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The map label for this gene is fnr [H]

Identifier: 45657359

GI number: 45657359

Start: 1832834

End: 1833529

Strand: Reverse

Name: fnr [H]

Synonym: LIC11484

Alternate gene names: 45657359

Gene position: 1833529-1832834 (Counterclockwise)

Preceding gene: 45657362

Following gene: 45657358

Centisome position: 42.87

GC content: 34.48

Gene sequence:

>696_bases
ATGGAGATTAAAAACGAAATTCCAGATTGTTATCTTTGTCCCAATCGACATAAATTCAAATGTATATCTTTAGATACTCT
CAAAAAAATCAACTCCAGTAAAAAGTTCAGACTCTTTCGTAAAAACGAACTACTTATCCAAGAAGGAACTAAAACAAACG
GATTTTATTTTATCAAATCTGGATGTGTTCGTATATTTCGAAATTCCTCCTCTGGAAAGGAACAGACCTTTTCAATCCGA
AGAGCCGGAGAATGGGTAGGATTTAGGGATCTTTTAGCAGGAAAAACTTTTGTTCAAAATATAGAAGCCATAGAAAACGT
TGAAGCGTGTTATATTTCCAAAGAAGTTCTGAACGAATTAATGGAAGAAGATTCAAATTTTCAAATGGAAATTCTAAAAC
AAATGGCAACCGAATGGAAACAGCTAGAAGACCAAACTCTTACTTTAGGAACAAAACAAGTCCACAGTAAAATCGCTGAA
CTTCTCATTTCTTTTAGAACAACTTCCCCGGATAAATCCGAAATAGAACTCAATCTCACAAGAGAGATTATGGCTTCTAT
GGTCGGAACCTCTACCGAAACTTTGGTACGTGCTCTTTCTGATTTCAAACATAGAAAATGGATTAAAATCCGCAAAAACC
GGATTTGTTTTTTAAACGTAGACGCTTTGAAGGAAATTTCAGGCTTAAATCACTAA

Upstream 100 bases:

>100_bases
TTCTAATCACCGATAGAAAATTCTAGATTCGTTTTTTTAACCCTGATTTTATCGTCTTATCTTTTAGAGGTCAAATTTAA
CCTCTAAAATTAGAATCAAA

Downstream 100 bases:

>100_bases
TGATTCTTGTTTTACTGATTCCTATAAAATAGGATAAATTTTGATAACCCCTGTTTAAAGTTAGGTGCTCTAACGTGAAT
TCGACGCGAGTAAAAATTTT

Product: Crp family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MEIKNEIPDCYLCPNRHKFKCISLDTLKKINSSKKFRLFRKNELLIQEGTKTNGFYFIKSGCVRIFRNSSSGKEQTFSIR
RAGEWVGFRDLLAGKTFVQNIEAIENVEACYISKEVLNELMEEDSNFQMEILKQMATEWKQLEDQTLTLGTKQVHSKIAE
LLISFRTTSPDKSEIELNLTREIMASMVGTSTETLVRALSDFKHRKWIKIRKNRICFLNVDALKEISGLNH

Sequences:

>Translated_231_residues
MEIKNEIPDCYLCPNRHKFKCISLDTLKKINSSKKFRLFRKNELLIQEGTKTNGFYFIKSGCVRIFRNSSSGKEQTFSIR
RAGEWVGFRDLLAGKTFVQNIEAIENVEACYISKEVLNELMEEDSNFQMEILKQMATEWKQLEDQTLTLGTKQVHSKIAE
LLISFRTTSPDKSEIELNLTREIMASMVGTSTETLVRALSDFKHRKWIKIRKNRICFLNVDALKEISGLNH
>Mature_231_residues
MEIKNEIPDCYLCPNRHKFKCISLDTLKKINSSKKFRLFRKNELLIQEGTKTNGFYFIKSGCVRIFRNSSSGKEQTFSIR
RAGEWVGFRDLLAGKTFVQNIEAIENVEACYISKEVLNELMEEDSNFQMEILKQMATEWKQLEDQTLTLGTKQVHSKIAE
LLISFRTTSPDKSEIELNLTREIMASMVGTSTETLVRALSDFKHRKWIKIRKNRICFLNVDALKEISGLNH

Specific function: Global transcription factor that controls the expression of over 100 target genes in response to anoxia. It facilitates the adaptation to anaerobic growth conditions by regulating the expression of gene products that are involved in anaerobic energy metab

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=213, Percent_Identity=27.6995305164319, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 26796; Mature: 26796

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIKNEIPDCYLCPNRHKFKCISLDTLKKINSSKKFRLFRKNELLIQEGTKTNGFYFIKS
CCCCCCCCCEEECCCCCCEEEECHHHHHHHCCCCCEEEEECCCEEEECCCCCCCEEEEHH
GCVRIFRNSSSGKEQTFSIRRAGEWVGFRDLLAGKTFVQNIEAIENVEACYISKEVLNEL
HHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MEEDSNFQMEILKQMATEWKQLEDQTLTLGTKQVHSKIAELLISFRTTSPDKSEIELNLT
HHCCCCHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEHHH
REIMASMVGTSTETLVRALSDFKHRKWIKIRKNRICFLNVDALKEISGLNH
HHHHHHHHCCCHHHHHHHHHHHHHHHHHEEECCEEEEEEHHHHHHHCCCCC
>Mature Secondary Structure
MEIKNEIPDCYLCPNRHKFKCISLDTLKKINSSKKFRLFRKNELLIQEGTKTNGFYFIKS
CCCCCCCCCEEECCCCCCEEEECHHHHHHHCCCCCEEEEECCCEEEECCCCCCCEEEEHH
GCVRIFRNSSSGKEQTFSIRRAGEWVGFRDLLAGKTFVQNIEAIENVEACYISKEVLNEL
HHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MEEDSNFQMEILKQMATEWKQLEDQTLTLGTKQVHSKIAELLISFRTTSPDKSEIELNLT
HHCCCCHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEHHH
REIMASMVGTSTETLVRALSDFKHRKWIKIRKNRICFLNVDALKEISGLNH
HHHHHHHHCCCHHHHHHHHHHHHHHHHHEEECCEEEEEEHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA