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The map label for this gene is cyoB

Identifier: 45656114

GI number: 45656114

Start: 238066

End: 239670

Strand: Direct

Name: cyoB

Synonym: LIC10209

Alternate gene names: 45656114

Gene position: 238066-239670 (Clockwise)

Preceding gene: 45656113

Following gene: 45656115

Centisome position: 5.57

GC content: 41.12

Gene sequence:

>1605_bases
ATGTCTACAGCAACTGCAAGTCATACTGACAACTACCTCAACCACGAAAAGGGAATCTGGTCCTGGCTCACTACGATCGA
TCATAAACGGATCGGGATCATGTATTTCTTTGCGATTATGTCATTCTTTCTTCTGGGTGGAATTTTCGCACTTCTGGTTC
GTTTGGAACTTTTTACTCCAGGACAAACTCTTGGATTTGTAACACCGGATATTTACAATCGAATGATGACTTATCACGGG
GCCATCATGGTATTTATGGTGATCGTTCCGGGAATTCCTGCGATTTTTGGAAACTTCATTCTTCCCATTCAATTAGGAGC
AAAAGACGTAGCATTTCCAAGATTAAATTTAGCGAGCTGGTATATTTTCATGACTGGTGCTGGAATTGCGGCATTTTCAC
TTTTTACACAGAAAGTAGATACAGGTTGGACCTTTTATACACCGTATTCCATTTCTAACTCAGTTTCTAACGGTGTAATT
ATGTTGGTAATGGGTGCGTTTGTGATGGGGTTTTCTTCCATTTTAACTGGATTGAATTTCATCGTAACCACTCACAAATT
GAGAGCTCCCGGAATGACAATGAACCGAATTCCTTTGATGGTTTGGGCATTGTATGCAACTTCTATCATACAAGTTTTAG
CGACTCCAGTTCTTGCGATCACCTTACTTTTGTTAGTTGCAGAAAGAACTCTTGGTGTTGGAATTTTTGATCCGACATTG
GGAGGAGATCCGGTTCTGTTTCAACATTTCTTCTGGTTCTACTCTCACCCTGCGGTATATATCATGATTCTTCCTGCAAT
GGGTGTCATCTCCGAACTTGTAGCGACCTTTTCTAAAAAGGTGATCTTTGGATATACTGCGATTGCATATTCTTCTCTTG
CAATTGCCGCGGTTTCCTTTTTGGTTTGGGGACATCACATGTTTGTTTCCGGCCAGTCTGAGTTTGCAGGAGTTTTATTT
TCCTTTATCACAATGCTTGTGGGAGTTCCAACGGCGATTAAGTTATTTAACTGGATTTCTACGATGTATAAGGGTTCTGT
TCGTTTAGATGCACCGATGCTTTTTGCAATCGGATTTATGTTTCTATTTACGATCGGCGGTTTGACTGGAGTATTTCTCG
CTTCTACCGGAATGGATGTTCACTTTCATGACACCTACTTTGTGGTTGCCCACTTTCATTATGTGATGGTAGGGGGAACT
TTGATGGCGGTGATGGGAGCTCTGATCTATTGGTTTCCAAAAGTAACTGGGAAGATGACTTCTGACCTGTTAGGAAGAAT
TTCTTGGGTATTTATCTTTACCGGATTTAATGTAACCTTCTTTCCTCAATTTATTTTAGGATCTATGGGAATGCCTAGAC
GGTATTATGACTATCTTCCTGAATTTACTGGCCTAAACCAAATTTCCACAATAGGGTCTTGGTTGATTGGAACCGGATTT
TTGGTTGGTTTAATTGCAGTGATCCACGGCCTAATTGCAGGAAAGACGGCAGGGGATAATCCTTGGGGAGGGAAAACTCT
CGAATGGACGATTTCTTCTCCACCTACACACGAAAATTTTGAAAAAACTCCAGTAATTACAGGGGGACCTTATGAGTACC
GCTAA

Upstream 100 bases:

>100_bases
GGTTATCCACCTGCTATGCCTTCTTATCAGGGACAGCTTTCCGACGACGAAATCAACGCTCTGATCGAGTATATTAAAAC
CCTTAAATAGGAGAGGAAAT

Downstream 100 bases:

>100_bases
GCACTTTCATCATGCTCATCACTTTGAGAGTGCAGAGCATCAGTACGACGCTTCTAAACAAGGAATTTGGTTGTTTCTTG
TTACAGAAATTTTAATGTTC

Product: cytochrome c oxidase polypeptide I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 534; Mature: 533

Protein sequence:

>534_residues
MSTATASHTDNYLNHEKGIWSWLTTIDHKRIGIMYFFAIMSFFLLGGIFALLVRLELFTPGQTLGFVTPDIYNRMMTYHG
AIMVFMVIVPGIPAIFGNFILPIQLGAKDVAFPRLNLASWYIFMTGAGIAAFSLFTQKVDTGWTFYTPYSISNSVSNGVI
MLVMGAFVMGFSSILTGLNFIVTTHKLRAPGMTMNRIPLMVWALYATSIIQVLATPVLAITLLLLVAERTLGVGIFDPTL
GGDPVLFQHFFWFYSHPAVYIMILPAMGVISELVATFSKKVIFGYTAIAYSSLAIAAVSFLVWGHHMFVSGQSEFAGVLF
SFITMLVGVPTAIKLFNWISTMYKGSVRLDAPMLFAIGFMFLFTIGGLTGVFLASTGMDVHFHDTYFVVAHFHYVMVGGT
LMAVMGALIYWFPKVTGKMTSDLLGRISWVFIFTGFNVTFFPQFILGSMGMPRRYYDYLPEFTGLNQISTIGSWLIGTGF
LVGLIAVIHGLIAGKTAGDNPWGGKTLEWTISSPPTHENFEKTPVITGGPYEYR

Sequences:

>Translated_534_residues
MSTATASHTDNYLNHEKGIWSWLTTIDHKRIGIMYFFAIMSFFLLGGIFALLVRLELFTPGQTLGFVTPDIYNRMMTYHG
AIMVFMVIVPGIPAIFGNFILPIQLGAKDVAFPRLNLASWYIFMTGAGIAAFSLFTQKVDTGWTFYTPYSISNSVSNGVI
MLVMGAFVMGFSSILTGLNFIVTTHKLRAPGMTMNRIPLMVWALYATSIIQVLATPVLAITLLLLVAERTLGVGIFDPTL
GGDPVLFQHFFWFYSHPAVYIMILPAMGVISELVATFSKKVIFGYTAIAYSSLAIAAVSFLVWGHHMFVSGQSEFAGVLF
SFITMLVGVPTAIKLFNWISTMYKGSVRLDAPMLFAIGFMFLFTIGGLTGVFLASTGMDVHFHDTYFVVAHFHYVMVGGT
LMAVMGALIYWFPKVTGKMTSDLLGRISWVFIFTGFNVTFFPQFILGSMGMPRRYYDYLPEFTGLNQISTIGSWLIGTGF
LVGLIAVIHGLIAGKTAGDNPWGGKTLEWTISSPPTHENFEKTPVITGGPYEYR
>Mature_533_residues
STATASHTDNYLNHEKGIWSWLTTIDHKRIGIMYFFAIMSFFLLGGIFALLVRLELFTPGQTLGFVTPDIYNRMMTYHGA
IMVFMVIVPGIPAIFGNFILPIQLGAKDVAFPRLNLASWYIFMTGAGIAAFSLFTQKVDTGWTFYTPYSISNSVSNGVIM
LVMGAFVMGFSSILTGLNFIVTTHKLRAPGMTMNRIPLMVWALYATSIIQVLATPVLAITLLLLVAERTLGVGIFDPTLG
GDPVLFQHFFWFYSHPAVYIMILPAMGVISELVATFSKKVIFGYTAIAYSSLAIAAVSFLVWGHHMFVSGQSEFAGVLFS
FITMLVGVPTAIKLFNWISTMYKGSVRLDAPMLFAIGFMFLFTIGGLTGVFLASTGMDVHFHDTYFVVAHFHYVMVGGTL
MAVMGALIYWFPKVTGKMTSDLLGRISWVFIFTGFNVTFFPQFILGSMGMPRRYYDYLPEFTGLNQISTIGSWLIGTGFL
VGLIAVIHGLIAGKTAGDNPWGGKTLEWTISSPPTHENFEKTPVITGGPYEYR

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=505, Percent_Identity=38.019801980198, Blast_Score=347, Evalue=1e-95,
Organism=Escherichia coli, GI1786634, Length=512, Percent_Identity=38.4765625, Blast_Score=355, Evalue=4e-99,
Organism=Saccharomyces cerevisiae, GI6226519, Length=532, Percent_Identity=36.6541353383459, Blast_Score=353, Evalue=4e-98,
Organism=Saccharomyces cerevisiae, GI6226524, Length=323, Percent_Identity=35.9133126934984, Blast_Score=221, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6226523, Length=249, Percent_Identity=33.7349397590361, Blast_Score=131, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 59014; Mature: 58882

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTATASHTDNYLNHEKGIWSWLTTIDHKRIGIMYFFAIMSFFLLGGIFALLVRLELFTP
CCCCCCCCCHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GQTLGFVTPDIYNRMMTYHGAIMVFMVIVPGIPAIFGNFILPIQLGAKDVAFPRLNLASW
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEEEECCCCCCCCCCCHHEE
YIFMTGAGIAAFSLFTQKVDTGWTFYTPYSISNSVSNGVIMLVMGAFVMGFSSILTGLNF
EEEEECCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IVTTHKLRAPGMTMNRIPLMVWALYATSIIQVLATPVLAITLLLLVAERTLGVGIFDPTL
HHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCC
GGDPVLFQHFFWFYSHPAVYIMILPAMGVISELVATFSKKVIFGYTAIAYSSLAIAAVSF
CCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVWGHHMFVSGQSEFAGVLFSFITMLVGVPTAIKLFNWISTMYKGSVRLDAPMLFAIGFM
HHHHHHEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEECCHHHHHHHHH
FLFTIGGLTGVFLASTGMDVHFHDTYFVVAHFHYVMVGGTLMAVMGALIYWFPKVTGKMT
HHHHHHHHHHHHHHCCCCEEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDLLGRISWVFIFTGFNVTFFPQFILGSMGMPRRYYDYLPEFTGLNQISTIGSWLIGTGF
HHHHHHHEEEEEEECCCHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LVGLIAVIHGLIAGKTAGDNPWGGKTLEWTISSPPTHENFEKTPVITGGPYEYR
HHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEECCCCCCC
>Mature Secondary Structure 
STATASHTDNYLNHEKGIWSWLTTIDHKRIGIMYFFAIMSFFLLGGIFALLVRLELFTP
CCCCCCCCHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GQTLGFVTPDIYNRMMTYHGAIMVFMVIVPGIPAIFGNFILPIQLGAKDVAFPRLNLASW
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEEEECCCCCCCCCCCHHEE
YIFMTGAGIAAFSLFTQKVDTGWTFYTPYSISNSVSNGVIMLVMGAFVMGFSSILTGLNF
EEEEECCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IVTTHKLRAPGMTMNRIPLMVWALYATSIIQVLATPVLAITLLLLVAERTLGVGIFDPTL
HHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCC
GGDPVLFQHFFWFYSHPAVYIMILPAMGVISELVATFSKKVIFGYTAIAYSSLAIAAVSF
CCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVWGHHMFVSGQSEFAGVLFSFITMLVGVPTAIKLFNWISTMYKGSVRLDAPMLFAIGFM
HHHHHHEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEECCHHHHHHHHH
FLFTIGGLTGVFLASTGMDVHFHDTYFVVAHFHYVMVGGTLMAVMGALIYWFPKVTGKMT
HHHHHHHHHHHHHHCCCCEEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDLLGRISWVFIFTGFNVTFFPQFILGSMGMPRRYYDYLPEFTGLNQISTIGSWLIGTGF
HHHHHHHEEEEEEECCCHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LVGLIAVIHGLIAGKTAGDNPWGGKTLEWTISSPPTHENFEKTPVITGGPYEYR
HHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8399373 [H]