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The map label for this gene is thrC [H]

Identifier: 45357698

GI number: 45357698

Start: 141612

End: 142826

Strand: Direct

Name: thrC [H]

Synonym: MMP0135

Alternate gene names: 45357698

Gene position: 141612-142826 (Clockwise)

Preceding gene: 45357697

Following gene: 45357699

Centisome position: 8.53

GC content: 37.53

Gene sequence:

>1215_bases
ATGATTCAAAAATGCAGAGTATGCGGAAAAGAATACGATGTTGATGCCATAATTTACAACTGCGAATGTGGCGGATTACT
CGAAATTAAATACGATTTTGAAAGTATCAAAGAAAAAGTTTCAAAAGAATCCTTAAGGGAAAGAGAACTTGGTGTATGGA
GATATTTAGACTACTTACCAGTTAAAGATCCTGCAAAAATTGTGAGCCTTCACGAAGGGGGAACTCCACTTTACAAATGT
GAAAATCTCGCAAAAAAATTAGGAATGAAAGAGTTATATGTTAAAAACGAAGGTGCAAACCCAACAGGAAGTTTCAAAGA
TAGAGGGATGACTGTTGGAGTTACAAGAGCAAACGAACTTGGTGTTGAAGTAGTAGGCTGTGCTTCAACCGGAAACACAT
CTGCATCACTTGCAGCATACTCTGCAAGAGCAGGTAAAAAATGTATTGTTCTTCTTCCTGGAGGAAAAGTAGCTCTTGGA
AAACTCGCTCAGGCAATGTTTTACGGTGCAAAAGTTATCCAGATCAACGGAAACTTTGACGAAGCTCTTGTAATGGTTAA
AAACCTTGCATTAGAAAACAAACTCTACTTATTAAACTCTGTAAACCCATTCAGACTTGAAGGTCAGAAAACAATTGGTT
TTGAAATCTGCGACCAGTTAGACTTTGAAGTTCCAGACATGGTTATTTTACCGGTTGGAAACGCTGGAAACATCAGCGCA
ATCTGGAAAGGATTTAAAGAATTTAAAGAAACAGAAATGATTGACAGATTACCAAAAATGACTGGAATCCAAGCAGAAGG
TGCACAGCCAATTGTAAAAGCGATAAAAGAAGGACTCGACGAAATAGTTCCTGACGAAAATCCTGAAACAATTGCAACTG
CAATCAGAATCGGAAACCCTGTAAACGCTGCAAAAGCACTTGATGCAATCAAATCTTCAGGAGGGCTTGCAGAAAGCGTA
AACGATGAAGAAATTATCGAAGCTCAGAAACTCCTTGCACAAACAGAAGGAATTTTCGTAGAACCTGCTTCAGCATCATC
AATTGCAGGTCTTATCAAATTGATAAACATGGGATTAATTGATAAAGATCAAAAAATCGTATGTATTACAACAGGTAACG
GATTAAAAGATCCAGATGCTGCAATCAAAGCAAGTAAAATGCCTACAGAAATTGAATGCGACATGGAAGTACTCAGAAAA
GCAATAGAAGAATAA

Upstream 100 bases:

>100_bases
TTTGAAGACTCGTTTTATTAATTTCAAAGTTCCATGATTAATGATACATTTATATTTTATAATTTGATAGTGGTATTCAA
TCAAGATAACAAGTGAGAAT

Downstream 100 bases:

>100_bases
TTAAATCTGGTGGAATTATGAAAAAGACTGTCGAAGGCAAAGCATGGGTTTTTGGAGATAACATCGATACTGATGCAATA
TTACCTGCAAGATACCTTGT

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MIQKCRVCGKEYDVDAIIYNCECGGLLEIKYDFESIKEKVSKESLRERELGVWRYLDYLPVKDPAKIVSLHEGGTPLYKC
ENLAKKLGMKELYVKNEGANPTGSFKDRGMTVGVTRANELGVEVVGCASTGNTSASLAAYSARAGKKCIVLLPGGKVALG
KLAQAMFYGAKVIQINGNFDEALVMVKNLALENKLYLLNSVNPFRLEGQKTIGFEICDQLDFEVPDMVILPVGNAGNISA
IWKGFKEFKETEMIDRLPKMTGIQAEGAQPIVKAIKEGLDEIVPDENPETIATAIRIGNPVNAAKALDAIKSSGGLAESV
NDEEIIEAQKLLAQTEGIFVEPASASSIAGLIKLINMGLIDKDQKIVCITTGNGLKDPDAAIKASKMPTEIECDMEVLRK
AIEE

Sequences:

>Translated_404_residues
MIQKCRVCGKEYDVDAIIYNCECGGLLEIKYDFESIKEKVSKESLRERELGVWRYLDYLPVKDPAKIVSLHEGGTPLYKC
ENLAKKLGMKELYVKNEGANPTGSFKDRGMTVGVTRANELGVEVVGCASTGNTSASLAAYSARAGKKCIVLLPGGKVALG
KLAQAMFYGAKVIQINGNFDEALVMVKNLALENKLYLLNSVNPFRLEGQKTIGFEICDQLDFEVPDMVILPVGNAGNISA
IWKGFKEFKETEMIDRLPKMTGIQAEGAQPIVKAIKEGLDEIVPDENPETIATAIRIGNPVNAAKALDAIKSSGGLAESV
NDEEIIEAQKLLAQTEGIFVEPASASSIAGLIKLINMGLIDKDQKIVCITTGNGLKDPDAAIKASKMPTEIECDMEVLRK
AIEE
>Mature_404_residues
MIQKCRVCGKEYDVDAIIYNCECGGLLEIKYDFESIKEKVSKESLRERELGVWRYLDYLPVKDPAKIVSLHEGGTPLYKC
ENLAKKLGMKELYVKNEGANPTGSFKDRGMTVGVTRANELGVEVVGCASTGNTSASLAAYSARAGKKCIVLLPGGKVALG
KLAQAMFYGAKVIQINGNFDEALVMVKNLALENKLYLLNSVNPFRLEGQKTIGFEICDQLDFEVPDMVILPVGNAGNISA
IWKGFKEFKETEMIDRLPKMTGIQAEGAQPIVKAIKEGLDEIVPDENPETIATAIRIGNPVNAAKALDAIKSSGGLAESV
NDEEIIEAQKLLAQTEGIFVEPASASSIAGLIKLINMGLIDKDQKIVCITTGNGLKDPDAAIKASKMPTEIECDMEVLRK
AIEE

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: 1344 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 43782; Mature: 43782

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQKCRVCGKEYDVDAIIYNCECGGLLEIKYDFESIKEKVSKESLRERELGVWRYLDYLP
CCCHHHHCCCCCCCEEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHHHCCHHHHHHCCC
VKDPAKIVSLHEGGTPLYKCENLAKKLGMKELYVKNEGANPTGSFKDRGMTVGVTRANEL
CCCCHHEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCC
GVEVVGCASTGNTSASLAAYSARAGKKCIVLLPGGKVALGKLAQAMFYGAKVIQINGNFD
CEEEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCHH
EALVMVKNLALENKLYLLNSVNPFRLEGQKTIGFEICDQLDFEVPDMVILPVGNAGNISA
HHHHHHHHHHHCCCEEEEECCCCEEECCCCEECHHHHHHCCCCCCCEEEEECCCCCCHHH
IWKGFKEFKETEMIDRLPKMTGIQAEGAQPIVKAIKEGLDEIVPDENPETIATAIRIGNP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
VNAAKALDAIKSSGGLAESVNDEEIIEAQKLLAQTEGIFVEPASASSIAGLIKLINMGLI
CHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHCCCC
DKDQKIVCITTGNGLKDPDAAIKASKMPTEIECDMEVLRKAIEE
CCCCEEEEEECCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MIQKCRVCGKEYDVDAIIYNCECGGLLEIKYDFESIKEKVSKESLRERELGVWRYLDYLP
CCCHHHHCCCCCCCEEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHHHCCHHHHHHCCC
VKDPAKIVSLHEGGTPLYKCENLAKKLGMKELYVKNEGANPTGSFKDRGMTVGVTRANEL
CCCCHHEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCC
GVEVVGCASTGNTSASLAAYSARAGKKCIVLLPGGKVALGKLAQAMFYGAKVIQINGNFD
CEEEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCHH
EALVMVKNLALENKLYLLNSVNPFRLEGQKTIGFEICDQLDFEVPDMVILPVGNAGNISA
HHHHHHHHHHHCCCEEEEECCCCEEECCCCEECHHHHHHCCCCCCCEEEEECCCCCCHHH
IWKGFKEFKETEMIDRLPKMTGIQAEGAQPIVKAIKEGLDEIVPDENPETIATAIRIGNP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
VNAAKALDAIKSSGGLAESVNDEEIIEAQKLLAQTEGIFVEPASASSIAGLIKLINMGLI
CHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHCCCC
DKDQKIVCITTGNGLKDPDAAIKASKMPTEIECDMEVLRKAIEE
CCCCEEEEEECCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]