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The map label for this gene is flaI [C]

Identifier: 45359238

GI number: 45359238

Start: 1615523

End: 1617163

Strand: Direct

Name: flaI [C]

Synonym: MMP1675

Alternate gene names: 45359238

Gene position: 1615523-1617163 (Clockwise)

Preceding gene: 45359237

Following gene: 45359239

Centisome position: 97.25

GC content: 35.95

Gene sequence:

>1641_bases
ATGGCTGATGATTTCAAAACTGCACAAATGAACAATCCCCATTTAAGAAATTACGTTGAAAAATTTAAAAAAACTTACAT
GAAAGTCCCAGAATTTGTTCCGAGCCTTTCAAGAGATTTTAAAGAAATAAAATATCCAAATATAATTTATCCAATAGGTG
ACCCGATATTTATCCACCTTTACGGAACCCCAAACTTAAAAACAAGATATATTGCAATAGAACCTAAATTAAACGGTTCA
GAAGAGAGAAAAAAATATTTTGACATCCTCGATAAAATATTAGAGTATGCACCATACAGCGATATTCCAGAAAACGATGA
AGAGTTTGGAAAAGTAGTTACAAAACTATTTGACATGGTTGCAAAAGTATCAAGTCAAAAAAACGAAAAGAAAAAAGGAA
TTCTGTCAAAAATAACCGATTCTGGAAAAATAAACATAAATAAAAGTGAAAGAGATAAATTCCTCTATTTATTGAAAAGA
GACTTAATCGGACTTGGAACACTTGAACCAATAAAAAGAGACCCCTACATTGAAGATATTCACGTAATTGGTGCTAAAAA
CTGCCAGCTGGTTCACAAAATCTATGATATGCTTCCATCAAACATTGAATGGGAAGATGAAGGAGACATTTCCAATTACT
TAAAAAATATGTGTGAAAGAATCGGAAGACCAGTTTCTGATGCTACACCAATTGTAGATGGTTCCTTGCCTGATGGATCA
AGGATAAACATTCTTTATTCAGGGGACGTTTCATTAAAAGGCCCTTCATTTACAATTCGTAAATTTACAGATGTTCCAAT
AAGTATTACCCAAATTATCAGCTGGGGTACGATGTCTGCACAGACTGCAGCATATCTTTGGTTATGTCTTGAATACGGAA
TGAGTATTTTTATCTGCGGGGAAACTGCATCCGGAAAAACTACCTCACTAAACGCAATTTTGCCATTTATCAAGCCTAAA
TCAAAAATATTCTCCTGTGAGGATACTTCTGAAGTAAAACCTCCAAACCCAGTTTGGCAGCAGTTATTAACTAGAGAAAG
GGGCCCTGAAGAAAGTAGGGTTACATTATTTGATCTTTTGAGAGCTGCATTAAGGTCAAGACCAAATTACATTATCGTAG
GGGAAATCAGGTCTGTCGAAGGGGCTGTTGCGTTCCAGGCAATGCAGACCGGTCACCCGGTAATTTCAACATTCCACGCT
GCAAACGTTAGAAAAATGATACAGAGGCTTACAGGGGACCCGATATGTATTCCACAAACATTTATGGATAACTTAAACGT
CTGTCTGTTCCAGCTTGCAGTTTATGCTAGAGGAAAATTCTTAAGAAGAGTTGTTTCAGTTGAGGAAATCGAAGGATACT
ACAAGGAAGTTGATGGAGTTATTACAAGAGGTGTTTTTGAATGGGACCCTCAAAAAGATGTCCACAATTTCACGGGATTG
AATAACAGTTACATCCTTGAAGACAAAATCGCGACAGTTGCAGGATATGAAGATCCAAGAGAAATCTACGATGAACTTGA
TTTAAGAGTTAGAATTCTTGAAGAAATGATTGCAAGAGGAATTTTTGGATACTACGAGGTTTTAGATATTATCTGGAGTT
TCTATGAAAAAGGATTGGAAGGACTGCCATTCCAGGTTTAA

Upstream 100 bases:

>100_bases
CAACTTTGCAAAAAGTTCTTTCCAGAAAGTTATGGTATTTAGAGTCGATCCAGGACTTGGAATTGCCGTAGAAATATCCT
CTGTAGCATAAGGTGGTAAT

Downstream 100 bases:

>100_bases
GGTGTTTCTTATGTTTTTTGATATACTCCCAAGGGTCGGACTAAAACCAAAAGATTACATTCTTAAATTTATACTTCCTG
CAAGCGTTATTTCACTTTTG

Product: type II secretion system protein E

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 545

Protein sequence:

>546_residues
MADDFKTAQMNNPHLRNYVEKFKKTYMKVPEFVPSLSRDFKEIKYPNIIYPIGDPIFIHLYGTPNLKTRYIAIEPKLNGS
EERKKYFDILDKILEYAPYSDIPENDEEFGKVVTKLFDMVAKVSSQKNEKKKGILSKITDSGKININKSERDKFLYLLKR
DLIGLGTLEPIKRDPYIEDIHVIGAKNCQLVHKIYDMLPSNIEWEDEGDISNYLKNMCERIGRPVSDATPIVDGSLPDGS
RINILYSGDVSLKGPSFTIRKFTDVPISITQIISWGTMSAQTAAYLWLCLEYGMSIFICGETASGKTTSLNAILPFIKPK
SKIFSCEDTSEVKPPNPVWQQLLTRERGPEESRVTLFDLLRAALRSRPNYIIVGEIRSVEGAVAFQAMQTGHPVISTFHA
ANVRKMIQRLTGDPICIPQTFMDNLNVCLFQLAVYARGKFLRRVVSVEEIEGYYKEVDGVITRGVFEWDPQKDVHNFTGL
NNSYILEDKIATVAGYEDPREIYDELDLRVRILEEMIARGIFGYYEVLDIIWSFYEKGLEGLPFQV

Sequences:

>Translated_546_residues
MADDFKTAQMNNPHLRNYVEKFKKTYMKVPEFVPSLSRDFKEIKYPNIIYPIGDPIFIHLYGTPNLKTRYIAIEPKLNGS
EERKKYFDILDKILEYAPYSDIPENDEEFGKVVTKLFDMVAKVSSQKNEKKKGILSKITDSGKININKSERDKFLYLLKR
DLIGLGTLEPIKRDPYIEDIHVIGAKNCQLVHKIYDMLPSNIEWEDEGDISNYLKNMCERIGRPVSDATPIVDGSLPDGS
RINILYSGDVSLKGPSFTIRKFTDVPISITQIISWGTMSAQTAAYLWLCLEYGMSIFICGETASGKTTSLNAILPFIKPK
SKIFSCEDTSEVKPPNPVWQQLLTRERGPEESRVTLFDLLRAALRSRPNYIIVGEIRSVEGAVAFQAMQTGHPVISTFHA
ANVRKMIQRLTGDPICIPQTFMDNLNVCLFQLAVYARGKFLRRVVSVEEIEGYYKEVDGVITRGVFEWDPQKDVHNFTGL
NNSYILEDKIATVAGYEDPREIYDELDLRVRILEEMIARGIFGYYEVLDIIWSFYEKGLEGLPFQV
>Mature_545_residues
ADDFKTAQMNNPHLRNYVEKFKKTYMKVPEFVPSLSRDFKEIKYPNIIYPIGDPIFIHLYGTPNLKTRYIAIEPKLNGSE
ERKKYFDILDKILEYAPYSDIPENDEEFGKVVTKLFDMVAKVSSQKNEKKKGILSKITDSGKININKSERDKFLYLLKRD
LIGLGTLEPIKRDPYIEDIHVIGAKNCQLVHKIYDMLPSNIEWEDEGDISNYLKNMCERIGRPVSDATPIVDGSLPDGSR
INILYSGDVSLKGPSFTIRKFTDVPISITQIISWGTMSAQTAAYLWLCLEYGMSIFICGETASGKTTSLNAILPFIKPKS
KIFSCEDTSEVKPPNPVWQQLLTRERGPEESRVTLFDLLRAALRSRPNYIIVGEIRSVEGAVAFQAMQTGHPVISTFHAA
NVRKMIQRLTGDPICIPQTFMDNLNVCLFQLAVYARGKFLRRVVSVEEIEGYYKEVDGVITRGVFEWDPQKDVHNFTGLN
NSYILEDKIATVAGYEDPREIYDELDLRVRILEEMIARGIFGYYEVLDIIWSFYEKGLEGLPFQV

Specific function: Involved In A General Secretion Pathway (Gsp) For The Export Of Proteins (By Similarity). [C]

COG id: COG0630

COG function: function code NU; Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 62414; Mature: 62282

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADDFKTAQMNNPHLRNYVEKFKKTYMKVPEFVPSLSRDFKEIKYPNIIYPIGDPIFIHL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEEE
YGTPNLKTRYIAIEPKLNGSEERKKYFDILDKILEYAPYSDIPENDEEFGKVVTKLFDMV
ECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
AKVSSQKNEKKKGILSKITDSGKININKSERDKFLYLLKRDLIGLGTLEPIKRDPYIEDI
HHHHHHCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
HVIGAKNCQLVHKIYDMLPSNIEWEDEGDISNYLKNMCERIGRPVSDATPIVDGSLPDGS
EEECCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
RINILYSGDVSLKGPSFTIRKFTDVPISITQIISWGTMSAQTAAYLWLCLEYGMSIFICG
EEEEEEECCEEECCCCEEEEEECCCCEEHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEC
ETASGKTTSLNAILPFIKPKSKIFSCEDTSEVKPPNPVWQQLLTRERGPEESRVTLFDLL
CCCCCCCEEHHHHCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHH
RAALRSRPNYIIVGEIRSVEGAVAFQAMQTGHPVISTFHAANVRKMIQRLTGDPICIPQT
HHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEECCHH
FMDNLNVCLFQLAVYARGKFLRRVVSVEEIEGYYKEVDGVITRGVFEWDPQKDVHNFTGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCHHHHHHCCC
NNSYILEDKIATVAGYEDPREIYDELDLRVRILEEMIARGIFGYYEVLDIIWSFYEKGLE
CCCEEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GLPFQV
CCCCCC
>Mature Secondary Structure 
ADDFKTAQMNNPHLRNYVEKFKKTYMKVPEFVPSLSRDFKEIKYPNIIYPIGDPIFIHL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEEE
YGTPNLKTRYIAIEPKLNGSEERKKYFDILDKILEYAPYSDIPENDEEFGKVVTKLFDMV
ECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
AKVSSQKNEKKKGILSKITDSGKININKSERDKFLYLLKRDLIGLGTLEPIKRDPYIEDI
HHHHHHCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
HVIGAKNCQLVHKIYDMLPSNIEWEDEGDISNYLKNMCERIGRPVSDATPIVDGSLPDGS
EEECCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
RINILYSGDVSLKGPSFTIRKFTDVPISITQIISWGTMSAQTAAYLWLCLEYGMSIFICG
EEEEEEECCEEECCCCEEEEEECCCCEEHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEC
ETASGKTTSLNAILPFIKPKSKIFSCEDTSEVKPPNPVWQQLLTRERGPEESRVTLFDLL
CCCCCCCEEHHHHCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHH
RAALRSRPNYIIVGEIRSVEGAVAFQAMQTGHPVISTFHAANVRKMIQRLTGDPICIPQT
HHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEECCHH
FMDNLNVCLFQLAVYARGKFLRRVVSVEEIEGYYKEVDGVITRGVFEWDPQKDVHNFTGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCHHHHHHCCC
NNSYILEDKIATVAGYEDPREIYDELDLRVRILEEMIARGIFGYYEVLDIIWSFYEKGLE
CCCEEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GLPFQV
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]