| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
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The map label for this gene is pbpB
Identifier: 45656426
GI number: 45656426
Start: 637791
End: 639599
Strand: Direct
Name: pbpB
Synonym: LIC10528
Alternate gene names: 45656426
Gene position: 637791-639599 (Clockwise)
Preceding gene: 45656417
Following gene: 45656427
Centisome position: 14.91
GC content: 38.25
Gene sequence:
>1809_bases ATGAATTCCCGTAAAACTAGACTCACGATTTTATTTTCCTTTCTTTGTATTTTATTTTGTGTGCTAATTGGAAGAGTCAT CTTTCTCACGTTTTGGAATGAACGAGAAGTAGTTCTAAAAACTGGAGATAGAATCATGAGAGGTGCTATCTACGATCGAA GGGGAATTGAACTCGCGATGACAGTAGATTCGGCAACGATCGGAATTTATCCAGCAAATATCTACGATCCAAATTTTACC GCAGTTCAATTGGCTCCTTATTTGGATATGTCTGCCGAAAAAATCGAAGCTATGATTCGAGAAAAGAGCCGCTATTTTCT TTTAAAGAGAGAAATCGACGAATCTCTTGGTAACAAAATTATGGATCTCGCACTTCCAGGTGTAAGAAGGGAAAAGGAAT ACAAACGAGTTTATCCACATGGCAATCTCGCTTCCAGTTTGATTGGTTTTACAGGAATGGATGACGACCGGGCGCTTTCC GGTTTGGAAGTTCAATACAATCAAGACTTAATGACTCCAACTGAATCTGATTCGTCTAGGGGCAGTAATTTACACCTAAC AATTGATGGTTTGATTCAGTATAAGCTTGAAAAGGCTCTCGGAAAAAGATTCGAAGAAACCGGCTCTAAAAAAGCTATCG GGATTTTAATGGAAATCAATACCGGAAAAGTTCTCGCTTCTGCTTCCTTTCCTGCTTTCGATCCAAATCAATATAACGAA TCGGGGGAAGATTCTCATACAAACTGGGCAATTCGTCACGTCTACGAACCAGGCTCTACGATGAAAATTTTTTTGGCATC TGTACTATTCAATGAAAATCTAATACGTTCGGATGAAAAATTTCATTGTCCCGGATATGTGGAATTTGGAAAAATAAAGA TCAAATGTACAGAAGCTCACGGACACTTGAATTTAGAAGAGATCCTTCAATATTCCTGCAATGTTGGGATTATCAAAGCT TCCCAAAAAATTCCAGAAACATTACTTTATGATTATATGAAAAAATTTCAATTTGGAGAAAAAACAGGATTTCTACCAAA CGAATCTGTAGGTTATTTTCCTCCTTTGAAAAAATGGACTCCCGCGACTTCTATGTTTATGGCAATTGGTCAAGGGATTT CCGTGACACCGATTCAATTGGTTGCTTCGGCGGCTTCTGTTGTCAACGGAGGAAGGATGTTGATTCCTAGAGTGGTTTCT CATTTCAGCGATTCTTACGGAGAAATTCTTCATGAGTTTAAAACTCAAGAAACTCCGATTGGAATTAGAGACTATACTAC GGAAAAAATTCTTAGAGCGATGACTAGAGTGGTTCAATCTGGAACTGGAAAAAACGCTTATATTCAGGAATACTCAATTG CTGGTAAAACTGGAACTGGTCAAAAAGCTGTTTCCGGAAAAGGTTATGTGGAGGGTTTGTGGTCCGCTTCTTTTTTAGGA TTTTTTCCGGCGGAACGACCTAAGATTGTAGGTTTGATTCTTTTTGACGAACCGAAAGGTGGAACTCATTCCGGAGGTGG ATTGGCCGCTCCGGTTTTTAAAGAAGTTGTAGAAAATATCATTCCAATTATTGAGCAAGGAGAAAGAACCTTAAACGTTT CTTTAAAACGTTTTCAAAGGAAAAACACAAAGACGACTAACGTGGATGGAATTCCAGATTTAATTGGAAAAAGCAAACGA GAAGTTTTAGAAATAGTAAGACCTCTTGGGATTTCGGTTAAATTTCATGGAAGCGGGTTTTGTTACGAGCAGGAACCCGC TCCTGGAAAAAAAATCGAAAACGGAAGACTTAATTTATATTTTAAGTAA
Upstream 100 bases:
>100_bases TATGTTATATAGTTTTGAGTAGTGATCTTAAATTATTCGATTACAACTTCAAAACAGCTCTTTTCAAAATTTAAGTTTTG GCCGATCTTGTAAGAAGAGA
Downstream 100 bases:
>100_bases ATAATATATTCTAAAATTATGATTTATTCGACTTCGTCGGTTCTTGAAAAAAACTTAAAAAGTTTATCCGTTGTCTTTCC TTCGATACGGGAAAAAGTTC
Product: Pbp3
Products: NA
Alternate protein names: Sporulation-specific penicillin-binding protein [H]
Number of amino acids: Translated: 602; Mature: 602
Protein sequence:
>602_residues MNSRKTRLTILFSFLCILFCVLIGRVIFLTFWNEREVVLKTGDRIMRGAIYDRRGIELAMTVDSATIGIYPANIYDPNFT AVQLAPYLDMSAEKIEAMIREKSRYFLLKREIDESLGNKIMDLALPGVRREKEYKRVYPHGNLASSLIGFTGMDDDRALS GLEVQYNQDLMTPTESDSSRGSNLHLTIDGLIQYKLEKALGKRFEETGSKKAIGILMEINTGKVLASASFPAFDPNQYNE SGEDSHTNWAIRHVYEPGSTMKIFLASVLFNENLIRSDEKFHCPGYVEFGKIKIKCTEAHGHLNLEEILQYSCNVGIIKA SQKIPETLLYDYMKKFQFGEKTGFLPNESVGYFPPLKKWTPATSMFMAIGQGISVTPIQLVASAASVVNGGRMLIPRVVS HFSDSYGEILHEFKTQETPIGIRDYTTEKILRAMTRVVQSGTGKNAYIQEYSIAGKTGTGQKAVSGKGYVEGLWSASFLG FFPAERPKIVGLILFDEPKGGTHSGGGLAAPVFKEVVENIIPIIEQGERTLNVSLKRFQRKNTKTTNVDGIPDLIGKSKR EVLEIVRPLGISVKFHGSGFCYEQEPAPGKKIENGRLNLYFK
Sequences:
>Translated_602_residues MNSRKTRLTILFSFLCILFCVLIGRVIFLTFWNEREVVLKTGDRIMRGAIYDRRGIELAMTVDSATIGIYPANIYDPNFT AVQLAPYLDMSAEKIEAMIREKSRYFLLKREIDESLGNKIMDLALPGVRREKEYKRVYPHGNLASSLIGFTGMDDDRALS GLEVQYNQDLMTPTESDSSRGSNLHLTIDGLIQYKLEKALGKRFEETGSKKAIGILMEINTGKVLASASFPAFDPNQYNE SGEDSHTNWAIRHVYEPGSTMKIFLASVLFNENLIRSDEKFHCPGYVEFGKIKIKCTEAHGHLNLEEILQYSCNVGIIKA SQKIPETLLYDYMKKFQFGEKTGFLPNESVGYFPPLKKWTPATSMFMAIGQGISVTPIQLVASAASVVNGGRMLIPRVVS HFSDSYGEILHEFKTQETPIGIRDYTTEKILRAMTRVVQSGTGKNAYIQEYSIAGKTGTGQKAVSGKGYVEGLWSASFLG FFPAERPKIVGLILFDEPKGGTHSGGGLAAPVFKEVVENIIPIIEQGERTLNVSLKRFQRKNTKTTNVDGIPDLIGKSKR EVLEIVRPLGISVKFHGSGFCYEQEPAPGKKIENGRLNLYFK >Mature_602_residues MNSRKTRLTILFSFLCILFCVLIGRVIFLTFWNEREVVLKTGDRIMRGAIYDRRGIELAMTVDSATIGIYPANIYDPNFT AVQLAPYLDMSAEKIEAMIREKSRYFLLKREIDESLGNKIMDLALPGVRREKEYKRVYPHGNLASSLIGFTGMDDDRALS GLEVQYNQDLMTPTESDSSRGSNLHLTIDGLIQYKLEKALGKRFEETGSKKAIGILMEINTGKVLASASFPAFDPNQYNE SGEDSHTNWAIRHVYEPGSTMKIFLASVLFNENLIRSDEKFHCPGYVEFGKIKIKCTEAHGHLNLEEILQYSCNVGIIKA SQKIPETLLYDYMKKFQFGEKTGFLPNESVGYFPPLKKWTPATSMFMAIGQGISVTPIQLVASAASVVNGGRMLIPRVVS HFSDSYGEILHEFKTQETPIGIRDYTTEKILRAMTRVVQSGTGKNAYIQEYSIAGKTGTGQKAVSGKGYVEGLWSASFLG FFPAERPKIVGLILFDEPKGGTHSGGGLAAPVFKEVVENIIPIIEQGERTLNVSLKRFQRKNTKTTNVDGIPDLIGKSKR EVLEIVRPLGISVKFHGSGFCYEQEPAPGKKIENGRLNLYFK
Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]
COG id: COG0768
COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2
Gene ontology:
Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PASTA domain [H]
Homologues:
Organism=Escherichia coli, GI1786272, Length=570, Percent_Identity=27.5438596491228, Blast_Score=198, Evalue=7e-52, Organism=Escherichia coli, GI1786854, Length=490, Percent_Identity=24.2857142857143, Blast_Score=101, Evalue=1e-22,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR005543 - InterPro: IPR005311 - InterPro: IPR001460 - InterPro: IPR011927 [H]
Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]
EC number: NA
Molecular weight: Translated: 67239; Mature: 67239
Theoretical pI: Translated: 9.04; Mature: 9.04
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.0 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 1.0 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNSRKTRLTILFSFLCILFCVLIGRVIFLTFWNEREVVLKTGDRIMRGAIYDRRGIELAM CCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCCHHHHHHHCCCCCCEEEE TVDSATIGIYPANIYDPNFTAVQLAPYLDMSAEKIEAMIREKSRYFLLKREIDESLGNKI EECCEEEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHH MDLALPGVRREKEYKRVYPHGNLASSLIGFTGMDDDRALSGLEVQYNQDLMTPTESDSSR HHHHCCCCCCCHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCC GSNLHLTIDGLIQYKLEKALGKRFEETGSKKAIGILMEINTGKVLASASFPAFDPNQYNE CCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEECCCCCCCCCCCCC SGEDSHTNWAIRHVYEPGSTMKIFLASVLFNENLIRSDEKFHCPGYVEFGKIKIKCTEAH CCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCHHHCCCCCCCCCCEEEECEEEEEEECCC GHLNLEEILQYSCNVGIIKASQKIPETLLYDYMKKFQFGEKTGFLPNESVGYFPPLKKWT CCCCHHHHHHHHCCCEEEECCHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC PATSMFMAIGQGISVTPIQLVASAASVVNGGRMLIPRVVSHFSDSYGEILHEFKTQETPI CHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEHHHHHHHHHCCHHHHHHHHHCCCCCCC GIRDYTTEKILRAMTRVVQSGTGKNAYIQEYSIAGKTGTGQKAVSGKGYVEGLWSASFLG CCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHH FFPAERPKIVGLILFDEPKGGTHSGGGLAAPVFKEVVENIIPIIEQGERTLNVSLKRFQR CCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHH KNTKTTNVDGIPDLIGKSKREVLEIVRPLGISVKFHGSGFCYEQEPAPGKKIENGRLNLY CCCCCCCCCCCHHHHCCCHHHHHHHHHHCCCEEEECCCEEEECCCCCCCCCCCCCEEEEE FK EC >Mature Secondary Structure MNSRKTRLTILFSFLCILFCVLIGRVIFLTFWNEREVVLKTGDRIMRGAIYDRRGIELAM CCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCCHHHHHHHCCCCCCEEEE TVDSATIGIYPANIYDPNFTAVQLAPYLDMSAEKIEAMIREKSRYFLLKREIDESLGNKI EECCEEEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHH MDLALPGVRREKEYKRVYPHGNLASSLIGFTGMDDDRALSGLEVQYNQDLMTPTESDSSR HHHHCCCCCCCHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCC GSNLHLTIDGLIQYKLEKALGKRFEETGSKKAIGILMEINTGKVLASASFPAFDPNQYNE CCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEECCCCCCCCCCCCC SGEDSHTNWAIRHVYEPGSTMKIFLASVLFNENLIRSDEKFHCPGYVEFGKIKIKCTEAH CCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCHHHCCCCCCCCCCEEEECEEEEEEECCC GHLNLEEILQYSCNVGIIKASQKIPETLLYDYMKKFQFGEKTGFLPNESVGYFPPLKKWT CCCCHHHHHHHHCCCEEEECCHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC PATSMFMAIGQGISVTPIQLVASAASVVNGGRMLIPRVVSHFSDSYGEILHEFKTQETPI CHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEHHHHHHHHHCCHHHHHHHHHCCCCCCC GIRDYTTEKILRAMTRVVQSGTGKNAYIQEYSIAGKTGTGQKAVSGKGYVEGLWSASFLG CCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHH FFPAERPKIVGLILFDEPKGGTHSGGGLAAPVFKEVVENIIPIIEQGERTLNVSLKRFQR CCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHH KNTKTTNVDGIPDLIGKSKREVLEIVRPLGISVKFHGSGFCYEQEPAPGKKIENGRLNLY CCCCCCCCCCCHHHHCCCHHHHHHHHHHCCCEEEECCCEEEECCCCCCCCCCCCCEEEEE FK EC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 8289242; 9384377; 8244929; 8436954 [H]