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The map label for this gene is yclK [H]

Identifier: 45358683

GI number: 45358683

Start: 1109187

End: 1111031

Strand: Direct

Name: yclK [H]

Synonym: MMP1120

Alternate gene names: 45358683

Gene position: 1109187-1111031 (Clockwise)

Preceding gene: 45358682

Following gene: 45358687

Centisome position: 66.77

GC content: 33.55

Gene sequence:

>1845_bases
ATGAGAAGATCGAGAATTGGAATGATTGGAACTAAACTGCTGATTTTTTCAATAATTATTGTTTTAATTCCAATCGTTAT
GATGAGTTATGTATCTACAGATACAATTTCAGATCTGATGACTTCAAATCAGGAATCTGAACTAGATATAAATTTAGGAA
TATTAAATGAACGAATGGACAGCGTTCTTGTTGAATTTGACACGATGACTGCATATACTGCAGACCTTCCAGTTGTTGTT
AATGCTGTTAAAAATAATGATAAAGATACGCTTCAAGATTTTGCAAACGGCCTTGAAGACCAGTCTTGGATCGATTTAGC
AGTTTTTACTGATGCGGATGGAAACGTAATCTGTGCAAGCTATGGAGACGATAATGCAGAAATAAGCAGTTACGTTAAAA
AATTATTAGAAAAAAATACGATATATGCATACGATATCCTCCCAAACGAAGAAGCTTCAAAATATAGCGAGTATGAGCTA
GATGGGAACGATGCACTTACAATTTTTACGGTTGCACCAATCTATGATGGAAATTCCCTCATTGGTACGGTAACTTACGT
AGATATCATGAATAAGGATGATTACTGGGTTGACCGAGTTAAAGAAGTTACCGGTGATGAAGCTTCGATATATCTTAACA
ACGTAAGAATATCTACAACCTGCATAAAAGATGGAGTAGATTTTGTTGGTGAACTTGCAGATGAAGACATATATGAAACG
GTTTCAAAAAAACAGGACGTTAGGAGTACCGTTACCATAAATGGAGTGCCATACCTTGCTAAATATTCCCCAATATACAA
TATTGACGGCGAAGTAATAGGAATGACCTGTGTTGGAACCCCAAAATCGCCATTTACGGCATTATTAAATTCAGTAATCC
AGAAAATATTCTTTATCGCATTTTCAAGCCTGATTATTGCAGTTTTCGTTGCAGTTATCTTAAATAAAAAAATAGTTGAC
TCGATAAAAAAACTTAAAAACTCTGCTGAATCTTTTGGACGTGGAAATTACGACGAAAGAGCATCAATTGATACAGGCGA
TGAATTAGAAGAACTTGCAGAATCGTTTAATAAAATGGCTGATGAAATAGGGAAATCCGATAAAAAACTTAAAAGTGATG
CACATACGCTTAAAACTTCATTTGACGAATTAAAAGAAGTTGATAATTTAAAATCAGAAATACTGTCCATAGTATCACAC
GAACTTAGAACGCCACTTACTGCAATCTTAGGCTATGTTGAATTATTAAAAGATGAAACTGCAGGAAAATTAAGCGAAAA
ACAGAAAGAATTCATATCTGTAATATCTGAAAACTCAGACAGGTTAAAAAGAATTACAGACAATATGTCAGACCTTGTAA
CTGTTGATAATAAGATTTTGGACATCAAACGAGACAGAATAAACCTTAAAAAAGAAGTAAATGATATTTTAAGGTCTTTT
GATTATTTCGCAGAAAGTAAAAATATAGTTTTACTCGAAGATGTGGATAATCTGGATATTAAAGGAGATAAGTCTAAAAT
TCATCAGGTTCTTAGTAATTTAATCGAAAATGCAATAAAATTCAGCAAAAAACAGACCAAAGTTACAGTGATGGGTTTTG
AAGATAAAGGAAATATCCACCTTGAAATTACTGATCAGGGACCAGGAATTCCAAAAGAGCACCTTGGAAAAATATTTGAT
AAATTCTACCAGATAGATTCTTCTTCAAAACGAGAAGTTGGAGGATCCGGCCTTGGACTTGCAGTTTGTAAAAAAATCGT
TGAATCACACGGCGGATCGATATGGGTTGAAAGCAAAATTGGAAAAGGTACAACAGTTCATGTAATGTTCCCATTAATAA
AATAA

Upstream 100 bases:

>100_bases
AACAAATAATTATTTAATAATATTCCTAAATATTTAACTAAAATAATTAAATGAGAATATTTAAAAAAATTTACTCAAAC
TGACTTATTTAGTGGTGCCC

Downstream 100 bases:

>100_bases
AAAACTTAAAAAAATTACTTTTTAAAAAAGTTAAATTTTAAAATTAATTAAATGAAATATTTTCTTTTACTTCTTTTAAA
ACAGAATCTACAAAATCATC

Product: ATPase-like ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 614; Mature: 614

Protein sequence:

>614_residues
MRRSRIGMIGTKLLIFSIIIVLIPIVMMSYVSTDTISDLMTSNQESELDINLGILNERMDSVLVEFDTMTAYTADLPVVV
NAVKNNDKDTLQDFANGLEDQSWIDLAVFTDADGNVICASYGDDNAEISSYVKKLLEKNTIYAYDILPNEEASKYSEYEL
DGNDALTIFTVAPIYDGNSLIGTVTYVDIMNKDDYWVDRVKEVTGDEASIYLNNVRISTTCIKDGVDFVGELADEDIYET
VSKKQDVRSTVTINGVPYLAKYSPIYNIDGEVIGMTCVGTPKSPFTALLNSVIQKIFFIAFSSLIIAVFVAVILNKKIVD
SIKKLKNSAESFGRGNYDERASIDTGDELEELAESFNKMADEIGKSDKKLKSDAHTLKTSFDELKEVDNLKSEILSIVSH
ELRTPLTAILGYVELLKDETAGKLSEKQKEFISVISENSDRLKRITDNMSDLVTVDNKILDIKRDRINLKKEVNDILRSF
DYFAESKNIVLLEDVDNLDIKGDKSKIHQVLSNLIENAIKFSKKQTKVTVMGFEDKGNIHLEITDQGPGIPKEHLGKIFD
KFYQIDSSSKREVGGSGLGLAVCKKIVESHGGSIWVESKIGKGTTVHVMFPLIK

Sequences:

>Translated_614_residues
MRRSRIGMIGTKLLIFSIIIVLIPIVMMSYVSTDTISDLMTSNQESELDINLGILNERMDSVLVEFDTMTAYTADLPVVV
NAVKNNDKDTLQDFANGLEDQSWIDLAVFTDADGNVICASYGDDNAEISSYVKKLLEKNTIYAYDILPNEEASKYSEYEL
DGNDALTIFTVAPIYDGNSLIGTVTYVDIMNKDDYWVDRVKEVTGDEASIYLNNVRISTTCIKDGVDFVGELADEDIYET
VSKKQDVRSTVTINGVPYLAKYSPIYNIDGEVIGMTCVGTPKSPFTALLNSVIQKIFFIAFSSLIIAVFVAVILNKKIVD
SIKKLKNSAESFGRGNYDERASIDTGDELEELAESFNKMADEIGKSDKKLKSDAHTLKTSFDELKEVDNLKSEILSIVSH
ELRTPLTAILGYVELLKDETAGKLSEKQKEFISVISENSDRLKRITDNMSDLVTVDNKILDIKRDRINLKKEVNDILRSF
DYFAESKNIVLLEDVDNLDIKGDKSKIHQVLSNLIENAIKFSKKQTKVTVMGFEDKGNIHLEITDQGPGIPKEHLGKIFD
KFYQIDSSSKREVGGSGLGLAVCKKIVESHGGSIWVESKIGKGTTVHVMFPLIK
>Mature_614_residues
MRRSRIGMIGTKLLIFSIIIVLIPIVMMSYVSTDTISDLMTSNQESELDINLGILNERMDSVLVEFDTMTAYTADLPVVV
NAVKNNDKDTLQDFANGLEDQSWIDLAVFTDADGNVICASYGDDNAEISSYVKKLLEKNTIYAYDILPNEEASKYSEYEL
DGNDALTIFTVAPIYDGNSLIGTVTYVDIMNKDDYWVDRVKEVTGDEASIYLNNVRISTTCIKDGVDFVGELADEDIYET
VSKKQDVRSTVTINGVPYLAKYSPIYNIDGEVIGMTCVGTPKSPFTALLNSVIQKIFFIAFSSLIIAVFVAVILNKKIVD
SIKKLKNSAESFGRGNYDERASIDTGDELEELAESFNKMADEIGKSDKKLKSDAHTLKTSFDELKEVDNLKSEILSIVSH
ELRTPLTAILGYVELLKDETAGKLSEKQKEFISVISENSDRLKRITDNMSDLVTVDNKILDIKRDRINLKKEVNDILRSF
DYFAESKNIVLLEDVDNLDIKGDKSKIHQVLSNLIENAIKFSKKQTKVTVMGFEDKGNIHLEITDQGPGIPKEHLGKIFD
KFYQIDSSSKREVGGSGLGLAVCKKIVESHGGSIWVESKIGKGTTVHVMFPLIK

Specific function: Could be member of the two-component regulatory system yclK/yclJ. Potentially phosphorylates yclJ [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=230, Percent_Identity=26.5217391304348, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI1786783, Length=327, Percent_Identity=27.82874617737, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1788393, Length=298, Percent_Identity=24.1610738255034, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1789149, Length=342, Percent_Identity=25.7309941520468, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1786912, Length=240, Percent_Identity=29.5833333333333, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI145693157, Length=226, Percent_Identity=30.5309734513274, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788279, Length=309, Percent_Identity=30.7443365695793, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI48994928, Length=229, Percent_Identity=32.3144104803493, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788713, Length=229, Percent_Identity=31.0043668122271, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=29.7872340425532, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790346, Length=305, Percent_Identity=26.5573770491803, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787894, Length=330, Percent_Identity=24.2424242424242, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI87081816, Length=302, Percent_Identity=24.8344370860927, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788549, Length=252, Percent_Identity=26.5873015873016, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87082128, Length=232, Percent_Identity=23.2758620689655, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1790861, Length=376, Percent_Identity=22.8723404255319, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790551, Length=208, Percent_Identity=26.4423076923077, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1789808, Length=342, Percent_Identity=21.6374269005848, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 68395; Mature: 68395

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRSRIGMIGTKLLIFSIIIVLIPIVMMSYVSTDTISDLMTSNQESELDINLGILNERMD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHH
SVLVEFDTMTAYTADLPVVVNAVKNNDKDTLQDFANGLEDQSWIDLAVFTDADGNVICAS
HHHHHHHHHHEEECCCCHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEE
YGDDNAEISSYVKKLLEKNTIYAYDILPNEEASKYSEYELDGNDALTIFTVAPIYDGNSL
CCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEECCCCEEEEEEEEEEECCCCE
IGTVTYVDIMNKDDYWVDRVKEVTGDEASIYLNNVRISTTCIKDGVDFVGELADEDIYET
EEEEEEEEEECCCCHHHHHHHHHCCCCCEEEEECEEEEEHHHHHHHHHHHHHHHHHHHHH
VSKKQDVRSTVTINGVPYLAKYSPIYNIDGEVIGMTCVGTPKSPFTALLNSVIQKIFFIA
HHHHHHHCCEEEECCCCCCEECCCEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHH
FSSLIIAVFVAVILNKKIVDSIKKLKNSAESFGRGNYDERASIDTGDELEELAESFNKMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
DEIGKSDKKLKSDAHTLKTSFDELKEVDNLKSEILSIVSHELRTPLTAILGYVELLKDET
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
AGKLSEKQKEFISVISENSDRLKRITDNMSDLVTVDNKILDIKRDRINLKKEVNDILRSF
HHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHH
DYFAESKNIVLLEDVDNLDIKGDKSKIHQVLSNLIENAIKFSKKQTKVTVMGFEDKGNIH
HHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEE
LEITDQGPGIPKEHLGKIFDKFYQIDSSSKREVGGSGLGLAVCKKIVESHGGSIWVESKI
EEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECC
GKGTTVHVMFPLIK
CCCCEEEEEEECCC
>Mature Secondary Structure
MRRSRIGMIGTKLLIFSIIIVLIPIVMMSYVSTDTISDLMTSNQESELDINLGILNERMD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHH
SVLVEFDTMTAYTADLPVVVNAVKNNDKDTLQDFANGLEDQSWIDLAVFTDADGNVICAS
HHHHHHHHHHEEECCCCHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEE
YGDDNAEISSYVKKLLEKNTIYAYDILPNEEASKYSEYELDGNDALTIFTVAPIYDGNSL
CCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEECCCCEEEEEEEEEEECCCCE
IGTVTYVDIMNKDDYWVDRVKEVTGDEASIYLNNVRISTTCIKDGVDFVGELADEDIYET
EEEEEEEEEECCCCHHHHHHHHHCCCCCEEEEECEEEEEHHHHHHHHHHHHHHHHHHHHH
VSKKQDVRSTVTINGVPYLAKYSPIYNIDGEVIGMTCVGTPKSPFTALLNSVIQKIFFIA
HHHHHHHCCEEEECCCCCCEECCCEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHH
FSSLIIAVFVAVILNKKIVDSIKKLKNSAESFGRGNYDERASIDTGDELEELAESFNKMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
DEIGKSDKKLKSDAHTLKTSFDELKEVDNLKSEILSIVSHELRTPLTAILGYVELLKDET
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
AGKLSEKQKEFISVISENSDRLKRITDNMSDLVTVDNKILDIKRDRINLKKEVNDILRSF
HHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHH
DYFAESKNIVLLEDVDNLDIKGDKSKIHQVLSNLIENAIKFSKKQTKVTVMGFEDKGNIH
HHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEE
LEITDQGPGIPKEHLGKIFDKFYQIDSSSKREVGGSGLGLAVCKKIVESHGGSIWVESKI
EEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECC
GKGTTVHVMFPLIK
CCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]