHHHHHHHHHHCCCCCEEEECCCHHCCC
>Mature Secondary Structure
MKHYDVFGVGNALVDILVPTENVFIKRLGFEKGIMTLVDSEKQAEVLTALEGSKKELRSG
CCCEEEEECCCEEEEEEECCCHHHHHHCCCCCCCCEEECCCHHHHHHHHHCCCHHHHHCC
GSAANTMIALANSGGTGTYTGKVSKDTYGEFYKKDMENAGILFEVAPEDKGHTGTCVVLT
CCCCEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEE
TPDAERTMLTHLGISITLQKSDVDLEKLKSSSISYIEGYLWDGQGTKEASLLTMEESKKN
CCCCHHHHHHHCCEEEEEECCCCCHHHHHCCCCCEEEEEEECCCCCCCEEEEEEECCCCC
GVKVAYTYSDPFCVNRSREDFIRLTKEYFDIVFCNTEEAKALSQREDKLEALKFISGLSA
CEEEEEEECCCEEECCCHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHCCEE
LVFMTDSANGAYFAENGKISHVDGFPVKPIDTTGAGDCFAAGVLYGITHGFSLEKSTRWG
EEEEEECCCCCEEECCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHH
NYVASRIVQEVGPRLGIKLMGRQDEILK
HHHHHHHHHHHCCCCCEEEECCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-ribose

Specific reaction: ATP + D-ribose = ADP + D-ribose 5-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]