Click here to switch to the map view.

The map label for this gene is cheW

Identifier: 45657395

GI number: 45657395

Start: 1881051

End: 1881566

Strand: Reverse

Name: cheW

Synonym: LIC11522

Alternate gene names: 45657395

Gene position: 1881566-1881051 (Counterclockwise)

Preceding gene: 45657396

Following gene: 45657394

Centisome position: 43.99

GC content: 32.95

Gene sequence:

>516_bases
ATGAGTGTTTTAGAAGATAATCAGTTTCTTACGTTTTATCTTGGAGAAGAATATTATGGAATTGGAATATTAAATATCAA
AGAAATTATCGAATATTCTGGTTTGACAAATGTTCCTTTAATGCCGGAATTTATTCCGGGAGTGATCAACCTTCGAGGTA
ATGTAGTTCCGGTCATAGATTTAAAACATAAATTTTTTAGAAGTAAAATAAAACCAGACCGTAAAACTTGCGTGATCATA
GTGGAATTACATTCTCAAAAAGAAGGTGATCGAAAAGAAAAAACTGACTTGGGCATTCTTGTCGAATCTGTAGACGAGGT
AGTTTCCATTCCGAACGGTGATATAGAACCTCCTCCCACCTTTGGTTCTAAAATCAAAGTAGATTTTATTTTAGGAATGG
CGAGACAGGAAAACGGTTTTATTATCATTCTGAATACTGAAAAAATTCTAAATCTGGAAGAACTAACCTCTTTAGAAGAA
AATCAGCCTTCTGAAATTGTTTTAGAAACTACATGA

Upstream 100 bases:

>100_bases
AACCGGTATTATCAAAGCGACTCCCACGACTAGAAAAGATCTTCCCAAGGGAATATCTCCCATTACCGAAAAATTCGAAA
GGTATTAAGAGGGTTTAAAG

Downstream 100 bases:

>100_bases
TATTAGAACCAGATACGGTCATAGACTTGTTTTTACAACCCGGCGGTTTTTATTGGGGAAAAGGAAATATCAGAATTAGA
ACTCTACTCGGTTCCTGTGT

Product: chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MSVLEDNQFLTFYLGEEYYGIGILNIKEIIEYSGLTNVPLMPEFIPGVINLRGNVVPVIDLKHKFFRSKIKPDRKTCVII
VELHSQKEGDRKEKTDLGILVESVDEVVSIPNGDIEPPPTFGSKIKVDFILGMARQENGFIIILNTEKILNLEELTSLEE
NQPSEIVLETT

Sequences:

>Translated_171_residues
MSVLEDNQFLTFYLGEEYYGIGILNIKEIIEYSGLTNVPLMPEFIPGVINLRGNVVPVIDLKHKFFRSKIKPDRKTCVII
VELHSQKEGDRKEKTDLGILVESVDEVVSIPNGDIEPPPTFGSKIKVDFILGMARQENGFIIILNTEKILNLEELTSLEE
NQPSEIVLETT
>Mature_170_residues
SVLEDNQFLTFYLGEEYYGIGILNIKEIIEYSGLTNVPLMPEFIPGVINLRGNVVPVIDLKHKFFRSKIKPDRKTCVIIV
ELHSQKEGDRKEKTDLGILVESVDEVVSIPNGDIEPPPTFGSKIKVDFILGMARQENGFIIILNTEKILNLEELTSLEEN
QPSEIVLETT

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=159, Percent_Identity=36.4779874213836, Blast_Score=101, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 19317; Mature: 19185

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLEDNQFLTFYLGEEYYGIGILNIKEIIEYSGLTNVPLMPEFIPGVINLRGNVVPVID
CCCCCCCCEEEEEECCCEEEEEEEEHHHHHHHCCCCCCCCCHHHCCCEEECCCCEEEEEE
LKHKFFRSKIKPDRKTCVIIVELHSQKEGDRKEKTDLGILVESVDEVVSIPNGDIEPPPT
CHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
FGSKIKVDFILGMARQENGFIIILNTEKILNLEELTSLEENQPSEIVLETT
CCCEEEEEEEEEEEECCCCEEEEECCHHHCCHHHHHHCCCCCCCEEEEEEC
>Mature Secondary Structure 
SVLEDNQFLTFYLGEEYYGIGILNIKEIIEYSGLTNVPLMPEFIPGVINLRGNVVPVID
CCCCCCCEEEEEECCCEEEEEEEEHHHHHHHCCCCCCCCCHHHCCCEEECCCCEEEEEE
LKHKFFRSKIKPDRKTCVIIVELHSQKEGDRKEKTDLGILVESVDEVVSIPNGDIEPPPT
CHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
FGSKIKVDFILGMARQENGFIIILNTEKILNLEELTSLEENQPSEIVLETT
CCCEEEEEEEEEEEECCCCEEEEECCHHHCCHHHHHHCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]