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The map label for this gene is 45357950

Identifier: 45357950

GI number: 45357950

Start: 385673

End: 386296

Strand: Direct

Name: 45357950

Synonym: MMP0387

Alternate gene names: NA

Gene position: 385673-386296 (Clockwise)

Preceding gene: 45357946

Following gene: 45357959

Centisome position: 23.22

GC content: 33.49

Gene sequence:

>624_bases
TTGGGTGGTATCATCAATAATAAAAATATTCTTGAATGGACTGTATTTTTATTTGTCTTTCTTATTGTGTGGACACATGT
CAATGTTGTGGTCTCAGACAGCATGGTTCCAGTAATGACGAGAGGCGATTTTGTAGTTGTGGAAAATTCTTTATTTGAGT
TTGACCCCGAAAGCGTCTCAGTAGGTGATATAATAGTTTATAGTGCCCACTGGACCAATGCTGGAGAAAATAAAATAATA
AACCAAGACTTATCGATAAACGGGCGAAATTTAAATTATTATGAGTTAAATTCCCGGGAAAGTATGATTTATAACCTGCC
AATAATTTCGAGTTATTCGCCAACAACGCCTGTAATTCACAGGGTAATTGATACGTGGACTGATTCTGAGGGAAACAAAT
ATTACATTACAAAAGGGGATAATAACCCGACGTATGATCCAGAATTAATACGTGCAGAACAAGTTAGGCAGAGGGTAGTT
GAATTAAATGACGAACCATTTATAATTCCGTATTTGGGACACATTTCAATAATTCTAAAAGAGAATTTGATTATATTTGT
GATATTGCTTGTAATATGGATGTATTATGATTACAGAAAAGAAAAAGTTGCAAAAAATAATTAA

Upstream 100 bases:

>100_bases
CTATATGAAATCATGACTAAACCCAAAACCACAATGTAATTTATATTAGCTTACCTATATTATTATTAAGAATCCAAAAA
TCGCTAAATTAAATTAGAGT

Downstream 100 bases:

>100_bases
AAACTAAATAAAACCAAAAAATATTAATTTTTTAAAGTAATTCTTTAAAATGTCTCAAGAGCGATGGTGCTTTTGCAACT
ATTTTAATTGCGAGCTTTCC

Product: microsomal signal peptidase 21 KD subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MGGIINNKNILEWTVFLFVFLIVWTHVNVVVSDSMVPVMTRGDFVVVENSLFEFDPESVSVGDIIVYSAHWTNAGENKII
NQDLSINGRNLNYYELNSRESMIYNLPIISSYSPTTPVIHRVIDTWTDSEGNKYYITKGDNNPTYDPELIRAEQVRQRVV
ELNDEPFIIPYLGHISIILKENLIIFVILLVIWMYYDYRKEKVAKNN

Sequences:

>Translated_207_residues
MGGIINNKNILEWTVFLFVFLIVWTHVNVVVSDSMVPVMTRGDFVVVENSLFEFDPESVSVGDIIVYSAHWTNAGENKII
NQDLSINGRNLNYYELNSRESMIYNLPIISSYSPTTPVIHRVIDTWTDSEGNKYYITKGDNNPTYDPELIRAEQVRQRVV
ELNDEPFIIPYLGHISIILKENLIIFVILLVIWMYYDYRKEKVAKNN
>Mature_206_residues
GGIINNKNILEWTVFLFVFLIVWTHVNVVVSDSMVPVMTRGDFVVVENSLFEFDPESVSVGDIIVYSAHWTNAGENKIIN
QDLSINGRNLNYYELNSRESMIYNLPIISSYSPTTPVIHRVIDTWTDSEGNKYYITKGDNNPTYDPELIRAEQVRQRVVE
LNDEPFIIPYLGHISIILKENLIIFVILLVIWMYYDYRKEKVAKNN

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056
- InterPro:   IPR001733 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: 3.4.21.89

Molecular weight: Translated: 24013; Mature: 23882

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGIINNKNILEWTVFLFVFLIVWTHVNVVVSDSMVPVMTRGDFVVVENSLFEFDPESVS
CCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEECCEEEEEECCCEEEEECCEEEECCCCCC
VGDIIVYSAHWTNAGENKIINQDLSINGRNLNYYELNSRESMIYNLPIISSYSPTTPVIH
CCEEEEEEEECCCCCCCCEECCCCCCCCCCCEEEEECCCCCEEEECCEECCCCCCHHHHH
RVIDTWTDSEGNKYYITKGDNNPTYDPELIRAEQVRQRVVELNDEPFIIPYLGHISIILK
HHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCEEEEEEC
ENLIIFVILLVIWMYYDYRKEKVAKNN
CCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GGIINNKNILEWTVFLFVFLIVWTHVNVVVSDSMVPVMTRGDFVVVENSLFEFDPESVS
CCCCCCCCHHHHHHHHHHHHHHHHHCEEEEECCEEEEEECCCEEEEECCEEEECCCCCC
VGDIIVYSAHWTNAGENKIINQDLSINGRNLNYYELNSRESMIYNLPIISSYSPTTPVIH
CCEEEEEEEECCCCCCCCEECCCCCCCCCCCEEEEECCCCCEEEECCEECCCCCCHHHHH
RVIDTWTDSEGNKYYITKGDNNPTYDPELIRAEQVRQRVVELNDEPFIIPYLGHISIILK
HHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCEEEEEEC
ENLIIFVILLVIWMYYDYRKEKVAKNN
CCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]