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The map label for this gene is degT [H]

Identifier: 45658046

GI number: 45658046

Start: 2650019

End: 2651122

Strand: Reverse

Name: degT [H]

Synonym: LIC12197

Alternate gene names: 45658046

Gene position: 2651122-2650019 (Counterclockwise)

Preceding gene: 45658047

Following gene: 45658045

Centisome position: 61.98

GC content: 37.41

Gene sequence:

>1104_bases
ATGATAAATATTCCTTATATAAATTTAGTTGAGCAGTGGAAAAACGAACGGGAAGAATTACTTCCGGTTCTTGATTCCGT
TTTAGGTTCCGGTCAGTACATTGGTGGACAAGAAGTCGCAAAGTTTGAAGAGGATGTCGCAAAGTTCTGCGGAGTGAAAT
ACGCGGTTGCTTTAAATAGTGGAACCGATGCGCTCGTATGTGGACTTTTAGAACTTGGTATTCAACCGGGCGATGAAGTG
ATTACTCCTCCAAACTCTTTTATTGCTTCTACGGCTTCGATTGTTCATATAAAAGCGAAACCAGTATTTGTCGATGTAGG
AGAGGACCAGAATCTAGATCCGGAAAAATTGGAAAAGGCTATCACGTCTAAAACAAAAGCGATTATGCCTGTTCATCTAA
CTGGCCGGGTTGCCGCGATGAATGAAATTATGAGGATTGCAGACAAATATTCTATACCCGTAATTGAAGATGCAGCACAA
TCTATTGGTTCTAAATATGATGGTAAGTTTAGTGGTTCTATTGGTAAAATTGGATGTTTCTCTACCCATCCATTAAAGAA
TTTAAATGCTTGCGGTGATGGTGGATTTTTGACAACAAATGATGAGAAGATTTATAACTCTGTAAGTAGGGTTAGAAATC
ATGGTCTAATTGATAGGAATACTGTCGGTGAATTTGGTTTTGTAACGAGAATGGATGCAATTCAGGCGGCGATTTTAAAT
TTCCGTTTAACGCGTTTGCCGCAAGTTATTGAAAAAAGACGTCAGAATGCACAACTTTATAAAACCTTATTAGATAAAAG
GAATGTTTTTATCCCGGAAGATAAACCTTTAGAATTTAATACTTATCATACTTTCGTAATACAAGTCGAAAGAAGAGATG
AATTAAAAGATTATTTATTTTCACAGGGGATTGAGACATCCATTCATTATCCGATTCCCATCCATCTTCAACCCGCTAGT
AGGAATCTTGGATATAAACAGGGAGACTTCCCTATTACGGAAAAACAAGCGGGCCGAATTTTAACTTTGCCCATTCATCA
ATATTTGAAAGATGTTGACTTACATAAAATTGCCCAAGCGGTTAATCGTTTCTACGAATCGTAA

Upstream 100 bases:

>100_bases
AAAAGATTATTACATTCCCTTGTGATCAACATCTTTCAAAGGAAGAAATGGATTATGTTGTTTCTATTATAAAAGAATTC
TATTCTAAGTAAATGATCCG

Downstream 100 bases:

>100_bases
ATGAAGATAGGAATTGATTTAGATAACACGATTATATCATACGATAAATCATTTGCTTTTGTGGGTAAAAAGATAGGTTT
AATTCCGGAAAATTGGTTTG

Product: aminotransferase

Products: TDP-D-fucosamine; 2-oxoglutarate [C]

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MINIPYINLVEQWKNEREELLPVLDSVLGSGQYIGGQEVAKFEEDVAKFCGVKYAVALNSGTDALVCGLLELGIQPGDEV
ITPPNSFIASTASIVHIKAKPVFVDVGEDQNLDPEKLEKAITSKTKAIMPVHLTGRVAAMNEIMRIADKYSIPVIEDAAQ
SIGSKYDGKFSGSIGKIGCFSTHPLKNLNACGDGGFLTTNDEKIYNSVSRVRNHGLIDRNTVGEFGFVTRMDAIQAAILN
FRLTRLPQVIEKRRQNAQLYKTLLDKRNVFIPEDKPLEFNTYHTFVIQVERRDELKDYLFSQGIETSIHYPIPIHLQPAS
RNLGYKQGDFPITEKQAGRILTLPIHQYLKDVDLHKIAQAVNRFYES

Sequences:

>Translated_367_residues
MINIPYINLVEQWKNEREELLPVLDSVLGSGQYIGGQEVAKFEEDVAKFCGVKYAVALNSGTDALVCGLLELGIQPGDEV
ITPPNSFIASTASIVHIKAKPVFVDVGEDQNLDPEKLEKAITSKTKAIMPVHLTGRVAAMNEIMRIADKYSIPVIEDAAQ
SIGSKYDGKFSGSIGKIGCFSTHPLKNLNACGDGGFLTTNDEKIYNSVSRVRNHGLIDRNTVGEFGFVTRMDAIQAAILN
FRLTRLPQVIEKRRQNAQLYKTLLDKRNVFIPEDKPLEFNTYHTFVIQVERRDELKDYLFSQGIETSIHYPIPIHLQPAS
RNLGYKQGDFPITEKQAGRILTLPIHQYLKDVDLHKIAQAVNRFYES
>Mature_367_residues
MINIPYINLVEQWKNEREELLPVLDSVLGSGQYIGGQEVAKFEEDVAKFCGVKYAVALNSGTDALVCGLLELGIQPGDEV
ITPPNSFIASTASIVHIKAKPVFVDVGEDQNLDPEKLEKAITSKTKAIMPVHLTGRVAAMNEIMRIADKYSIPVIEDAAQ
SIGSKYDGKFSGSIGKIGCFSTHPLKNLNACGDGGFLTTNDEKIYNSVSRVRNHGLIDRNTVGEFGFVTRMDAIQAAILN
FRLTRLPQVIEKRRQNAQLYKTLLDKRNVFIPEDKPLEFNTYHTFVIQVERRDELKDYLFSQGIETSIHYPIPIHLQPAS
RNLGYKQGDFPITEKQAGRILTLPIHQYLKDVDLHKIAQAVNRFYES

Specific function: This membrane protein may function as a sensor protein and may transfer the signal of environmental stimuli to the regulatory region of target genes to activate or repress transcription of the genes [H]

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family [H]

Homologues:

Organism=Escherichia coli, GI2367285, Length=363, Percent_Identity=33.0578512396694, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI145693159, Length=367, Percent_Identity=31.0626702997275, Blast_Score=157, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01041 DegT_DnrJ_EryC1 [H]

EC number: NA

Molecular weight: Translated: 41050; Mature: 41050

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINIPYINLVEQWKNEREELLPVLDSVLGSGQYIGGQEVAKFEEDVAKFCGVKYAVALNS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECC
GTDALVCGLLELGIQPGDEVITPPNSFIASTASIVHIKAKPVFVDVGEDQNLDPEKLEKA
CCHHHHHHHHHHCCCCCCCEECCCCHHHHCCEEEEEEEECEEEEECCCCCCCCHHHHHHH
ITSKTKAIMPVHLTGRVAAMNEIMRIADKYSIPVIEDAAQSIGSKYDGKFSGSIGKIGCF
HHHHHHEEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCEECC
STHPLKNLNACGDGGFLTTNDEKIYNSVSRVRNHGLIDRNTVGEFGFVTRMDAIQAAILN
CCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
FRLTRLPQVIEKRRQNAQLYKTLLDKRNVFIPEDKPLEFNTYHTFVIQVERRDELKDYLF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCEEECEEEEEEEECCHHHHHHHHH
SQGIETSIHYPIPIHLQPASRNLGYKQGDFPITEKQAGRILTLPIHQYLKDVDLHKIAQA
HCCCCCCEECCEEEEEECCCCCCCCCCCCCCCCHHHCCCEEEEEHHHHHHHCCHHHHHHH
VNRFYES
HHHHHCC
>Mature Secondary Structure
MINIPYINLVEQWKNEREELLPVLDSVLGSGQYIGGQEVAKFEEDVAKFCGVKYAVALNS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECC
GTDALVCGLLELGIQPGDEVITPPNSFIASTASIVHIKAKPVFVDVGEDQNLDPEKLEKA
CCHHHHHHHHHHCCCCCCCEECCCCHHHHCCEEEEEEEECEEEEECCCCCCCCHHHHHHH
ITSKTKAIMPVHLTGRVAAMNEIMRIADKYSIPVIEDAAQSIGSKYDGKFSGSIGKIGCF
HHHHHHEEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCEECC
STHPLKNLNACGDGGFLTTNDEKIYNSVSRVRNHGLIDRNTVGEFGFVTRMDAIQAAILN
CCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
FRLTRLPQVIEKRRQNAQLYKTLLDKRNVFIPEDKPLEFNTYHTFVIQVERRDELKDYLF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCEEECEEEEEEEECCHHHHHHHHH
SQGIETSIHYPIPIHLQPASRNLGYKQGDFPITEKQAGRILTLPIHQYLKDVDLHKIAQA
HCCCCCCEECCEEEEEECCCCCCCCCCCCCCCCHHHCCCEEEEEHHHHHHHCCHHHHHHH
VNRFYES
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dTDP-4-dehydro-6-deoxy-D-glucose; L-glutamate [C]

Specific reaction: dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate = TDP-D-fucosamine + 2-oxoglutarate [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2104607 [H]