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The map label for this gene is yocS [H]

Identifier: 45656865

GI number: 45656865

Start: 1183182

End: 1184090

Strand: Reverse

Name: yocS [H]

Synonym: LIC10977

Alternate gene names: 45656865

Gene position: 1184090-1183182 (Counterclockwise)

Preceding gene: 45656866

Following gene: 45656863

Centisome position: 27.68

GC content: 35.09

Gene sequence:

>909_bases
ATGCAAGAATTGGATTCTGTTCGGATTCATTTTAATGAAAGTAATTTAGCTTTTTTGAATTTACTTTTAGGGTTGATTAT
GTACGGAATCGCCTTAGAACTTAGATTTGAAGATTTTAAATTATTAGTTGATAAACCCAGATCTTCCATTACCGGAATAC
TGTCTCAATTTATACTGTTTCCGTTTGCCACTTATCTACTCCTTTGGATTTTAAATCCTTCTCCAGGAATTGCACTTGGA
ATGCTTTTAGTAGCAGCTTGTCCAGGGGGTAACATTTCGAACTTTGTCACTCTTCTTGCAAAAGGTAATACAGCCCTTTC
CATTTCGCTTACCGCATTCTCATCTGCACTTGCTATCGTTATTACTCCGTTTAATTTTTTCTTCTGGGGAAATTTATATC
CTCCTGTACAAAATACGTTAAGAACAATTTCCCTAAACCCCTGGGATGTATTGAAAGCAATCTTAATGATATTAATAATC
CCGATCCTACTAGGTCTTTTAACAAAAAAATTTCTACCAAAAACAACCGCAAAAATCGTAATACCAATCAGAATACTTTC
AGCCATTATTTTTGCCGCATTTTTATTAATCGCACTTTTTGCAAACTTTCAGATTTTTTTGAACGTAATCTATAAAGTAT
TCCTTTACGTTTTTCTAATGAACGCTGTTGGATTTTTATTGGGATATTATTTTTCAAAGCTAATGCGTTTAGATGAAAGG
GATTCTCGTTGTATTTCCATAGAAACCGGAATTCAAAATTCGGGACTAGGACTTGTTTTGATTTTCGCGTTTTTTGAAGG
CCAGGGAAGTATGGCAATCATAGCCGCGACCTGGGGAATTTGGCACGCAATTGCAGGAGTAACTCTGGCTTGGTTTTGGT
CTAAAAAAACTTCTACTTTGAAGACTTAA

Upstream 100 bases:

>100_bases
AACGGAGACATATTAGTGATAGACAACTATTCCGTATCTCACGGAAGACATCCGTTTACCGGACCAAGGGAAATTTTTGT
AGCCTGGGCGGATTAAAACC

Downstream 100 bases:

>100_bases
ACAATATCCCATGATAGAGTTCTGAAATCTTAGGACGGATTTTAGATTTCGAAAAAAAACGATTCTCGTTCAACTTTCCT
TTTCGAATTTCCTTTTGTTT

Product: sodium bile acid symporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MQELDSVRIHFNESNLAFLNLLLGLIMYGIALELRFEDFKLLVDKPRSSITGILSQFILFPFATYLLLWILNPSPGIALG
MLLVAACPGGNISNFVTLLAKGNTALSISLTAFSSALAIVITPFNFFFWGNLYPPVQNTLRTISLNPWDVLKAILMILII
PILLGLLTKKFLPKTTAKIVIPIRILSAIIFAAFLLIALFANFQIFLNVIYKVFLYVFLMNAVGFLLGYYFSKLMRLDER
DSRCISIETGIQNSGLGLVLIFAFFEGQGSMAIIAATWGIWHAIAGVTLAWFWSKKTSTLKT

Sequences:

>Translated_302_residues
MQELDSVRIHFNESNLAFLNLLLGLIMYGIALELRFEDFKLLVDKPRSSITGILSQFILFPFATYLLLWILNPSPGIALG
MLLVAACPGGNISNFVTLLAKGNTALSISLTAFSSALAIVITPFNFFFWGNLYPPVQNTLRTISLNPWDVLKAILMILII
PILLGLLTKKFLPKTTAKIVIPIRILSAIIFAAFLLIALFANFQIFLNVIYKVFLYVFLMNAVGFLLGYYFSKLMRLDER
DSRCISIETGIQNSGLGLVLIFAFFEGQGSMAIIAATWGIWHAIAGVTLAWFWSKKTSTLKT
>Mature_302_residues
MQELDSVRIHFNESNLAFLNLLLGLIMYGIALELRFEDFKLLVDKPRSSITGILSQFILFPFATYLLLWILNPSPGIALG
MLLVAACPGGNISNFVTLLAKGNTALSISLTAFSSALAIVITPFNFFFWGNLYPPVQNTLRTISLNPWDVLKAILMILII
PILLGLLTKKFLPKTTAKIVIPIRILSAIIFAAFLLIALFANFQIFLNVIYKVFLYVFLMNAVGFLLGYYFSKLMRLDER
DSRCISIETGIQNSGLGLVLIFAFFEGQGSMAIIAATWGIWHAIAGVTLAWFWSKKTSTLKT

Specific function: Unknown

COG id: COG0385

COG function: function code R; Predicted Na+-dependent transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:bile acid symporter family [H]

Homologues:

Organism=Homo sapiens, GI215422370, Length=234, Percent_Identity=27.7777777777778, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI9790143, Length=234, Percent_Identity=27.7777777777778, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI215422368, Length=234, Percent_Identity=27.7777777777778, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI4506973, Length=238, Percent_Identity=24.3697478991597, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI37537552, Length=234, Percent_Identity=26.4957264957265, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI58219066, Length=260, Percent_Identity=27.3076923076923, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI4506971, Length=237, Percent_Identity=26.5822784810127, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI24308414, Length=259, Percent_Identity=26.6409266409266, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI18859699, Length=247, Percent_Identity=25.5060728744939, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004710
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 33618; Mature: 33618

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQELDSVRIHFNESNLAFLNLLLGLIMYGIALELRFEDFKLLVDKPRSSITGILSQFILF
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHEEEHHHHHHHHCCCHHHHHHHHHHHHHH
PFATYLLLWILNPSPGIALGMLLVAACPGGNISNFVTLLAKGNTALSISLTAFSSALAIV
HHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHEECCCCEEEEEHHHHHCCCEEE
ITPFNFFFWGNLYPPVQNTLRTISLNPWDVLKAILMILIIPILLGLLTKKFLPKTTAKIV
EECHHHEEECCCCCHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
IPIRILSAIIFAAFLLIALFANFQIFLNVIYKVFLYVFLMNAVGFLLGYYFSKLMRLDER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DSRCISIETGIQNSGLGLVLIFAFFEGQGSMAIIAATWGIWHAIAGVTLAWFWSKKTSTL
CCCEEEEECCCCCCCCHHEEEEEHHCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCC
KT
CC
>Mature Secondary Structure
MQELDSVRIHFNESNLAFLNLLLGLIMYGIALELRFEDFKLLVDKPRSSITGILSQFILF
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHEEEHHHHHHHHCCCHHHHHHHHHHHHHH
PFATYLLLWILNPSPGIALGMLLVAACPGGNISNFVTLLAKGNTALSISLTAFSSALAIV
HHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHEECCCCEEEEEHHHHHCCCEEE
ITPFNFFFWGNLYPPVQNTLRTISLNPWDVLKAILMILIIPILLGLLTKKFLPKTTAKIV
EECHHHEEECCCCCHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
IPIRILSAIIFAAFLLIALFANFQIFLNVIYKVFLYVFLMNAVGFLLGYYFSKLMRLDER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DSRCISIETGIQNSGLGLVLIFAFFEGQGSMAIIAATWGIWHAIAGVTLAWFWSKKTSTL
CCCEEEEECCCCCCCCHHEEEEEHHCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCC
KT
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]