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The map label for this gene is btuC [C]

Identifier: 45358745

GI number: 45358745

Start: 1165563

End: 1166609

Strand: Direct

Name: btuC [C]

Synonym: MMP1182

Alternate gene names: 45358745

Gene position: 1165563-1166609 (Clockwise)

Preceding gene: 45358744

Following gene: 45358746

Centisome position: 70.17

GC content: 37.73

Gene sequence:

>1047_bases
GTGGAAAATTCTGTTAATACTTACAAAAAATATACTTTAAAAAAACTAATATTCGGATTTGTACTGATTATAGCCCTAAT
AATAATCTCTATTTATTCACTATGCACCGGAGATTTCCAGTTATCAATCAGCCAGATTATAAATTCATTGTTAGGTTCTG
GAGACGCTTCTTCAAACCTTGTTATATGGAATATCAGACTTCCGAGAATCTTTGCGGCAATACTATGTGGAATTGGATTA
TCTGTTTCAGGTGCAGTGATGCAGTGTGTTTTAAGAAACCCGCTCGCATCCCCATATACCATGGGAATTTCTCATGGGGC
CATGTTTGGAGCATGTGTTGCAATAATTACGCTTGGAATCGGCGGTGCTGAAAGTACCGGACATATTGCAATAAACAATC
CTTATTCCATAACGATATTTGCATTTTTAGGTTCACTACTTGGCGTTTGTGCAGTGTTGATCCTAGCCAAATTAAAGGGA
TTAAGTCCTGAAGCAATGGTTCTTGCAGGGGTTGCAATATCTTCGCTATTTACTGCTGCAACCACACTCATACAGTATTT
TGCAGACGATATGCAATTAGCTGCAATGGTTTACTGGTCATTTGGTGACCTTGGAAGACCGCTATGGCCAGAAGTAAAAA
TTATGGCCTTTGTAGCATTTGTTTCACTTATTTACTTTATACATAAACGATGGGACTATAACGCTCTTGAAAGCGGTGAA
GAAACTGCAAAATCTCTTGGCGTTAACACGGATAAAATAAGACTGTCAGGAATGCTTGTTGCATCCCTTGTAACATCTGT
TTGTGTTGCATTCTTAGGAATTATTGGATTTGTAGGCTTAATCTGCCCACATATAATAAGGATAACTGTTGGGGGAGATT
ACAGGTACTTAATTCCACTGTGCAGTATTTTTGGTGCAGTTTTGGTACTATTAGCAGATACAATTGCAAGAACAATAATT
TCCCCAATAATTCTGCCTGTAGGAATACTTACCTCATTTTTAGGGGCGCCAATGTTCCTTTATTTACTAACGAAGATGTA
TAAATGA

Upstream 100 bases:

>100_bases
ATTATTTTTTTAAAAAATTTATTTTTTCATAATATTAAATACTTATTTATAGGTTAAAATAATACTTATTTTATAAGTGT
ATTACCAAAACAGGGATAAC

Downstream 100 bases:

>100_bases
TAGGTTCGGGTGAAAATATGATAGTTTCAGTAGAGGGAGTTGAATTCAAATATAAAAGTACTGAAATATTAAAAGACGTT
AAATTTGAAGTAGAAAAAGG

Product: transport system permease

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MENSVNTYKKYTLKKLIFGFVLIIALIIISIYSLCTGDFQLSISQIINSLLGSGDASSNLVIWNIRLPRIFAAILCGIGL
SVSGAVMQCVLRNPLASPYTMGISHGAMFGACVAIITLGIGGAESTGHIAINNPYSITIFAFLGSLLGVCAVLILAKLKG
LSPEAMVLAGVAISSLFTAATTLIQYFADDMQLAAMVYWSFGDLGRPLWPEVKIMAFVAFVSLIYFIHKRWDYNALESGE
ETAKSLGVNTDKIRLSGMLVASLVTSVCVAFLGIIGFVGLICPHIIRITVGGDYRYLIPLCSIFGAVLVLLADTIARTII
SPIILPVGILTSFLGAPMFLYLLTKMYK

Sequences:

>Translated_348_residues
MENSVNTYKKYTLKKLIFGFVLIIALIIISIYSLCTGDFQLSISQIINSLLGSGDASSNLVIWNIRLPRIFAAILCGIGL
SVSGAVMQCVLRNPLASPYTMGISHGAMFGACVAIITLGIGGAESTGHIAINNPYSITIFAFLGSLLGVCAVLILAKLKG
LSPEAMVLAGVAISSLFTAATTLIQYFADDMQLAAMVYWSFGDLGRPLWPEVKIMAFVAFVSLIYFIHKRWDYNALESGE
ETAKSLGVNTDKIRLSGMLVASLVTSVCVAFLGIIGFVGLICPHIIRITVGGDYRYLIPLCSIFGAVLVLLADTIARTII
SPIILPVGILTSFLGAPMFLYLLTKMYK
>Mature_348_residues
MENSVNTYKKYTLKKLIFGFVLIIALIIISIYSLCTGDFQLSISQIINSLLGSGDASSNLVIWNIRLPRIFAAILCGIGL
SVSGAVMQCVLRNPLASPYTMGISHGAMFGACVAIITLGIGGAESTGHIAINNPYSITIFAFLGSLLGVCAVLILAKLKG
LSPEAMVLAGVAISSLFTAATTLIQYFADDMQLAAMVYWSFGDLGRPLWPEVKIMAFVAFVSLIYFIHKRWDYNALESGE
ETAKSLGVNTDKIRLSGMLVASLVTSVCVAFLGIIGFVGLICPHIIRITVGGDYRYLIPLCSIFGAVLVLLADTIARTII
SPIILPVGILTSFLGAPMFLYLLTKMYK

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788004, Length=289, Percent_Identity=35.6401384083045, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1790740, Length=287, Percent_Identity=32.7526132404181, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1790741, Length=329, Percent_Identity=30.0911854103343, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1786347, Length=301, Percent_Identity=30.8970099667774, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1786804, Length=335, Percent_Identity=30.4477611940298, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1786805, Length=317, Percent_Identity=28.7066246056782, Blast_Score=105, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37345; Mature: 37345

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENSVNTYKKYTLKKLIFGFVLIIALIIISIYSLCTGDFQLSISQIINSLLGSGDASSNL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCE
VIWNIRLPRIFAAILCGIGLSVSGAVMQCVLRNPLASPYTMGISHGAMFGACVAIITLGI
EEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHCC
GGAESTGHIAINNPYSITIFAFLGSLLGVCAVLILAKLKGLSPEAMVLAGVAISSLFTAA
CCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
TTLIQYFADDMQLAAMVYWSFGDLGRPLWPEVKIMAFVAFVSLIYFIHKRWDYNALESGE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHH
ETAKSLGVNTDKIRLSGMLVASLVTSVCVAFLGIIGFVGLICPHIIRITVGGDYRYLIPL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHH
CSIFGAVLVLLADTIARTIISPIILPVGILTSFLGAPMFLYLLTKMYK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MENSVNTYKKYTLKKLIFGFVLIIALIIISIYSLCTGDFQLSISQIINSLLGSGDASSNL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCE
VIWNIRLPRIFAAILCGIGLSVSGAVMQCVLRNPLASPYTMGISHGAMFGACVAIITLGI
EEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHCC
GGAESTGHIAINNPYSITIFAFLGSLLGVCAVLILAKLKGLSPEAMVLAGVAISSLFTAA
CCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
TTLIQYFADDMQLAAMVYWSFGDLGRPLWPEVKIMAFVAFVSLIYFIHKRWDYNALESGE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHH
ETAKSLGVNTDKIRLSGMLVASLVTSVCVAFLGIIGFVGLICPHIIRITVGGDYRYLIPL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHH
CSIFGAVLVLLADTIARTIISPIILPVGILTSFLGAPMFLYLLTKMYK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]