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The map label for this gene is ywlC [H]

Identifier: 45657585

GI number: 45657585

Start: 2094502

End: 2095449

Strand: Reverse

Name: ywlC [H]

Synonym: LIC11719

Alternate gene names: 45657585

Gene position: 2095449-2094502 (Counterclockwise)

Preceding gene: 45657586

Following gene: 45657583

Centisome position: 48.99

GC content: 34.49

Gene sequence:

>948_bases
TTGTCGGAAAACAAGGTTAACACTTTAATCACAGATTCAACTTCGGAGGCGGCAAAAATTTTGCTGAAAGGAGGGCTTGT
CGTTTTTCCTACGGAAACGGTCTATGGCATCGGAGCTTCCGCTTTTGACATAGACGCTTGTAAACGAATCTATAAAGTAA
AGAACAGACCTTCCGACAATCCTCTTATACTTCACGTGGCAAATTTTTCTTCTCTTAAAGATTGTGGGGAAATTGACGAT
AGGGCCAATCTGGTTTTCCAAAAACTTTCTCCTGGCCCGATTACAGGAATTTTCAAAAAGAAAAATCAAAATCTTTTTAC
AGCTGGATTAGATTCGGTTGCCATTCGAATTCCTTCCAATCCTACAGCTTTAGGTTTTTTAAAATTCTGTAAAATTCCGG
TTGCAGCTCCTTCTGCTAATTTTTCGGGAAAACCATCCTTAACAAAAATAGAATATATTTTGGAAGAATTTATTGGAAAA
GTGGACTGTATTCTAAAAGGTGAAGAACCTCAAATAGGAATTGAATCCACGGTGGTTGATTTTATTTCTAAACCTCCAAT
TTTACTTCGCCCTGGTTTTATAGATAAAAATGACCTTTCAGAAATTTTACCAGACCTTCAAGAAATGAAATCATTAGACA
AAAATTCCTATACGACGCCTATAAGTCCTGGTCTTAAATACAAACATTATTCTCCCAATTGCAAAGTTATATTCAAAAAT
TCTTTAAAAGGAATTCCTAAAGAATTTGCTCAAATTGGTTTTCATTTTGAATCCAATTCGGTTTATCAAGTTTTAGTTTC
ATCTAACAAAGAATATATGAAGGAAATCTATTCTTTTTTTGTGGAATGCGATCGTAGAGGAATTACAGAAGCATGGTGTG
AAATTCCAAAAGAAGAGAAATGGAAAGAAGTGCTGATTAATCGAATTTCAAAAGCTGCTTCAAAATAA

Upstream 100 bases:

>100_bases
GAAAAAATAAAAGAACCGGTTCAAGATCCAAATAAATCTAAAGTAGAGCCTACCAATCCAGAAGAAGCAAAGATAGATTC
TCAAGATCATTCTGAAAAGT

Downstream 100 bases:

>100_bases
AAGAATTTTACACTTCAACCATAGAGTTGTTAAAAAATAAATTCTCCTTCTGTTTTATGGGAACGGGTCGATGGAAGCAG
TTAATATCCACTTTCAACAA

Product: hypothetical protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MSENKVNTLITDSTSEAAKILLKGGLVVFPTETVYGIGASAFDIDACKRIYKVKNRPSDNPLILHVANFSSLKDCGEIDD
RANLVFQKLSPGPITGIFKKKNQNLFTAGLDSVAIRIPSNPTALGFLKFCKIPVAAPSANFSGKPSLTKIEYILEEFIGK
VDCILKGEEPQIGIESTVVDFISKPPILLRPGFIDKNDLSEILPDLQEMKSLDKNSYTTPISPGLKYKHYSPNCKVIFKN
SLKGIPKEFAQIGFHFESNSVYQVLVSSNKEYMKEIYSFFVECDRRGITEAWCEIPKEEKWKEVLINRISKAASK

Sequences:

>Translated_315_residues
MSENKVNTLITDSTSEAAKILLKGGLVVFPTETVYGIGASAFDIDACKRIYKVKNRPSDNPLILHVANFSSLKDCGEIDD
RANLVFQKLSPGPITGIFKKKNQNLFTAGLDSVAIRIPSNPTALGFLKFCKIPVAAPSANFSGKPSLTKIEYILEEFIGK
VDCILKGEEPQIGIESTVVDFISKPPILLRPGFIDKNDLSEILPDLQEMKSLDKNSYTTPISPGLKYKHYSPNCKVIFKN
SLKGIPKEFAQIGFHFESNSVYQVLVSSNKEYMKEIYSFFVECDRRGITEAWCEIPKEEKWKEVLINRISKAASK
>Mature_314_residues
SENKVNTLITDSTSEAAKILLKGGLVVFPTETVYGIGASAFDIDACKRIYKVKNRPSDNPLILHVANFSSLKDCGEIDDR
ANLVFQKLSPGPITGIFKKKNQNLFTAGLDSVAIRIPSNPTALGFLKFCKIPVAAPSANFSGKPSLTKIEYILEEFIGKV
DCILKGEEPQIGIESTVVDFISKPPILLRPGFIDKNDLSEILPDLQEMKSLDKNSYTTPISPGLKYKHYSPNCKVIFKNS
LKGIPKEFAQIGFHFESNSVYQVLVSSNKEYMKEIYSFFVECDRRGITEAWCEIPKEEKWKEVLINRISKAASK

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=168, Percent_Identity=29.1666666666667, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87081864, Length=189, Percent_Identity=26.4550264550265, Blast_Score=72, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6321269, Length=249, Percent_Identity=36.144578313253, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI78707274, Length=178, Percent_Identity=25.8426966292135, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 35083; Mature: 34952

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENKVNTLITDSTSEAAKILLKGGLVVFPTETVYGIGASAFDIDACKRIYKVKNRPSDN
CCCCCCEEEEECCCHHHHHHHHHCCEEEEECCHHEECCCCCCCHHHHHHHHHHHCCCCCC
PLILHVANFSSLKDCGEIDDRANLVFQKLSPGPITGIFKKKNQNLFTAGLDSVAIRIPSN
CEEEEEECCCCHHHHHCCCHHHHHHHEECCCCCEEEEEECCCCCEEEECCCEEEEECCCC
PTALGFLKFCKIPVAAPSANFSGKPSLTKIEYILEEFIGKVDCILKGEEPQIGIESTVVD
CCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHH
FISKPPILLRPGFIDKNDLSEILPDLQEMKSLDKNSYTTPISPGLKYKHYSPNCKVIFKN
HHCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCEEEECC
SLKGIPKEFAQIGFHFESNSVYQVLVSSNKEYMKEIYSFFVECDRRGITEAWCEIPKEEK
CCCCCHHHHHHHCCEECCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHH
WKEVLINRISKAASK
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
SENKVNTLITDSTSEAAKILLKGGLVVFPTETVYGIGASAFDIDACKRIYKVKNRPSDN
CCCCCEEEEECCCHHHHHHHHHCCEEEEECCHHEECCCCCCCHHHHHHHHHHHCCCCCC
PLILHVANFSSLKDCGEIDDRANLVFQKLSPGPITGIFKKKNQNLFTAGLDSVAIRIPSN
CEEEEEECCCCHHHHHCCCHHHHHHHEECCCCCEEEEEECCCCCEEEECCCEEEEECCCC
PTALGFLKFCKIPVAAPSANFSGKPSLTKIEYILEEFIGKVDCILKGEEPQIGIESTVVD
CCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHH
FISKPPILLRPGFIDKNDLSEILPDLQEMKSLDKNSYTTPISPGLKYKHYSPNCKVIFKN
HHCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCEEEECC
SLKGIPKEFAQIGFHFESNSVYQVLVSSNKEYMKEIYSFFVECDRRGITEAWCEIPKEEK
CCCCCHHHHHHHCCEECCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHH
WKEVLINRISKAASK
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]