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The map label for this gene is MscMJ [C]

Identifier: 45357827

GI number: 45357827

Start: 264845

End: 265900

Strand: Direct

Name: MscMJ [C]

Synonym: MMP0264

Alternate gene names: 45357827

Gene position: 264845-265900 (Clockwise)

Preceding gene: 45357826

Following gene: 45357828

Centisome position: 15.94

GC content: 32.39

Gene sequence:

>1056_bases
ATGGCGTTAGATCAATTATATTTTGGAAATACCCTGTATTCATACATGATATTTTTAATATTCATATTTTTCGGGGTATT
CTTTGGAAAAGTAATGTACATATTTTTAAATAAGTACGTAAGAGTTCTTGCAGGAAAAACAAAAACTAAATTAGATGATG
TAGTACTTGATGCAGTAGAAATCCCCTTAATAATTGTGGTTTTCGTTTTATTTTTCAAGTATGGATTAAATAATTTAGTT
TTACCCGATAATTTATCTTTGTGGCTCAATGAATCTTTAACTGTGGCAATAACCTTTGCAGGAGTTTTATTTTTACTTAA
AATTGTGGATGATATAATTGTAAATTATGTTGTCCCAATCGTAGAAAAGTCAGAAAATACGCTCGACGACCAGCTTGTTC
CATTAATGAGAAAACTGGTCAAATTTTTGATTTTGATTGCAGGGCTCATGCTTATTTTATCAAATGTCGGTTACAACATT
TCAGCACTTCTCGCAGGGCTTGGTATCGGCGGTTTGGCAGTTGCGCTTGCTGCAAAGGACACGATTGAAAATTTAATTGC
AGGATTTATTATAATTGTTGATAGACCTTTTAAATTGGGCGACTGGATAAAATGGGGCGGAAAAGAGGGAATTGTAGAAG
AGGTAGGAATTAGAAGTACTCGTGTTCGTTCATTTGGGGACACATTAATTACAGTTCCAAACGCAAATATCGTTCAAACT
GAAATTGAAAACTTTTCAGAAAGGAGAAAAAGACAGGTAAAAGCAACAATCGGTTTAACTTACGACACGCCAGTAGAAAA
AGTAAAACGTGCAAAAGAAATAATAGAAAACGTTTTAAATGATCATCATGGCGTTGTAGATCCAATAAGGGTATCATTTG
TTGAATTTGGCAGTTTTTCACTTGATTTAAGAGTTGAATACTTTGTAAGGGATTTCGGGTTTGATTTCTTCTTAAATACC
AAGGATGAAATAAATATCAAAATAAAAGAAGAATTTGAGAAAGAAAATATTGAATTTGCATTCCCTACACAGACAGTATA
CTACAAAAAAGAATAA

Upstream 100 bases:

>100_bases
TTCACCCAATGGATGTTAAAAACCTCGTTTCAGAACAATTAATTGAAATTTTAAGACCTATCCGCGAAAAAATGAATAAA
TAAGGATAAATAGTGAAATT

Downstream 100 bases:

>100_bases
TTAGATTTTATTTTTATATTTTTTAAGGGAAAATTATGGATAGGACCTGGGCGTTAATTTTTGCAATTGTTGTTGGATTT
GTAGCATCACTTCAGCCGAT

Product: mechanosensitive ion channel MscS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MALDQLYFGNTLYSYMIFLIFIFFGVFFGKVMYIFLNKYVRVLAGKTKTKLDDVVLDAVEIPLIIVVFVLFFKYGLNNLV
LPDNLSLWLNESLTVAITFAGVLFLLKIVDDIIVNYVVPIVEKSENTLDDQLVPLMRKLVKFLILIAGLMLILSNVGYNI
SALLAGLGIGGLAVALAAKDTIENLIAGFIIIVDRPFKLGDWIKWGGKEGIVEEVGIRSTRVRSFGDTLITVPNANIVQT
EIENFSERRKRQVKATIGLTYDTPVEKVKRAKEIIENVLNDHHGVVDPIRVSFVEFGSFSLDLRVEYFVRDFGFDFFLNT
KDEINIKIKEEFEKENIEFAFPTQTVYYKKE

Sequences:

>Translated_351_residues
MALDQLYFGNTLYSYMIFLIFIFFGVFFGKVMYIFLNKYVRVLAGKTKTKLDDVVLDAVEIPLIIVVFVLFFKYGLNNLV
LPDNLSLWLNESLTVAITFAGVLFLLKIVDDIIVNYVVPIVEKSENTLDDQLVPLMRKLVKFLILIAGLMLILSNVGYNI
SALLAGLGIGGLAVALAAKDTIENLIAGFIIIVDRPFKLGDWIKWGGKEGIVEEVGIRSTRVRSFGDTLITVPNANIVQT
EIENFSERRKRQVKATIGLTYDTPVEKVKRAKEIIENVLNDHHGVVDPIRVSFVEFGSFSLDLRVEYFVRDFGFDFFLNT
KDEINIKIKEEFEKENIEFAFPTQTVYYKKE
>Mature_350_residues
ALDQLYFGNTLYSYMIFLIFIFFGVFFGKVMYIFLNKYVRVLAGKTKTKLDDVVLDAVEIPLIIVVFVLFFKYGLNNLVL
PDNLSLWLNESLTVAITFAGVLFLLKIVDDIIVNYVVPIVEKSENTLDDQLVPLMRKLVKFLILIAGLMLILSNVGYNIS
ALLAGLGIGGLAVALAAKDTIENLIAGFIIIVDRPFKLGDWIKWGGKEGIVEEVGIRSTRVRSFGDTLITVPNANIVQTE
IENFSERRKRQVKATIGLTYDTPVEKVKRAKEIIENVLNDHHGVVDPIRVSFVEFGSFSLDLRVEYFVRDFGFDFFLNTK
DEINIKIKEEFEKENIEFAFPTQTVYYKKE

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1787591, Length=217, Percent_Identity=31.7972350230415, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789291, Length=231, Percent_Identity=29.8701298701299, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1786670, Length=219, Percent_Identity=24.6575342465753, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 39899; Mature: 39768

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALDQLYFGNTLYSYMIFLIFIFFGVFFGKVMYIFLNKYVRVLAGKTKTKLDDVVLDAVE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IPLIIVVFVLFFKYGLNNLVLPDNLSLWLNESLTVAITFAGVLFLLKIVDDIIVNYVVPI
HHHHHHHHHHHHHHCCCCEECCCCCCEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
VEKSENTLDDQLVPLMRKLVKFLILIAGLMLILSNVGYNISALLAGLGIGGLAVALAAKD
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHH
TIENLIAGFIIIVDRPFKLGDWIKWGGKEGIVEEVGIRSTRVRSFGDTLITVPNANIVQT
HHHHHHHCEEEEEECCCCCCCHHHCCCCCCCHHHHCCCHHHHHHCCCEEEECCCCCCHHH
EIENFSERRKRQVKATIGLTYDTPVEKVKRAKEIIENVLNDHHGVVDPIRVSFVEFGSFS
HHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEE
LDLRVEYFVRDFGFDFFLNTKDEINIKIKEEFEKENIEFAFPTQTVYYKKE
EEEEHHHHHHHCCCEEEECCCCCEEEEEEEHHCCCCCEEECCCCEEEEECC
>Mature Secondary Structure 
ALDQLYFGNTLYSYMIFLIFIFFGVFFGKVMYIFLNKYVRVLAGKTKTKLDDVVLDAVE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IPLIIVVFVLFFKYGLNNLVLPDNLSLWLNESLTVAITFAGVLFLLKIVDDIIVNYVVPI
HHHHHHHHHHHHHHCCCCEECCCCCCEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
VEKSENTLDDQLVPLMRKLVKFLILIAGLMLILSNVGYNISALLAGLGIGGLAVALAAKD
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHH
TIENLIAGFIIIVDRPFKLGDWIKWGGKEGIVEEVGIRSTRVRSFGDTLITVPNANIVQT
HHHHHHHCEEEEEECCCCCCCHHHCCCCCCCHHHHCCCHHHHHHCCCEEEECCCCCCHHH
EIENFSERRKRQVKATIGLTYDTPVEKVKRAKEIIENVLNDHHGVVDPIRVSFVEFGSFS
HHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEE
LDLRVEYFVRDFGFDFFLNTKDEINIKIKEEFEKENIEFAFPTQTVYYKKE
EEEEHHHHHHHCCCEEEECCCCCEEEEEEEHHCCCCCEEECCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]