Click here to switch to the map view.

The map label for this gene is thiL [H]

Identifier: 45358687

GI number: 45358687

Start: 1114567

End: 1115514

Strand: Direct

Name: thiL [H]

Synonym: MMP1124

Alternate gene names: 45358687

Gene position: 1114567-1115514 (Clockwise)

Preceding gene: 45358683

Following gene: 45358688

Centisome position: 67.1

GC content: 31.33

Gene sequence:

>948_bases
ATGAATGAACTTGATATCATTAAAATTATTTCAAAGAATCTTTCTTATTCAAATGGAGTTGAAAAAGGAATTGGGGATGA
CTGTGCTGTTTTTAAATTTGAAAATCAGCATTTAGTTGTAACTACCGACATGATGTTTAAATCAACACATTTTCCAAGTA
TTTTAACACCGTTTCAAATAGGAATGAGGGTTGTTACTGCAAATGTATCCGATATTGCCGCAATGTGTGCAAAACCTCTT
GGAATGGTAATTTCGATGGGTTTTGATAATCCAAAAAAAACATTTATCGATGAAATGTCAAAAGGGATAAATTTTATTTC
AAAAGAATATGGATGTCCAATTGCAGGCGGGGATACAAATAAAGCGCCGGAATTAACACTTTCAGGAACTGCATTTGGAA
TTACCGATAATCCAATATATCGCGGTGGAATTATTGGTGAAGATATCTGCATTACTGGGGATGTTGGAAAAGTTAATTGT
GCTTTAAAACTTCTTGAAATGAAAGATAAAGGAATTTTGGGAAATATAGAGTTTGAAAAAACAATGTCTGAATTTCCTAG
GATCATGAAAAAACTTGCAGAACCTAAAGCAAGGGTTAAAGAAGGGCTTTTATTAAATAAAATAATCACTTCGTGCTGTG
ACATATCTGACGGTCTTTCAAAAGATTTAAATTATACTGGAAACTTTGAAATAAATTCAAAAAATTTATTAAACTCCGTT
TCAAGAGAGGTTATTGAATTTTGCGAAAAATTTGATATGGATTTATTAAAAACGGTTTTAAACAGCGGTGAAGAATTTGA
ACTACTTTTTACAACTCCTGATTTTAAAAAAGCCGAAGAAAAATTAAAAGATATAAATTCAGTAACAAAAATTGGAAAAG
TCGTGGAATCTGGAAAAACGGTTGATGGAATATCCGTGGAATTAGAAGGATATGTTCACAAATGGTAG

Upstream 100 bases:

>100_bases
TAATTTTTTGAATGCAACTTCAATACCGTTAATTTTTAGCTAAATATTTTAAAGAGATTTTCCATAAAAACTATCAAACT
TTTAAAAAACAGGAACAAAA

Downstream 100 bases:

>100_bases
GTTGCTAAATAGGATATAGCATGACATGCAACATGATTAAACATGAATAAAAAATTTAATGAACATTTTTTAATAATCTT
AAAATACTTTACTTATTCAT

Product: thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MNELDIIKIISKNLSYSNGVEKGIGDDCAVFKFENQHLVVTTDMMFKSTHFPSILTPFQIGMRVVTANVSDIAAMCAKPL
GMVISMGFDNPKKTFIDEMSKGINFISKEYGCPIAGGDTNKAPELTLSGTAFGITDNPIYRGGIIGEDICITGDVGKVNC
ALKLLEMKDKGILGNIEFEKTMSEFPRIMKKLAEPKARVKEGLLLNKIITSCCDISDGLSKDLNYTGNFEINSKNLLNSV
SREVIEFCEKFDMDLLKTVLNSGEEFELLFTTPDFKKAEEKLKDINSVTKIGKVVESGKTVDGISVELEGYVHKW

Sequences:

>Translated_315_residues
MNELDIIKIISKNLSYSNGVEKGIGDDCAVFKFENQHLVVTTDMMFKSTHFPSILTPFQIGMRVVTANVSDIAAMCAKPL
GMVISMGFDNPKKTFIDEMSKGINFISKEYGCPIAGGDTNKAPELTLSGTAFGITDNPIYRGGIIGEDICITGDVGKVNC
ALKLLEMKDKGILGNIEFEKTMSEFPRIMKKLAEPKARVKEGLLLNKIITSCCDISDGLSKDLNYTGNFEINSKNLLNSV
SREVIEFCEKFDMDLLKTVLNSGEEFELLFTTPDFKKAEEKLKDINSVTKIGKVVESGKTVDGISVELEGYVHKW
>Mature_315_residues
MNELDIIKIISKNLSYSNGVEKGIGDDCAVFKFENQHLVVTTDMMFKSTHFPSILTPFQIGMRVVTANVSDIAAMCAKPL
GMVISMGFDNPKKTFIDEMSKGINFISKEYGCPIAGGDTNKAPELTLSGTAFGITDNPIYRGGIIGEDICITGDVGKVNC
ALKLLEMKDKGILGNIEFEKTMSEFPRIMKKLAEPKARVKEGLLLNKIITSCCDISDGLSKDLNYTGNFEINSKNLLNSV
SREVIEFCEKFDMDLLKTVLNSGEEFELLFTTPDFKKAEEKLKDINSVTKIGKVVESGKTVDGISVELEGYVHKW

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=266, Percent_Identity=25.187969924812, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 34732; Mature: 34732

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNELDIIKIISKNLSYSNGVEKGIGDDCAVFKFENQHLVVTTDMMFKSTHFPSILTPFQI
CCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCEEEEEEHHHHHCCCCCCHHCHHHH
GMRVVTANVSDIAAMCAKPLGMVISMGFDNPKKTFIDEMSKGINFISKEYGCPIAGGDTN
CCEEEECCHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
KAPELTLSGTAFGITDNPIYRGGIIGEDICITGDVGKVNCALKLLEMKDKGILGNIEFEK
CCCEEEECCEEECCCCCCEEECCCCCCCEEEECCCCCHHHHHHEEECCCCCCEECCHHHH
TMSEFPRIMKKLAEPKARVKEGLLLNKIITSCCDISDGLSKDLNYTGNFEINSKNLLNSV
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCEEECHHHHHHHH
SREVIEFCEKFDMDLLKTVLNSGEEFELLFTTPDFKKAEEKLKDINSVTKIGKVVESGKT
HHHHHHHHHHHCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCC
VDGISVELEGYVHKW
CCCEEEEEECEEECC
>Mature Secondary Structure
MNELDIIKIISKNLSYSNGVEKGIGDDCAVFKFENQHLVVTTDMMFKSTHFPSILTPFQI
CCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCEEEEEEHHHHHCCCCCCHHCHHHH
GMRVVTANVSDIAAMCAKPLGMVISMGFDNPKKTFIDEMSKGINFISKEYGCPIAGGDTN
CCEEEECCHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
KAPELTLSGTAFGITDNPIYRGGIIGEDICITGDVGKVNCALKLLEMKDKGILGNIEFEK
CCCEEEECCEEECCCCCCEEECCCCCCCEEEECCCCCHHHHHHEEECCCCCCEECCHHHH
TMSEFPRIMKKLAEPKARVKEGLLLNKIITSCCDISDGLSKDLNYTGNFEINSKNLLNSV
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCEEECHHHHHHHH
SREVIEFCEKFDMDLLKTVLNSGEEFELLFTTPDFKKAEEKLKDINSVTKIGKVVESGKT
HHHHHHHHHHHCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCC
VDGISVELEGYVHKW
CCCEEEEEECEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]