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The map label for this gene is atpA [H]

Identifier: 45358607

GI number: 45358607

Start: 1036729

End: 1038489

Strand: Direct

Name: atpA [H]

Synonym: MMP1044

Alternate gene names: 45358607

Gene position: 1036729-1038489 (Clockwise)

Preceding gene: 45358606

Following gene: 45358608

Centisome position: 62.41

GC content: 40.77

Gene sequence:

>1761_bases
ATGGTCGTCGGTAAAATTATCAAAATATCCGGTCCGGTTGTTGTTGCCGAAGGCATGAAAGGTTCCCAGATGTTCGAAGT
GGTTAAAGTAGGAAACGAAGGTTTAACCGGGGAAATCATTCAGTTAACTGAGGACGAAGCAATCATTCAGGTTTATGAAG
AAACTGCTGGTATCAAACCAGGAGAAGGAGTTGAAGGTACTGGTGCTCCATTATCAGTAGAGCTCGGCCCTGGTATGTTA
AAAGCAATGTACGATGGTATTCAAAGACCTTTAAACGAAATCGAAAATGCTACAGATTCAATTTACATCCCAAGAGGAGT
AAGTGTTCCATCAATCTCAAGAGAAATTAAATGGGACTTTGAACCAACTGCAGCAGCTGGAGATGAAGTTATAACTGGGG
ACGTTATCGGTACAGTTCAAGAAACTGCATCAATCGTTCACAAAATCATGATTCCTTTCGGAGTTAGCGGTAAAATTAAA
GAAATTAAAGCAGGCAGCTTCACTGTTGAAGAAACAGTTGCAGTTGTTGAAACCGCTGAAGGCGAAAAAGAAATCATGAT
GATGCAAAAATGGCCTGTAAGAAAGCCAAGACCATCAAAAGGAAAACAAGCTCCAGTAATTCCATTAATTACTGGTCAAA
GAGTTGAAGATACATTCTTCGGACTTGCAAAAGGTGGTGCTTCAGCAATTCCAGGTCCATTTGGAAGTGGAAAAACTGTT
ACACAACACCAGCTTGCTAAATGGTCTGATGTGGATGTTGTGGTATACATCGGTTGTGGAGAAAGAGGTAACGAGATGAC
AGAAGTTATCGAAGAGTTCCCACACTTAGATGATATCAAAACAGGAAACAAATTGATGGACAGGACCGTATTAATTGCAA
ATACATCAAACATGCCGGTAGCTGCTAGGGAAGCTTCAGTATATACTGGAATTACAATTGCAGAATACTTCAGAGACCAA
GGACTTGGTGTTCTCTTAACTGCTGACTCAACATCAAGATGGGCAGAAGCAATGAGAGAGATCTCAGGTAGGCTTGAAGA
AATGCCTGGGGAAGAAGGATACCCTGCATACCTTTCATCAAAACTCGCTCAGTTCTACGAAAGAGCAGGCAGAGTTGAAT
GTTTAGGTTCAGAAAACAAACAAGGATTCGTATGTATTGTAGGTGCAGTATCACCACCAGGTGGTGACTTCTCAGAACCA
GTTACATCAAACACATTAAGAATCGTTAAGGTGTTCTGGGCATTAGATGCAAACCTTGCAAGAAGAAGACACTTCCCTGC
AATCAACTGGTTAACAAGTTACTCACTCTATATTGACGACATCGCTGGCTGGTGGCAACAAAACACCGCAGCAGACTGGA
GATCATTAAGAGATGAAGCAATGAGCTTACTCCAAAAAGAAGCTGAGCTCCAAGAAATCGTTCAACTTGTTGGTCCAGAT
GCACTTCCAGACAGAGAAAGAGTTATCTTAGAAATTGCAAGAATGTTAAGAGAAGACTTCTTACAGCAAGATGCATACCA
CGAAGTAGACAGCTACTGTTCACCATTAAAACAGTACAACATGTTGAAAATCATCATGACGTTCTACAAGAAAGGATTAG
ATGCAGTTGCTAAAGGTGCTGACCCAGCAGGCATTTCAGCTGTTACTGTAAAAGGAGACATTGCAAGAATGAAATACCTG
ACTGATGACGAATTCATAAACACGAAAGTACCTGAAATCATTAACAAAATGGAATCCGAATTAGGTGCTTTAATCAAATA
A

Upstream 100 bases:

>100_bases
TCCTGACAAAAACGGTCCTATTGTCAGAGAAAATGATCCTGTGAAAGTATTAGTAAGAAACGCTGTTGGTGTTGACATTA
AGTAATTCTGAGGTGAAAAT

Downstream 100 bases:

>100_bases
CCTAATTTAATTTTAAACTGTAAGGAGGGTTATCATGGACGCTATGCAGAAAACCATAGAATACACATCCGTCTCCAGAA
TTGCTGGTCCTTTAATGGTT

Product: V-type ATP synthase subunit A

Products: NA

Alternate protein names: V-ATPase subunit A [H]

Number of amino acids: Translated: 586; Mature: 586

Protein sequence:

>586_residues
MVVGKIIKISGPVVVAEGMKGSQMFEVVKVGNEGLTGEIIQLTEDEAIIQVYEETAGIKPGEGVEGTGAPLSVELGPGML
KAMYDGIQRPLNEIENATDSIYIPRGVSVPSISREIKWDFEPTAAAGDEVITGDVIGTVQETASIVHKIMIPFGVSGKIK
EIKAGSFTVEETVAVVETAEGEKEIMMMQKWPVRKPRPSKGKQAPVIPLITGQRVEDTFFGLAKGGASAIPGPFGSGKTV
TQHQLAKWSDVDVVVYIGCGERGNEMTEVIEEFPHLDDIKTGNKLMDRTVLIANTSNMPVAAREASVYTGITIAEYFRDQ
GLGVLLTADSTSRWAEAMREISGRLEEMPGEEGYPAYLSSKLAQFYERAGRVECLGSENKQGFVCIVGAVSPPGGDFSEP
VTSNTLRIVKVFWALDANLARRRHFPAINWLTSYSLYIDDIAGWWQQNTAADWRSLRDEAMSLLQKEAELQEIVQLVGPD
ALPDRERVILEIARMLREDFLQQDAYHEVDSYCSPLKQYNMLKIIMTFYKKGLDAVAKGADPAGISAVTVKGDIARMKYL
TDDEFINTKVPEIINKMESELGALIK

Sequences:

>Translated_586_residues
MVVGKIIKISGPVVVAEGMKGSQMFEVVKVGNEGLTGEIIQLTEDEAIIQVYEETAGIKPGEGVEGTGAPLSVELGPGML
KAMYDGIQRPLNEIENATDSIYIPRGVSVPSISREIKWDFEPTAAAGDEVITGDVIGTVQETASIVHKIMIPFGVSGKIK
EIKAGSFTVEETVAVVETAEGEKEIMMMQKWPVRKPRPSKGKQAPVIPLITGQRVEDTFFGLAKGGASAIPGPFGSGKTV
TQHQLAKWSDVDVVVYIGCGERGNEMTEVIEEFPHLDDIKTGNKLMDRTVLIANTSNMPVAAREASVYTGITIAEYFRDQ
GLGVLLTADSTSRWAEAMREISGRLEEMPGEEGYPAYLSSKLAQFYERAGRVECLGSENKQGFVCIVGAVSPPGGDFSEP
VTSNTLRIVKVFWALDANLARRRHFPAINWLTSYSLYIDDIAGWWQQNTAADWRSLRDEAMSLLQKEAELQEIVQLVGPD
ALPDRERVILEIARMLREDFLQQDAYHEVDSYCSPLKQYNMLKIIMTFYKKGLDAVAKGADPAGISAVTVKGDIARMKYL
TDDEFINTKVPEIINKMESELGALIK
>Mature_586_residues
MVVGKIIKISGPVVVAEGMKGSQMFEVVKVGNEGLTGEIIQLTEDEAIIQVYEETAGIKPGEGVEGTGAPLSVELGPGML
KAMYDGIQRPLNEIENATDSIYIPRGVSVPSISREIKWDFEPTAAAGDEVITGDVIGTVQETASIVHKIMIPFGVSGKIK
EIKAGSFTVEETVAVVETAEGEKEIMMMQKWPVRKPRPSKGKQAPVIPLITGQRVEDTFFGLAKGGASAIPGPFGSGKTV
TQHQLAKWSDVDVVVYIGCGERGNEMTEVIEEFPHLDDIKTGNKLMDRTVLIANTSNMPVAAREASVYTGITIAEYFRDQ
GLGVLLTADSTSRWAEAMREISGRLEEMPGEEGYPAYLSSKLAQFYERAGRVECLGSENKQGFVCIVGAVSPPGGDFSEP
VTSNTLRIVKVFWALDANLARRRHFPAINWLTSYSLYIDDIAGWWQQNTAADWRSLRDEAMSLLQKEAELQEIVQLVGPD
ALPDRERVILEIARMLREDFLQQDAYHEVDSYCSPLKQYNMLKIIMTFYKKGLDAVAKGADPAGISAVTVKGDIARMKYL
TDDEFINTKVPEIINKMESELGALIK

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit [H]

COG id: COG1155

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI19913424, Length=542, Percent_Identity=52.0295202952029, Blast_Score=565, Evalue=1e-161,
Organism=Homo sapiens, GI32189394, Length=304, Percent_Identity=29.9342105263158, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI19913428, Length=225, Percent_Identity=29.3333333333333, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI19913426, Length=244, Percent_Identity=28.2786885245902, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI50345984, Length=351, Percent_Identity=25.0712250712251, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI4757810, Length=351, Percent_Identity=25.0712250712251, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1790170, Length=374, Percent_Identity=27.5401069518717, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1788251, Length=227, Percent_Identity=30.3964757709251, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1790172, Length=235, Percent_Identity=26.3829787234043, Blast_Score=73, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17565854, Length=538, Percent_Identity=54.089219330855, Blast_Score=587, Evalue=1e-168,
Organism=Caenorhabditis elegans, GI25144756, Length=302, Percent_Identity=29.1390728476821, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17510931, Length=222, Percent_Identity=29.7297297297297, Blast_Score=99, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17570191, Length=244, Percent_Identity=27.8688524590164, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71988080, Length=307, Percent_Identity=24.4299674267101, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71988063, Length=307, Percent_Identity=24.4299674267101, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71988074, Length=307, Percent_Identity=24.4299674267101, Blast_Score=73, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320016, Length=311, Percent_Identity=51.1254019292604, Blast_Score=323, Evalue=4e-89,
Organism=Saccharomyces cerevisiae, GI6322581, Length=326, Percent_Identity=27.9141104294479, Blast_Score=103, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6319603, Length=243, Percent_Identity=27.9835390946502, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319370, Length=344, Percent_Identity=24.1279069767442, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20129479, Length=593, Percent_Identity=49.0725126475548, Blast_Score=583, Evalue=1e-166,
Organism=Drosophila melanogaster, GI24583988, Length=541, Percent_Identity=51.9408502772643, Blast_Score=571, Evalue=1e-163,
Organism=Drosophila melanogaster, GI24583986, Length=541, Percent_Identity=51.9408502772643, Blast_Score=571, Evalue=1e-163,
Organism=Drosophila melanogaster, GI24583984, Length=541, Percent_Identity=51.9408502772643, Blast_Score=571, Evalue=1e-163,
Organism=Drosophila melanogaster, GI24583992, Length=541, Percent_Identity=51.7560073937153, Blast_Score=561, Evalue=1e-160,
Organism=Drosophila melanogaster, GI28574560, Length=300, Percent_Identity=30.6666666666667, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24638766, Length=300, Percent_Identity=29.6666666666667, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI281361666, Length=244, Percent_Identity=27.4590163934426, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24646341, Length=244, Percent_Identity=27.4590163934426, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI17136796, Length=244, Percent_Identity=27.4590163934426, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24658560, Length=280, Percent_Identity=23.9285714285714, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005726
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- InterPro:   IPR022878 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 64194; Mature: 64194

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVGKIIKISGPVVVAEGMKGSQMFEVVKVGNEGLTGEIIQLTEDEAIIQVYEETAGIKP
CCCEEEEEECCCEEEECCCCCHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHCCCCC
GEGVEGTGAPLSVELGPGMLKAMYDGIQRPLNEIENATDSIYIPRGVSVPSISREIKWDF
CCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCEEECC
EPTAAAGDEVITGDVIGTVQETASIVHKIMIPFGVSGKIKEIKAGSFTVEETVAVVETAE
CCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEEHHHHHHHHCCCC
GEKEIMMMQKWPVRKPRPSKGKQAPVIPLITGQRVEDTFFGLAKGGASAIPGPFGSGKTV
CCHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCH
TQHQLAKWSDVDVVVYIGCGERGNEMTEVIEEFPHLDDIKTGNKLMDRTVLIANTSNMPV
HHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCHHHCCEEEEEECCCCCE
AAREASVYTGITIAEYFRDQGLGVLLTADSTSRWAEAMREISGRLEEMPGEEGYPAYLSS
EECCCHHHCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
KLAQFYERAGRVECLGSENKQGFVCIVGAVSPPGGDFSEPVTSNTLRIVKVFWALDANLA
HHHHHHHHCCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RRRHFPAINWLTSYSLYIDDIAGWWQQNTAADWRSLRDEAMSLLQKEAELQEIVQLVGPD
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ALPDRERVILEIARMLREDFLQQDAYHEVDSYCSPLKQYNMLKIIMTFYKKGLDAVAKGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DPAGISAVTVKGDIARMKYLTDDEFINTKVPEIINKMESELGALIK
CCCCCEEEEECCCHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVVGKIIKISGPVVVAEGMKGSQMFEVVKVGNEGLTGEIIQLTEDEAIIQVYEETAGIKP
CCCEEEEEECCCEEEECCCCCHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHCCCCC
GEGVEGTGAPLSVELGPGMLKAMYDGIQRPLNEIENATDSIYIPRGVSVPSISREIKWDF
CCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCEEECC
EPTAAAGDEVITGDVIGTVQETASIVHKIMIPFGVSGKIKEIKAGSFTVEETVAVVETAE
CCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEEHHHHHHHHCCCC
GEKEIMMMQKWPVRKPRPSKGKQAPVIPLITGQRVEDTFFGLAKGGASAIPGPFGSGKTV
CCHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCH
TQHQLAKWSDVDVVVYIGCGERGNEMTEVIEEFPHLDDIKTGNKLMDRTVLIANTSNMPV
HHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCHHHCCEEEEEECCCCCE
AAREASVYTGITIAEYFRDQGLGVLLTADSTSRWAEAMREISGRLEEMPGEEGYPAYLSS
EECCCHHHCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
KLAQFYERAGRVECLGSENKQGFVCIVGAVSPPGGDFSEPVTSNTLRIVKVFWALDANLA
HHHHHHHHCCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RRRHFPAINWLTSYSLYIDDIAGWWQQNTAADWRSLRDEAMSLLQKEAELQEIVQLVGPD
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ALPDRERVILEIARMLREDFLQQDAYHEVDSYCSPLKQYNMLKIIMTFYKKGLDAVAKGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DPAGISAVTVKGDIARMKYLTDDEFINTKVPEIINKMESELGALIK
CCCCCEEEEECCCHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA