| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
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The map label for this gene is mpg1 [H]
Identifier: 45658050
GI number: 45658050
Start: 2654758
End: 2655561
Strand: Reverse
Name: mpg1 [H]
Synonym: LIC12201
Alternate gene names: 45658050
Gene position: 2655561-2654758 (Counterclockwise)
Preceding gene: 45658051
Following gene: 45658049
Centisome position: 62.09
GC content: 35.7
Gene sequence:
>804_bases TTGGCGGATCTAATTCATAAAAACGAAATTAACGTTTTAATTCTGGCGGCTGGGCTTGGAACTAGGCTAAAACCTCTTAC GGATTTTTGGCCGAAATGTTTGATGCCGATTTCCGGGAAACCTTTGCTTGAAATTTGGTTGGATCAAATTTCTCAATTAA AAGTTTCTAAAGTATTAGTAAACCTTCATTATTTGAATGAGATCGTATCTTCTTTTTTAAAAAGACCTAGATATAAAGAT TGGGTCAAATCCGTCTATGAACCAGAGTTATTAGGTACGGCAGGGACTCTTCAGAAGAACTATGATTTCTTTAAAGGGAA AACAATTCTTTTAGTTCATGGCGATAATCTTTGTTTATGCGATTTTAATTCTTTTGTTGAATTTCATTTTTTAAAAAGAC CTAAAGGTTCTCTTATAACGATGATGACGTTTCGAACTGATTCTCCCAAAAGTTGTGGGATTGTGGAGCTGGATGAAGAC GGAGTCGTTCAAAGGTTCTACGAAAAAGTGGAAAACCCTCCAGGAAATCTGGCAAATGCAGCCATCTACTTGATTGAACC AGAAGTTTTAGATTGGATTCAAGAAAGAGAATACGTAAACGATTTTAGTAATCAAGTGTTGCCAGAGTTTTTGGGAAAAA TCGCCACTTGGGAAAACAAAGATATAATGCGTGATATTGGAAATTCAGAGGCTTTGGCGAAGGCTCAAAAGGAAGTTACT TTCCCAGAAAACAATAATTTAGATGAATGGGAAACAGAATTTTTGTCGAACTCGATTCATCAGTCAATTCAGTCAATATT ATGA
Upstream 100 bases:
>100_bases GGGATTGGCGAATTATTAAAAAATATAGATTATTGGAGAGAAGCTCCAGTATGGACGCCTGATAAGATAGAAAAAGCGAC ATCCGATTGGTTTAAGTATC
Downstream 100 bases:
>100_bases TTCCCAATTCTCATAAGATCATATCTGTCGGGGATGTTTCACAACTTAGTGAAAGTCCATTAGAAGAATCTTTAGTTCTT TGTTATGGACATTTTAACGT
Product: mannose-1-phosphate guanyltransferase
Products: NA
Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]
Number of amino acids: Translated: 267; Mature: 266
Protein sequence:
>267_residues MADLIHKNEINVLILAAGLGTRLKPLTDFWPKCLMPISGKPLLEIWLDQISQLKVSKVLVNLHYLNEIVSSFLKRPRYKD WVKSVYEPELLGTAGTLQKNYDFFKGKTILLVHGDNLCLCDFNSFVEFHFLKRPKGSLITMMTFRTDSPKSCGIVELDED GVVQRFYEKVENPPGNLANAAIYLIEPEVLDWIQEREYVNDFSNQVLPEFLGKIATWENKDIMRDIGNSEALAKAQKEVT FPENNNLDEWETEFLSNSIHQSIQSIL
Sequences:
>Translated_267_residues MADLIHKNEINVLILAAGLGTRLKPLTDFWPKCLMPISGKPLLEIWLDQISQLKVSKVLVNLHYLNEIVSSFLKRPRYKD WVKSVYEPELLGTAGTLQKNYDFFKGKTILLVHGDNLCLCDFNSFVEFHFLKRPKGSLITMMTFRTDSPKSCGIVELDED GVVQRFYEKVENPPGNLANAAIYLIEPEVLDWIQEREYVNDFSNQVLPEFLGKIATWENKDIMRDIGNSEALAKAQKEVT FPENNNLDEWETEFLSNSIHQSIQSIL >Mature_266_residues ADLIHKNEINVLILAAGLGTRLKPLTDFWPKCLMPISGKPLLEIWLDQISQLKVSKVLVNLHYLNEIVSSFLKRPRYKDW VKSVYEPELLGTAGTLQKNYDFFKGKTILLVHGDNLCLCDFNSFVEFHFLKRPKGSLITMMTFRTDSPKSCGIVELDEDG VVQRFYEKVENPPGNLANAAIYLIEPEVLDWIQEREYVNDFSNQVLPEFLGKIATWENKDIMRDIGNSEALAKAQKEVTF PENNNLDEWETEFLSNSIHQSIQSIL
Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]
COG id: COG1208
COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the transferase hexapeptide repeat family [H]
Homologues:
Organism=Homo sapiens, GI11761621, Length=226, Percent_Identity=28.3185840707965, Blast_Score=85, Evalue=8e-17, Organism=Homo sapiens, GI11761619, Length=226, Percent_Identity=28.3185840707965, Blast_Score=84, Evalue=1e-16, Organism=Caenorhabditis elegans, GI133931050, Length=232, Percent_Identity=28.0172413793103, Blast_Score=83, Evalue=2e-16, Organism=Saccharomyces cerevisiae, GI6320148, Length=190, Percent_Identity=29.4736842105263, Blast_Score=87, Evalue=3e-18, Organism=Drosophila melanogaster, GI21355443, Length=207, Percent_Identity=31.4009661835749, Blast_Score=88, Evalue=5e-18, Organism=Drosophila melanogaster, GI24644084, Length=207, Percent_Identity=31.4009661835749, Blast_Score=88, Evalue=5e-18,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005835 [H]
Pfam domain/function: PF00483 NTP_transferase [H]
EC number: =2.7.7.13 [H]
Molecular weight: Translated: 30654; Mature: 30522
Theoretical pI: Translated: 4.93; Mature: 4.93
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 3.4 %Cys+Met (Translated Protein) 1.5 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MADLIHKNEINVLILAAGLGTRLKPLTDFWPKCLMPISGKPLLEIWLDQISQLKVSKVLV CCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH NLHYLNEIVSSFLKRPRYKDWVKSVYEPELLGTAGTLQKNYDFFKGKTILLVHGDNLCLC HHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHCCCHHHHHCCHHHCCCEEEEEECCCEEEE DFNSFVEFHFLKRPKGSLITMMTFRTDSPKSCGIVELDEDGVVQRFYEKVENPPGNLANA EHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCE AIYLIEPEVLDWIQEREYVNDFSNQVLPEFLGKIATWENKDIMRDIGNSEALAKAQKEVT EEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHCCC FPENNNLDEWETEFLSNSIHQSIQSIL CCCCCCCCHHHHHHHHHHHHHHHHHHC >Mature Secondary Structure ADLIHKNEINVLILAAGLGTRLKPLTDFWPKCLMPISGKPLLEIWLDQISQLKVSKVLV CCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH NLHYLNEIVSSFLKRPRYKDWVKSVYEPELLGTAGTLQKNYDFFKGKTILLVHGDNLCLC HHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHCCCHHHHHCCHHHCCCEEEEEECCCEEEE DFNSFVEFHFLKRPKGSLITMMTFRTDSPKSCGIVELDEDGVVQRFYEKVENPPGNLANA EHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCE AIYLIEPEVLDWIQEREYVNDFSNQVLPEFLGKIATWENKDIMRDIGNSEALAKAQKEVT EEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHCCC FPENNNLDEWETEFLSNSIHQSIQSIL CCCCCCCCHHHHHHHHHHHHHHHHHHC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8334170 [H]