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The map label for this gene is mcp-2

Identifier: 45657557

GI number: 45657557

Start: 2054053

End: 2055561

Strand: Reverse

Name: mcp-2

Synonym: LIC11691

Alternate gene names: 45657557

Gene position: 2055561-2054053 (Counterclockwise)

Preceding gene: 45657563

Following gene: 45657556

Centisome position: 48.06

GC content: 35.98

Gene sequence:

>1509_bases
TTGGTCATTCTTTTTTCTCTTACATTAATCAGCGTTTCTAAAACGAATCATCCCACTCAAGTAATCGCACACGTAGCCGG
TACAACTTTAATGGGACTTTATTGTCTTTTAGAATTTATTCTTCATCGGGCCGGTAAAGTAGGAGTTCGATTTCAGAAAA
CGTTAGTTCTTTTTGATGTTAACATTCTTTCTTTAACTCTCATGGTAGATTGTTCTATCGAGCCAGAAGTATCTTCCGGC
ATACTCGCTAATATGCTTATATTCTTTATTTACTTTTACATCATGCTTTATTCGTCTTTTTTAGGTGAAAAGAAATTCAT
ACTTCTGGTTGGTGTTTTTTCTGCGTTAGGCATCATTACTTCAGTTTTTGTAGCTTGGAAAGGTGGTATGATTCTCACAG
AAGATCCAGAAATAGGTAAAAATCCAGGTAGCCTGATATTTTCCGTCCAGATCATTAAAGTTACCTTCGTATTTACTGCC
AGTGTGATTCTTTTTCATTTGATGAAACTTTTTGATAAACTTACTACAGAAGGTTCAAGGCTTTACGAAGATTCTCAACA
CCTCTTAAAGAAACTCACTCAGGATCGTGAAGTATTGGAAAATTCAGCTGAAAATTTGGAATCTTCAATTCGTAAGTTCG
CGGAATTTATCAATCGAACCGGAGAAAAGATGGAATCCCAAGCTGCTGCTATCGAAGAAGTCAACGCAGTGATTGAAGAA
CTTTCCGTTTCCTCTTCAAACACTACACATTCTATCGAAACCCAGAATTTGAGTTTAAGCGAACTTGTTGGCAATTCAGA
AAAGTTAGACGAAATCTTAAAAAACAGCGCTTCTCTAAGTGAAGCTCTCGCCATTTTTGCTAAAGAGAATAAAATAGATA
TGGAAAACGTAACGATCGCTGCAGAAAAAACAAAATCCTATCTCATGGATATTTCGAATTCGTTTAACAAAGTAGACGAA
ATCAATCGAATTATGAGTGAAATTGCAGATAAAACTAACCTGCTTGCTCTGAATGCTTCGATCGAAGCCGCAAGGGCAGG
TGTAGCCGGAAGAGGGTTTGCAGTAGTCGCAAATGAAGTAAGTAAACTTGCAGAATTTACTTCCAGTAATGCCAAATCTA
TTTCTGAAATTGTCAATCAGTCCAGAAAATTTATTGAAGAGGCAAGAATTGCATCTACAGAAACTGGAAATCTGACGGAA
AATCAGAAGATGAAAAATTTAGATACCGCAGATCGAATCGATAAGATGAATCAGTTCTATCTAGAGCAAAAATCAATTAT
CCAAAAATTTGTCTCAGAAGTGAATCGAATTAAATTGACTTCTGAAAAAATTCTCAGATCTACTCAGGAGCAAATGTTGG
GACAAAAAGAGATGGTTCAGACGATGGGAAATTTAGGTTCTGAAATCAATCAAATCAACGAAGATTCGGGACAACTCCAA
GAGGAAATTGTAAGAATTAAAACCCAAGCTTCTGAACTTAGACTTTTAAGTATTCAATCTGAAAGTTGA

Upstream 100 bases:

>100_bases
TAGGAGCATTCTCATGCAGAATCCAATCCAATCCGAAAAATCTTCCATCCATCAGATTTGGAAAGAAGGTGCCGTAGTTA
TCAATCGAATTCGTTTCGGA

Downstream 100 bases:

>100_bases
TTTCGAAATTTTAAAAAATATTTTTTATCCTTTTTAAAATCGATTCTGTAAATTCCTATAAAATAGTATACCAAGGATTT
TGAGGCAATTTATGAGTTCT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MVILFSLTLISVSKTNHPTQVIAHVAGTTLMGLYCLLEFILHRAGKVGVRFQKTLVLFDVNILSLTLMVDCSIEPEVSSG
ILANMLIFFIYFYIMLYSSFLGEKKFILLVGVFSALGIITSVFVAWKGGMILTEDPEIGKNPGSLIFSVQIIKVTFVFTA
SVILFHLMKLFDKLTTEGSRLYEDSQHLLKKLTQDREVLENSAENLESSIRKFAEFINRTGEKMESQAAAIEEVNAVIEE
LSVSSSNTTHSIETQNLSLSELVGNSEKLDEILKNSASLSEALAIFAKENKIDMENVTIAAEKTKSYLMDISNSFNKVDE
INRIMSEIADKTNLLALNASIEAARAGVAGRGFAVVANEVSKLAEFTSSNAKSISEIVNQSRKFIEEARIASTETGNLTE
NQKMKNLDTADRIDKMNQFYLEQKSIIQKFVSEVNRIKLTSEKILRSTQEQMLGQKEMVQTMGNLGSEINQINEDSGQLQ
EEIVRIKTQASELRLLSIQSES

Sequences:

>Translated_502_residues
MVILFSLTLISVSKTNHPTQVIAHVAGTTLMGLYCLLEFILHRAGKVGVRFQKTLVLFDVNILSLTLMVDCSIEPEVSSG
ILANMLIFFIYFYIMLYSSFLGEKKFILLVGVFSALGIITSVFVAWKGGMILTEDPEIGKNPGSLIFSVQIIKVTFVFTA
SVILFHLMKLFDKLTTEGSRLYEDSQHLLKKLTQDREVLENSAENLESSIRKFAEFINRTGEKMESQAAAIEEVNAVIEE
LSVSSSNTTHSIETQNLSLSELVGNSEKLDEILKNSASLSEALAIFAKENKIDMENVTIAAEKTKSYLMDISNSFNKVDE
INRIMSEIADKTNLLALNASIEAARAGVAGRGFAVVANEVSKLAEFTSSNAKSISEIVNQSRKFIEEARIASTETGNLTE
NQKMKNLDTADRIDKMNQFYLEQKSIIQKFVSEVNRIKLTSEKILRSTQEQMLGQKEMVQTMGNLGSEINQINEDSGQLQ
EEIVRIKTQASELRLLSIQSES
>Mature_502_residues
MVILFSLTLISVSKTNHPTQVIAHVAGTTLMGLYCLLEFILHRAGKVGVRFQKTLVLFDVNILSLTLMVDCSIEPEVSSG
ILANMLIFFIYFYIMLYSSFLGEKKFILLVGVFSALGIITSVFVAWKGGMILTEDPEIGKNPGSLIFSVQIIKVTFVFTA
SVILFHLMKLFDKLTTEGSRLYEDSQHLLKKLTQDREVLENSAENLESSIRKFAEFINRTGEKMESQAAAIEEVNAVIEE
LSVSSSNTTHSIETQNLSLSELVGNSEKLDEILKNSASLSEALAIFAKENKIDMENVTIAAEKTKSYLMDISNSFNKVDE
INRIMSEIADKTNLLALNASIEAARAGVAGRGFAVVANEVSKLAEFTSSNAKSISEIVNQSRKFIEEARIASTETGNLTE
NQKMKNLDTADRIDKMNQFYLEQKSIIQKFVSEVNRIKLTSEKILRSTQEQMLGQKEMVQTMGNLGSEINQINEDSGQLQ
EEIVRIKTQASELRLLSIQSES

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=155, Percent_Identity=32.9032258064516, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788194, Length=244, Percent_Identity=27.8688524590164, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI2367378, Length=208, Percent_Identity=30.2884615384615, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789453, Length=315, Percent_Identity=24.7619047619048, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788195, Length=150, Percent_Identity=30.6666666666667, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 55841; Mature: 55841

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVILFSLTLISVSKTNHPTQVIAHVAGTTLMGLYCLLEFILHRAGKVGVRFQKTLVLFDV
CEEEEEEEEHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHEEEEEEH
NILSLTLMVDCSIEPEVSSGILANMLIFFIYFYIMLYSSFLGEKKFILLVGVFSALGIIT
HHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
SVFVAWKGGMILTEDPEIGKNPGSLIFSVQIIKVTFVFTASVILFHLMKLFDKLTTEGSR
HHHHHHCCCEEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LYEDSQHLLKKLTQDREVLENSAENLESSIRKFAEFINRTGEKMESQAAAIEEVNAVIEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSVSSSNTTHSIETQNLSLSELVGNSEKLDEILKNSASLSEALAIFAKENKIDMENVTIA
HHCCCCCCCCEEEECCCCHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEE
AEKTKSYLMDISNSFNKVDEINRIMSEIADKTNLLALNASIEAARAGVAGRGFAVVANEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHCCCCCCCHHHHHHHH
SKLAEFTSSNAKSISEIVNQSRKFIEEARIASTETGNLTENQKMKNLDTADRIDKMNQFY
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHHH
LEQKSIIQKFVSEVNRIKLTSEKILRSTQEQMLGQKEMVQTMGNLGSEINQINEDSGQLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHH
EEIVRIKTQASELRLLSIQSES
HHHHHHHHHHHHEEEEEECCCC
>Mature Secondary Structure
MVILFSLTLISVSKTNHPTQVIAHVAGTTLMGLYCLLEFILHRAGKVGVRFQKTLVLFDV
CEEEEEEEEHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHEEEEEEH
NILSLTLMVDCSIEPEVSSGILANMLIFFIYFYIMLYSSFLGEKKFILLVGVFSALGIIT
HHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
SVFVAWKGGMILTEDPEIGKNPGSLIFSVQIIKVTFVFTASVILFHLMKLFDKLTTEGSR
HHHHHHCCCEEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LYEDSQHLLKKLTQDREVLENSAENLESSIRKFAEFINRTGEKMESQAAAIEEVNAVIEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSVSSSNTTHSIETQNLSLSELVGNSEKLDEILKNSASLSEALAIFAKENKIDMENVTIA
HHCCCCCCCCEEEECCCCHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEE
AEKTKSYLMDISNSFNKVDEINRIMSEIADKTNLLALNASIEAARAGVAGRGFAVVANEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHCCCCCCCHHHHHHHH
SKLAEFTSSNAKSISEIVNQSRKFIEEARIASTETGNLTENQKMKNLDTADRIDKMNQFY
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHHH
LEQKSIIQKFVSEVNRIKLTSEKILRSTQEQMLGQKEMVQTMGNLGSEINQINEDSGQLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHH
EEIVRIKTQASELRLLSIQSES
HHHHHHHHHHHHEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]