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The map label for this gene is crp [C]

Identifier: 45656172

GI number: 45656172

Start: 305018

End: 305683

Strand: Reverse

Name: crp [C]

Synonym: LIC10268

Alternate gene names: 45656172

Gene position: 305683-305018 (Counterclockwise)

Preceding gene: 45656173

Following gene: 45656171

Centisome position: 7.15

GC content: 36.64

Gene sequence:

>666_bases
ATGGATATGATGCTCGAATCCATGTTTTCTAAATTCGGCCAGACATATGAACCGAATCAGATCATATTTTGTGAAAACGA
ACCTGGAAATAATTTTTTTCTAATTCAGTCCGGAAAGGTAAAAATCGTTAAAACGGTTCCCAACCCTACAAAAAAAGAAG
ACTACTTGATTAAGACACTCGATATTCTCGAACAAGGGGACGTTTTCGGAGAAATGGCGATTTTAGAAGAACAACCTAGG
TCTGCAACTGCAATTGCAATCTCGGAAGTAAAGGTACTGAATTTCAATCGAGCAAATTTCGAACTCTTGATGACTAAAAA
TCCTATGTTGGCACTTAAAATTCTCACAATTTTTTCCGTTAGGATTAACGACGCTAAAAGAAGACTTTTGATTCTTTTGA
TGGATGATATTCAAGGTAAGGTTGCAGACGTTTTTTTAATGTTATACGAAAAGATGCATGCTCATAGCGATTTTAAAGAG
ATCGTCTTAAACGTTTCTCAACACGATGTAGCAGAATGGTGCGCTCAACCGGTAGGCGAAGTTCAAAAGGTTTTAAATAC
TCTTTCCAAAAGCGGTAAAATCGAACTTTACGAAGACAAAATTGTTATACACAATATTGCGGACTTCCAGAGAATCGTCG
CACAAAAACGGAAACCGAATTCTTAA

Upstream 100 bases:

>100_bases
AAAGGGCAAGGATGTTATACGGTAAGGTAGCTCTTCTTCCACCTGAAAAAGACAGTATCTCCCAAAAGTCTAAACTGAAG
GCTAAGGAGATGAGTACCTA

Downstream 100 bases:

>100_bases
AAGCTCCCGTAGCTCAGGTGGACAGAGCAGAAGTTTCCTAAACTTTTGGTCGGAGGTTCGAATCCTCTCGGGGGCATTCA
ATTTAAAAAACCAAATCATT

Product: cyclic nucleotide binding protein

Products: NA

Alternate protein names: Crp/Fnr Family Transcriptional Regulator; Transcriptional Regulator; Crp/FNR Family Transcriptional Regulator; Crp Family Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Transcriptional Regulatory Protein; Catabolite Gene Activator; Transcription Regulator; Transcriptional Regulator Crp/Fnr Family Protein; Cyclic AMP Receptor Protein; FNR/CAP Family Transcriptional Regulator; CRP Family Transcriptional Regulator; Catabolite Gene Activator Protein; CAMP-Dependent Protein Kinase

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MDMMLESMFSKFGQTYEPNQIIFCENEPGNNFFLIQSGKVKIVKTVPNPTKKEDYLIKTLDILEQGDVFGEMAILEEQPR
SATAIAISEVKVLNFNRANFELLMTKNPMLALKILTIFSVRINDAKRRLLILLMDDIQGKVADVFLMLYEKMHAHSDFKE
IVLNVSQHDVAEWCAQPVGEVQKVLNTLSKSGKIELYEDKIVIHNIADFQRIVAQKRKPNS

Sequences:

>Translated_221_residues
MDMMLESMFSKFGQTYEPNQIIFCENEPGNNFFLIQSGKVKIVKTVPNPTKKEDYLIKTLDILEQGDVFGEMAILEEQPR
SATAIAISEVKVLNFNRANFELLMTKNPMLALKILTIFSVRINDAKRRLLILLMDDIQGKVADVFLMLYEKMHAHSDFKE
IVLNVSQHDVAEWCAQPVGEVQKVLNTLSKSGKIELYEDKIVIHNIADFQRIVAQKRKPNS
>Mature_221_residues
MDMMLESMFSKFGQTYEPNQIIFCENEPGNNFFLIQSGKVKIVKTVPNPTKKEDYLIKTLDILEQGDVFGEMAILEEQPR
SATAIAISEVKVLNFNRANFELLMTKNPMLALKILTIFSVRINDAKRRLLILLMDDIQGKVADVFLMLYEKMHAHSDFKE
IVLNVSQHDVAEWCAQPVGEVQKVLNTLSKSGKIELYEDKIVIHNIADFQRIVAQKRKPNS

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 25292; Mature: 25292

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00889 CNMP_BINDING_2 ; PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMMLESMFSKFGQTYEPNQIIFCENEPGNNFFLIQSGKVKIVKTVPNPTKKEDYLIKTL
CCHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCCEEEEEECCCCCCCCHHHHHHH
DILEQGDVFGEMAILEEQPRSATAIAISEVKVLNFNRANFELLMTKNPMLALKILTIFSV
HHHHCCCHHHHHHHHHCCCCCCEEEEEEEEEEEEECCCCEEEEEECCCHHHHEEEHHHHE
RINDAKRRLLILLMDDIQGKVADVFLMLYEKMHAHSDFKEIVLNVSQHDVAEWCAQPVGE
EECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHCCHHH
VQKVLNTLSKSGKIELYEDKIVIHNIADFQRIVAQKRKPNS
HHHHHHHHHCCCCEEEEECEEEEECHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDMMLESMFSKFGQTYEPNQIIFCENEPGNNFFLIQSGKVKIVKTVPNPTKKEDYLIKTL
CCHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCCEEEEEECCCCCCCCHHHHHHH
DILEQGDVFGEMAILEEQPRSATAIAISEVKVLNFNRANFELLMTKNPMLALKILTIFSV
HHHHCCCHHHHHHHHHCCCCCCEEEEEEEEEEEEECCCCEEEEEECCCHHHHEEEHHHHE
RINDAKRRLLILLMDDIQGKVADVFLMLYEKMHAHSDFKEIVLNVSQHDVAEWCAQPVGE
EECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHCCHHH
VQKVLNTLSKSGKIELYEDKIVIHNIADFQRIVAQKRKPNS
HHHHHHHHHCCCCEEEEECEEEEECHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA