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The map label for this gene is glcK

Identifier: 45658160

GI number: 45658160

Start: 2787547

End: 2788443

Strand: Direct

Name: glcK

Synonym: LIC12312

Alternate gene names: 45658160

Gene position: 2787547-2788443 (Clockwise)

Preceding gene: 45658159

Following gene: 45658161

Centisome position: 65.17

GC content: 39.8

Gene sequence:

>897_bases
ATGAAATCCTTTCTTGGAATCGATATAGGTGCAGGAAGTATCAAAGCAAGTCTCATCGATTCCAACGGAAACGTACTGAA
AAGTTCTTTCCGTAAAACCGGCGCGGAAACAAACGAAAAACAATTCCTAGATTCTATTTGTGACATCGTATCAGAAATGA
AAAACTCTTCTTTGACGGCGGTGGGCATAGGAAGCCCAGGGCCAATCGATTCTGAAAACGGAATTTTGATCGAGTCCGCT
AATCTTCCTCTTTTAAAAAATGTGACGTTAGTCTCTCATTTAAAAGAAAAATTTTCTATTCCAGTATATTATAATAATGA
TGCAAACCTTGCTGCGTTGGGAGAATACCATTTCGGTTTAGGAAAAGGATCGCCTAATTTGGTAATTTTAACCTTAGGAA
CCGGATTAGGAGGTGGTTGGGTATATCAAGGAAAACTTTTTAACGGTTACAAAGGAAGTGGAATGGAAGCGGGACACGTT
ACGTATCTTCCAAACGGCTCTCTATGCGGTTGTGGTCAAAGAGGTTGCACCGAAGCTTATTTTAGCGCCAGCGGATTTTT
AAATCGATATAAAGAAAAGACCGGAGAAGTTTTAGATTCCGCAGAAGAATTCTTTGAAAAAACTAGAAAAGGAGATAAAA
CCGCATCGATTTTGTTAAACGAAGGTATTGACGCGCTTGCACAACTTTGTAGAAATCTAATTCATACAATCAACCCGGAG
AAAATTGTTTTTACAGGAGGACTTGTAAAGTCCTGGGATTTATTCGGTGATTCCCTACAAAATAGAATCCGGGAACTGAT
CTTTCCAATTTTCAGAACTTATACTCAAATCCTCCCCGGAGGAAACGTATCCGGCACATTAGGCGCTGCGGCGCTTTGTA
TGGAGAATTTAGAATGA

Upstream 100 bases:

>100_bases
GAGGTCTTACGATTCTATTAGTAACTCATGATATGAATTTAGCTTTTGACGCTAAAACAATTTATGAAATGAGAGAGGGA
GAATTTACCCGGGTGGTAAA

Downstream 100 bases:

>100_bases
CAGATCCAAATTGTATCTTTTGTAAAATCATCCGTAAGGAAATCCCTTCCAAAGTAGTATTTGAAAACGATGAAATATTA
GCTTTTTATGATATTTCTCC

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MKSFLGIDIGAGSIKASLIDSNGNVLKSSFRKTGAETNEKQFLDSICDIVSEMKNSSLTAVGIGSPGPIDSENGILIESA
NLPLLKNVTLVSHLKEKFSIPVYYNNDANLAALGEYHFGLGKGSPNLVILTLGTGLGGGWVYQGKLFNGYKGSGMEAGHV
TYLPNGSLCGCGQRGCTEAYFSASGFLNRYKEKTGEVLDSAEEFFEKTRKGDKTASILLNEGIDALAQLCRNLIHTINPE
KIVFTGGLVKSWDLFGDSLQNRIRELIFPIFRTYTQILPGGNVSGTLGAAALCMENLE

Sequences:

>Translated_298_residues
MKSFLGIDIGAGSIKASLIDSNGNVLKSSFRKTGAETNEKQFLDSICDIVSEMKNSSLTAVGIGSPGPIDSENGILIESA
NLPLLKNVTLVSHLKEKFSIPVYYNNDANLAALGEYHFGLGKGSPNLVILTLGTGLGGGWVYQGKLFNGYKGSGMEAGHV
TYLPNGSLCGCGQRGCTEAYFSASGFLNRYKEKTGEVLDSAEEFFEKTRKGDKTASILLNEGIDALAQLCRNLIHTINPE
KIVFTGGLVKSWDLFGDSLQNRIRELIFPIFRTYTQILPGGNVSGTLGAAALCMENLE
>Mature_298_residues
MKSFLGIDIGAGSIKASLIDSNGNVLKSSFRKTGAETNEKQFLDSICDIVSEMKNSSLTAVGIGSPGPIDSENGILIESA
NLPLLKNVTLVSHLKEKFSIPVYYNNDANLAALGEYHFGLGKGSPNLVILTLGTGLGGGWVYQGKLFNGYKGSGMEAGHV
TYLPNGSLCGCGQRGCTEAYFSASGFLNRYKEKTGEVLDSAEEFFEKTRKGDKTASILLNEGIDALAQLCRNLIHTINPE
KIVFTGGLVKSWDLFGDSLQNRIRELIFPIFRTYTQILPGGNVSGTLGAAALCMENLE

Specific function: Unknown

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=268, Percent_Identity=29.1044776119403, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI298566325, Length=268, Percent_Identity=29.1044776119403, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI4885285, Length=268, Percent_Identity=29.1044776119403, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI190014632, Length=268, Percent_Identity=29.1044776119403, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI1787363, Length=307, Percent_Identity=30.6188925081433, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787878, Length=310, Percent_Identity=23.5483870967742, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87081733, Length=300, Percent_Identity=25.6666666666667, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786891, Length=282, Percent_Identity=23.4042553191489, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87082230, Length=247, Percent_Identity=29.5546558704453, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 31922; Mature: 31922

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSFLGIDIGAGSIKASLIDSNGNVLKSSFRKTGAETNEKQFLDSICDIVSEMKNSSLTA
CCCCEEEEECCCCEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEE
VGIGSPGPIDSENGILIESANLPLLKNVTLVSHLKEKFSIPVYYNNDANLAALGEYHFGL
EECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCEEECCCCCEEEECCCCEEC
GKGSPNLVILTLGTGLGGGWVYQGKLFNGYKGSGMEAGHVTYLPNGSLCGCGQRGCTEAY
CCCCCCEEEEEECCCCCCCEEEECEEECCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHH
FSASGFLNRYKEKTGEVLDSAEEFFEKTRKGDKTASILLNEGIDALAQLCRNLIHTINPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCC
KIVFTGGLVKSWDLFGDSLQNRIRELIFPIFRTYTQILPGGNVSGTLGAAALCMENLE
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MKSFLGIDIGAGSIKASLIDSNGNVLKSSFRKTGAETNEKQFLDSICDIVSEMKNSSLTA
CCCCEEEEECCCCEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEE
VGIGSPGPIDSENGILIESANLPLLKNVTLVSHLKEKFSIPVYYNNDANLAALGEYHFGL
EECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCEEECCCCCEEEECCCCEEC
GKGSPNLVILTLGTGLGGGWVYQGKLFNGYKGSGMEAGHVTYLPNGSLCGCGQRGCTEAY
CCCCCCEEEEEECCCCCCCEEEECEEECCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHH
FSASGFLNRYKEKTGEVLDSAEEFFEKTRKGDKTASILLNEGIDALAQLCRNLIHTINPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCC
KIVFTGGLVKSWDLFGDSLQNRIRELIFPIFRTYTQILPGGNVSGTLGAAALCMENLE
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9620975 [H]