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The map label for this gene is qorA [H]

Identifier: 45656186

GI number: 45656186

Start: 321233

End: 322255

Strand: Direct

Name: qorA [H]

Synonym: LIC10282

Alternate gene names: 45656186

Gene position: 321233-322255 (Clockwise)

Preceding gene: 45656185

Following gene: 45656187

Centisome position: 7.51

GC content: 37.34

Gene sequence:

>1023_bases
ATGCAAAGAACGATCGCACTTGTCCAAAAAAAAGGATCTCTTGAAAACATAAGTTTAGAAACGGAAGCTCTTCCCGAGCC
GAATGAAAACGAAGTACAAATCGAAGTTCATTCAATTGGATTAAACTTTGCGGATTTATTTGCAATTCAGGGATTGTATA
GCGCTACTCCGCAAGGAGCCTTTATTCCAGGACTTGAATATTCAGGAGTGGTAATTTCTACCGGAAAAAAAGTCAAAAAC
GTAAAAAAGAAAGATAAGATTATGGGAGTCACTCGTTTTGGCGGTTATTCTTCTCATTTGAATATAGACTCCAGATACGT
TTTTAAACTTCCTTCCAAGTGGAACTTTGATCAAGGAGCTGGTTTTCTTGTTCAAGGTTTAACCGCTTATTACGCGTTAG
CTGCTTTGGGGGATCTTAAAAAAGGACAGACGGTTTTGATCCATAGTGCGGCTGGTGGGGTCGGAATTCTTGCAAACAGA
ATCGCCAAAAAATTAGGTGCGTTCACGATCGGAACGGTAGGAACTTCTTCTAAAATCGATCTTCTTAAAAAGGAAGGTTA
TGACAAACAAATTGTTCGTTCCAGTCGATTTAAAAACGATCTACAGGAATCTCTTTCCGGAACAGATTTAAATTTAGTTT
TAGAATGTATCGGTGGAAAAATCTTTCAAGAAAGTTACGAAGTTATGGCTCCGATGGGAAGAATGATCGTCTACGGCGCA
GCGGAGATGATGGGTGAAGGTAGTTCTGTAAATTGGGCAAGAATTGCTTATAAGTATTTTTCCAGACCGAAATTAGATCC
AATGAAAATGGTTTCAGATAATAAAGCCGTGATGGGATTTAATTTGATTTGGCTCTATGAAAAGGTAGAAATATTGACAA
AACATCTAAACGCTCTTGTGAAATTAAACATTTCTCCTCCTCTTATAGGTAAAACTTTTGAGTTTGATAATTTAAACGAG
GCTCTGAAATACTTTCAATCCGGTACGTCTATGGGCAAAGTAGTTTTAAAAGTTAAATCTTAA

Upstream 100 bases:

>100_bases
AAGTTTTGGGATGATGTATACTTTATTCGAATTCCGATTGAACGGAAGTTACTGAAAATTCTACTTGCTCTTTTTACTTA
AATTCTTATAACCTCCTCTC

Downstream 100 bases:

>100_bases
ACTGAATTTGATAAACGTTGGAATCTTTTAAAAAATTCTTTTAGAATTCAATTGTAGAAGATCTTTATAAATCAATTTTT
CTTTTGATGAAAATAATTTT

Product: zinc-binding dehydrogenase family protein

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MQRTIALVQKKGSLENISLETEALPEPNENEVQIEVHSIGLNFADLFAIQGLYSATPQGAFIPGLEYSGVVISTGKKVKN
VKKKDKIMGVTRFGGYSSHLNIDSRYVFKLPSKWNFDQGAGFLVQGLTAYYALAALGDLKKGQTVLIHSAAGGVGILANR
IAKKLGAFTIGTVGTSSKIDLLKKEGYDKQIVRSSRFKNDLQESLSGTDLNLVLECIGGKIFQESYEVMAPMGRMIVYGA
AEMMGEGSSVNWARIAYKYFSRPKLDPMKMVSDNKAVMGFNLIWLYEKVEILTKHLNALVKLNISPPLIGKTFEFDNLNE
ALKYFQSGTSMGKVVLKVKS

Sequences:

>Translated_340_residues
MQRTIALVQKKGSLENISLETEALPEPNENEVQIEVHSIGLNFADLFAIQGLYSATPQGAFIPGLEYSGVVISTGKKVKN
VKKKDKIMGVTRFGGYSSHLNIDSRYVFKLPSKWNFDQGAGFLVQGLTAYYALAALGDLKKGQTVLIHSAAGGVGILANR
IAKKLGAFTIGTVGTSSKIDLLKKEGYDKQIVRSSRFKNDLQESLSGTDLNLVLECIGGKIFQESYEVMAPMGRMIVYGA
AEMMGEGSSVNWARIAYKYFSRPKLDPMKMVSDNKAVMGFNLIWLYEKVEILTKHLNALVKLNISPPLIGKTFEFDNLNE
ALKYFQSGTSMGKVVLKVKS
>Mature_340_residues
MQRTIALVQKKGSLENISLETEALPEPNENEVQIEVHSIGLNFADLFAIQGLYSATPQGAFIPGLEYSGVVISTGKKVKN
VKKKDKIMGVTRFGGYSSHLNIDSRYVFKLPSKWNFDQGAGFLVQGLTAYYALAALGDLKKGQTVLIHSAAGGVGILANR
IAKKLGAFTIGTVGTSSKIDLLKKEGYDKQIVRSSRFKNDLQESLSGTDLNLVLECIGGKIFQESYEVMAPMGRMIVYGA
AEMMGEGSSVNWARIAYKYFSRPKLDPMKMVSDNKAVMGFNLIWLYEKVEILTKHLNALVKLNISPPLIGKTFEFDNLNE
ALKYFQSGTSMGKVVLKVKS

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI18379349, Length=309, Percent_Identity=30.7443365695793, Blast_Score=164, Evalue=8e-41,
Organism=Homo sapiens, GI24308257, Length=334, Percent_Identity=26.0479041916168, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI22538446, Length=332, Percent_Identity=28.0120481927711, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI22538444, Length=332, Percent_Identity=28.0120481927711, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI194239674, Length=330, Percent_Identity=25.1515151515152, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI13236495, Length=330, Percent_Identity=25.1515151515152, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI194239676, Length=166, Percent_Identity=36.144578313253, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI41872631, Length=319, Percent_Identity=26.9592476489028, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI28557745, Length=353, Percent_Identity=24.0793201133144, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI67078404, Length=219, Percent_Identity=26.4840182648402, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1790485, Length=247, Percent_Identity=34.412955465587, Blast_Score=123, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17507255, Length=246, Percent_Identity=30.0813008130081, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI212642053, Length=288, Percent_Identity=25.3472222222222, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17536829, Length=231, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6319520, Length=347, Percent_Identity=26.5129682997118, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI221330659, Length=327, Percent_Identity=22.9357798165138, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI19920632, Length=327, Percent_Identity=22.9357798165138, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24581345, Length=345, Percent_Identity=24.0579710144928, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI45550423, Length=242, Percent_Identity=23.9669421487603, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 37342; Mature: 37342

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRTIALVQKKGSLENISLETEALPEPNENEVQIEVHSIGLNFADLFAIQGLYSATPQGA
CCCHHHHHHCCCCCCCEEECCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHCCCCCC
FIPGLEYSGVVISTGKKVKNVKKKDKIMGVTRFGGYSSHLNIDSRYVFKLPSKWNFDQGA
EECCCCCCCEEEECCHHHHHHHHHHHHEEEEECCCCCCEECCCCEEEEECCCCCCCCCCC
GFLVQGLTAYYALAALGDLKKGQTVLIHSAAGGVGILANRIAKKLGAFTIGTVGTSSKID
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEECCCCCCHHH
LLKKEGYDKQIVRSSRFKNDLQESLSGTDLNLVLECIGGKIFQESYEVMAPMGRMIVYGA
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHCHHHEEEEEC
AEMMGEGSSVNWARIAYKYFSRPKLDPMKMVSDNKAVMGFNLIWLYEKVEILTKHLNALV
HHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHCCCCEEEEEEEEEHHHHHHHHHHHHHEEE
KLNISPPLIGKTFEFDNLNEALKYFQSGTSMGKVVLKVKS
EECCCCCCCCCEECCCCHHHHHHHHHCCCCCCEEEEEECC
>Mature Secondary Structure
MQRTIALVQKKGSLENISLETEALPEPNENEVQIEVHSIGLNFADLFAIQGLYSATPQGA
CCCHHHHHHCCCCCCCEEECCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHCCCCCC
FIPGLEYSGVVISTGKKVKNVKKKDKIMGVTRFGGYSSHLNIDSRYVFKLPSKWNFDQGA
EECCCCCCCEEEECCHHHHHHHHHHHHEEEEECCCCCCEECCCCEEEEECCCCCCCCCCC
GFLVQGLTAYYALAALGDLKKGQTVLIHSAAGGVGILANRIAKKLGAFTIGTVGTSSKID
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEECCCCCCHHH
LLKKEGYDKQIVRSSRFKNDLQESLSGTDLNLVLECIGGKIFQESYEVMAPMGRMIVYGA
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHCHHHEEEEEC
AEMMGEGSSVNWARIAYKYFSRPKLDPMKMVSDNKAVMGFNLIWLYEKVEILTKHLNALV
HHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHCCCCEEEEEEEEEHHHHHHHHHHHHHEEE
KLNISPPLIGKTFEFDNLNEALKYFQSGTSMGKVVLKVKS
EECCCCCCCCCEECCCCHHHHHHHHHCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]