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The map label for this gene is ykcC [H]

Identifier: 45656908

GI number: 45656908

Start: 1255359

End: 1256354

Strand: Reverse

Name: ykcC [H]

Synonym: LIC11024

Alternate gene names: 45656908

Gene position: 1256354-1255359 (Counterclockwise)

Preceding gene: 45656913

Following gene: 45656907

Centisome position: 29.37

GC content: 39.06

Gene sequence:

>996_bases
ATGGCCGAAAGACCTCCTCTCCTTTCCGTAGTCATTCCAATCTACAACGAAGAAAAAACAATTCCGGAACTTACAAAAAG
ACTTGGGGTCTTAAAAAATCTTTTGTCATCTAAACATTTTTTTCGCAAAGAAGATCTAGAAATTCTTTTTGTAAACGACG
GCTCGAGAGATGAAAGTTTTAGAGTTCTGAAAAAATTCTGCTCTCAAACGGAAGGGTATAGATTAGTCAATCTTTCCAGA
AACTATGGCCATCAAACCGCAATCACTGCAGGAATCGACACCGCTTTAGGAATTTCTGTAGCGGTGATGGACGGAGACCT
ACAAGATCCTCCCGAATTTGTATGCGATCTATATTCTAAGTTACTCGAAGGATATGACGTAGTTTATGCAAAACGAAAAA
AAAGACAGGGAGAATCTTGGTTTAAACTTTTAACCGCTCACGTATTTTATAGAATCCTAAAAGGAATCACTCGTTTTGAC
ATTCCGATCGATACTGGAGATTTTAGAATTATGAGCCGCAGGGTCACGGACGTTCTTTGTTCCATGAGAGAACAACACCG
TTATATCCGAGGACTTATCTCTTGGATCGGATTCAAACAGACAGGACTTGAATACGAAAGAGAAGAGCGTTTCGAAGGTA
GCACAAAATTTTCCGTCGCTAAAATGCTCAAGTTCGCGTTAGACGGAATCACTTCCTTCTCCTCGGCGCCCCTTAAACTT
TCTTCGTATTTAGGTTTTTTTACCGCCTTTTGTGGAGCGATATACGCGTTATACGTCATTTATCTGAAAATTTTTACTTC
CGAAACGATCACCGGTTGGAGTTCCATGATGATCGTAGTGCTTATATTAGGTGGAATACAACTTCTTGCGTTAGGTATGA
TCGGCGAATATTTAAGTAGAGTAAACGACGAATCTAAAAACAGACCTTTATACGTGATCGAAAACGTCTATTCTACCAAT
TTTCAAAAACAAAAGACTAAGAAGAGAAAATCCTAA

Upstream 100 bases:

>100_bases
AAAAATGACGATAAAAACCTTTGAATCGATAGTTTGTTAGAAACGCTGGGAATATTTCTGGACAAAAAGTCCACTCCTGT
GATTCTTACGGTTACATATT

Downstream 100 bases:

>100_bases
ACGTTTCCGGATTTTCCACTCTGGAGCTGAATATGAAAAAATACAAATCCCTAATCCCAGGCATTTTGTTGTGTTTGTTT
GCCTTGGGTCTTACGTTTTA

Product: glycosyltransferase

Products: GDP; dolichyl D-mannosyl phosphate

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MAERPPLLSVVIPIYNEEKTIPELTKRLGVLKNLLSSKHFFRKEDLEILFVNDGSRDESFRVLKKFCSQTEGYRLVNLSR
NYGHQTAITAGIDTALGISVAVMDGDLQDPPEFVCDLYSKLLEGYDVVYAKRKKRQGESWFKLLTAHVFYRILKGITRFD
IPIDTGDFRIMSRRVTDVLCSMREQHRYIRGLISWIGFKQTGLEYEREERFEGSTKFSVAKMLKFALDGITSFSSAPLKL
SSYLGFFTAFCGAIYALYVIYLKIFTSETITGWSSMMIVVLILGGIQLLALGMIGEYLSRVNDESKNRPLYVIENVYSTN
FQKQKTKKRKS

Sequences:

>Translated_331_residues
MAERPPLLSVVIPIYNEEKTIPELTKRLGVLKNLLSSKHFFRKEDLEILFVNDGSRDESFRVLKKFCSQTEGYRLVNLSR
NYGHQTAITAGIDTALGISVAVMDGDLQDPPEFVCDLYSKLLEGYDVVYAKRKKRQGESWFKLLTAHVFYRILKGITRFD
IPIDTGDFRIMSRRVTDVLCSMREQHRYIRGLISWIGFKQTGLEYEREERFEGSTKFSVAKMLKFALDGITSFSSAPLKL
SSYLGFFTAFCGAIYALYVIYLKIFTSETITGWSSMMIVVLILGGIQLLALGMIGEYLSRVNDESKNRPLYVIENVYSTN
FQKQKTKKRKS
>Mature_330_residues
AERPPLLSVVIPIYNEEKTIPELTKRLGVLKNLLSSKHFFRKEDLEILFVNDGSRDESFRVLKKFCSQTEGYRLVNLSRN
YGHQTAITAGIDTALGISVAVMDGDLQDPPEFVCDLYSKLLEGYDVVYAKRKKRQGESWFKLLTAHVFYRILKGITRFDI
PIDTGDFRIMSRRVTDVLCSMREQHRYIRGLISWIGFKQTGLEYEREERFEGSTKFSVAKMLKFALDGITSFSSAPLKLS
SYLGFFTAFCGAIYALYVIYLKIFTSETITGWSSMMIVVLILGGIQLLALGMIGEYLSRVNDESKNRPLYVIENVYSTNF
QKQKTKKRKS

Specific function: Involved In O Antigen Modification. Catalyzes The Transfer Of The Glucose Residue From Udp-Glucose To A Lipid Carrier (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family. GtrB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788692, Length=309, Percent_Identity=36.5695792880259, Blast_Score=216, Evalue=1e-57,
Organism=Escherichia coli, GI1788588, Length=317, Percent_Identity=31.5457413249211, Blast_Score=151, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: 2.4.1.83

Molecular weight: Translated: 37952; Mature: 37820

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERPPLLSVVIPIYNEEKTIPELTKRLGVLKNLLSSKHFFRKEDLEILFVNDGSRDESF
CCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHH
RVLKKFCSQTEGYRLVNLSRNYGHQTAITAGIDTALGISVAVMDGDLQDPPEFVCDLYSK
HHHHHHHCCCCCEEEEEECCCCCCCHHHHHCCHHHHCCEEEEECCCCCCCHHHHHHHHHH
LLEGYDVVYAKRKKRQGESWFKLLTAHVFYRILKGITRFDIPIDTGDFRIMSRRVTDVLC
HHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
SMREQHRYIRGLISWIGFKQTGLEYEREERFEGSTKFSVAKMLKFALDGITSFSSAPLKL
HHHHHHHHHHHHHHHHCHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
SSYLGFFTAFCGAIYALYVIYLKIFTSETITGWSSMMIVVLILGGIQLLALGMIGEYLSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNDESKNRPLYVIENVYSTNFQKQKTKKRKS
CCCCCCCCCEEEEECHHHCCHHHHHHHHCCC
>Mature Secondary Structure 
AERPPLLSVVIPIYNEEKTIPELTKRLGVLKNLLSSKHFFRKEDLEILFVNDGSRDESF
CCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHH
RVLKKFCSQTEGYRLVNLSRNYGHQTAITAGIDTALGISVAVMDGDLQDPPEFVCDLYSK
HHHHHHHCCCCCEEEEEECCCCCCCHHHHHCCHHHHCCEEEEECCCCCCCHHHHHHHHHH
LLEGYDVVYAKRKKRQGESWFKLLTAHVFYRILKGITRFDIPIDTGDFRIMSRRVTDVLC
HHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
SMREQHRYIRGLISWIGFKQTGLEYEREERFEGSTKFSVAKMLKFALDGITSFSSAPLKL
HHHHHHHHHHHHHHHHCHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
SSYLGFFTAFCGAIYALYVIYLKIFTSETITGWSSMMIVVLILGGIQLLALGMIGEYLSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNDESKNRPLYVIENVYSTNFQKQKTKKRKS
CCCCCCCCCEEEEECHHHCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GDPmannose; dolichyl phosphate

Specific reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]