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The map label for this gene is atpD [H]

Identifier: 45358609

GI number: 45358609

Start: 1039959

End: 1040603

Strand: Direct

Name: atpD [H]

Synonym: MMP1046

Alternate gene names: 45358609

Gene position: 1039959-1040603 (Clockwise)

Preceding gene: 45358608

Following gene: 45358610

Centisome position: 62.61

GC content: 36.28

Gene sequence:

>645_bases
ATGGCAGACGTAAACCCTACAAGAATGGAACTTCTAAAGTTGAAAGGAAAAATTAAACTTGCAGAAAAAGGGCACAAACT
CTTGAAACAGAAAAGAGACGCCCTTATGATGGAGTTTTTTGAAATCCTTGATCAAGCTTCTGGAATAAGAGACAAAGTAA
ATGATGCTCTTTCACAAGCATACAAAGACTTGATAATGGCTCAGGCAGTAATGGGTACTTTATCAGTTAAAGAAGCTTCA
TTTGCAGCTAAAAATAATGACATCGACCTAGATGTGGACATGAGAAACATCATGGGTATCGATGTTCCAGTATTTGAAAT
TTCAAACGTAAAAAGAGACATTTCAACTAGAGGTTACAGCCCTTACGGAGTTTCCTCAAAATTGGATGAAGCTGCAAAGA
ACTTCGAAGAAGCTTTAGAACTTATTACAGAACTTGCAGAAATCGAAACTTCGATAAAATTACTCGCTCAGGAAATCATC
ACAACAAAAAGAAGAGTTAACGCTCTTGAATACGTTGTAATTCCAAAAATGAACGAAACCAAAAAATACATCGCTATGAG
ACTTGAAGAGATGGAGAGGGAAAACTTCTTCAGATTGAAAATCATTAAAGCGAGAATGGACGCTAAAGAAGCTGAAGAAG
CATAA

Upstream 100 bases:

>100_bases
GAACTCAAGAGAGTTTCCGATGAATTAATCGAAAAATACTTACCTAAAAAATAATTCAGAAGCTGAATTATTCCCATTTT
ATTAAACTAGGGGGATAGCA

Downstream 100 bases:

>100_bases
TTCAACATCGTTGGTGGTTTTATGTTCAGAATTACTGGAAAAATTAAGGAAATTGAAGATAAAATTGAAGGCAAAAAACA
GGAAGGGGCTAAACTAGAAA

Product: V-type ATP synthase subunit D

Products: ADP; phosphate; H+

Alternate protein names: V-ATPase subunit D [H]

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MADVNPTRMELLKLKGKIKLAEKGHKLLKQKRDALMMEFFEILDQASGIRDKVNDALSQAYKDLIMAQAVMGTLSVKEAS
FAAKNNDIDLDVDMRNIMGIDVPVFEISNVKRDISTRGYSPYGVSSKLDEAAKNFEEALELITELAEIETSIKLLAQEII
TTKRRVNALEYVVIPKMNETKKYIAMRLEEMERENFFRLKIIKARMDAKEAEEA

Sequences:

>Translated_214_residues
MADVNPTRMELLKLKGKIKLAEKGHKLLKQKRDALMMEFFEILDQASGIRDKVNDALSQAYKDLIMAQAVMGTLSVKEAS
FAAKNNDIDLDVDMRNIMGIDVPVFEISNVKRDISTRGYSPYGVSSKLDEAAKNFEEALELITELAEIETSIKLLAQEII
TTKRRVNALEYVVIPKMNETKKYIAMRLEEMERENFFRLKIIKARMDAKEAEEA
>Mature_213_residues
ADVNPTRMELLKLKGKIKLAEKGHKLLKQKRDALMMEFFEILDQASGIRDKVNDALSQAYKDLIMAQAVMGTLSVKEASF
AAKNNDIDLDVDMRNIMGIDVPVFEISNVKRDISTRGYSPYGVSSKLDEAAKNFEEALELITELAEIETSIKLLAQEIIT
TKRRVNALEYVVIPKMNETKKYIAMRLEEMERENFFRLKIIKARMDAKEAEEA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane [H]

COG id: COG1394

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit D

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase D subunit family [H]

Homologues:

Organism=Homo sapiens, GI7706757, Length=204, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17553636, Length=210, Percent_Identity=33.8095238095238, Blast_Score=104, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6320784, Length=216, Percent_Identity=31.0185185185185, Blast_Score=86, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21355551, Length=217, Percent_Identity=35.0230414746544, Blast_Score=104, Evalue=4e-23,
Organism=Drosophila melanogaster, GI20128937, Length=204, Percent_Identity=32.3529411764706, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI20129907, Length=219, Percent_Identity=30.1369863013699, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002699 [H]

Pfam domain/function: PF01813 ATP-synt_D [H]

EC number: 3.6.3.14

Molecular weight: Translated: 24395; Mature: 24264

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADVNPTRMELLKLKGKIKLAEKGHKLLKQKRDALMMEFFEILDQASGIRDKVNDALSQA
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
YKDLIMAQAVMGTLSVKEASFAAKNNDIDLDVDMRNIMGIDVPVFEISNVKRDISTRGYS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCCCCCHHHHHHHHHHHHHCCCC
PYGVSSKLDEAAKNFEEALELITELAEIETSIKLLAQEIITTKRRVNALEYVVIPKMNET
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHH
KKYIAMRLEEMERENFFRLKIIKARMDAKEAEEA
HHHHHHHHHHHHHCCHHHHHHHHHHHCHHHCCCC
>Mature Secondary Structure 
ADVNPTRMELLKLKGKIKLAEKGHKLLKQKRDALMMEFFEILDQASGIRDKVNDALSQA
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
YKDLIMAQAVMGTLSVKEASFAAKNNDIDLDVDMRNIMGIDVPVFEISNVKRDISTRGYS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCCCCCHHHHHHHHHHHHHCCCC
PYGVSSKLDEAAKNFEEALELITELAEIETSIKLLAQEIITTKRRVNALEYVVIPKMNET
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHH
KKYIAMRLEEMERENFFRLKIIKARMDAKEAEEA
HHHHHHHHHHHHHCCHHHHHHHHHHHCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA