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The map label for this gene is cbiE [H]

Identifier: 45358790

GI number: 45358790

Start: 1216502

End: 1217242

Strand: Direct

Name: cbiE [H]

Synonym: MMP1227

Alternate gene names: 45358790

Gene position: 1216502-1217242 (Clockwise)

Preceding gene: 45358788

Following gene: 45358791

Centisome position: 73.23

GC content: 26.45

Gene sequence:

>741_bases
ATGGTATTCCTAAAAAATTTTTTCGAAAGGTTAATAGTTTTTAAATCTTATATTAAATATCATTTTAATATAGTTTCGCT
AAAAACTTGTTCAAAAAATTATAAATGGGATACCGTGATTTATATCGTTGGAATTGGGCCTGGAAGCAGGGATTATGTTA
CAGAAAAGGCATTTGATACCGTTGAAACTTCAGATTTTGTTTTGGGAAGTAAAAGGTCCCTTGAAATCTTTGAAATTAAC
GGAAAAAGAATGGAACTTACGCTAAATCTTAAAAACGAACTTTATGACTTTTTAAAGAATTATAAAAATTCAAATTCTAA
AGAAAAGGTTTCGATATTGTCAACTGGCGATCCCTGTTTCAGTGGCCTTTTAAAAACCATTTTTTCATTTGATTTTATTG
ATCAAAACGATTTTGAAGTAATTCCTGGAATTTCGTCAATTCAAATGGCAGCTGCAAAAGCTAAAATCTCTTGGGAAGAT
TATAACATTTTAACAATACATGGAAAAGAAGAAAATTTAAAAAAGCTGTTAGATTTTGTAAAAAATGATGAAAAAGTAAT
ATTTCTACCAAATAATTTAAAAAATGACATTAAATTCTTAATTGAAAATGGAATTTCGGACGAAAAAGAAATAACTGTTC
TTGAAAATCTTTCATATTCAAACGAAAGAATAATTACAAATAAAATATCAAATTTAGTGAAAAATGATTATTCGTACCTT
TTAGTCTGCATTATAAACTAA

Upstream 100 bases:

>100_bases
TTCTTCTAAAACGAGAACTTTTTTATTCTTAATATTCTCTCCCGTGATAAATCCACAAGGTCCGCCGCCAACAATTACAA
CATCGTACTTTTCAAAATCC

Downstream 100 bases:

>100_bases
AGAGGAGATACTTTTGAAAAAAGTGGCCGGTTTACTTTCAGTCTTTGGATTATTACTATTAACCCTATTTTCAGGATGTA
TTGGAAACGACTACAGCTCT

Product: cobalt-precorrin-6Y C(5)-methyltransferase

Products: S-adenosyl-L-homocysteine; Precorrin 8X; CO2

Alternate protein names: Cobalt-precorrin-6 methyltransferase; Cobalt-precorrin-6Y methylase [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MVFLKNFFERLIVFKSYIKYHFNIVSLKTCSKNYKWDTVIYIVGIGPGSRDYVTEKAFDTVETSDFVLGSKRSLEIFEIN
GKRMELTLNLKNELYDFLKNYKNSNSKEKVSILSTGDPCFSGLLKTIFSFDFIDQNDFEVIPGISSIQMAAAKAKISWED
YNILTIHGKEENLKKLLDFVKNDEKVIFLPNNLKNDIKFLIENGISDEKEITVLENLSYSNERIITNKISNLVKNDYSYL
LVCIIN

Sequences:

>Translated_246_residues
MVFLKNFFERLIVFKSYIKYHFNIVSLKTCSKNYKWDTVIYIVGIGPGSRDYVTEKAFDTVETSDFVLGSKRSLEIFEIN
GKRMELTLNLKNELYDFLKNYKNSNSKEKVSILSTGDPCFSGLLKTIFSFDFIDQNDFEVIPGISSIQMAAAKAKISWED
YNILTIHGKEENLKKLLDFVKNDEKVIFLPNNLKNDIKFLIENGISDEKEITVLENLSYSNERIITNKISNLVKNDYSYL
LVCIIN
>Mature_246_residues
MVFLKNFFERLIVFKSYIKYHFNIVSLKTCSKNYKWDTVIYIVGIGPGSRDYVTEKAFDTVETSDFVLGSKRSLEIFEIN
GKRMELTLNLKNELYDFLKNYKNSNSKEKVSILSTGDPCFSGLLKTIFSFDFIDQNDFEVIPGISSIQMAAAKAKISWED
YNILTIHGKEENLKKLLDFVKNDEKVIFLPNNLKNDIKFLIENGISDEKEITVLENLSYSNERIITNKISNLVKNDYSYL
LVCIIN

Specific function: Probably catalyzes the methylation of C-5 in cobalt- precorrin-6Y to form cobalt-precorrin-7W-a [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR012818 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: 2.1.1.132

Molecular weight: Translated: 28464; Mature: 28464

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFLKNFFERLIVFKSYIKYHFNIVSLKTCSKNYKWDTVIYIVGIGPGSRDYVTEKAFDT
CCHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCEEEEEEEEEECCCCCCHHHHHHHCC
VETSDFVLGSKRSLEIFEINGKRMELTLNLKNELYDFLKNYKNSNSKEKVSILSTGDPCF
CCCCCEEECCCCCEEEEEECCCEEEEEEECHHHHHHHHHHHCCCCCCCEEEEEECCCHHH
SGLLKTIFSFDFIDQNDFEVIPGISSIQMAAAKAKISWEDYNILTIHGKEENLKKLLDFV
HHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHEEEEECCEEEEEEECCHHHHHHHHHHH
KNDEKVIFLPNNLKNDIKFLIENGISDEKEITVLENLSYSNERIITNKISNLVKNDYSYL
CCCCEEEEECCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCEEHHHHHHHHHHCCCEEE
LVCIIN
EEEEEC
>Mature Secondary Structure
MVFLKNFFERLIVFKSYIKYHFNIVSLKTCSKNYKWDTVIYIVGIGPGSRDYVTEKAFDT
CCHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCEEEEEEEEEECCCCCCHHHHHHHCC
VETSDFVLGSKRSLEIFEINGKRMELTLNLKNELYDFLKNYKNSNSKEKVSILSTGDPCF
CCCCCEEECCCCCEEEEEECCCEEEEEEECHHHHHHHHHHHCCCCCCCEEEEEECCCHHH
SGLLKTIFSFDFIDQNDFEVIPGISSIQMAAAKAKISWEDYNILTIHGKEENLKKLLDFV
HHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHEEEEECCEEEEEEECCHHHHHHHHHHH
KNDEKVIFLPNNLKNDIKFLIENGISDEKEITVLENLSYSNERIITNKISNLVKNDYSYL
CCCCEEEEECCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCEEHHHHHHHHHHCCCEEE
LVCIIN
EEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-adenosyl-L-methionine; Precorrin 6Y

Specific reaction: 2 S-adenosyl-L-methionine + precorrin-6Y = 2 S-adenosyl-L-homocysteine + precorrin-8X + CO2

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]