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The map label for this gene is barA [C]

Identifier: 45657907

GI number: 45657907

Start: 2492609

End: 2493214

Strand: Reverse

Name: barA [C]

Synonym: LIC12059

Alternate gene names: 45657907

Gene position: 2493214-2492609 (Counterclockwise)

Preceding gene: 45657908

Following gene: 45657906

Centisome position: 58.29

GC content: 35.64

Gene sequence:

>606_bases
ATGGAAAAGATCAAGAATGGACGGATTCCTCCTATAGTCATTTATACGGGTAGAGGACTTACAAAAGAAGAGATAAAGAC
TTCAGAAATTTCTGAAAGTATCATTATTAAAGGTATTAAGTCCGAAGAAAGGTTGTTGGACGAGACCGCGTTATTCCTTC
ATAGGATGATTAATGATCTTCCAGAAGCAAAACAGAATATTATAAATAATTTATACGATAAAGACTCGGTTTTATTTCAA
AAGAAAATACTTTTGGTTGATGACGACATGAGAAACGTTTTTGCGTTATCTAAAATACTTAGTGAAAAAGGAATGAACGT
TTTAAAGGCGGAGGATGGAAACAGCGCTTTGGAATTACTTTCTAAAAACGAGGACGTAGACTTGGTTCTTATGGATATAA
TGATGCCAGAGATGGACGGTTACGAAACAATGAAAAAGATCCGGGAAATTTCGAAGTATAAAAATCTCACTATTATCGCT
TTGACCGCAAAAGCGATGCAAAACGATCGACAGAAATGTATAGAGGCCGGTGCAAATGATTATATACCCAAGCCGGTTGA
TGTAGAACGTTTGTTTTCTTTGATGAGGGTTTGGTTAAGTAAATAG

Upstream 100 bases:

>100_bases
TCTGGTAAGGAAGTCTTAGAGTCTACGCCGAAAATCATTTTGATTGTATTGTTTTAGATAAAGGACTTCCCGCAATGAGT
GTTTTGAGCTGATTCAAGAA

Downstream 100 bases:

>100_bases
AAGGTTAAAGATCATGAAATCAAAACCGAAAATACTAATCGTAGACGATAAGCCTGAAAACCTGATCGCCCTAGAAGTTG
TGTTAAAGGATTTGGACGTA

Product: response regulator

Products: NA

Alternate protein names: ORF131 [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MEKIKNGRIPPIVIYTGRGLTKEEIKTSEISESIIIKGIKSEERLLDETALFLHRMINDLPEAKQNIINNLYDKDSVLFQ
KKILLVDDDMRNVFALSKILSEKGMNVLKAEDGNSALELLSKNEDVDLVLMDIMMPEMDGYETMKKIREISKYKNLTIIA
LTAKAMQNDRQKCIEAGANDYIPKPVDVERLFSLMRVWLSK

Sequences:

>Translated_201_residues
MEKIKNGRIPPIVIYTGRGLTKEEIKTSEISESIIIKGIKSEERLLDETALFLHRMINDLPEAKQNIINNLYDKDSVLFQ
KKILLVDDDMRNVFALSKILSEKGMNVLKAEDGNSALELLSKNEDVDLVLMDIMMPEMDGYETMKKIREISKYKNLTIIA
LTAKAMQNDRQKCIEAGANDYIPKPVDVERLFSLMRVWLSK
>Mature_201_residues
MEKIKNGRIPPIVIYTGRGLTKEEIKTSEISESIIIKGIKSEERLLDETALFLHRMINDLPEAKQNIINNLYDKDSVLFQ
KKILLVDDDMRNVFALSKILSEKGMNVLKAEDGNSALELLSKNEDVDLVLMDIMMPEMDGYETMKKIREISKYKNLTIIA
LTAKAMQNDRQKCIEAGANDYIPKPVDVERLFSLMRVWLSK

Specific function: Member Of The Two-Component Regulatory System Uvry/Bara Involved In The Regulation Of Carbon Metabolism Via The Csra/Csrb Regulatory System. Phosphorylates Uvry, Probably Via A Four-Step Phosphorelay. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=152, Percent_Identity=31.5789473684211, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI145693157, Length=132, Percent_Identity=35.6060606060606, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87082012, Length=120, Percent_Identity=35, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1789809, Length=120, Percent_Identity=36.6666666666667, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786599, Length=120, Percent_Identity=31.6666666666667, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1786784, Length=120, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI2367329, Length=120, Percent_Identity=39.1666666666667, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790299, Length=113, Percent_Identity=31.858407079646, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790437, Length=109, Percent_Identity=35.7798165137615, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1788550, Length=110, Percent_Identity=36.3636363636364, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1786911, Length=119, Percent_Identity=30.2521008403361, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788713, Length=109, Percent_Identity=37.6146788990826, Blast_Score=61, Evalue=6e-11,
Organism=Escherichia coli, GI1790863, Length=120, Percent_Identity=32.5, Blast_Score=60, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=119, Percent_Identity=34.453781512605, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322000, Length=144, Percent_Identity=34.7222222222222, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 23036; Mature: 23036

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKIKNGRIPPIVIYTGRGLTKEEIKTSEISESIIIKGIKSEERLLDETALFLHRMINDL
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
PEAKQNIINNLYDKDSVLFQKKILLVDDDMRNVFALSKILSEKGMNVLKAEDGNSALELL
HHHHHHHHHHHHCCHHHHHHHHEEEEECHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHH
SKNEDVDLVLMDIMMPEMDGYETMKKIREISKYKNLTIIALTAKAMQNDRQKCIEAGAND
HCCCCCCEEHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCC
YIPKPVDVERLFSLMRVWLSK
CCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MEKIKNGRIPPIVIYTGRGLTKEEIKTSEISESIIIKGIKSEERLLDETALFLHRMINDL
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
PEAKQNIINNLYDKDSVLFQKKILLVDDDMRNVFALSKILSEKGMNVLKAEDGNSALELL
HHHHHHHHHHHHCCHHHHHHHHEEEEECHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHH
SKNEDVDLVLMDIMMPEMDGYETMKKIREISKYKNLTIIALTAKAMQNDRQKCIEAGAND
HCCCCCCEEHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCC
YIPKPVDVERLFSLMRVWLSK
CCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7860607 [H]