| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
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The map label for this gene is fabG
Identifier: 45657490
GI number: 45657490
Start: 1980115
End: 1980885
Strand: Reverse
Name: fabG
Synonym: LIC11618
Alternate gene names: 45657490
Gene position: 1980885-1980115 (Counterclockwise)
Preceding gene: 45657491
Following gene: 45657489
Centisome position: 46.31
GC content: 37.87
Gene sequence:
>771_bases TTGGATATTAAAGGTAAAACAGTACTCGTTACCGGTTCCGCAAGTGGTCTTGGAAAGGCGATGGCCGAACATTTCGCCAA AAAAGGGGCAAAAATCGTTCTTTCCGACATATCTGAAGAAAAACTAAAAGAAGCTGAAAAAGATATTAAAACTTTAGGAA CCGAAGTATATTCGTTTAAAGCAGATGTATCTAAAGAAGAAGATGCAGAAAAGCTTATGCAGTCTGCAGTAAAACAATTC GGAAGTTTAGACGTAGCCATATTGAATGCCGGAATTTTAAGAGACGGCTTACTCGTAAAAACGGATAAAGAAACTGGTAA AGTAATTTCTAAAATGTCTTTGTCTAACTGGCAGTCGGTCATAGACGTCAATCTCACTGGAGTATTTTTGACCGGAAGAG AAGCTGCAATCCAAATGATAGAAAGTAAAAGTAAAGGTGTTATTATCCCGATTGCATCTGTAGCGATGCACGGAAATCCA GGTCAGACAAATTATTCGGCTGCAAAGGCCGGAGTTGCCTCAATGACAAAACTATGGGCAAAAGAGTTAAGTAGATACGG CATTCGTGTGGCAGGAATTGCACCTGGTTTTATAAAAACAGAAATGGTAATGAAAGATATGAACCCCGAGGCATTAAAAA AATGGGAAGCCCTTATACCAATTGGTAGATTAGGAGAACCTTATGAAATTGCCTTCTCTGCAGACTTCATTGTTAGTAAT GATTTAGTATCAGGTGTTATATTAGAAATATCAGGTGGAGTAAAAATTTAA
Upstream 100 bases:
>100_bases CGAATTATGACCCGGGAACACGAAACGGTTTCTAGAGTAGAAATTCCATTTTCTGCAAATTATATCAGCATTAGAAGTAA AGAATTAAAGGAAAATAGTC
Downstream 100 bases:
>100_bases TCGGAAATCATTTTTTTAAGAAAAGAACTTTACATTAAGATAAAATTGTAATAAAATAGTCCATAATTTACTGAATTGAG ATTTAGTAGTTTACTAAAAT
Product: 3-ketoacyl-(acyl-carrier-protein) reductase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 256; Mature: 256
Protein sequence:
>256_residues MDIKGKTVLVTGSASGLGKAMAEHFAKKGAKIVLSDISEEKLKEAEKDIKTLGTEVYSFKADVSKEEDAEKLMQSAVKQF GSLDVAILNAGILRDGLLVKTDKETGKVISKMSLSNWQSVIDVNLTGVFLTGREAAIQMIESKSKGVIIPIASVAMHGNP GQTNYSAAKAGVASMTKLWAKELSRYGIRVAGIAPGFIKTEMVMKDMNPEALKKWEALIPIGRLGEPYEIAFSADFIVSN DLVSGVILEISGGVKI
Sequences:
>Translated_256_residues MDIKGKTVLVTGSASGLGKAMAEHFAKKGAKIVLSDISEEKLKEAEKDIKTLGTEVYSFKADVSKEEDAEKLMQSAVKQF GSLDVAILNAGILRDGLLVKTDKETGKVISKMSLSNWQSVIDVNLTGVFLTGREAAIQMIESKSKGVIIPIASVAMHGNP GQTNYSAAKAGVASMTKLWAKELSRYGIRVAGIAPGFIKTEMVMKDMNPEALKKWEALIPIGRLGEPYEIAFSADFIVSN DLVSGVILEISGGVKI >Mature_256_residues MDIKGKTVLVTGSASGLGKAMAEHFAKKGAKIVLSDISEEKLKEAEKDIKTLGTEVYSFKADVSKEEDAEKLMQSAVKQF GSLDVAILNAGILRDGLLVKTDKETGKVISKMSLSNWQSVIDVNLTGVFLTGREAAIQMIESKSKGVIIPIASVAMHGNP GQTNYSAAKAGVASMTKLWAKELSRYGIRVAGIAPGFIKTEMVMKDMNPEALKKWEALIPIGRLGEPYEIAFSADFIVSN DLVSGVILEISGGVKI
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=252, Percent_Identity=35.3174603174603, Blast_Score=141, Evalue=6e-34, Organism=Homo sapiens, GI15277342, Length=263, Percent_Identity=33.8403041825095, Blast_Score=137, Evalue=1e-32, Organism=Homo sapiens, GI4758504, Length=262, Percent_Identity=35.1145038167939, Blast_Score=124, Evalue=7e-29, Organism=Homo sapiens, GI83715985, Length=262, Percent_Identity=32.4427480916031, Blast_Score=104, Evalue=7e-23, Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=29.0196078431373, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI4504505, Length=230, Percent_Identity=32.1739130434783, Blast_Score=98, Evalue=8e-21, Organism=Homo sapiens, GI19923817, Length=264, Percent_Identity=26.1363636363636, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI59889578, Length=242, Percent_Identity=28.9256198347107, Blast_Score=88, Evalue=6e-18, Organism=Homo sapiens, GI5031737, Length=242, Percent_Identity=27.6859504132231, Blast_Score=82, Evalue=3e-16, Organism=Homo sapiens, GI126723750, Length=256, Percent_Identity=28.125, Blast_Score=82, Evalue=7e-16, Organism=Homo sapiens, GI31542939, Length=271, Percent_Identity=25.830258302583, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI210032110, Length=203, Percent_Identity=26.1083743842365, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI4503301, Length=237, Percent_Identity=27.0042194092827, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI109715829, Length=247, Percent_Identity=27.1255060728745, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI142976729, Length=251, Percent_Identity=25.4980079681275, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI10190704, Length=260, Percent_Identity=27.6923076923077, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI33667109, Length=208, Percent_Identity=28.8461538461538, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI209862901, Length=209, Percent_Identity=24.4019138755981, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI19923983, Length=209, Percent_Identity=24.4019138755981, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI40807363, Length=205, Percent_Identity=28.2926829268293, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI66933014, Length=260, Percent_Identity=28.8461538461538, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI31543615, Length=203, Percent_Identity=27.5862068965517, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI4557649, Length=214, Percent_Identity=27.5700934579439, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI126723191, Length=190, Percent_Identity=26.8421052631579, Blast_Score=65, Evalue=4e-11, Organism=Escherichia coli, GI1787335, Length=257, Percent_Identity=34.2412451361868, Blast_Score=134, Evalue=6e-33, Organism=Escherichia coli, GI1790717, Length=260, Percent_Identity=31.9230769230769, Blast_Score=125, Evalue=2e-30, Organism=Escherichia coli, GI87082160, Length=257, Percent_Identity=34.2412451361868, Blast_Score=125, Evalue=3e-30, Organism=Escherichia coli, GI87082100, Length=248, Percent_Identity=31.8548387096774, Blast_Score=114, Evalue=4e-27, Organism=Escherichia coli, GI1789208, Length=258, Percent_Identity=31.7829457364341, Blast_Score=114, Evalue=9e-27, Organism=Escherichia coli, GI1787905, Length=256, Percent_Identity=31.25, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI1788459, Length=255, Percent_Identity=29.4117647058824, Blast_Score=93, Evalue=1e-20, Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=27.9527559055118, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1786812, Length=263, Percent_Identity=29.6577946768061, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1789378, Length=255, Percent_Identity=27.843137254902, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1787526, Length=228, Percent_Identity=25.8771929824561, Blast_Score=77, Evalue=8e-16, Organism=Escherichia coli, GI1789057, Length=212, Percent_Identity=27.3584905660377, Blast_Score=75, Evalue=3e-15, Organism=Escherichia coli, GI1787820, Length=192, Percent_Identity=28.125, Blast_Score=71, Evalue=7e-14, Organism=Escherichia coli, GI1788891, Length=273, Percent_Identity=23.4432234432234, Blast_Score=65, Evalue=6e-12, Organism=Escherichia coli, GI2367365, Length=236, Percent_Identity=27.9661016949153, Blast_Score=63, Evalue=2e-11, Organism=Caenorhabditis elegans, GI25147288, Length=253, Percent_Identity=37.9446640316205, Blast_Score=139, Evalue=1e-33, Organism=Caenorhabditis elegans, GI17555706, Length=256, Percent_Identity=35.15625, Blast_Score=134, Evalue=3e-32, Organism=Caenorhabditis elegans, GI17562908, Length=256, Percent_Identity=29.6875, Blast_Score=110, Evalue=8e-25, Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=32.0754716981132, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17538182, Length=261, Percent_Identity=32.5670498084291, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=30, Blast_Score=107, Evalue=8e-24, Organism=Caenorhabditis elegans, GI17562904, Length=250, Percent_Identity=30, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17562906, Length=256, Percent_Identity=27.734375, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17531453, Length=256, Percent_Identity=30.46875, Blast_Score=102, Evalue=3e-22, Organism=Caenorhabditis elegans, GI193203115, Length=223, Percent_Identity=31.8385650224215, Blast_Score=100, Evalue=6e-22, Organism=Caenorhabditis elegans, GI17560676, Length=254, Percent_Identity=28.3464566929134, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17560150, Length=257, Percent_Identity=28.0155642023346, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17562990, Length=258, Percent_Identity=28.2945736434109, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17536651, Length=259, Percent_Identity=30.5019305019305, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI193204405, Length=256, Percent_Identity=27.34375, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI193203117, Length=224, Percent_Identity=31.25, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI17536025, Length=261, Percent_Identity=31.4176245210728, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17568967, Length=224, Percent_Identity=29.0178571428571, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17562910, Length=239, Percent_Identity=29.7071129707113, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17561402, Length=260, Percent_Identity=27.3076923076923, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI17563726, Length=243, Percent_Identity=32.0987654320988, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17564282, Length=223, Percent_Identity=30.4932735426009, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17538486, Length=253, Percent_Identity=26.8774703557312, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17544670, Length=271, Percent_Identity=28.0442804428044, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI72000259, Length=245, Percent_Identity=31.0204081632653, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17565030, Length=265, Percent_Identity=30.5660377358491, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI115534694, Length=256, Percent_Identity=27.734375, Blast_Score=84, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17567345, Length=216, Percent_Identity=29.1666666666667, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI32563809, Length=226, Percent_Identity=26.5486725663717, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17507613, Length=226, Percent_Identity=26.5486725663717, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI71994600, Length=260, Percent_Identity=26.9230769230769, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI71994604, Length=256, Percent_Identity=25.78125, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17561272, Length=260, Percent_Identity=30.3846153846154, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17551412, Length=250, Percent_Identity=28, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17508895, Length=205, Percent_Identity=28.780487804878, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=27.0992366412214, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17538480, Length=254, Percent_Identity=26.7716535433071, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI17508651, Length=258, Percent_Identity=27.1317829457364, Blast_Score=66, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=234, Percent_Identity=35.8974358974359, Blast_Score=111, Evalue=9e-26, Organism=Saccharomyces cerevisiae, GI6324126, Length=260, Percent_Identity=31.1538461538462, Blast_Score=90, Evalue=4e-19, Organism=Saccharomyces cerevisiae, GI6323882, Length=205, Percent_Identity=28.780487804878, Blast_Score=76, Evalue=7e-15, Organism=Saccharomyces cerevisiae, GI6320089, Length=218, Percent_Identity=26.1467889908257, Blast_Score=65, Evalue=1e-11, Organism=Drosophila melanogaster, GI24639444, Length=260, Percent_Identity=37.6923076923077, Blast_Score=144, Evalue=5e-35, Organism=Drosophila melanogaster, GI17737361, Length=262, Percent_Identity=38.1679389312977, Blast_Score=137, Evalue=5e-33, Organism=Drosophila melanogaster, GI24644339, Length=262, Percent_Identity=31.6793893129771, Blast_Score=111, Evalue=4e-25, Organism=Drosophila melanogaster, GI23397609, Length=261, Percent_Identity=30.2681992337165, Blast_Score=110, Evalue=6e-25, Organism=Drosophila melanogaster, GI21355319, Length=245, Percent_Identity=30.2040816326531, Blast_Score=105, Evalue=3e-23, Organism=Drosophila melanogaster, GI28571526, Length=260, Percent_Identity=30.7692307692308, Blast_Score=105, Evalue=3e-23, Organism=Drosophila melanogaster, GI21357041, Length=259, Percent_Identity=28.957528957529, Blast_Score=95, Evalue=5e-20, Organism=Drosophila melanogaster, GI24644337, Length=265, Percent_Identity=30.5660377358491, Blast_Score=94, Evalue=8e-20, Organism=Drosophila melanogaster, GI18859837, Length=200, Percent_Identity=32, Blast_Score=94, Evalue=8e-20, Organism=Drosophila melanogaster, GI281364892, Length=205, Percent_Identity=29.7560975609756, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI281364494, Length=215, Percent_Identity=28.8372093023256, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24640492, Length=205, Percent_Identity=28.2926829268293, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24649181, Length=204, Percent_Identity=27.9411764705882, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24641232, Length=221, Percent_Identity=24.8868778280543, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI24641388, Length=210, Percent_Identity=27.6190476190476, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI116007236, Length=209, Percent_Identity=24.8803827751196, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI24584752, Length=196, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI24643142, Length=258, Percent_Identity=25.968992248062, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24663911, Length=205, Percent_Identity=22.9268292682927, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 27378; Mature: 27378
Theoretical pI: Translated: 9.22; Mature: 9.22
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 3.9 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 3.9 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDIKGKTVLVTGSASGLGKAMAEHFAKKGAKIVLSDISEEKLKEAEKDIKTLGTEVYSFK CCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHEEE ADVSKEEDAEKLMQSAVKQFGSLDVAILNAGILRDGLLVKTDKETGKVISKMSLSNWQSV CCCCCCHHHHHHHHHHHHHHCCCEEEEEECCHHCCCEEEEECCHHHHHHHHHHHHCCHHE IDVNLTGVFLTGREAAIQMIESKSKGVIIPIASVAMHGNPGQTNYSAAKAGVASMTKLWA EEEEEEEEEEECHHHHHHHHHCCCCCEEEEEHHEEECCCCCCCCHHHHHHHHHHHHHHHH KELSRYGIRVAGIAPGFIKTEMVMKDMNPEALKKWEALIPIGRLGEPYEIAFSADFIVSN HHHHHCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEEEEEEECEEEEC DLVSGVILEISGGVKI HHHCEEEEEECCCCCC >Mature Secondary Structure MDIKGKTVLVTGSASGLGKAMAEHFAKKGAKIVLSDISEEKLKEAEKDIKTLGTEVYSFK CCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHEEE ADVSKEEDAEKLMQSAVKQFGSLDVAILNAGILRDGLLVKTDKETGKVISKMSLSNWQSV CCCCCCHHHHHHHHHHHHHHCCCEEEEEECCHHCCCEEEEECCHHHHHHHHHHHHCCHHE IDVNLTGVFLTGREAAIQMIESKSKGVIIPIASVAMHGNPGQTNYSAAKAGVASMTKLWA EEEEEEEEEEECHHHHHHHHHCCCCCEEEEEHHEEECCCCCCCCHHHHHHHHHHHHHHHH KELSRYGIRVAGIAPGFIKTEMVMKDMNPEALKKWEALIPIGRLGEPYEIAFSADFIVSN HHHHHCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEEEEEEECEEEEC DLVSGVILEISGGVKI HHHCEEEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]