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The map label for this gene is pyrI [H]

Identifier: 45358667

GI number: 45358667

Start: 1095867

End: 1096313

Strand: Direct

Name: pyrI [H]

Synonym: MMP1104

Alternate gene names: 45358667

Gene position: 1095867-1096313 (Clockwise)

Preceding gene: 45358666

Following gene: 45358668

Centisome position: 65.97

GC content: 32.89

Gene sequence:

>447_bases
ATGAAACGGGAACTCAAAGTAAAACCCATTGAAAACGGAACTGTTATCGACCATATCAGTGGATCAAAAGCACTGAAAGT
CTATAAAATCCTGAATATCGAAGAAAAACTCCCAATAACACTTGCACTAAACGTGCCGTCAAAAAAAGGCGTTACAAAAG
ATATTTTAAAAATTGAAGGGCTTGAACTCTCAAAAGACGATGTAAACAAAATTGCGTTAATTTCACCAGATGCAACGATA
AACATCATAAAAGAAGGAAAAGTCATAAAAAAATTTAAAGTAGACATTCCAAAAAGAATCGATGGAATAATCAAATGCAC
CAATCCAAACTGCATCACGAACAAGGAAAATATCGAAAGCAGATTCTCGATCGAACAGAAAAACACGTTAAAAATCAGGT
GCGAATACTGCGAAAAATTCATTAATTCAATTATAATCTCAAAATAA

Upstream 100 bases:

>100_bases
GATGCCTTTGAAATGCTCGAAGAAATTATAAAATATATTGAAAAACAGTAATGATTTAAAACAGTTTTTTAATAGGATAT
ATAAAAAATCTGGTGAAGTC

Downstream 100 bases:

>100_bases
ACCCTAGTTTTTTTATATTTTCAGTAACTATTATCATGAGAACTGTTGGTGATTTTTATGAAATTACACGAATATGAAGC
AAAGGAAATTTTTAAAGAAA

Product: aspartate carbamoyltransferase regulatory subunit

Products: phosphate; N-carbamoyl-L-aspartate

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MKRELKVKPIENGTVIDHISGSKALKVYKILNIEEKLPITLALNVPSKKGVTKDILKIEGLELSKDDVNKIALISPDATI
NIIKEGKVIKKFKVDIPKRIDGIIKCTNPNCITNKENIESRFSIEQKNTLKIRCEYCEKFINSIIISK

Sequences:

>Translated_148_residues
MKRELKVKPIENGTVIDHISGSKALKVYKILNIEEKLPITLALNVPSKKGVTKDILKIEGLELSKDDVNKIALISPDATI
NIIKEGKVIKKFKVDIPKRIDGIIKCTNPNCITNKENIESRFSIEQKNTLKIRCEYCEKFINSIIISK
>Mature_148_residues
MKRELKVKPIENGTVIDHISGSKALKVYKILNIEEKLPITLALNVPSKKGVTKDILKIEGLELSKDDVNKIALISPDATI
NIIKEGKVIKKFKVDIPKRIDGIIKCTNPNCITNKENIESRFSIEQKNTLKIRCEYCEKFINSIIISK

Specific function: Involved in allosteric regulation of aspartate carbamoyltransferase [H]

COG id: COG1781

COG function: function code F; Aspartate carbamoyltransferase, regulatory subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyrI family [H]

Homologues:

Organism=Escherichia coli, GI1790692, Length=148, Percent_Identity=38.5135135135135, Blast_Score=110, Evalue=3e-26,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 440 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020545
- InterPro:   IPR002801
- InterPro:   IPR020542
- ProDom:   PD006194 [H]

Pfam domain/function: PF01948 PyrI; PF02748 PyrI_C [H]

EC number: 2.1.3.2

Molecular weight: Translated: 16715; Mature: 16715

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRELKVKPIENGTVIDHISGSKALKVYKILNIEEKLPITLALNVPSKKGVTKDILKIEG
CCCCEEEEECCCCEEEEECCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCCHHHHEECC
LELSKDDVNKIALISPDATINIIKEGKVIKKFKVDIPKRIDGIIKCTNPNCITNKENIES
CEECCCCCCEEEEECCCCEEEEEECCCEEEEEECCCCCCCCEEEEECCCCEECCCCCCHH
RFSIEQKNTLKIRCEYCEKFINSIIISK
HEEECCCCEEEEEHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKRELKVKPIENGTVIDHISGSKALKVYKILNIEEKLPITLALNVPSKKGVTKDILKIEG
CCCCEEEEECCCCEEEEECCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCCHHHHEECC
LELSKDDVNKIALISPDATINIIKEGKVIKKFKVDIPKRIDGIIKCTNPNCITNKENIES
CEECCCCCCEEEEECCCCEEEEEECCCEEEEEECCCCCCCCEEEEECCCCEECCCCCCHH
RFSIEQKNTLKIRCEYCEKFINSIIISK
HEEECCCCEEEEEHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: carbamoyl phosphate; L-aspartate

Specific reaction: carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA