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The map label for this gene is mtnU [H]

Identifier: 45656098

GI number: 45656098

Start: 222390

End: 223232

Strand: Reverse

Name: mtnU [H]

Synonym: LIC10193

Alternate gene names: 45656098

Gene position: 223232-222390 (Counterclockwise)

Preceding gene: 45656099

Following gene: 45656096

Centisome position: 5.22

GC content: 37.37

Gene sequence:

>843_bases
TTGAATCCAAATGAATTAAACGTCGCTCTTATACAATGCGACCTTTCTTGGGAAAATCAGAAAGCAAACTATGAACACGT
TCGCAATTTGATCCATTCTACTTTAGAAAAAAATTCAAACAAAAAACCAGATTTGATCTTACTTCCGGAAACCTTTGCCA
CCGGATTTACGATGAGATCGGAAAGAATTGCAGAAGCAGACGAAGGCCCCACGGAAACTTTTCTACAAGAAATCGCAAAT
TTTACACGAGCTACGATCTGCGCCGGTTGGATTCGGAAAAATCAAAATGGCAAACCTTTCAACACGGTAAGTGTAGTAAA
CCCCAACGGAATTATTATATTAAGATATTCTAAAATTTATCCATTTACTTTCGGAGGAGAAAATCGTCATTACAGCGCCG
GTTCCGAAATTTTGAGTTACAACCTAAATGGCTTTAGAATTACTCCTTTTATTTGTTATGATATTCGTTTTCCGGAAATT
TTTAGAAAGGTCGCCGGAGAAACTGATATTTTTACCATACACGCTAATTGGCCGGTTCCCAGAATTCATCATTGGGAATT
AATCCTAAAAACGAGAGCAATCGAAAATCAAGCTTACATTTTTGGAGTCAACCGAATTGGTGTTGCAGGTTATAATCAAA
GTATTTCTCACAACGGTCACTCTCTTGCAGTAGCACCTAATGGAGACTTTGTGGATGCAGGAGAAGGGAATGAAACGATC
CTATTCTACAAAGCTCATAAAAATTCTATTTCGGATTATAGAAAAGATTTTCCCGTCCTTTTAGATCGTAAGGATCCGAA
TTTAATCGGAATCAAAGTAACGGAGCATTCTTCTCAAATCTAA

Upstream 100 bases:

>100_bases
AACGATTTGAAAGATTAATTAGAAATCATTTAAATTATTTGTAATTAATTTTGAGACAGGTTTTAAAAATAAGATTCCAA
AGTCATTTAAGGAGGATCAA

Downstream 100 bases:

>100_bases
GAAATCTTTCGCTTAGAGGCAAAATGGCTTCTATCTTTTCGTTTGTAAACGGATCTTTAAATTTAAGAAAATAAGATAAA
AGTTGCAACCCATAGGATTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MNPNELNVALIQCDLSWENQKANYEHVRNLIHSTLEKNSNKKPDLILLPETFATGFTMRSERIAEADEGPTETFLQEIAN
FTRATICAGWIRKNQNGKPFNTVSVVNPNGIIILRYSKIYPFTFGGENRHYSAGSEILSYNLNGFRITPFICYDIRFPEI
FRKVAGETDIFTIHANWPVPRIHHWELILKTRAIENQAYIFGVNRIGVAGYNQSISHNGHSLAVAPNGDFVDAGEGNETI
LFYKAHKNSISDYRKDFPVLLDRKDPNLIGIKVTEHSSQI

Sequences:

>Translated_280_residues
MNPNELNVALIQCDLSWENQKANYEHVRNLIHSTLEKNSNKKPDLILLPETFATGFTMRSERIAEADEGPTETFLQEIAN
FTRATICAGWIRKNQNGKPFNTVSVVNPNGIIILRYSKIYPFTFGGENRHYSAGSEILSYNLNGFRITPFICYDIRFPEI
FRKVAGETDIFTIHANWPVPRIHHWELILKTRAIENQAYIFGVNRIGVAGYNQSISHNGHSLAVAPNGDFVDAGEGNETI
LFYKAHKNSISDYRKDFPVLLDRKDPNLIGIKVTEHSSQI
>Mature_280_residues
MNPNELNVALIQCDLSWENQKANYEHVRNLIHSTLEKNSNKKPDLILLPETFATGFTMRSERIAEADEGPTETFLQEIAN
FTRATICAGWIRKNQNGKPFNTVSVVNPNGIIILRYSKIYPFTFGGENRHYSAGSEILSYNLNGFRITPFICYDIRFPEI
FRKVAGETDIFTIHANWPVPRIHHWELILKTRAIENQAYIFGVNRIGVAGYNQSISHNGHSLAVAPNGDFVDAGEGNETI
LFYKAHKNSISDYRKDFPVLLDRKDPNLIGIKVTEHSSQI

Specific function: May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway [H]

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=249, Percent_Identity=24.8995983935743, Blast_Score=78, Evalue=8e-15,
Organism=Escherichia coli, GI1786412, Length=258, Percent_Identity=30.6201550387597, Blast_Score=126, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17556280, Length=288, Percent_Identity=25, Blast_Score=78, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323383, Length=279, Percent_Identity=26.8817204301075, Blast_Score=86, Evalue=8e-18,
Organism=Drosophila melanogaster, GI21355835, Length=274, Percent_Identity=27.007299270073, Blast_Score=81, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 31810; Mature: 31810

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPNELNVALIQCDLSWENQKANYEHVRNLIHSTLEKNSNKKPDLILLPETFATGFTMRS
CCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCHHHCCEEECH
ERIAEADEGPTETFLQEIANFTRATICAGWIRKNQNGKPFNTVSVVNPNGIIILRYSKIY
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEEEEE
PFTFGGENRHYSAGSEILSYNLNGFRITPFICYDIRFPEIFRKVAGETDIFTIHANWPVP
EEEECCCCCEECCCCEEEEECCCCEEEEEEEEEECCCHHHHHHHCCCCEEEEEECCCCCC
RIHHWELILKTRAIENQAYIFGVNRIGVAGYNQSISHNGHSLAVAPNGDFVDAGEGNETI
CEEEEEEEEEEEEECCCEEEEEECEEEEECCCCCCCCCCCEEEEECCCCEEECCCCCCEE
LFYKAHKNSISDYRKDFPVLLDRKDPNLIGIKVTEHSSQI
EEEECCCCCHHHHHCCCCEEEECCCCCEEEEEEECCCCCC
>Mature Secondary Structure
MNPNELNVALIQCDLSWENQKANYEHVRNLIHSTLEKNSNKKPDLILLPETFATGFTMRS
CCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCHHHCCEEECH
ERIAEADEGPTETFLQEIANFTRATICAGWIRKNQNGKPFNTVSVVNPNGIIILRYSKIY
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEEEEE
PFTFGGENRHYSAGSEILSYNLNGFRITPFICYDIRFPEIFRKVAGETDIFTIHANWPVP
EEEECCCCCEECCCCEEEEECCCCEEEEEEEEEECCCHHHHHHHCCCCEEEEEECCCCCC
RIHHWELILKTRAIENQAYIFGVNRIGVAGYNQSISHNGHSLAVAPNGDFVDAGEGNETI
CEEEEEEEEEEEEECCCEEEEEECEEEEECCCCCCCCCCCEEEEECCCCEEECCCCCCEE
LFYKAHKNSISDYRKDFPVLLDRKDPNLIGIKVTEHSSQI
EEEECCCCCHHHHHCCCCEEEECCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12022921 [H]