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The map label for this gene is argC [H]

Identifier: 45357679

GI number: 45357679

Start: 124154

End: 125185

Strand: Direct

Name: argC [H]

Synonym: MMP0116

Alternate gene names: 45357679

Gene position: 124154-125185 (Clockwise)

Preceding gene: 45357678

Following gene: 45357686

Centisome position: 7.47

GC content: 38.37

Gene sequence:

>1032_bases
ATGAAAACAGTTTCGATAATAGGCGGAACGGGGTATACGGGCTCAGAACTTTTAAGACTCCTTTCAAACCACGACGAAGT
TGAAGTTGTGAATGTAACATCAAGAAAGGAAGCTGGAAAAAATCTCACTGATTATCACCCTCAGGTCAGAAATTTAAGTA
ACTATAACGATTTAAAATTCCAAAATATTGCTCCAGAAGATATCGATTCTGATATCGTGTTCTGTGCAACACCACACGGT
GCGTCAATGGCAATTGTCCCGACACTGCACGAAAAAGGAATAAATGTAATCGATTTAAGCGGGGATTACAGGTTTGAAGA
TATTGATATGTATGAATCATGGTATGGATTGAAACACTCTGGAAAAATAGATTCTGCAGTTTACGGCCTTCCTGAACTTC
ACCGGGAAAAAATAAAAAAGTCAAAAACAATTGCAAATCCGGGATGCTACCCAACAGGAGCAATTCTTTCAATGGCGCCA
TTGGTTGCAAATGATCTCGTTGAAGACAGGATAATTTTTGATTCAAAATCGGGAGTAAGTGGTGCAGGTGTCGAAGCAAG
TCAAACTACCCATTTTGCAAATGTAAATGAAAATATCGGACCCTACAAAATAACGAAACACAGACACAGTCCCGAAATTG
GAAAAGAGCTTCAATATCTTGCAAACAAAAATTTGAAAGTTTCATTTACTCCTCACCTTCTGCCAGTTACACGGGGAATA
TTAACTACTGCGCATTCATTCCTTAAAGAGGATATAAGTCCAATAGATGTTATCGAAATTTACGAAGAATTCTACAAAGA
CGAATTTTTCATAAGAATTTTCGAAGAAGGAATGCCTTCATTAACGGGAGTTCGAGGAACCAACTTCTGCGACATTGGCG
GATTTGAAATTGACCAATATGGCAGAATTGTTGTAGTTTCAGCAATAGACAATTTAGTAAAAGGAGCAAGTGGTCAAGCA
ATCCAGAACATGAATATTATCATGGGATTCGATGAAAAAGAGGGTTTAGGCGTTGGCGGGCTTAAGCCTTAA

Upstream 100 bases:

>100_bases
TTATGGGGGTGGTTATTTTAAAGATAATCATTACTTTTTTATCCCATCAAGTTTTAATTTATACAGCAAAATTTTCGCAT
TATTCTAAAAGGTGGTTTTA

Downstream 100 bases:

>100_bases
CTTAAATTTTAAAAATATTTTATTTATTTTCTTATTACATTAAATCTTCCGGCAGAGGAATGTTTTGGAAGCACATCTAC
ACCGAGGCTTTTTAAATAAG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MKTVSIIGGTGYTGSELLRLLSNHDEVEVVNVTSRKEAGKNLTDYHPQVRNLSNYNDLKFQNIAPEDIDSDIVFCATPHG
ASMAIVPTLHEKGINVIDLSGDYRFEDIDMYESWYGLKHSGKIDSAVYGLPELHREKIKKSKTIANPGCYPTGAILSMAP
LVANDLVEDRIIFDSKSGVSGAGVEASQTTHFANVNENIGPYKITKHRHSPEIGKELQYLANKNLKVSFTPHLLPVTRGI
LTTAHSFLKEDISPIDVIEIYEEFYKDEFFIRIFEEGMPSLTGVRGTNFCDIGGFEIDQYGRIVVVSAIDNLVKGASGQA
IQNMNIIMGFDEKEGLGVGGLKP

Sequences:

>Translated_343_residues
MKTVSIIGGTGYTGSELLRLLSNHDEVEVVNVTSRKEAGKNLTDYHPQVRNLSNYNDLKFQNIAPEDIDSDIVFCATPHG
ASMAIVPTLHEKGINVIDLSGDYRFEDIDMYESWYGLKHSGKIDSAVYGLPELHREKIKKSKTIANPGCYPTGAILSMAP
LVANDLVEDRIIFDSKSGVSGAGVEASQTTHFANVNENIGPYKITKHRHSPEIGKELQYLANKNLKVSFTPHLLPVTRGI
LTTAHSFLKEDISPIDVIEIYEEFYKDEFFIRIFEEGMPSLTGVRGTNFCDIGGFEIDQYGRIVVVSAIDNLVKGASGQA
IQNMNIIMGFDEKEGLGVGGLKP
>Mature_343_residues
MKTVSIIGGTGYTGSELLRLLSNHDEVEVVNVTSRKEAGKNLTDYHPQVRNLSNYNDLKFQNIAPEDIDSDIVFCATPHG
ASMAIVPTLHEKGINVIDLSGDYRFEDIDMYESWYGLKHSGKIDSAVYGLPELHREKIKKSKTIANPGCYPTGAILSMAP
LVANDLVEDRIIFDSKSGVSGAGVEASQTTHFANVNENIGPYKITKHRHSPEIGKELQYLANKNLKVSFTPHLLPVTRGI
LTTAHSFLKEDISPIDVIEIYEEFYKDEFFIRIFEEGMPSLTGVRGTNFCDIGGFEIDQYGRIVVVSAIDNLVKGASGQA
IQNMNIIMGFDEKEGLGVGGLKP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=343, Percent_Identity=35.8600583090379, Blast_Score=207, Evalue=6e-55,
Organism=Saccharomyces cerevisiae, GI6320913, Length=342, Percent_Identity=34.5029239766082, Blast_Score=150, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 37784; Mature: 37784

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVSIIGGTGYTGSELLRLLSNHDEVEVVNVTSRKEAGKNLTDYHPQVRNLSNYNDLKF
CCEEEEECCCCCCHHHHHHHHCCCCCEEEEEECCHHHHCCCCHHCCHHHHCCCCCCCEEE
QNIAPEDIDSDIVFCATPHGASMAIVPTLHEKGINVIDLSGDYRFEDIDMYESWYGLKHS
CCCCCCCCCCCEEEEECCCCCCEEEEECHHHCCCCEEECCCCCCCCHHHHHHHHCCCCCC
GKIDSAVYGLPELHREKIKKSKTIANPGCYPTGAILSMAPLVANDLVEDRIIFDSKSGVS
CCCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCC
GAGVEASQTTHFANVNENIGPYKITKHRHSPEIGKELQYLANKNLKVSFTPHLLPVTRGI
CCCCCCCCCEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHH
LTTAHSFLKEDISPIDVIEIYEEFYKDEFFIRIFEEGMPSLTGVRGTNFCDIGGFEIDQY
HHHHHHHHHHCCCCHHHHHHHHHHHCCHHEEHHHHHCCCCCCCCCCCCEEECCCEEECCC
GRIVVVSAIDNLVKGASGQAIQNMNIIMGFDEKEGLGVGGLKP
CCEEEEEHHHHHHCCCCCCEEECCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MKTVSIIGGTGYTGSELLRLLSNHDEVEVVNVTSRKEAGKNLTDYHPQVRNLSNYNDLKF
CCEEEEECCCCCCHHHHHHHHCCCCCEEEEEECCHHHHCCCCHHCCHHHHCCCCCCCEEE
QNIAPEDIDSDIVFCATPHGASMAIVPTLHEKGINVIDLSGDYRFEDIDMYESWYGLKHS
CCCCCCCCCCCEEEEECCCCCCEEEEECHHHCCCCEEECCCCCCCCHHHHHHHHCCCCCC
GKIDSAVYGLPELHREKIKKSKTIANPGCYPTGAILSMAPLVANDLVEDRIIFDSKSGVS
CCCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCC
GAGVEASQTTHFANVNENIGPYKITKHRHSPEIGKELQYLANKNLKVSFTPHLLPVTRGI
CCCCCCCCCEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHH
LTTAHSFLKEDISPIDVIEIYEEFYKDEFFIRIFEEGMPSLTGVRGTNFCDIGGFEIDQY
HHHHHHHHHHCCCCHHHHHHHHHHHCCHHEEHHHHHCCCCCCCCCCCCEEECCCEEECCC
GRIVVVSAIDNLVKGASGQAIQNMNIIMGFDEKEGLGVGGLKP
CCEEEEEHHHHHHCCCCCCEEECCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA