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The map label for this gene is tdh [H]

Identifier: 45656314

GI number: 45656314

Start: 472108

End: 473565

Strand: Direct

Name: tdh [H]

Synonym: LIC10414

Alternate gene names: 45656314

Gene position: 472108-473565 (Clockwise)

Preceding gene: 45656313

Following gene: 45656316

Centisome position: 11.04

GC content: 37.52

Gene sequence:

>1458_bases
TTGAAAATTTGGAATGAAAGAAAGGGGAAGCAGAACATGAAGATCGAATTTTCGGCGATGGATTATCGTTCGGATGAAAC
TTTTGAAAAAGCGAATTATCTATTCAAAGGAAGTCTGGAAAAAGGCTGGGAAATATATAGAAACGGAAAAGAGTATTTGT
GCCTCGGCCCAGGATATAAACTATTAAGGACCAAACTTTGCGGAGTTTGTTCTACAGATCTTTCCAGAAGTTTTCTTCCT
TTCCCACTTCCTCAAGTGATTGGACATGAAGTAATTGCAGAAGATATGGAGTCAATCCATGGACTTAAACAAAAATACGT
AGTAGAGATCAATGATACATTCGAAGCGAGAGGAGAAAAACCTTTCGACAAATTTTGTGAGGAAGGAATTGCATCTCATA
GTCCTACAAGAAAAGTACTCGGAATCGATAGACTTCCTGGAGGATTTGGACCTTATATTTTAGCACCACAAAATGCAGCG
ATTTCTTATCATACACTTTCTGATAAGGTTGCGGTTTTAATAGAACCATTTGCGGCTTCTTTACAAGCGGTACTATCTTC
TCCACCTAAAGATGGGGATGAGGTTGCGGTTTTAGGGCCGAGAAGATTAGGAAGTCTCGTAGTAGCCGCGTTAGCCGCTT
TTCGAAATTCTTCGGGAACTCGATTTAAAATTTCAGCACTTTCTAGACGGGATCATCTCTTAAAACTTTCTTTCAAGTTA
GGAGCGGATCAAATGATCGATTTGGGAAAAGAAAAAATAGAAACTCTTGATAAACGTTATACAATTGTTTACGATACAAC
CGGAACTACAAGTGGCTTTGAAAGTGCGATTCGGCTTACAAGTAGAGAATTACATCTAAAAACCACGAACGGGCAAGAAG
TTTTTGGGATTAAAAAGTTAACGGAGTTGGTGGTGGACGAACTTAGTCTTTTAAAATTCGCTGATGAAAATTTAAACTTT
TGTTGGGAAAAAGAAAATCGTTCCAATCGGACTGTATATGTAGCACCTAATGTTGGAAAGGTGACTTTACCTTCACATTT
CAAAGTATATTACGGTAAAATTGAGGACGCCGAAAAAATACTATCGACTGAAGATTTTCGAGGACGAATTCCTCGTTTCG
ATTTGGGAATTGCAGGTACTGTAGAGGAGATAGATCGTTTGATTCGTCCAAGTCGAAGTCATGAAAATTCTTTGATACGT
CCGAGAGGAGCTATCCTTTTCCAGGGAAAATCGGAAAAAAATTATATATTAGAATTTTTGAATTCTGGAAAGTCAATTCG
TTCGTCCCGATGCGGAGATTTTCAACTTGCAATCAAGCTATTACAGGAAAACAAAAAAATTTCAGAAGCGCTTGAAAAGA
ATATGGTAACCCATTTTTATTCACCTGAAGATTTGAATCAGGCGTTTAAAACCGCTAAAAGTTCGGAATCAATCAAAGTA
GTAATTAAACATTTCTAA

Upstream 100 bases:

>100_bases
GTCGCATGTGGGAACTACCACGGTTCGAGATTTTACAGATCAATTTAGAAAATGTGGGAACTACTACTTTCTCAATAACT
GGGTGAAGATTTAGATCTTC

Downstream 100 bases:

>100_bases
TGCTTTCGAGTAAACTTAACGTGAATTTGTAGTAGTTCCTACAATTTTGAGGTTTTGGGATGAAGTATTCAGCCGTGAAT
CTTAAAATTTGTGTTAGTTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MKIWNERKGKQNMKIEFSAMDYRSDETFEKANYLFKGSLEKGWEIYRNGKEYLCLGPGYKLLRTKLCGVCSTDLSRSFLP
FPLPQVIGHEVIAEDMESIHGLKQKYVVEINDTFEARGEKPFDKFCEEGIASHSPTRKVLGIDRLPGGFGPYILAPQNAA
ISYHTLSDKVAVLIEPFAASLQAVLSSPPKDGDEVAVLGPRRLGSLVVAALAAFRNSSGTRFKISALSRRDHLLKLSFKL
GADQMIDLGKEKIETLDKRYTIVYDTTGTTSGFESAIRLTSRELHLKTTNGQEVFGIKKLTELVVDELSLLKFADENLNF
CWEKENRSNRTVYVAPNVGKVTLPSHFKVYYGKIEDAEKILSTEDFRGRIPRFDLGIAGTVEEIDRLIRPSRSHENSLIR
PRGAILFQGKSEKNYILEFLNSGKSIRSSRCGDFQLAIKLLQENKKISEALEKNMVTHFYSPEDLNQAFKTAKSSESIKV
VIKHF

Sequences:

>Translated_485_residues
MKIWNERKGKQNMKIEFSAMDYRSDETFEKANYLFKGSLEKGWEIYRNGKEYLCLGPGYKLLRTKLCGVCSTDLSRSFLP
FPLPQVIGHEVIAEDMESIHGLKQKYVVEINDTFEARGEKPFDKFCEEGIASHSPTRKVLGIDRLPGGFGPYILAPQNAA
ISYHTLSDKVAVLIEPFAASLQAVLSSPPKDGDEVAVLGPRRLGSLVVAALAAFRNSSGTRFKISALSRRDHLLKLSFKL
GADQMIDLGKEKIETLDKRYTIVYDTTGTTSGFESAIRLTSRELHLKTTNGQEVFGIKKLTELVVDELSLLKFADENLNF
CWEKENRSNRTVYVAPNVGKVTLPSHFKVYYGKIEDAEKILSTEDFRGRIPRFDLGIAGTVEEIDRLIRPSRSHENSLIR
PRGAILFQGKSEKNYILEFLNSGKSIRSSRCGDFQLAIKLLQENKKISEALEKNMVTHFYSPEDLNQAFKTAKSSESIKV
VIKHF
>Mature_485_residues
MKIWNERKGKQNMKIEFSAMDYRSDETFEKANYLFKGSLEKGWEIYRNGKEYLCLGPGYKLLRTKLCGVCSTDLSRSFLP
FPLPQVIGHEVIAEDMESIHGLKQKYVVEINDTFEARGEKPFDKFCEEGIASHSPTRKVLGIDRLPGGFGPYILAPQNAA
ISYHTLSDKVAVLIEPFAASLQAVLSSPPKDGDEVAVLGPRRLGSLVVAALAAFRNSSGTRFKISALSRRDHLLKLSFKL
GADQMIDLGKEKIETLDKRYTIVYDTTGTTSGFESAIRLTSRELHLKTTNGQEVFGIKKLTELVVDELSLLKFADENLNF
CWEKENRSNRTVYVAPNVGKVTLPSHFKVYYGKIEDAEKILSTEDFRGRIPRFDLGIAGTVEEIDRLIRPSRSHENSLIR
PRGAILFQGKSEKNYILEFLNSGKSIRSSRCGDFQLAIKLLQENKKISEALEKNMVTHFYSPEDLNQAFKTAKSSESIKV
VIKHF

Specific function: Not Known; Probable Catabolic Enzyme. [C]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR004627
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.103 [H]

Molecular weight: Translated: 54683; Mature: 54683

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIWNERKGKQNMKIEFSAMDYRSDETFEKANYLFKGSLEKGWEIYRNGKEYLCLGPGYK
CCCCCCCCCCCCCEEEEEEECCCCCCHHHHHCCEEECCCHHHHHHHHCCCCEEEECCCHH
LLRTKLCGVCSTDLSRSFLPFPLPQVIGHEVIAEDMESIHGLKQKYVVEINDTFEARGEK
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHCCCCC
PFDKFCEEGIASHSPTRKVLGIDRLPGGFGPYILAPQNAAISYHTLSDKVAVLIEPFAAS
CHHHHHHHHHCCCCCCHHHEECCCCCCCCCCEEECCCCCEEEEEECCCCEEEEEHHHHHH
LQAVLSSPPKDGDEVAVLGPRRLGSLVVAALAAFRNSSGTRFKISALSRRDHLLKLSFKL
HHHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEECC
GADQMIDLGKEKIETLDKRYTIVYDTTGTTSGFESAIRLTSRELHLKTTNGQEVFGIKKL
CCHHHHHCCHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCEEHHHHHH
TELVVDELSLLKFADENLNFCWEKENRSNRTVYVAPNVGKVTLPSHFKVYYGKIEDAEKI
HHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEECCCCCEEECCCCEEEEECCHHHHHHH
LSTEDFRGRIPRFDLGIAGTVEEIDRLIRPSRSHENSLIRPRGAILFQGKSEKNYILEFL
HCCCCCCCCCCEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHH
NSGKSIRSSRCGDFQLAIKLLQENKKISEALEKNMVTHFYSPEDLNQAFKTAKSSESIKV
HCCCHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEE
VIKHF
EEECC
>Mature Secondary Structure
MKIWNERKGKQNMKIEFSAMDYRSDETFEKANYLFKGSLEKGWEIYRNGKEYLCLGPGYK
CCCCCCCCCCCCCEEEEEEECCCCCCHHHHHCCEEECCCHHHHHHHHCCCCEEEECCCHH
LLRTKLCGVCSTDLSRSFLPFPLPQVIGHEVIAEDMESIHGLKQKYVVEINDTFEARGEK
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHCCCCC
PFDKFCEEGIASHSPTRKVLGIDRLPGGFGPYILAPQNAAISYHTLSDKVAVLIEPFAAS
CHHHHHHHHHCCCCCCHHHEECCCCCCCCCCEEECCCCCEEEEEECCCCEEEEEHHHHHH
LQAVLSSPPKDGDEVAVLGPRRLGSLVVAALAAFRNSSGTRFKISALSRRDHLLKLSFKL
HHHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEECC
GADQMIDLGKEKIETLDKRYTIVYDTTGTTSGFESAIRLTSRELHLKTTNGQEVFGIKKL
CCHHHHHCCHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCEEHHHHHH
TELVVDELSLLKFADENLNFCWEKENRSNRTVYVAPNVGKVTLPSHFKVYYGKIEDAEKI
HHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEECCCCCEEECCCCEEEEECCHHHHHHH
LSTEDFRGRIPRFDLGIAGTVEEIDRLIRPSRSHENSLIRPRGAILFQGKSEKNYILEFL
HCCCCCCCCCCEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHH
NSGKSIRSSRCGDFQLAIKLLQENKKISEALEKNMVTHFYSPEDLNQAFKTAKSSESIKV
HCCCHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEE
VIKHF
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA