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The map label for this gene is yheS [H]

Identifier: 45656836

GI number: 45656836

Start: 1141562

End: 1143058

Strand: Reverse

Name: yheS [H]

Synonym: LIC10948

Alternate gene names: 45656836

Gene position: 1143058-1141562 (Counterclockwise)

Preceding gene: 45656837

Following gene: 45656835

Centisome position: 26.72

GC content: 39.21

Gene sequence:

>1497_bases
ATGATAAAAATTTCCGGCCTAAACAAGGCATTTACAACCAAAGTTCTTTTTGACGACTTGAACCTGAGCATCAATCGAGG
AGAAAAAGTCGGACTCGTAGGTCGCAACGGACACGGAAAGTCTACGCTTTTTCAGGTAATACTTGGAAACGTGGAAGCGG
ATTCAGGAACGATTTCGATTCCTAAGGGATATAAGATCGGACATCTACAACAACATCTTCATTTTACTAAACCAACTGTA
CTAGAGGAATGTTCTCTTGGACTTCCAGAGGGAGAAGAATACGAAACCTGGAAGGTCGAAAAAATTCTTTCCGGTTTGGG
CTTTTCCGAACAGGACATGGAAAAAAATCCAAACGAGTTTTCCGGAGGTTATCAGATTCGGATGAATCTTGCAAAACTTC
TAGTTTCTTCGCCCGACATGCTGATGTTAGACGAACCCAATAACTATCTAGATATAGTTACGATCCGTTGGCTCGAAGAA
TTTTTAAGAGAATGGGAAGGTGAAATCATATTAGTAACTCATGATAGAGGATTTATGGACGCAGTGGTCACTCATACAAT
TGCGATTCATAGAACCAAGGCAATCAAGGTTCAAGGTGATACAGATAAACTTTACAACCAGATCAATCAATCCGAAGAGA
TCTACGAAAAGACTCGTTTAAACGAAGCGAAAAAACGCAAACAAGAAGAGATATTCATCGCAAAATTTAAAGCAAAGGCG
AGTTTTGCGAGCCGAGCCCAATCCAGAGTCAAAAAATTAGAAAAACAAGGAGAGATGAAAGAGCTTGAGAAAATTCAAGA
TTTGGAATTATATTTCAACAGTGCTCCATTTAACGCAAATCAAATGTTATCCGCAGAAAATCTTTCCTTTTCCTATGACG
ATAAGGAACCGTTTCTGATAGAAAACTTTTCCATCAGCGTAGGCAGCAGAGAAAGAATTTGTATCATTGGTAAAAACGGA
AAAGGGAAATCCACTCTTCTCAAAATTTTAGCGGGAGAATTAGAAACCTCTCAAGGAACGATCAAAAAACATCCAGTTTT
AAAAGAAGGTTATTTTGGCCAGACCAACAAACTCAATCTAAACGAAAATTCCACGGTCGTAGAAGAAATTATGATTTCCG
ATCCATCCTGCAACGAATGGAAGGCCAGAACGATCGCAGGTGGATTGATGTTTTCAGAAGATCAAGCTTTGAAAAAAATC
AAAGTACTTTCTGGAGGTGAAAAAAGCAGGGTGCTTCTCGGAAAAATATTAGTGACTCCTTGTCATCTACTTTATCTGGA
CGAACCTACAAACCATTTAGATATGCAATCCTGCGATTCTCTTATCGAAGCCATCGATGAATTCGACGGCTCTGTCATTA
TGGTGACTCACGACGAACTACATCTCCGCGCAGTCGCCACAAAATTGATTGTATTTGATAACGATTCGATTCAAATTTTC
AACGGTTCATATGACGATTTTCTAAACGACGTTGGCTGGTCTAACGAACATTATTAA

Upstream 100 bases:

>100_bases
AAAAAGAATAACATAATACGGCAGAGATTCGACTTTTCAAATCAAATATAGATCACATTTAGAATGACCCTTGTATCGTG
TCTGAAATTTTGGTTTTCAG

Downstream 100 bases:

>100_bases
ATTAAAATATTATTTTATGTAAAAATAAAGTTTAATAAAGGTGAAATTATCGATTCTACTCCAAGTAGAATGATTTTATT
ACTCGGAAGATATAATATAA

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MIKISGLNKAFTTKVLFDDLNLSINRGEKVGLVGRNGHGKSTLFQVILGNVEADSGTISIPKGYKIGHLQQHLHFTKPTV
LEECSLGLPEGEEYETWKVEKILSGLGFSEQDMEKNPNEFSGGYQIRMNLAKLLVSSPDMLMLDEPNNYLDIVTIRWLEE
FLREWEGEIILVTHDRGFMDAVVTHTIAIHRTKAIKVQGDTDKLYNQINQSEEIYEKTRLNEAKKRKQEEIFIAKFKAKA
SFASRAQSRVKKLEKQGEMKELEKIQDLELYFNSAPFNANQMLSAENLSFSYDDKEPFLIENFSISVGSRERICIIGKNG
KGKSTLLKILAGELETSQGTIKKHPVLKEGYFGQTNKLNLNENSTVVEEIMISDPSCNEWKARTIAGGLMFSEDQALKKI
KVLSGGEKSRVLLGKILVTPCHLLYLDEPTNHLDMQSCDSLIEAIDEFDGSVIMVTHDELHLRAVATKLIVFDNDSIQIF
NGSYDDFLNDVGWSNEHY

Sequences:

>Translated_498_residues
MIKISGLNKAFTTKVLFDDLNLSINRGEKVGLVGRNGHGKSTLFQVILGNVEADSGTISIPKGYKIGHLQQHLHFTKPTV
LEECSLGLPEGEEYETWKVEKILSGLGFSEQDMEKNPNEFSGGYQIRMNLAKLLVSSPDMLMLDEPNNYLDIVTIRWLEE
FLREWEGEIILVTHDRGFMDAVVTHTIAIHRTKAIKVQGDTDKLYNQINQSEEIYEKTRLNEAKKRKQEEIFIAKFKAKA
SFASRAQSRVKKLEKQGEMKELEKIQDLELYFNSAPFNANQMLSAENLSFSYDDKEPFLIENFSISVGSRERICIIGKNG
KGKSTLLKILAGELETSQGTIKKHPVLKEGYFGQTNKLNLNENSTVVEEIMISDPSCNEWKARTIAGGLMFSEDQALKKI
KVLSGGEKSRVLLGKILVTPCHLLYLDEPTNHLDMQSCDSLIEAIDEFDGSVIMVTHDELHLRAVATKLIVFDNDSIQIF
NGSYDDFLNDVGWSNEHY
>Mature_498_residues
MIKISGLNKAFTTKVLFDDLNLSINRGEKVGLVGRNGHGKSTLFQVILGNVEADSGTISIPKGYKIGHLQQHLHFTKPTV
LEECSLGLPEGEEYETWKVEKILSGLGFSEQDMEKNPNEFSGGYQIRMNLAKLLVSSPDMLMLDEPNNYLDIVTIRWLEE
FLREWEGEIILVTHDRGFMDAVVTHTIAIHRTKAIKVQGDTDKLYNQINQSEEIYEKTRLNEAKKRKQEEIFIAKFKAKA
SFASRAQSRVKKLEKQGEMKELEKIQDLELYFNSAPFNANQMLSAENLSFSYDDKEPFLIENFSISVGSRERICIIGKNG
KGKSTLLKILAGELETSQGTIKKHPVLKEGYFGQTNKLNLNENSTVVEEIMISDPSCNEWKARTIAGGLMFSEDQALKKI
KVLSGGEKSRVLLGKILVTPCHLLYLDEPTNHLDMQSCDSLIEAIDEFDGSVIMVTHDELHLRAVATKLIVFDNDSIQIF
NGSYDDFLNDVGWSNEHY

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=529, Percent_Identity=31.9470699432892, Blast_Score=270, Evalue=2e-72,
Organism=Homo sapiens, GI27881506, Length=528, Percent_Identity=32.3863636363636, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI10947137, Length=528, Percent_Identity=32.3863636363636, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI69354671, Length=538, Percent_Identity=29.368029739777, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI10947135, Length=538, Percent_Identity=29.368029739777, Blast_Score=187, Evalue=2e-47,
Organism=Escherichia coli, GI1789751, Length=526, Percent_Identity=31.3688212927757, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI1787041, Length=543, Percent_Identity=31.8600368324125, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI1787182, Length=542, Percent_Identity=28.9667896678967, Blast_Score=206, Evalue=4e-54,
Organism=Escherichia coli, GI2367384, Length=515, Percent_Identity=27.5728155339806, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1788165, Length=204, Percent_Identity=31.8627450980392, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788761, Length=196, Percent_Identity=30.6122448979592, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788450, Length=198, Percent_Identity=29.7979797979798, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787370, Length=224, Percent_Identity=25.4464285714286, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI87081791, Length=229, Percent_Identity=25.764192139738, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1787029, Length=216, Percent_Identity=28.7037037037037, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1787758, Length=189, Percent_Identity=25.3968253968254, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788225, Length=236, Percent_Identity=25.4237288135593, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789890, Length=217, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787112, Length=231, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786253, Length=203, Percent_Identity=27.5862068965517, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1789672, Length=230, Percent_Identity=25.2173913043478, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI48995001, Length=221, Percent_Identity=29.8642533936652, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787164, Length=226, Percent_Identity=26.5486725663717, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790467, Length=192, Percent_Identity=29.6875, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788644, Length=124, Percent_Identity=33.8709677419355, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=534, Percent_Identity=29.2134831460674, Blast_Score=241, Evalue=9e-64,
Organism=Caenorhabditis elegans, GI17559834, Length=548, Percent_Identity=30.8394160583942, Blast_Score=234, Evalue=7e-62,
Organism=Caenorhabditis elegans, GI17555318, Length=523, Percent_Identity=29.2543021032505, Blast_Score=215, Evalue=4e-56,
Organism=Saccharomyces cerevisiae, GI6321121, Length=391, Percent_Identity=32.7365728900256, Blast_Score=237, Evalue=4e-63,
Organism=Saccharomyces cerevisiae, GI6320874, Length=540, Percent_Identity=30.1851851851852, Blast_Score=209, Evalue=8e-55,
Organism=Saccharomyces cerevisiae, GI6325030, Length=363, Percent_Identity=27.5482093663912, Blast_Score=134, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6324314, Length=352, Percent_Identity=26.1363636363636, Blast_Score=113, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6323278, Length=350, Percent_Identity=24.8571428571429, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24666836, Length=533, Percent_Identity=35.8348968105066, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI24642252, Length=533, Percent_Identity=29.8311444652908, Blast_Score=231, Evalue=1e-60,
Organism=Drosophila melanogaster, GI18859989, Length=533, Percent_Identity=29.8311444652908, Blast_Score=231, Evalue=1e-60,
Organism=Drosophila melanogaster, GI24641342, Length=541, Percent_Identity=32.3475046210721, Blast_Score=224, Evalue=1e-58,
Organism=Drosophila melanogaster, GI116007184, Length=215, Percent_Identity=29.3023255813954, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI221500365, Length=215, Percent_Identity=29.3023255813954, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28574259, Length=174, Percent_Identity=28.735632183908, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 56266; Mature: 56266

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKISGLNKAFTTKVLFDDLNLSINRGEKVGLVGRNGHGKSTLFQVILGNVEADSGTISI
CEEECCCCCHHHHEEEEECCCEEECCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCEEEC
PKGYKIGHLQQHLHFTKPTVLEECSLGLPEGEEYETWKVEKILSGLGFSEQDMEKNPNEF
CCCCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHCCCCCC
SGGYQIRMNLAKLLVSSPDMLMLDEPNNYLDIVTIRWLEEFLREWEGEIILVTHDRGFMD
CCCEEEEEEHHHHHHCCCCEEEEECCCCEEEEEEHHHHHHHHHHHCCCEEEEECCCCHHH
AVVTHTIAIHRTKAIKVQGDTDKLYNQINQSEEIYEKTRLNEAKKRKQEEIFIAKFKAKA
HHHHHHHEEEEEEEEEEECCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCEEEEEEHHHH
SFASRAQSRVKKLEKQGEMKELEKIQDLELYFNSAPFNANQMLSAENLSFSYDDKEPFLI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEECCCCCCHHHEEEECCCEEECCCCCCEEE
ENFSISVGSRERICIIGKNGKGKSTLLKILAGELETSQGTIKKHPVLKEGYFGQTNKLNL
EEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCEEEC
NENSTVVEEIMISDPSCNEWKARTIAGGLMFSEDQALKKIKVLSGGEKSRVLLGKILVTP
CCCCHHHHHHHCCCCCCCCCCHHEEECCEEECCHHHHHHHHHHCCCCCCCEEHHHHHHCC
CHLLYLDEPTNHLDMQSCDSLIEAIDEFDGSVIMVTHDELHLRAVATKLIVFDNDSIQIF
EEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHEEEEEEEEEEEECCCEEEE
NGSYDDFLNDVGWSNEHY
CCCHHHHHHHCCCCCCCC
>Mature Secondary Structure
MIKISGLNKAFTTKVLFDDLNLSINRGEKVGLVGRNGHGKSTLFQVILGNVEADSGTISI
CEEECCCCCHHHHEEEEECCCEEECCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCEEEC
PKGYKIGHLQQHLHFTKPTVLEECSLGLPEGEEYETWKVEKILSGLGFSEQDMEKNPNEF
CCCCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHCCCCCC
SGGYQIRMNLAKLLVSSPDMLMLDEPNNYLDIVTIRWLEEFLREWEGEIILVTHDRGFMD
CCCEEEEEEHHHHHHCCCCEEEEECCCCEEEEEEHHHHHHHHHHHCCCEEEEECCCCHHH
AVVTHTIAIHRTKAIKVQGDTDKLYNQINQSEEIYEKTRLNEAKKRKQEEIFIAKFKAKA
HHHHHHHEEEEEEEEEEECCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCEEEEEEHHHH
SFASRAQSRVKKLEKQGEMKELEKIQDLELYFNSAPFNANQMLSAENLSFSYDDKEPFLI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEECCCCCCHHHEEEECCCEEECCCCCCEEE
ENFSISVGSRERICIIGKNGKGKSTLLKILAGELETSQGTIKKHPVLKEGYFGQTNKLNL
EEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCEEEC
NENSTVVEEIMISDPSCNEWKARTIAGGLMFSEDQALKKIKVLSGGEKSRVLLGKILVTP
CCCCHHHHHHHCCCCCCCCCCHHEEECCEEECCHHHHHHHHHHCCCCCCCEEHHHHHHCC
CHLLYLDEPTNHLDMQSCDSLIEAIDEFDGSVIMVTHDELHLRAVATKLIVFDNDSIQIF
EEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHEEEEEEEEEEEECCCEEEE
NGSYDDFLNDVGWSNEHY
CCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]