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The map label for this gene is fmt [H]

Identifier: 45658035

GI number: 45658035

Start: 2639681

End: 2640607

Strand: Reverse

Name: fmt [H]

Synonym: LIC12186

Alternate gene names: 45658035

Gene position: 2640607-2639681 (Counterclockwise)

Preceding gene: 45658036

Following gene: 45658034

Centisome position: 61.74

GC content: 31.61

Gene sequence:

>927_bases
ATGGATGAAAGATATATTGTTATCGGAACTTCACAAGCTACTCTTGAATGTATCAAGGCGCTTTTGGATTCTAAAAAAAG
TATAGTAGGAGTATTTTCACTTCCTAAGGGAAAATTACCTGACAACTCTATAGGCTTAAGCTATTGTCAAAAAGAATATG
GTATTCCCTATTTTGAAGTTGAAGACTTAAACTCTGCCTCATCGGAAGAAACTATTGCTAAATTAAATCCAGATTATATA
ATTTCTACCTGGCCGAAAATTATTTCTAAAAAAATTATTTCAATTCCAAAAAAATTGATTGGGACACATCCTACTCCTTT
ACCTTTCAATAAAGGACGTCATCCTTTGCACTGGATGATTGTTTTAGGTATTCCTAATTCGGTTGTTACTTTTTTTGAAA
TGGATGAAGGGGTTGATTCTGGAAAAGTTTTACTGCAGATTCCATTTCAAATTGGATTAAAGCAGATTCATGATCTTGTA
ATTAGAATGAATAAAGCTATTTATGATGGTGTAGTAAAATTAGTCAGAATATTAGAAACAAATCCTGACTTTCCTGGCTC
TTTACAAAATCATAATGAAGGGAATTACTGGAGGACAAGGACGGAAGACGATGTTACCTTAGATCCAAGAATGACTGCTT
CTATGATAAAAAGAATTGTTCGTTCATTTTCTTCGCCATACCCTAATGCAAATTTATACTATAAACAAAATCTATATATA
AAAATTGAACACGCAGAAGAGATCGATGAGACCGAACTTCCTCCAAATTGGCAAAGTTTAGAACATGGGCAAGTTCTTTG
TGTAACCAATACTTTTTTAGATTTAAAAGTAGATGGTTCTGTAGTTCGATTATTTTATATAAATCAAATTGAAGAAATAT
TAAAAGATGTTAAAAGAATACATCCTCCGACTTATTATTTACGTTAA

Upstream 100 bases:

>100_bases
AATTCTAGAAAATACGGTCTTAAGGGAATTTACTTACCTAGTGGCCCATCCCAAAAAATTGATAGTATAAAATTTGTTAT
TGAACAAATTAAAAATATTT

Downstream 100 bases:

>100_bases
ATGCTTCTATGTTTTAGTATAATTATTCACCAAAGGTGATATATTTGCTTGTTGGACTTCCTATGGAATAGGAGTTAGCA
ATGGAATAGATGTTGTTCAT

Product: methionyl-tRNA(fmet) n-formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MDERYIVIGTSQATLECIKALLDSKKSIVGVFSLPKGKLPDNSIGLSYCQKEYGIPYFEVEDLNSASSEETIAKLNPDYI
ISTWPKIISKKIISIPKKLIGTHPTPLPFNKGRHPLHWMIVLGIPNSVVTFFEMDEGVDSGKVLLQIPFQIGLKQIHDLV
IRMNKAIYDGVVKLVRILETNPDFPGSLQNHNEGNYWRTRTEDDVTLDPRMTASMIKRIVRSFSSPYPNANLYYKQNLYI
KIEHAEEIDETELPPNWQSLEHGQVLCVTNTFLDLKVDGSVVRLFYINQIEEILKDVKRIHPPTYYLR

Sequences:

>Translated_308_residues
MDERYIVIGTSQATLECIKALLDSKKSIVGVFSLPKGKLPDNSIGLSYCQKEYGIPYFEVEDLNSASSEETIAKLNPDYI
ISTWPKIISKKIISIPKKLIGTHPTPLPFNKGRHPLHWMIVLGIPNSVVTFFEMDEGVDSGKVLLQIPFQIGLKQIHDLV
IRMNKAIYDGVVKLVRILETNPDFPGSLQNHNEGNYWRTRTEDDVTLDPRMTASMIKRIVRSFSSPYPNANLYYKQNLYI
KIEHAEEIDETELPPNWQSLEHGQVLCVTNTFLDLKVDGSVVRLFYINQIEEILKDVKRIHPPTYYLR
>Mature_308_residues
MDERYIVIGTSQATLECIKALLDSKKSIVGVFSLPKGKLPDNSIGLSYCQKEYGIPYFEVEDLNSASSEETIAKLNPDYI
ISTWPKIISKKIISIPKKLIGTHPTPLPFNKGRHPLHWMIVLGIPNSVVTFFEMDEGVDSGKVLLQIPFQIGLKQIHDLV
IRMNKAIYDGVVKLVRILETNPDFPGSLQNHNEGNYWRTRTEDDVTLDPRMTASMIKRIVRSFSSPYPNANLYYKQNLYI
KIEHAEEIDETELPPNWQSLEHGQVLCVTNTFLDLKVDGSVVRLFYINQIEEILKDVKRIHPPTYYLR

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Escherichia coli, GI1788589, Length=224, Percent_Identity=27.2321428571429, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1789683, Length=256, Percent_Identity=23.828125, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR001555
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 35246; Mature: 35246

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDERYIVIGTSQATLECIKALLDSKKSIVGVFSLPKGKLPDNSIGLSYCQKEYGIPYFEV
CCCCEEEEECCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCEEEE
EDLNSASSEETIAKLNPDYIISTWPKIISKKIISIPKKLIGTHPTPLPFNKGRHPLHWMI
CCCCCCCCCHHHHHCCCCEEEHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCEEEEE
VLGIPNSVVTFFEMDEGVDSGKVLLQIPFQIGLKQIHDLVIRMNKAIYDGVVKLVRILET
EEECCCCEEEEEEECCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NPDFPGSLQNHNEGNYWRTRTEDDVTLDPRMTASMIKRIVRSFSSPYPNANLYYKQNLYI
CCCCCCCCCCCCCCCCEECCCCCCCEECCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEE
KIEHAEEIDETELPPNWQSLEHGQVLCVTNTFLDLKVDGSVVRLFYINQIEEILKDVKRI
EEECCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEEEECCCEEEEEEHHHHHHHHHHHHHH
HPPTYYLR
CCCCCCCC
>Mature Secondary Structure
MDERYIVIGTSQATLECIKALLDSKKSIVGVFSLPKGKLPDNSIGLSYCQKEYGIPYFEV
CCCCEEEEECCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCEEEE
EDLNSASSEETIAKLNPDYIISTWPKIISKKIISIPKKLIGTHPTPLPFNKGRHPLHWMI
CCCCCCCCCHHHHHCCCCEEEHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCEEEEE
VLGIPNSVVTFFEMDEGVDSGKVLLQIPFQIGLKQIHDLVIRMNKAIYDGVVKLVRILET
EEECCCCEEEEEEECCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NPDFPGSLQNHNEGNYWRTRTEDDVTLDPRMTASMIKRIVRSFSSPYPNANLYYKQNLYI
CCCCCCCCCCCCCCCCEECCCCCCCEECCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEE
KIEHAEEIDETELPPNWQSLEHGQVLCVTNTFLDLKVDGSVVRLFYINQIEEILKDVKRI
EEECCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEEEECCCEEEEEEHHHHHHHHHHHHHH
HPPTYYLR
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA