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The map label for this gene is nhaA2 [H]

Identifier: 45657648

GI number: 45657648

Start: 2174079

End: 2175125

Strand: Reverse

Name: nhaA2 [H]

Synonym: LIC11782

Alternate gene names: 45657648

Gene position: 2175125-2174079 (Counterclockwise)

Preceding gene: 45657651

Following gene: 161621774

Centisome position: 50.85

GC content: 36.1

Gene sequence:

>1047_bases
ATGAAAGACATAATCGAAAAACTGAAAACTAAGGAATTCAGACCCCTGCTGATACTTTCAGCCATTTTTTTGATTTATAT
CGCGTTTACCATTTTTCCGCTAATTTCGTATTTTTCTCCTGACGGAGTCGTTGAAATTAACGGCAAAAATTATACGATCA
AAGACGTTGAAAAGGAAAATCCTAGAATTGCTCGTAAGTTCTATTCGGAAACAAATGATCGTCTTTATCGTGTTCTTTCC
GAATTTGCTAGTAAAAAAGTAGTATCTCTCGCGGCAAAAGAGCGTAATGTTTCTGAAAAAGAACTTTTGGAACCTTCGGT
CTCGGCTCCTAGTATCGAAGAAATGAGAGCCGTCTATGAACAATATAAGAATTCTCCAGCATTAAAAGGAAAGTCTTTTG
ATCAGGTGAAAGCCGAAATCGAAAATCATCTCATTTCGCAAAAGAAAGAAGAAGCAAGAAATAATTTCTTTGGACAACTT
CGAAATCAATATAATATTTCCGTAAAGGTCAAAGAACTTCCCCCTCTTAGAGATAATACAATTCTGGCTGGAAATAATCC
TTCTATCGGACCAGAAAACGCAAAAGTCACCGTGATAGAGTTTTCTGATTTTGAATGTCCATTCTGTAAAAGAAGTCAGT
CAGTAAATTCTCAGTTAAGAGAAAAATACAAAGATCAAATCCGTTGGGTTTTTAGGGATTATCCTCTTTCTTTTCATCCA
AACGCAATGTTTGCGCATATTGCGGCTAATTGTTCTGCTTCTCAGGGAAAGTATTGGGAATTTTTTAAAGTTCTTTTTGA
CAATTCCGGAAATCTTCCTAAAGACAGAGTTTTGGATTTAGCAAGAGGGCTAGGGTTGGATATGAAAGTTTTTAGTCAAT
GTGTGAATGATTCTGAAGTGCGTAAGGAAGTAGAAGCAGATATGGCGGAAGGTGAAAAATACGGAGTCAGTGGAACACCT
GCGTTTTTTATCAACGGAGTTATGATAGAAGGTGCTCAACCGATAGAAGCTTTTATTAAGGTAATTGATCAAGAACTTAA
AAATTAA

Upstream 100 bases:

>100_bases
AAATCCGAATTTATAGTTTGCCACCCTGTCTCAGATTTCTAAGTTGGCAAGTAGGGGAAACTAAGTCGTCGTTTTTCCGA
CCATTGGAGGGAATATTTCC

Downstream 100 bases:

>100_bases
AATTAGAAATTAGGAGTCACCCAAATATGAGTAAGACTGTAAAAGTCGCTGTTACAGGCGCTGCGGGACAAATCGGATAT
TCTTTACTTTTTAGAATTGC

Product: hypothetical protein

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA 2 [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MKDIIEKLKTKEFRPLLILSAIFLIYIAFTIFPLISYFSPDGVVEINGKNYTIKDVEKENPRIARKFYSETNDRLYRVLS
EFASKKVVSLAAKERNVSEKELLEPSVSAPSIEEMRAVYEQYKNSPALKGKSFDQVKAEIENHLISQKKEEARNNFFGQL
RNQYNISVKVKELPPLRDNTILAGNNPSIGPENAKVTVIEFSDFECPFCKRSQSVNSQLREKYKDQIRWVFRDYPLSFHP
NAMFAHIAANCSASQGKYWEFFKVLFDNSGNLPKDRVLDLARGLGLDMKVFSQCVNDSEVRKEVEADMAEGEKYGVSGTP
AFFINGVMIEGAQPIEAFIKVIDQELKN

Sequences:

>Translated_348_residues
MKDIIEKLKTKEFRPLLILSAIFLIYIAFTIFPLISYFSPDGVVEINGKNYTIKDVEKENPRIARKFYSETNDRLYRVLS
EFASKKVVSLAAKERNVSEKELLEPSVSAPSIEEMRAVYEQYKNSPALKGKSFDQVKAEIENHLISQKKEEARNNFFGQL
RNQYNISVKVKELPPLRDNTILAGNNPSIGPENAKVTVIEFSDFECPFCKRSQSVNSQLREKYKDQIRWVFRDYPLSFHP
NAMFAHIAANCSASQGKYWEFFKVLFDNSGNLPKDRVLDLARGLGLDMKVFSQCVNDSEVRKEVEADMAEGEKYGVSGTP
AFFINGVMIEGAQPIEAFIKVIDQELKN
>Mature_348_residues
MKDIIEKLKTKEFRPLLILSAIFLIYIAFTIFPLISYFSPDGVVEINGKNYTIKDVEKENPRIARKFYSETNDRLYRVLS
EFASKKVVSLAAKERNVSEKELLEPSVSAPSIEEMRAVYEQYKNSPALKGKSFDQVKAEIENHLISQKKEEARNNFFGQL
RNQYNISVKVKELPPLRDNTILAGNNPSIGPENAKVTVIEFSDFECPFCKRSQSVNSQLREKYKDQIRWVFRDYPLSFHP
NAMFAHIAANCSASQGKYWEFFKVLFDNSGNLPKDRVLDLARGLGLDMKVFSQCVNDSEVRKEVEADMAEGEKYGVSGTP
AFFINGVMIEGAQPIEAFIKVIDQELKN

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 39758; Mature: 39758

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDIIEKLKTKEFRPLLILSAIFLIYIAFTIFPLISYFSPDGVVEINGKNYTIKDVEKEN
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCC
PRIARKFYSETNDRLYRVLSEFASKKVVSLAAKERNVSEKELLEPSVSAPSIEEMRAVYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHH
QYKNSPALKGKSFDQVKAEIENHLISQKKEEARNNFFGQLRNQYNISVKVKELPPLRDNT
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCE
ILAGNNPSIGPENAKVTVIEFSDFECPFCKRSQSVNSQLREKYKDQIRWVFRDYPLSFHP
EEECCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
NAMFAHIAANCSASQGKYWEFFKVLFDNSGNLPKDRVLDLARGLGLDMKVFSQCVNDSEV
CHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHCCHHHH
RKEVEADMAEGEKYGVSGTPAFFINGVMIEGAQPIEAFIKVIDQELKN
HHHHHHHHHCCCCCCCCCCCHHEEECEEECCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKDIIEKLKTKEFRPLLILSAIFLIYIAFTIFPLISYFSPDGVVEINGKNYTIKDVEKEN
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCC
PRIARKFYSETNDRLYRVLSEFASKKVVSLAAKERNVSEKELLEPSVSAPSIEEMRAVYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHH
QYKNSPALKGKSFDQVKAEIENHLISQKKEEARNNFFGQLRNQYNISVKVKELPPLRDNT
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCE
ILAGNNPSIGPENAKVTVIEFSDFECPFCKRSQSVNSQLREKYKDQIRWVFRDYPLSFHP
EEECCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
NAMFAHIAANCSASQGKYWEFFKVLFDNSGNLPKDRVLDLARGLGLDMKVFSQCVNDSEV
CHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHCCHHHH
RKEVEADMAEGEKYGVSGTPAFFINGVMIEGAQPIEAFIKVIDQELKN
HHHHHHHHHCCCCCCCCCCCHHEEECEEECCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA