Click here to switch to the map view.

The map label for this gene is 45358159

Identifier: 45358159

GI number: 45358159

Start: 591868

End: 593298

Strand: Direct

Name: 45358159

Synonym: MMP0596

Alternate gene names: NA

Gene position: 591868-593298 (Clockwise)

Preceding gene: 45358152

Following gene: 45358160

Centisome position: 35.63

GC content: 36.2

Gene sequence:

>1431_bases
ATGTTATTCATTGCCTTTGCACCGTTTGGAGCATTTGCACTTGAAGCGAACTCGAAAAACGACGGATATTCATTAGACGA
CATCAAATATTACAAAATATTTGAAAACGAGGATATCCCAAAAATAATGTATGCGCTGAGACAGGGCGATTTTGAAATAA
TCGCTGAATTGAAAAACGAATGGGAAATTGAAGAAGAAGATGTTAGTTTTGAGTATACTACTTCTAAAAATCCACTTGGA
GAACTTATTCGAGATAATTTATATGAATTAGGTCAAAAATACGAAGTTTTTGAAGATGAATCAGATTTTGTTTCAAAAAT
GAACGTTTGGGCAACTGCTTTCACAAAATCGATGATGAAAAAATCATCAGAACAGAAAGATAAATTGATAGTTCAAACAG
TAAATGCCCTCGATAACCTTGATGAAACTCTAAACTTGTTTTCAGAAAGACTTAGAGAATGGTATTCACTATACTTTCCT
GAAATGGACAATATTGTTAAGAAACACGATATTTATGTGAGTTTAGTTTCCGAATATGGGGACAGGGAAGAATATACTCG
AACAAAACTTAAAAAAACGATGCCTTCAAACGTTGCAAGAACAATTTCGCTTGCTGCAAAAGAATCAATGGGTGCAGATG
TATCCGAATTTGATTTAAAAATCATGAAAAACCTTGCAGATGAAATAAAGAGCATGTATGAATACAGGGAAAGCTTGCAA
GAATATTTGGAAACTTCAATGAATGAAATTGCTCCAAATTTAACGAAAGTTGCAGGTGCATCACTTGGTGCAAGATTGAT
AAGCCTTGCAGGTGGAATTGAAAGACTTTTAAGACTTCCTGCATCAACAATACAAGTTATCGGTGCAGAAAAAGCATTAT
TTGCACACTTAAGAGAAAGAGCACTACCTCCTAAACACGGAGTTATTTTCCAGCACCCGCTTATTCAGGGAAGTCCTTGG
TGGATACACGGAAAAATTGCAAGAGCAATTTCATGCAAAATTTCAATTGCGATAAGGGCAGATGCTTTTGGAAATGATAT
TTCAGACATGTTAATTGAAGACATGAATAAAAAAGTAGCTGAAATAAAAGAAAAATTCCCTGAACCAACGAGAAAAAGAA
GACCAAGACCAGATACAAGAAGTTTCGGTAATAAAGGCGGCCAAGATCGGGATAGAAGGTCACAGGGTGACAGAAAACCA
TCCGGTAATAGGGGCGACTCTAAAAAAGGTGGAAAACCATTTGGTAAGAAACCTGCTGGAAAAGACGACAGACGAGATAA
CAGGAAAGGCGATAGGAAACCATTTGGCGGAAAACCAAAAAATAGCGGAAATCAGCCTCCAAAGGAAAGATCTGGCGAAA
AAAGAAGAGATTCGACAAAAAAAGTTAAAGCTGAGCGAAAAGTAATCGGAAAAACTTCCTCACAGAATTAA

Upstream 100 bases:

>100_bases
GTTTTACGTAGTATTAAATACCCGAATGATTAAATAGTTTCAGATTGATTAGAAGTTAAGAGTACATTTTTCATGGATTT
ATAAATTTTTAGGTGATTTT

Downstream 100 bases:

>100_bases
GCCATATGGTGAGTTAAATGGAAAAAATTAGGGTAAAAGAAATTTTTGATAACGTATATTCAGTAGATTTTGGAGACGGA
CTTAAAAGAATTGCTACAAA

Product: C/D box methylation guide ribonucleoprotein complex aNOP56 subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MLFIAFAPFGAFALEANSKNDGYSLDDIKYYKIFENEDIPKIMYALRQGDFEIIAELKNEWEIEEEDVSFEYTTSKNPLG
ELIRDNLYELGQKYEVFEDESDFVSKMNVWATAFTKSMMKKSSEQKDKLIVQTVNALDNLDETLNLFSERLREWYSLYFP
EMDNIVKKHDIYVSLVSEYGDREEYTRTKLKKTMPSNVARTISLAAKESMGADVSEFDLKIMKNLADEIKSMYEYRESLQ
EYLETSMNEIAPNLTKVAGASLGARLISLAGGIERLLRLPASTIQVIGAEKALFAHLRERALPPKHGVIFQHPLIQGSPW
WIHGKIARAISCKISIAIRADAFGNDISDMLIEDMNKKVAEIKEKFPEPTRKRRPRPDTRSFGNKGGQDRDRRSQGDRKP
SGNRGDSKKGGKPFGKKPAGKDDRRDNRKGDRKPFGGKPKNSGNQPPKERSGEKRRDSTKKVKAERKVIGKTSSQN

Sequences:

>Translated_476_residues
MLFIAFAPFGAFALEANSKNDGYSLDDIKYYKIFENEDIPKIMYALRQGDFEIIAELKNEWEIEEEDVSFEYTTSKNPLG
ELIRDNLYELGQKYEVFEDESDFVSKMNVWATAFTKSMMKKSSEQKDKLIVQTVNALDNLDETLNLFSERLREWYSLYFP
EMDNIVKKHDIYVSLVSEYGDREEYTRTKLKKTMPSNVARTISLAAKESMGADVSEFDLKIMKNLADEIKSMYEYRESLQ
EYLETSMNEIAPNLTKVAGASLGARLISLAGGIERLLRLPASTIQVIGAEKALFAHLRERALPPKHGVIFQHPLIQGSPW
WIHGKIARAISCKISIAIRADAFGNDISDMLIEDMNKKVAEIKEKFPEPTRKRRPRPDTRSFGNKGGQDRDRRSQGDRKP
SGNRGDSKKGGKPFGKKPAGKDDRRDNRKGDRKPFGGKPKNSGNQPPKERSGEKRRDSTKKVKAERKVIGKTSSQN
>Mature_476_residues
MLFIAFAPFGAFALEANSKNDGYSLDDIKYYKIFENEDIPKIMYALRQGDFEIIAELKNEWEIEEEDVSFEYTTSKNPLG
ELIRDNLYELGQKYEVFEDESDFVSKMNVWATAFTKSMMKKSSEQKDKLIVQTVNALDNLDETLNLFSERLREWYSLYFP
EMDNIVKKHDIYVSLVSEYGDREEYTRTKLKKTMPSNVARTISLAAKESMGADVSEFDLKIMKNLADEIKSMYEYRESLQ
EYLETSMNEIAPNLTKVAGASLGARLISLAGGIERLLRLPASTIQVIGAEKALFAHLRERALPPKHGVIFQHPLIQGSPW
WIHGKIARAISCKISIAIRADAFGNDISDMLIEDMNKKVAEIKEKFPEPTRKRRPRPDTRSFGNKGGQDRDRRSQGDRKP
SGNRGDSKKGGKPFGKKPAGKDDRRDNRKGDRKPFGGKPKNSGNQPPKERSGEKRRDSTKKVKAERKVIGKTSSQN

Specific function: Unknown

COG id: COG1498

COG function: function code J; Protein implicated in ribosomal biogenesis, Nop56p homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Nop domain [H]

Homologues:

Organism=Homo sapiens, GI32483374, Length=368, Percent_Identity=32.0652173913043, Blast_Score=186, Evalue=6e-47,
Organism=Homo sapiens, GI7706254, Length=242, Percent_Identity=40.495867768595, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI221136939, Length=257, Percent_Identity=26.0700389105058, Blast_Score=106, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17509449, Length=245, Percent_Identity=38.7755102040816, Blast_Score=183, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17562296, Length=265, Percent_Identity=33.9622641509434, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17510923, Length=290, Percent_Identity=24.1379310344828, Blast_Score=101, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6324886, Length=247, Percent_Identity=36.4372469635627, Blast_Score=174, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6323226, Length=252, Percent_Identity=33.3333333333333, Blast_Score=151, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6321528, Length=214, Percent_Identity=24.7663551401869, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28572126, Length=292, Percent_Identity=35.958904109589, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI17137636, Length=238, Percent_Identity=37.3949579831933, Blast_Score=172, Evalue=5e-43,
Organism=Drosophila melanogaster, GI21357435, Length=266, Percent_Identity=25.5639097744361, Blast_Score=105, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012976
- InterPro:   IPR002687 [H]

Pfam domain/function: PF01798 Nop; PF08060 NOSIC [H]

EC number: NA

Molecular weight: Translated: 54222; Mature: 54222

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFIAFAPFGAFALEANSKNDGYSLDDIKYYKIFENEDIPKIMYALRQGDFEIIAELKNE
CEEEEEECCCCEEEECCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHC
WEIEEEDVSFEYTTSKNPLGELIRDNLYELGQKYEVFEDESDFVSKMNVWATAFTKSMMK
CCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHH
KSSEQKDKLIVQTVNALDNLDETLNLFSERLREWYSLYFPEMDNIVKKHDIYVSLVSEYG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
DREEYTRTKLKKTMPSNVARTISLAAKESMGADVSEFDLKIMKNLADEIKSMYEYRESLQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EYLETSMNEIAPNLTKVAGASLGARLISLAGGIERLLRLPASTIQVIGAEKALFAHLRER
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ALPPKHGVIFQHPLIQGSPWWIHGKIARAISCKISIAIRADAFGNDISDMLIEDMNKKVA
CCCCCCCEEEECCCCCCCCCEEEHHHHHHEEEEEEEEEECCCCCCCHHHHHHHHHHHHHH
EIKEKFPEPTRKRRPRPDTRSFGNKGGQDRDRRSQGDRKPSGNRGDSKKGGKPFGKKPAG
HHHHHCCCCHHHCCCCCCHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
KDDRRDNRKGDRKPFGGKPKNSGNQPPKERSGEKRRDSTKKVKAERKVIGKTSSQN
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLFIAFAPFGAFALEANSKNDGYSLDDIKYYKIFENEDIPKIMYALRQGDFEIIAELKNE
CEEEEEECCCCEEEECCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHC
WEIEEEDVSFEYTTSKNPLGELIRDNLYELGQKYEVFEDESDFVSKMNVWATAFTKSMMK
CCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHH
KSSEQKDKLIVQTVNALDNLDETLNLFSERLREWYSLYFPEMDNIVKKHDIYVSLVSEYG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
DREEYTRTKLKKTMPSNVARTISLAAKESMGADVSEFDLKIMKNLADEIKSMYEYRESLQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EYLETSMNEIAPNLTKVAGASLGARLISLAGGIERLLRLPASTIQVIGAEKALFAHLRER
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ALPPKHGVIFQHPLIQGSPWWIHGKIARAISCKISIAIRADAFGNDISDMLIEDMNKKVA
CCCCCCCEEEECCCCCCCCCEEEHHHHHHEEEEEEEEEECCCCCCCHHHHHHHHHHHHHH
EIKEKFPEPTRKRRPRPDTRSFGNKGGQDRDRRSQGDRKPSGNRGDSKKGGKPFGKKPAG
HHHHHCCCCHHHCCCCCCHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
KDDRRDNRKGDRKPFGGKPKNSGNQPPKERSGEKRRDSTKKVKAERKVIGKTSSQN
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]