Click here to switch to the map view.

The map label for this gene is serB [C]

Identifier: 45358104

GI number: 45358104

Start: 545781

End: 546422

Strand: Direct

Name: serB [C]

Synonym: MMP0541

Alternate gene names: 45358104

Gene position: 545781-546422 (Clockwise)

Preceding gene: 45358103

Following gene: 45358105

Centisome position: 32.86

GC content: 33.49

Gene sequence:

>642_bases
ATGACAGATAATTTAGTAAAAAAACTTATTTTATTTGATTTAGATAGTACACTTGCGGACTGCGAGGTAATTGATGAAAT
TGCAAAATTTGCAGGTGTCGAATCAGAAATTAAAAAAATAACTAACGAAGCAATGAAAGGCAATATAAATTTTGAAGAAT
CATTAAGAAGACGGGTAAGGCTATTAAAAGGAATTCCTGTTGAAAAACTTAATAAATTTGCAGAAACAATTCCTGTAATG
AATGGTGCGCCGGAATTAATATTGGAACTCAAAAAACAAGGGTATGTTACAGCCGTTGTCAGCGGTGGATTTGATTTTGG
GGCTGAACATGTTAAAAAAGTACTGGGACTTGATTATTCTTATGCAAATACTCTTTTGTCCGAAAATGGAATTTTAACAG
GCGAAGTAATCGGCCCAGTAATGAGTGAAACTGCTAAAGGCGACATATTGGAAAAAATTGCAGCAAATGAAAATATTTCT
CTTAAAAACACGGTTGTAGTAGGGGATGGGGCAAACGACATAAGTATGTTTGAGAAAGCAGGCTTTAAAATAGCTTTCTG
TGCGAAAGAAATTTTAAGATCGAAGGCAGACATTTGTATCGATAAAAAGGACTTAAAAGAAATATTGAACCACATTAACT
AA

Upstream 100 bases:

>100_bases
AGACTTAGGCGATGTTTTAGAAAAATACAAAATCGTTGCTGAAAGAATCGGATGCTTAAAATAATTATTTTTACTTTTCT
TTTTACCGATTGGTGGAATA

Downstream 100 bases:

>100_bases
CTTTTTTCAGCTTTTTTGACTTAAAACAGCTTTTTTCGAACTTTTTTGCTTTGTTTTAAATAAAAATATTTATATATCTT
ACAACAAAAATTTATAATAT

Product: phosphoserine phosphatase SerB

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MTDNLVKKLILFDLDSTLADCEVIDEIAKFAGVESEIKKITNEAMKGNINFEESLRRRVRLLKGIPVEKLNKFAETIPVM
NGAPELILELKKQGYVTAVVSGGFDFGAEHVKKVLGLDYSYANTLLSENGILTGEVIGPVMSETAKGDILEKIAANENIS
LKNTVVVGDGANDISMFEKAGFKIAFCAKEILRSKADICIDKKDLKEILNHIN

Sequences:

>Translated_213_residues
MTDNLVKKLILFDLDSTLADCEVIDEIAKFAGVESEIKKITNEAMKGNINFEESLRRRVRLLKGIPVEKLNKFAETIPVM
NGAPELILELKKQGYVTAVVSGGFDFGAEHVKKVLGLDYSYANTLLSENGILTGEVIGPVMSETAKGDILEKIAANENIS
LKNTVVVGDGANDISMFEKAGFKIAFCAKEILRSKADICIDKKDLKEILNHIN
>Mature_212_residues
TDNLVKKLILFDLDSTLADCEVIDEIAKFAGVESEIKKITNEAMKGNINFEESLRRRVRLLKGIPVEKLNKFAETIPVMN
GAPELILELKKQGYVTAVVSGGFDFGAEHVKKVLGLDYSYANTLLSENGILTGEVIGPVMSETAKGDILEKIAANENISL
KNTVVVGDGANDISMFEKAGFKIAFCAKEILRSKADICIDKKDLKEILNHIN

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=182, Percent_Identity=30.7692307692308, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1790849, Length=197, Percent_Identity=40.6091370558376, Blast_Score=146, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI115534456, Length=217, Percent_Identity=31.7972350230415, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI115534454, Length=217, Percent_Identity=31.7972350230415, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI115534458, Length=219, Percent_Identity=31.5068493150685, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321647, Length=205, Percent_Identity=40, Blast_Score=142, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24661601, Length=188, Percent_Identity=28.1914893617021, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 23347; Mature: 23216

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDNLVKKLILFDLDSTLADCEVIDEIAKFAGVESEIKKITNEAMKGNINFEESLRRRVR
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
LLKGIPVEKLNKFAETIPVMNGAPELILELKKQGYVTAVVSGGFDFGAEHVKKVLGLDYS
HHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCCCHH
YANTLLSENGILTGEVIGPVMSETAKGDILEKIAANENISLKNTVVVGDGANDISMFEKA
HHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHC
GFKIAFCAKEILRSKADICIDKKDLKEILNHIN
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TDNLVKKLILFDLDSTLADCEVIDEIAKFAGVESEIKKITNEAMKGNINFEESLRRRVR
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
LLKGIPVEKLNKFAETIPVMNGAPELILELKKQGYVTAVVSGGFDFGAEHVKKVLGLDYS
HHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCCCHH
YANTLLSENGILTGEVIGPVMSETAKGDILEKIAANENISLKNTVVVGDGANDISMFEKA
HHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHC
GFKIAFCAKEILRSKADICIDKKDLKEILNHIN
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 11342136; 12051918 [H]