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The map label for this gene is ribH

Identifier: 45656303

GI number: 45656303

Start: 459910

End: 460365

Strand: Direct

Name: ribH

Synonym: LIC10403

Alternate gene names: 45656303

Gene position: 459910-460365 (Clockwise)

Preceding gene: 45656301

Following gene: 45656304

Centisome position: 10.75

GC content: 45.83

Gene sequence:

>456_bases
ATGATCCAAGAACTCAAAGCAGATCTAAACGGAAAGGGACAAAAACACTGTGTGATTGTCTCTCGTTTCAATGAATTTAT
AACGGAAAGTTTACTGAAAGGAGCACTTGAGTCGTTTCGGATGCACGGAGTTGAAGACGTAACCGTGGTTCGGGTTCCTG
GTGCTTACGAGATGCCGGTGGTGGTTTCTAAAGCGGCCGCTTCTAAAAAATATGATTCCATCGTTTGTTTGGGGGCGGTG
ATCCGAGGTGCAACCGCTCATTTTGATTTAGTAGCGGGAGAATCTGCAAAAATCGGATCAATTGGAGTTCAACATTCTAT
CCCTGTTATTTTTGGAGTTTTGACCACAGATACGATTGAACAAGCGATTGAAAGAGCCGGGACTAAGGCGGGAAATAAGG
GTGCGGAAGCCGCAGCCACCGCCGTGGAAATGGTAAACCTACTTTCCCTTCTTTGA

Upstream 100 bases:

>100_bases
CCTTGACTATAATATTAGGACAAAATGTCCTAATATAGATATTTTAACTTACCACAATGGTAAGATGTGATTTCTCAACA
ATAGAATCAATCAGGAATCT

Downstream 100 bases:

>100_bases
ATGTCAGCTAGACGTACTTCCAGAGAAATTGCCGTAATGGCGCTTTACCAATTGGAACTTACTCAACCCCCTTTAAAGGA
AGTTCTTAAGTTTAAATGGT

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MIQELKADLNGKGQKHCVIVSRFNEFITESLLKGALESFRMHGVEDVTVVRVPGAYEMPVVVSKAAASKKYDSIVCLGAV
IRGATAHFDLVAGESAKIGSIGVQHSIPVIFGVLTTDTIEQAIERAGTKAGNKGAEAAATAVEMVNLLSLL

Sequences:

>Translated_151_residues
MIQELKADLNGKGQKHCVIVSRFNEFITESLLKGALESFRMHGVEDVTVVRVPGAYEMPVVVSKAAASKKYDSIVCLGAV
IRGATAHFDLVAGESAKIGSIGVQHSIPVIFGVLTTDTIEQAIERAGTKAGNKGAEAAATAVEMVNLLSLL
>Mature_151_residues
MIQELKADLNGKGQKHCVIVSRFNEFITESLLKGALESFRMHGVEDVTVVRVPGAYEMPVVVSKAAASKKYDSIVCLGAV
IRGATAHFDLVAGESAKIGSIGVQHSIPVIFGVLTTDTIEQAIERAGTKAGNKGAEAAATAVEMVNLLSLL

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=148, Percent_Identity=51.3513513513513, Blast_Score=150, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6324429, Length=140, Percent_Identity=36.4285714285714, Blast_Score=81, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 15895; Mature: 15895

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQELKADLNGKGQKHCVIVSRFNEFITESLLKGALESFRMHGVEDVTVVRVPGAYEMPV
CCCHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCH
VVSKAAASKKYDSIVCLGAVIRGATAHFDLVAGESAKIGSIGVQHSIPVIFGVLTTDTIE
HHHHHHHCCCHHHHHHHHHHHHCCCHHEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHH
QAIERAGTKAGNKGAEAAATAVEMVNLLSLL
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MIQELKADLNGKGQKHCVIVSRFNEFITESLLKGALESFRMHGVEDVTVVRVPGAYEMPV
CCCHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCH
VVSKAAASKKYDSIVCLGAVIRGATAHFDLVAGESAKIGSIGVQHSIPVIFGVLTTDTIE
HHHHHHHCCCHHHHHHHHHHHHCCCHHEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHH
QAIERAGTKAGNKGAEAAATAVEMVNLLSLL
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA