| Definition | Methanococcus maripaludis S2 chromosome, complete genome. |
|---|---|
| Accession | NC_005791 |
| Length | 1,661,137 |
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The map label for this gene is metG [H]
Identifier: 45357889
GI number: 45357889
Start: 322398
End: 324389
Strand: Direct
Name: metG [H]
Synonym: MMP0326
Alternate gene names: 45357889
Gene position: 322398-324389 (Clockwise)
Preceding gene: 45357885
Following gene: 45357890
Centisome position: 19.41
GC content: 35.34
Gene sequence:
>1992_bases ATGAGGCATTTAGTTACAACTGCACTGGCATATACGAATGGACCCCTTCATCTTGGGCACGCGAGAAGTACCTACATTCC AGCAGACATCTTTACACGATATTTAAAACTAAAAGGCGAAGAAGTCATCCATGTTGGCGGAACAGACAATCACGGGGTTC CTATTACACTAACTGCTGAAAAAGAAGGTGTAAAACCGATTGATATTGTTGATAGGTACCACAATGCAATAAAAGCGGAC CTTGACAGTTTAAACATTTGTTTTGATAATTTTGGAAGGACACACAGCGATATACACATCGAAACTGCTCAGGAATTCTA TTCAAAATTAAAAGAAAATGGATATATCTACGAAAAAGAAATTGAACAGTTTTACTGTGAAAAATGTGACATGTACCTTG CAGACAGGTACGTTGAAGGAATCTGCCCATTTTGTGAAGGCGAAGCAAGAGGGGACCACTGTGAGGTTTGCGGAAGACAC CTTGAACCAACAGAACTTGTAAATCCTTACTGTATACACTGTAATTCAAAACCTGAAATCAAAAGAACTACCCACTATTT CTTTAAATTAAGTGCAATGCAGGATTCTTTAAAAGAATACATTGAAAATTCTCCAGAAATGCCGGAACACGTAAAAAATA TGGCTTTAAGATGGATTGAGGAACTTCACGACTGGGACGTTTCAAGAAACATAAAATGGGGAGTTCCAATTCCCGGATGT GATGATCAGGTGATGTACGTCTGGATTGAAGCTCCAATTGGATATGTATCATTTACAAAACAGCTTGGAGACATCTGGAA AAGCTACTGGCTTGAAAATACAGATGATTCGAAAATATCCCACTTTATTGGAAAGGACATTACAGTACACCACGCAGTAT TTTGGCCGGGAATTTTAAAAGGAATCGGCGGATACAAAATGCCAAACGCAGTTGTTAGCGGCGGTTACTTAACTCTTGAA AATAAAAAAATGAGTACAAGTAAAAACTGGGTTGTATGGGTTAAAGATTTTGTTGAAAACTTTAGTTCTGACTATTTAAG ATATTTCTTTATGATAAATGCTCCATTAAATAGAGATACCGACTTTTCATGGGACGATTTCCAAAAAAGGATTAATACTG AATTAATTGATATTATCGGAAACTTTACACACAGAACTTTAGTATTTACAGAACGTAAATTTGGCAGTACTCCGATTGTG GACTTAAACCAGTTAAAAGACGAAGATAAAAAGTTAATTTCAAAATGTGACGATACAGAAAAACTTGTTGATTCATTAAT TAGGGAATACAACTTTAAAGATGCATTAATGGAAATTATTCATTTGGCAAAAGAAGGAAACGGTTACTTCCAGGGAATGG CGCCATGGGCAATTAAAAATGAAGAAAGATTAAAAGAGGTAATGTACACATGTTCTGTTGTTTTAAAGTACATAATTTAC CTTTTAAGTTCATTCATGCCTGAAAAAACGGCTCTTCTTTTAGAATACATGAACGAAGAACTCGATTTAAAAGTTAGGGG AAATCCTCTTAAAAAACCGAAAGTTATATTTACCAAGGTAAGCGATGAAGATATTTCGAGAATGAAAGAAAACCTCATGA AAGCTACGAAAAAGGCCGAAACAAAATCAGACGAAAAGTCTAAAAAAGTAAAATCTGGTGAAAAAATGGATATTATTGAC ATTGATTACTTTGGAAACATTGATTTGAGAGTTGGACAGATTTTAGAAGTCGAAGAAGTTCCAAGATCAAAAAAACTCTA CAAAATTATCGCTGATTTGGGCGACGAAAAAAGACAGATTGTTTCTGGATTAATAGGAGCATATGATGCAGAAGAACTTG TTGGAAAAAAAGTAATAATAATCTGTAACTTAAAACCTGCAAAATTATGCGGTGTTGAGTCACAAGGAATGCTTTTAGCA GCAGAGGATGACAGTATTGTAAGTTTGTTATCACTTGATAGGGATCTTCCGGTTGGAAGCAAAATCCACTAA
Upstream 100 bases:
>100_bases TGAAAATCGGTTTTGAATTTCACAAATATATATTAATAAAATGTCTACAATTCATTTTGTACGAATGTTAATAAATTTTA CGATTATTTGGAGGATTAAG
Downstream 100 bases:
>100_bases TATTCTTTAAAATTATTATTTTTTGTTAAATTTCTTTTTTTATAAAATTTTTTAAAAAAGTTTTTATTTTAAGTTAGATA TAAACTGATTAGAGTTAATT
Product: methionyl-tRNA synthetase
Products: NA
Alternate protein names: Methionine--tRNA ligase; MetRS [H]
Number of amino acids: Translated: 663; Mature: 663
Protein sequence:
>663_residues MRHLVTTALAYTNGPLHLGHARSTYIPADIFTRYLKLKGEEVIHVGGTDNHGVPITLTAEKEGVKPIDIVDRYHNAIKAD LDSLNICFDNFGRTHSDIHIETAQEFYSKLKENGYIYEKEIEQFYCEKCDMYLADRYVEGICPFCEGEARGDHCEVCGRH LEPTELVNPYCIHCNSKPEIKRTTHYFFKLSAMQDSLKEYIENSPEMPEHVKNMALRWIEELHDWDVSRNIKWGVPIPGC DDQVMYVWIEAPIGYVSFTKQLGDIWKSYWLENTDDSKISHFIGKDITVHHAVFWPGILKGIGGYKMPNAVVSGGYLTLE NKKMSTSKNWVVWVKDFVENFSSDYLRYFFMINAPLNRDTDFSWDDFQKRINTELIDIIGNFTHRTLVFTERKFGSTPIV DLNQLKDEDKKLISKCDDTEKLVDSLIREYNFKDALMEIIHLAKEGNGYFQGMAPWAIKNEERLKEVMYTCSVVLKYIIY LLSSFMPEKTALLLEYMNEELDLKVRGNPLKKPKVIFTKVSDEDISRMKENLMKATKKAETKSDEKSKKVKSGEKMDIID IDYFGNIDLRVGQILEVEEVPRSKKLYKIIADLGDEKRQIVSGLIGAYDAEELVGKKVIIICNLKPAKLCGVESQGMLLA AEDDSIVSLLSLDRDLPVGSKIH
Sequences:
>Translated_663_residues MRHLVTTALAYTNGPLHLGHARSTYIPADIFTRYLKLKGEEVIHVGGTDNHGVPITLTAEKEGVKPIDIVDRYHNAIKAD LDSLNICFDNFGRTHSDIHIETAQEFYSKLKENGYIYEKEIEQFYCEKCDMYLADRYVEGICPFCEGEARGDHCEVCGRH LEPTELVNPYCIHCNSKPEIKRTTHYFFKLSAMQDSLKEYIENSPEMPEHVKNMALRWIEELHDWDVSRNIKWGVPIPGC DDQVMYVWIEAPIGYVSFTKQLGDIWKSYWLENTDDSKISHFIGKDITVHHAVFWPGILKGIGGYKMPNAVVSGGYLTLE NKKMSTSKNWVVWVKDFVENFSSDYLRYFFMINAPLNRDTDFSWDDFQKRINTELIDIIGNFTHRTLVFTERKFGSTPIV DLNQLKDEDKKLISKCDDTEKLVDSLIREYNFKDALMEIIHLAKEGNGYFQGMAPWAIKNEERLKEVMYTCSVVLKYIIY LLSSFMPEKTALLLEYMNEELDLKVRGNPLKKPKVIFTKVSDEDISRMKENLMKATKKAETKSDEKSKKVKSGEKMDIID IDYFGNIDLRVGQILEVEEVPRSKKLYKIIADLGDEKRQIVSGLIGAYDAEELVGKKVIIICNLKPAKLCGVESQGMLLA AEDDSIVSLLSLDRDLPVGSKIH >Mature_663_residues MRHLVTTALAYTNGPLHLGHARSTYIPADIFTRYLKLKGEEVIHVGGTDNHGVPITLTAEKEGVKPIDIVDRYHNAIKAD LDSLNICFDNFGRTHSDIHIETAQEFYSKLKENGYIYEKEIEQFYCEKCDMYLADRYVEGICPFCEGEARGDHCEVCGRH LEPTELVNPYCIHCNSKPEIKRTTHYFFKLSAMQDSLKEYIENSPEMPEHVKNMALRWIEELHDWDVSRNIKWGVPIPGC DDQVMYVWIEAPIGYVSFTKQLGDIWKSYWLENTDDSKISHFIGKDITVHHAVFWPGILKGIGGYKMPNAVVSGGYLTLE NKKMSTSKNWVVWVKDFVENFSSDYLRYFFMINAPLNRDTDFSWDDFQKRINTELIDIIGNFTHRTLVFTERKFGSTPIV DLNQLKDEDKKLISKCDDTEKLVDSLIREYNFKDALMEIIHLAKEGNGYFQGMAPWAIKNEERLKEVMYTCSVVLKYIIY LLSSFMPEKTALLLEYMNEELDLKVRGNPLKKPKVIFTKVSDEDISRMKENLMKATKKAETKSDEKSKKVKSGEKMDIID IDYFGNIDLRVGQILEVEEVPRSKKLYKIIADLGDEKRQIVSGLIGAYDAEELVGKKVIIICNLKPAKLCGVESQGMLLA AEDDSIVSLLSLDRDLPVGSKIH
Specific function: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation [H]
COG id: COG0143
COG function: function code J; Methionyl-tRNA synthetase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 tRNA-binding domain [H]
Homologues:
Organism=Homo sapiens, GI14043022, Length=506, Percent_Identity=31.8181818181818, Blast_Score=275, Evalue=1e-73, Organism=Homo sapiens, GI24308436, Length=525, Percent_Identity=26.2857142857143, Blast_Score=183, Evalue=4e-46, Organism=Homo sapiens, GI4507947, Length=96, Percent_Identity=44.7916666666667, Blast_Score=73, Evalue=7e-13, Organism=Escherichia coli, GI1788432, Length=657, Percent_Identity=32.2678843226788, Blast_Score=352, Evalue=3e-98, Organism=Escherichia coli, GI1789455, Length=109, Percent_Identity=38.5321100917431, Blast_Score=80, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17540794, Length=579, Percent_Identity=31.2607944732297, Blast_Score=306, Evalue=3e-83, Organism=Caenorhabditis elegans, GI212645096, Length=504, Percent_Identity=26.7857142857143, Blast_Score=179, Evalue=6e-45, Organism=Caenorhabditis elegans, GI71992781, Length=395, Percent_Identity=26.0759493670886, Blast_Score=133, Evalue=3e-31, Organism=Saccharomyces cerevisiae, GI6321704, Length=510, Percent_Identity=33.1372549019608, Blast_Score=269, Evalue=1e-72, Organism=Saccharomyces cerevisiae, GI6321610, Length=548, Percent_Identity=23.7226277372263, Blast_Score=128, Evalue=2e-30, Organism=Drosophila melanogaster, GI24655311, Length=556, Percent_Identity=32.1942446043165, Blast_Score=293, Evalue=2e-79, Organism=Drosophila melanogaster, GI21358483, Length=527, Percent_Identity=26.5654648956357, Blast_Score=164, Evalue=2e-40, Organism=Drosophila melanogaster, GI24651924, Length=101, Percent_Identity=38.6138613861386, Blast_Score=67, Evalue=5e-11,
Paralogues:
None
Copy number: 871 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR015413 - InterPro: IPR004495 - InterPro: IPR014758 - InterPro: IPR012340 - InterPro: IPR016027 - InterPro: IPR014729 - InterPro: IPR002547 - InterPro: IPR009080 - InterPro: IPR013155 [H]
Pfam domain/function: PF08264 Anticodon_1; PF09334 tRNA-synt_1g; PF01588 tRNA_bind [H]
EC number: =6.1.1.10 [H]
Molecular weight: Translated: 76174; Mature: 76174
Theoretical pI: Translated: 5.83; Mature: 5.83
Prosite motif: PS50886 TRBD ; PS00287 CYSTATIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.1 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 4.8 %Cys+Met (Translated Protein) 2.1 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 4.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRHLVTTALAYTNGPLHLGHARSTYIPADIFTRYLKLKGEEVIHVGGTDNHGVPITLTAE CCHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECC KEGVKPIDIVDRYHNAIKADLDSLNICFDNFGRTHSDIHIETAQEFYSKLKENGYIYEKE CCCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHCCCEEHHH IEQFYCEKCDMYLADRYVEGICPFCEGEARGDHCEVCGRHLEPTELVNPYCIHCNSKPEI HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCHHHHCCCEEEECCCCCCC KRTTHYFFKLSAMQDSLKEYIENSPEMPEHVKNMALRWIEELHDWDVSRNIKWGVPIPGC HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC DDQVMYVWIEAPIGYVSFTKQLGDIWKSYWLENTDDSKISHFIGKDITVHHAVFWPGILK CCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEHHHHHHHHHH GIGGYKMPNAVVSGGYLTLENKKMSTSKNWVVWVKDFVENFSSDYLRYFFMINAPLNRDT HCCCCCCCCCEECCCEEEEECCCCCCCCCEEEEHHHHHHHHHHHHEEEEEEEECCCCCCC DFSWDDFQKRINTELIDIIGNFTHRTLVFTERKFGSTPIVDLNQLKDEDKKLISKCDDTE CCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEHHHHCCHHHHHHHHCCCHH KLVDSLIREYNFKDALMEIIHLAKEGNGYFQGMAPWAIKNEERLKEVMYTCSVVLKYIIY HHHHHHHHHCCHHHHHHHHHHHHHCCCCEEECCCCCEECCHHHHHHHHHHHHHHHHHHHH LLSSFMPEKTALLLEYMNEELDLKVRGNPLKKPKVIFTKVSDEDISRMKENLMKATKKAE HHHHHCCHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHH TKSDEKSKKVKSGEKMDIIDIDYFGNIDLRVGQILEVEEVPRSKKLYKIIADLGDEKRQI CCCHHHHHHHCCCCCEEEEEEECCCCCEEECCCEEEHHHCCCHHHHHHHHHHCCHHHHHH VSGLIGAYDAEELVGKKVIIICNLKPAKLCGVESQGMLLAAEDDSIVSLLSLDRDLPVGS HHHHHCCCCHHHHCCCEEEEEECCCCHHHCCCCCCCEEEEECCCCHHHHHHCCCCCCCCC KIH CCC >Mature Secondary Structure MRHLVTTALAYTNGPLHLGHARSTYIPADIFTRYLKLKGEEVIHVGGTDNHGVPITLTAE CCHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECC KEGVKPIDIVDRYHNAIKADLDSLNICFDNFGRTHSDIHIETAQEFYSKLKENGYIYEKE CCCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHCCCEEHHH IEQFYCEKCDMYLADRYVEGICPFCEGEARGDHCEVCGRHLEPTELVNPYCIHCNSKPEI HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCHHHHCCCEEEECCCCCCC KRTTHYFFKLSAMQDSLKEYIENSPEMPEHVKNMALRWIEELHDWDVSRNIKWGVPIPGC HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC DDQVMYVWIEAPIGYVSFTKQLGDIWKSYWLENTDDSKISHFIGKDITVHHAVFWPGILK CCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEHHHHHHHHHH GIGGYKMPNAVVSGGYLTLENKKMSTSKNWVVWVKDFVENFSSDYLRYFFMINAPLNRDT HCCCCCCCCCEECCCEEEEECCCCCCCCCEEEEHHHHHHHHHHHHEEEEEEEECCCCCCC DFSWDDFQKRINTELIDIIGNFTHRTLVFTERKFGSTPIVDLNQLKDEDKKLISKCDDTE CCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEHHHHCCHHHHHHHHCCCHH KLVDSLIREYNFKDALMEIIHLAKEGNGYFQGMAPWAIKNEERLKEVMYTCSVVLKYIIY HHHHHHHHHCCHHHHHHHHHHHHHCCCCEEECCCCCEECCHHHHHHHHHHHHHHHHHHHH LLSSFMPEKTALLLEYMNEELDLKVRGNPLKKPKVIFTKVSDEDISRMKENLMKATKKAE HHHHHCCHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHH TKSDEKSKKVKSGEKMDIIDIDYFGNIDLRVGQILEVEEVPRSKKLYKIIADLGDEKRQI CCCHHHHHHHCCCCCEEEEEEECCCCCEEECCCEEEHHHCCCHHHHHHHHHHCCHHHHHH VSGLIGAYDAEELVGKKVIIICNLKPAKLCGVESQGMLLAAEDDSIVSLLSLDRDLPVGS HHHHHCCCCHHHHCCCEEEEEECCCCHHHCCCCCCCEEEEECCCCHHHHHHCCCCCCCCC KIH CCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA