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The map label for this gene is fcI

Identifier: 45658034

GI number: 45658034

Start: 2639111

End: 2639410

Strand: Reverse

Name: fcI

Synonym: LIC12185

Alternate gene names: 45658034

Gene position: 2639410-2639111 (Counterclockwise)

Preceding gene: 45658035

Following gene: 45658033

Centisome position: 61.71

GC content: 40.67

Gene sequence:

>300_bases
TTGTCAAGTTGTGAATTTGGAGATGTCTGGCTTCATAAAATATTTTATAAATTTCTTGAAAACTCGGTTGAAAATATCGG
CGGCGGTATCTCGTTTACAAGTCAAGATTGGTCGAGCACCAAGGCGAGGGAACACGTCAAAATAGGAAGCAGAATCGAAA
CGGGCATCTGTGAACTCGCCGAAACCGTTAAGGAAGTAGAGGGTTTTAGGTATTTTGACTTTCGATCTGACGAAATTCCT
TGTAAACTTTTGGACGTTTCTAAACTTCATAGGATGAGCTGGAAGTACCAAGTGAAGTGA

Upstream 100 bases:

>100_bases
ATTTCTTCTACCGATAAAAGATTGAATTGAAATGTCCTTCGATCAAACGAAGAAGTTTAGGATGAAAAAGAAAGAAAAAG
CGTCTTGAATAGAAGAAGAA

Downstream 100 bases:

>100_bases
AATGAAGGGTCTGCTGGGCAAATTCATTCTTGGTTTGAAGAGGCTGGTTTAGGTAAAGTTGTTTATTTTATTCATCCGGG
AGAGACTCTTCCTGAAATTA

Product: fucose synthetase

Products: GDP-4-dehydro-6-L-deoxygalactose; guanosine diphosphate fucose; NADP [C]

Alternate protein names: NA

Number of amino acids: Translated: 99; Mature: 98

Protein sequence:

>99_residues
MSSCEFGDVWLHKIFYKFLENSVENIGGGISFTSQDWSSTKAREHVKIGSRIETGICELAETVKEVEGFRYFDFRSDEIP
CKLLDVSKLHRMSWKYQVK

Sequences:

>Translated_99_residues
MSSCEFGDVWLHKIFYKFLENSVENIGGGISFTSQDWSSTKAREHVKIGSRIETGICELAETVKEVEGFRYFDFRSDEIP
CKLLDVSKLHRMSWKYQVK
>Mature_98_residues
SSCEFGDVWLHKIFYKFLENSVENIGGGISFTSQDWSSTKAREHVKIGSRIETGICELAETVKEVEGFRYFDFRSDEIPC
KLLDVSKLHRMSWKYQVK

Specific function: Two Step Nadp-Dependent Conversion Of Gdp-4-Dehydro-6- Deoxy-D-Mannose To Gdp-Fucose, Involving An Epimerase And A Reductase Reaction. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.1.1.271 [C]

Molecular weight: Translated: 11531; Mature: 11400

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSCEFGDVWLHKIFYKFLENSVENIGGGISFTSQDWSSTKAREHVKIGSRIETGICELA
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHH
ETVKEVEGFRYFDFRSDEIPCKLLDVSKLHRMSWKYQVK
HHHHHHCCCEEECCCCCCCCEEHCCHHHHHHCCCEEECC
>Mature Secondary Structure 
SSCEFGDVWLHKIFYKFLENSVENIGGGISFTSQDWSSTKAREHVKIGSRIETGICELA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHH
ETVKEVEGFRYFDFRSDEIPCKLLDVSKLHRMSWKYQVK
HHHHHHCCCEEECCCCCCCCEEHCCHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GDP-4-dehydro-6-deoxy-D-mannose; GDP-4-dehydro-6-L-deoxygalactose; NADPH; Proton [C]

Specific reaction: GDP-4-dehydro-6-deoxy-D-mannose = GDP-4-dehydro-6-L-deoxygalactose GDP-4-dehydro-6-L-deoxygalactose + NADPH + Proton = guanosine diphosphate fucose + NADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA