Click here to switch to the map view.

The map label for this gene is cutA

Identifier: 45656489

GI number: 45656489

Start: 722043

End: 722363

Strand: Reverse

Name: cutA

Synonym: LIC10591

Alternate gene names: 45656489

Gene position: 722363-722043 (Counterclockwise)

Preceding gene: 45656494

Following gene: 45656488

Centisome position: 16.89

GC content: 36.76

Gene sequence:

>321_bases
ATGGAAGCGAGACTTGTTTACGTTACGACGAGCAACGAAAAGGAAGCACTTAAAATCGGCAAGACTCTCGTGGAAGAAAG
ACTGGCCGCCTGTGCAAATATTATCCCTAAAATGAAATCAATTTATCATTGGGAGGATAAATTAATAGAAGAAAATGAAG
CCATTTTAATTCTGAAATCGAAAAGCGAATTGATGACGGAAGTAATTTTAAGGGTCAAATCCTTACACAGTTATTCCGTT
CCTTGTATAGTAAGCCTACCTTTATTAGAAGGAAATAAGGATTATTTTTCATGGATCTACAGCGAAGTGCTCGCAGATTA
A

Upstream 100 bases:

>100_bases
TTAAAACATAAGGAAAGTGTAAAAAACTTTCCAAAAAATACGAATTTAGGACGAAATTTAAAACTGAATTTCCGATTTAT
TTACGTTAAGGAGAATCCCA

Downstream 100 bases:

>100_bases
AATACATTCAAAAAAGGTTATATTTTGCAATTTCACGTTAAACAAAAATTTACGGCTCTTACATTTAACTCGGCATTTTT
TGGCTTTTACGCACATGCAG

Product: periplasmic divalent cation tolerance

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 106; Mature: 106

Protein sequence:

>106_residues
MEARLVYVTTSNEKEALKIGKTLVEERLAACANIIPKMKSIYHWEDKLIEENEAILILKSKSELMTEVILRVKSLHSYSV
PCIVSLPLLEGNKDYFSWIYSEVLAD

Sequences:

>Translated_106_residues
MEARLVYVTTSNEKEALKIGKTLVEERLAACANIIPKMKSIYHWEDKLIEENEAILILKSKSELMTEVILRVKSLHSYSV
PCIVSLPLLEGNKDYFSWIYSEVLAD
>Mature_106_residues
MEARLVYVTTSNEKEALKIGKTLVEERLAACANIIPKMKSIYHWEDKLIEENEAILILKSKSELMTEVILRVKSLHSYSV
PCIVSLPLLEGNKDYFSWIYSEVLAD

Specific function: Involved in resistance toward heavy metals [H]

COG id: COG1324

COG function: function code P; Uncharacterized protein involved in tolerance to divalent cations

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutA family [H]

Homologues:

Organism=Homo sapiens, GI62526024, Length=93, Percent_Identity=40.8602150537634, Blast_Score=89, Evalue=7e-19,
Organism=Homo sapiens, GI62526022, Length=93, Percent_Identity=40.8602150537634, Blast_Score=89, Evalue=7e-19,
Organism=Homo sapiens, GI7706244, Length=93, Percent_Identity=40.8602150537634, Blast_Score=89, Evalue=7e-19,
Organism=Homo sapiens, GI62526026, Length=93, Percent_Identity=40.8602150537634, Blast_Score=89, Evalue=8e-19,
Organism=Homo sapiens, GI62198241, Length=93, Percent_Identity=40.8602150537634, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1790579, Length=95, Percent_Identity=36.8421052631579, Blast_Score=73, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI32565476, Length=95, Percent_Identity=37.8947368421053, Blast_Score=81, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24641937, Length=99, Percent_Identity=35.3535353535354, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004323
- InterPro:   IPR011322 [H]

Pfam domain/function: PF03091 CutA1 [H]

EC number: NA

Molecular weight: Translated: 12145; Mature: 12145

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEARLVYVTTSNEKEALKIGKTLVEERLAACANIIPKMKSIYHWEDKLIEENEAILILKS
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
KSELMTEVILRVKSLHSYSVPCIVSLPLLEGNKDYFSWIYSEVLAD
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MEARLVYVTTSNEKEALKIGKTLVEERLAACANIIPKMKSIYHWEDKLIEENEAILILKS
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
KSELMTEVILRVKSLHSYSVPCIVSLPLLEGNKDYFSWIYSEVLAD
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA